Hanane Atarguine1*, Soundous Benmoussa2, Fayçal Abbad3, Ouafa Hocar1, Fatima Ihbibane2, Hanane Rais3, Noura Tassi2, Nadia Akhdari1 and Said Amal1
1Department of Dermatology, Hospital Arrazi, CHU Mohamed VI, Marrakech, Maroco 2Department of Infectious Diseases, Hospital Arrazi, CHU Mohamed VI, Marrakech, Maroco 3Department of Pathological Anatomy and Cytology, CHU Mohamed VI, Marrakech, Maroco
Received: 21 January, 2016; Accepted: 08 February, 2016; Published: 10 February, 2016
Dr, Hanane Atarguine, Department of Dermatology, Hospital Arrazi, CHU Mohamed VI, 40000 Marrakech, Maroco, Tel: +212672691777; E-mail:
Atarguine H, Benmoussa S, Abbad F, Hocar O, Ihbibane F, et al. (2016) Acquired Immunodeficiency Syndrome Revealed by Oral Kaposi’s Sarcoma. Int J Oral Craniofac Sci 2(1): 001-002. DOI: 10.17352/2455-4634.000010
© 2016 Atarguine H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Kaposi′s sarcoma; Oral; Acquired immunodeficiency syndrome; HIV
Kaposi’s sarcoma is the malignant proliferation of the endothelial cell vessels. It is a systemic, malignant and multifactor disease. It usually presents initially as violaceous cutaneous lesions. Outside of a known context of an immune deficiency, an isolated oral lesions may not think to Kaposi’s sarcoma. Hence the interest of the histological and immunohistochemical study.
This paper reviews one such case of Kaposi’s sarcoma in a 42-year-old woman who present an isolated pigmented lesions of the tongue, related to Kaposi’s sarcoma, without cutaneous or visceral involvement, and which led to the discovery of acquired immunodeficiency syndrome (HIV). The stabilization was obtained with antiretroviral triple therapy.
Kaposi’s Sarcoma (KS), being first described in 1872 , is an unusual vascular neoplasm that most likely arises from endothelial cells, with some evidence of lymphatic origin. Different clinical and epidemiological variants have been identified. Lesions of KS typically manifests as bluish-purple macules and plaques on the skin, particularly of the face and lower extremities. Oral mucosa, lymph nodes and visceral organs may be affected, sometimes without cutaneous involvement.
Here, we report the case of a 42-year-old female, having pigmented macules of the tongue, without other sites, revealing Kaposi’s sarcoma an acquired immunodeficiency syndrome with good response to antiretroviral triple therapy.
A 42-year-old married woman, without specific medical history, was referred to our service for the evaluation of a pigmented lesion of the tongue, painless, non-pruritic and without changing of the taste that had appeared 20 days earlier. In the course of disease, she had a fever, diarrhea and weight loss.
Oral examination shows a confluent brownish macules bunched at the tongue, without other associated lesions of the oral cavity (Figure 1). No other similar lesions in any other region of the body were detected. Lymphadenopathy was not detected and physical examination showed no abnormalities.