Open Access Case Report Article ID: GJA-1-103

    Severe Repeated Hypotension Occurred after Rocuronium Administrations in a Morbidly Obese Patient: A Case Report

    Fabio Silvio Mario Araimo Morselli*, Paolo Tordiglione, Ilaria Scarpa, Francesco Zuccarini, Giovanni Rosa

    Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2].

    Its pharmacokinetics and pharmacodynamics can be influenced by different factors as age, inhaled anesthetics, hepatic and renal insufficiency, hypothermia, gender and obesity [3-8].

    Rocuronium has been shown to cause less histamine release and cardiovascular instability than benzylisoquinolinum neuromuscular blocking agents such as atracurium and mivacurium [9], however it can act as an antigen: in our clinical experience three acute reactions occurred after its administration in the same patient.

    Keywords: Rocuronium; Hypotension; Severe obesity

    Published on: Sep 6, 2014 Pages: 13-15

    Full Text PDF Full Text HTML DOI: 10.17352/2455-3476.000003
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