Open Journal of Analytical and Bioanalytical Chemistry

    Abstract

    Open Access Research Article Article ID: OJABC-3-114

    Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Ibuprofen and Carisoprodol in Pharmaceutical Formulation

    A Lakshmana Rao* and P Vijetha

    A novel, rapid, precise and accurate stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Ibuprofen and Carisoprodol in combined pharmaceutical formulation. Chromatographic separation was achieved on Kromasil C18 column (250×4.6mm, 5μm) with UV detection at 260nm. The mobile phase consisting of 0.1% Ortho Phosphoric Acid (OPA) and acetonitrile in a ratio of 40:60v/v and adjusted the fl ow of mobile phase to 1.0mL/min.

    Keywords:

    Published on: Nov 6, 2019 Pages: 72-75

    Full Text PDF Full Text HTML DOI: 10.17352/ojabc.000014
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