A 83 year old Italian woman, with unremarkable family history, was admitted in 2013 to a Neurology Ward for lumbar pain and progressive motor impairment of right lower limb. The only remarkable event in her past history had been a clinical diagnosis of Rheumatoid Arthritis (RA) 20 years earlier, not confirmed by laboratory tests and radiological imaging. The neurological examination showed an isolated mild right lower limb paresis, 4/5 on the MRC scale (medical research council muscle scale), no sensory defi cit and preserved symmetrical tendon refl exes.
Brain MRI (magnetic resonance imaging) showed multiple patchy lesions, hyperintense on T2 and FLAIR, in the subcortical white matter and in the pons. CSF (cerebrospinal fluid) examination showed no abnormality and oligoclonal bands were absent. MRI of the spinal cord showed enlargement from D6 to D11. The ventral aspect was diffusely hyperintense on D2, with a nonhomogeneous enhancement. A transverse myelitis was hypothesized.
Published on: Jun 1, 2017 Pages: 23-24
University of Pisa, Italy
Annals of Psychiatry and Treatment
University of Nantes, France
Archives of Depression and Anxiety
Peter J Catalano
Tufts University, USA
Archives of Otolaryngology and Rhinology
Malgorzata Gabriela WASNIEWSKA
University of Messina, Italy
International Journal of Clinical Endocrinology and Metabolism
William CS Cho
Queen Elizabeth Hospital, Hong Kong
International Journal of Immunotherapy and Cancer Research