Advertise with us
Clinical Group

Journal of Clinical Microbiology and Biochemical Technology



Abstract Open Access
Case Report PTZAID: JCMBT-2-107

Hepatopulmonary Syndrome and Portopulmonary Hypertension in the Same Patient

Glenda Ernst, Fernando Grassi and Julio F Chertcoff*

Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH) are the most common pulmonary vascular complications in patients with liver disease. We present a 71-year old woman with alcoholic cirrhosis and 6 month history of progressive shortness of breath with mild hypoxemia at rest. Results of spirometry was normal and diffusing capacity of the lung for carbon monoxide (DLCO) was severity reduced. Echocardiography with contrast enhancement revealed extra cardiac shunt. Three months after her initial presentation, a new echocardiography was performed with pulmonary systolic pressure increased and in a right heart catheterization (RHC) the mean pulmonary arterial pressure (PAPm) was 50 mmHg, this evidence supported the diagnosis of severe portopulmonary hypertension after HPS.

We consider that patients with HPS can develop POPH during the waiting time for liver transplant. Moderate and severe POPH represents a contraindication for liver transplantation because it could lead to an unacceptable mortality rate. Screening for POPH is relevant in patients while waiting for liver transplant.

Published on: Jan 29, 2016 Pages: 2-5

Full Text PDF Full Text HTML DOI: 10.17352/jcmbt.000007