Pepper (chili or hot pepper) is one important plant for homology of food and medicine. At present, 1/4 people world worldwide are often taking peppers, also1/4 people world worldwide have allergic constitution. We observed many people who have allergic constitution are often taking peppers in the clinical. However, relation between often taking peppers and allergic constitution are unclear. In the present study, we examined the effects of peppers on immune system in rabbit that was administrated by peppers by means of intragastric administration q.d. for 3 months. Administration of peppers significantly increased contents of interleukin2(IL-2), IL-5, IL-16 , leukotriene D4(LTD4) , malonaldehyde (MDA) , bile acid (BA) and immune cells, especially eosinophile granulocyte (EO) and lymphocyte (LY) , significantly decreased activities of superoxide dismutase(SOD), in the serum of rabbits (respectively, P <0.05 or P <0.01 ). Our results indicate that often taking peppers could change body constitution to allergi constitution through induce individual immune dysfunction such as enhancement of IL-2, IL-5 , IL-16 , LTD4 ,BA ,EO and LY in the serum, increased free radicals; and suggest that regular consumption of peppers can become an independent cause of allergic constitution and has harmful actions to health.
Published on: Feb 14, 2017 Pages: 1-7