Objective: Nasal septal deviation is a common disorder of the nose and patients commonly visit clinics with complaints of nasal obstruction. As a result of nasal obstruction, patients are exposed to snoring, which causes hypoxia. Hypoxia leads to chronic inflammation, oxidative stress and endothelial dysfunction. Platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) are new markers for inflammation. In this study we have aimed to study the relationship between hypoxia, PLR, NLR and other platelet markers in patients with septum and external deviations.
Methods: 100 patients (77 male, 23 female) with nasal obstruction, external nasal deformity and snoring symptoms, with severe septum deviations and external deviations were studied. The control group consisted of 101 (73 male, 28 female) people, making it in total 201 people in the study. Preoperative blood samples were taken from these subjects to look at the Hb (haemoglobin), Htc (haematocrit), RBC (the number of red blood cells), MCV (mean corpuscular volume), MCH (mean corpuscular haemoglobin), MCHC (mean corpuscular haemoglobin volume), MPV (mean platelet volume), neutrophils, lymphocytes PDW (platelet distribution ratio), PC (platelet count), PLR and NLR values.
Results: The PLR and NLR values were significantly higher in the control group compared with the female patient group. The PDW and MCH values were significantly higher in the male patient group compared with the control group.
Conclusion: We have shown that PLR and NLR values is a correlation in female patients with septum deviation. And we detected that PDW values were high in male patients with septum deviation. Patients with apparent septum deviation should be subject to surgery as soon as possible.
Published on: Jan 28, 2017 Pages: 17-21