Abstract

    Open Access Review Article Article ID: ACMPH-4-139

    How to induce, generate and control Immunological Anomalies in humans?

    Philip Ifesinachi Anochie*, Godwin Okeke Kalu, Mfon Itoro- Obong Akpan, Augustine Ajogwu, Anthony Chidiebere Onyeozirila and Edwina Chinwe Onyeneke

    This review unravels the details of the immunological properties underlying the inducement, generation and control of immunological errors, the antigenic changes in the cells themselves, and the extent and activities of the immune response arising as a result of these changes.

    The immunological anomalies in humans which includes graft rejection, tissue transplantation, immunosuppression, immunoenhancement, malignant diseases, tumour immunology, hypersensitivity, immunopathology, immunodeficiency and autoimmune diseases were fully discussed as well as their immunological properties which will serve as a guide to immunological research activities and disease control.

    In this article, we reviewed the antigenic properties of the transformed cells and the ability of the host to mount an immune response to such antigens. Immunological errors itself can have effects on the immune system and these have to be taken into consideration in designing immunotherapeutic measures for the control of chronic and debilitating infectious diseases i.e. HIV is not a transforming virus and is therefore not directly responsible for the lymphomas and skin tumours found in AIDS patients.

    Keywords:

    Published on: Sep 19, 2018 Pages: 51-68

    Full Text PDF Full Text HTML DOI: 10.17352/2455-5479.000039
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