Aims: Prognosis of ethmoid sinus adenocarcinoma (ADK) is essentially determined by local tumor control. There is a high rate of recurrence of these tumors across the range of patient series. Development of an optimal follow-up protocol of such tumors is recommended.
Patients and methods: A retrospective, monocentric study was carried out including all patients diagnosed with ADK who underwent surgery and were followed up at our center between 2012 and 2016 and who were monitored postoperatively using magnetic resonance imaging (MRI) and histopathological verification of suspicious areas identified via imaging. Time to postoperative MRI, time to recurrence and sites of recurrence were obtained for each patient.
Objectives: Performance evaluation of MRI in early screening of recurrence or residual tumors post operatively in the management of ADK and identification of the main sites prone to risk of recurrence in these tumors.
Results: We included 24 cases of ADK, there were 33% cases of recurrence with a mean time to recurrence of 35 months postoperatively. Mean time to completion of the first MRI scan was 65 days postoperatively.
Performance parameters of screening for recurrence or residual tumors on the first postoperative MRI were:
Se 64%; Sp 78%; PPV 69%; NPV 74%.
Conclusions: Efficacy of postoperative MRI screening appears to be limited and regular endoscopic monitoring associated with imaging is required. Sites prone to risk should be subject to particular consideration in primary surgical resection and management of recurrence.
The benefit of imaging in the immediate postoperative period has yet to be assessed in terms of disease-free survival and disease control.
Published on: May 29, 2017 Pages: 51-55