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Volume 1 Issue 3 - 2015 | Surgery and Surgical Research | 2455-2968

Open Access Article Type: Perspective

EGFR Inhibitors for Neoadjuvant and Adjuvant Therapy of NSCLC

5-year survival rates of Non-Small Cell Lung Cancer (NSCLC) remain unsatisfactory after surgery with curative intent and disease recurrences, including distant metastases, are frequent. Only a minority of this heterogeneous disease is positive for EGFR mutations and suitable for Tyrosine Kinase-Inhibitor biological agents, which however present limits in terms of stable response to treatment, due to the acquired drug resistances.

Readmore... DOI: 10.17352/2455-2968.000019

Open Access Article Type: Case Report

Aberrant Ulnar Artery and Ulnar Artery Thrombosis with Nerve Entrapment: A Case Report

Introduction: Vascular compromise causes hand pain, and physical examination requires to differentiate vascular causes from isolated ulnar nerve compression. Diagnostic studies visualize vascular abnormalities such as CT scans, MRA scans, and AV fistulograms.

Readmore... DOI: 10.17352/2455-2968.000017

Open Access Article Type: Research Article

Total Knee Prosthesis after Knee Joint Distraction Treatment

Background and purpose: During knee joint distraction (KJD) treatment, using an external fixation-frame, pin-tract infections frequently occur. These local skin infections, although treated successfully with oral antibiotics, might lead to latent infections. This raises concern about subsequent placement of a total knee prosthesis (TKP). This study evaluates the first five cases in which patients had to be treated with TKO after KJD failure.

Readmore... DOI: 10.17352/2455-2968.000016

Open Access Article Type: Case Report

Cystic Echinococcosis in the Liver: Nomenclature and Surgical Procedures

Cystic Echinococcosis (CE) is a zoonotic infection caused by larval form of the parasite Echinococcus granulosus. The adult tapeworm inhabit the small intestine of some carnivores (called definitive or final hosts), and the larval phase, or "metacestode" develops in the herbivores (intermediate hosts).

Readmore... DOI: 10.17352/2455-2968.000015

Open Access Article Type: Research Article

The Neuroendocrine Cancer. Personal Comments and Operational Remarks

Indroduction: Neuroendocrine tumors (NEN) of the gastro-entero-pancreatic tract (GEP) are a group in themselves very heterogeneous of tumors that are different for the site of localization in the digestive tract (foregut, midgut and hindgut), both in relation to the pathological aspects, functional activity and nosographic classification.

Readmore... DOI: 10.17352/2455-2968.000014

Open Access Article Type: Research Article

HER2 Status in Male Breast Carcinoma: a Single North African Institution Experience of 10 Cases and Review of the Literature

Background: To investigate clinic-pathological characteristics, hormonal receptors and HER2 receptor of male breast cancer.
Materials and methods: Retrospective study of 10 cases between 2010 and 2013. The studied parameters were: tumor size, histological type, histological grade, lymph node status, hormonal status and overexpression of HER2.

Readmore... DOI: 10.17352/2455-2968.000013

Open Access Article Type: Research Article

The Stent Evolution in Colo-Rectal Emergencies

Introduction: The appearance of a framework for occlusive colorectal tumor raises complex issues and difficult. We need to ensure a resumption of normal bowel function in patients often in extreme conditions. Emergency surgery flounders in a derivation and a resection with restoration of intestinal transit.

Readmore... DOI: 10.17352/2455-2968.000012

Open Access Article Type: Research Article

Muscle-Sparing Thoracotomy: A Systematic Literature Review and the "Ave" Classification

Background: To synthesize the concept of muscle-sparing thoracotomies for major pulmonary resections and to explore the relationship between Kraissl's lines and skin incisions perpendicular to them.
Methods: Systematic literature review was performed of MEDLINE database. Articles were selected if they described adult patients undergoing major pulmonary resection by way of a well-described thoracotomy that neither partially nor completely transects extra thoracic muscles, and that is independent of endoscopic instruments, and video technology. Median sternotomy was excluded.

Readmore... DOI: 10.17352/2455-2968.000011


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