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Life Sciences Group

Studies on Stem Cells Research and Therapy

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Research Article PTZAID: SSCRT-2-107

A New Catheter Technology to Deliver Vascular Stem-Cells

Brian D Plourde, John R Stark and John P Abraham*

A new device has been designed, developed and tested to improve the capacity of vascular drug and stem cell delivery. The device consists of a catheter with a multitude of small lumens (instead of a large  central channel lumen). The use of multiple lumens provides a number of benefi ts to medical  intervention. First, the multiple lumens are spread across the catheter cross section. As a consequence,  the medication/stem cells are more effectively dispersed into the artery. Second, the construction of the new catheter has an increased mechanical strength compared to the standard single-lumen catheter – therefore, it is able to resist compressive forces caused by a pressurized balloon. This fact makes the new  design able to preserve medication/stem cell flowrates without causing mechanical hemolysis to the cells. Finally, the newly designed device prohibits clumping of stem cells carried in solution.

Published on: Dec 13, 2016 Pages: 7-16

Full Text PDF Full Text HTML DOI: 10.17352/sscrt.000007