Open Access Research Article Article ID: GJMCCR-4-139

    The Erosive Oral Lichen Planus Treatment with Nd:YAG Laser Combined with Total Glucosides of Paeony

    Lien Qi, Xing Wang* and Qian Deng

    Background: To investigate the clinical effect of Nd:YAG laser combined with total glucosides of paeony (TGP) for the treatment of erosive oral lichen planus (OLP). 

    Study Design: Sixty patients diagnosed with erosive OLP with clinical symptoms were divided into an observation group (n=28) and a control group (n=32) using a random number table. All erosive OLP patients received TGP while only the patients in observation group subjected to Nd:YAG laser. The clinical effects were evaluated comparatively three months before and after the treatment. 

    Results: Three months after the treatment, the visual analogue scales (VAS) score and sign score for observation group improved significantly to (1.36±0.89) points and (2.32±1.56) points respectively. The average VAS score and sign score for the control group were (2.75±1.67) and (3.66±1.33) points. In both groups, the results of treatments were tended to be significantly better than before (P<0.05). The average VAS score and sign score were superior to those in the control group (P<0.05). The effectiveness for the observation group was significantly higher than the control group (82.1% vs. 53.1%). 

    Conclusion: Nd:YAG laser combined with TGP can improve the efficiency of the treatment for erosive OLP. The scheme is safe and effective and worth expanding in clinical practice.

    Keywords: Nd:YAG laser; Oral lichen planus; Total glucosides of paeony; Erosive

    Published on: Mar 22, 2017 Pages: 25-27

    Full Text PDF Full Text HTML DOI: 10.17352/2455-5282.000039
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