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    Abstract

    Open Access Research Article PTZAID:GJIDCR-2-110

    Prevalence of Hepatitis B, Hepatitis C, HIV and Malaria Co Infection among Patients Infected with Visceral Leishmaniasis in Gedarif, Eastern Sudan

    Hashim B Mohammed, AbdelAziem A Ali, Mubarak I Idriss, Khalid M Gasmelseid, Mona M Yousif, Abdalazeem A Ibrahem and TajEldin M Abdallah*

    Background: Concomitant infections with HBV, HCV, HIV and Malaria among VL patients are not uncommon, thus this study conducted to describe the prevalence of HBV, HCV, HIV and Malaria co-infection with VL among patients admitted to Gedarif teaching hospital in Eastern Sudan.

    Methods: This was a retrospective, hospital-based study, carried out on data collected from the Medical records of confirmed VL patients at Gedarif Teaching Hospital between January 2013 and June 2014. Sera samples were tested for HBSAg, anti- HCV and HIV antibodies using enzyme-link immunosorbantassay (ELISA). Thick blood films were examined for malaria.

    Results: A total of 313 confirmed VL cases were enrolled in the study with mean age 31.4±(11.9) years. The majority of patients were male 237(75.7%). farmers 176 (56.2%) and rural residents 233(74.4%). Antibodies for HIV, HCV and HBV were detected in 14(4.4%), 5(1.6%) and 6(1.9%) cases respectively. Blood film positive for malaria was found in 29(9.1%). VL/HIV co-infection was noted in12 (3.8%) patients, VL/HBV co-infection was observed in 6(1.9%), VL/HCV co-infection was detected in four patients (1.3%), VL/ Malaria co-infection was accounted for 29(9.3%) and VL/HIV/HBV/HCV/ Malaria co-infection was identified in 6(1.9%). 27(8.5%) patients were died of whom 18(62, 1%) patients had VL/ Malaria co-infection and 2 (33.3%) patients had VL/HIV/HBV/HCV/ Malaria co-infection, 5(1.9%) patients had pure VL and 2(16.7%) had VL/HIV co- infection. Although there was no significant difference in age, Gender, residence, and occupation among different groups, there was a high proportion of deaths among VL/ Malaria co-infected cases 18(62.1%) vs. 5(1.9%) p=<.001.

    Conclusion: Concurrency of VL/HIV/HCV/HBV and Malaria is an existing entity in Eastern Sudan. Therefore, it is recommended to perform routine screening of VL infected patients for simultaneous infection with HIV, HBV, HCV and Malaria.

    Keywords:

    Published on: Oct 12, 2016 Pages: 21-24

    Full Text PDF Full Text HTML DOI: 10.17352/2455-5363.000010 CrossMark

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