Objective: This study was done to evaluate the maternal morbidities and perinatal outcomes of delivery in women with preterm pre-labor rupture of the membranes who delivered before and after 34 week along a period of five years in Al-Arish General Hospital.
Methods:This retrospective study involved pregnant women with a singleton pregnancy who suffered from preterm pre-labor rupture of the membranes. Maternal morbidities included chorioamnionitis and febrile reaction, umbilical cord prolapse, and puerperal pyrexia, while, neonatal outcomes comprised neonatal intensive care unit (NICU) admission as in case of neonatal sepsis or respiratory distress syndrome, neonatal jaundice, or eventual mortality.
Results: A total of 443 eligible women were involved. The mean age of included women was 23.11 ± 3.8 years (range: 18 – 38 years). The mean gestational age at delivery was 23.17 ± .2 weeks (range: 21 – 36 weeks). The included women were divided into 2 groups: group I n=232) including women who delivered at < 34 weeks of gestation; and group II (n=211) including women who delivered at ≥ 34 weeks of gestation. The rate of chorioamnionitis was significantly higher in women of group II [21 (9.95%) vs. 11 (4.74%), respectively, p=0.023].The rate of NICU admission for neonatal sepsis was significantly higher in women of group II [32 (15.2%) vs. 19 (8.2%)), respectively, p=0.018].
Conclusion: In case of PPROM, delivery after rather than before 34 weeks of gestation was linked to comparable rates of NICU admissions for neonatal RDS and jaundice with no statistically significant difference in perinatal mortality; yet with significantly higher rates of maternal morbidities as chorioamnionitis and neonatal sepsis.
Published on: Sep 13, 2016 Pages: 72-74