Objective: Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to defi cient obese children from WV.
Design: Vit D defi cient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two supplement groups: 5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment.
Results: Sixty obese children were screened of whom 39 (65%) were defi cient (<20ng/ml). Of the 39 recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signifi cantly
higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml).
Conclusions: Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suffi cient to normalize 25(OH)D levels in Vit D defi cient obese West Virginian children.
Published on: Dec 8, 2016 Pages: 65-68
Peter Lloyd Nara
Private Compnay- Biological Mimetics, Inc., USA
Annals of Antivirals and Antiretrovirals
William CS Cho
Queen Elizabeth Hospital, Hong Kong
International Journal of Immunotherapy and Cancer Research
Sassari University, Italy
Archive of Urological Research
California South University, USA
Open Journal of Analytical and Bioanalytical Chemistry
Jose Manuel Ramia-Angel
Guadalajara University Hospital , Spain
Journal of Surgery and Surgical Research