Research Interest: Gentics; Tree Genetic
Improvement; Plant Biotechlology
Research Interest: Food Processing, health food and
cosmetics, Research of Chinese herbal medicine research, Agricultural
biotechnology, Supercritical fluid, and Mycology
Research Interest: Wheat genetic engineering for resistance to
Fusarium pathogens and tolerance to abiotic stresses, Molecular interaction
between wheat and Fusarium pathogens Recombinant antibodies and bio-agents
against Fusarium pathogens and mycotoxins
Research Interest: Phosphate-based glass production and characterisation including Phosphate glass-fibre (PGF) production. He is also currently working on resorbable polymer composites, mainly for bone repair applications. His other interests include, calcium phosphate cements, microsphere technologies, drug delivery systems, Tissue Engineering and Regenerative Medicine applications
Research Interest: Neurogenesis. Screening the leading chemical
to stimulate the neurogenesis after CNS, diseases, including: Stroke, Multiple
sclerosis, Alzheimers disease et al. Brain tumor. To study the oncogenesis
mechanisms of mellablastoma and glioblastoma.At the same time, to screen the
inhibitor of Sonic hedgehog pathway to treat the brain tumor.
Research Interest: Pharmacology/Toxicology Isolation
and Identification of Natural products, Drug Discovery and Development, Cellular
and Molecular Biology of Diseases
Research Interest: Polymer-based inorganic
nanocomposite, biomass composite materials
Research Interest: Studying the pathogenic process
in betanodavirus and iridovirus infection in grouper GF-1 and larval grouper
fish systems. His laboratory pioneered the use of grouper model to study
betanodavirus in vivo on brain damaged, which as a model.
Research Interest: Methodology of solid phase
peptide synthesis and synthetic peptides with bioactivity
Research Interest: Biological activity of blood
platelets; inflammatory properties of platelets; interaction of blood platelets
with the cells of the immune system; autoimmune diseases; activation and
platelet reactivity in neurodegenerative diseases (multiple sclerosis);
proteome, transcriptome and metabolome of platelets; molecular markers of
platelets in the diagnosis of acute coronary syndromes
Research Interest: pharmacological approaches in human ex vivo /
in vitro models targeted against inflammation&proliferation&migration
in atherosclerosis and restenosis following angioplasty.
Research Interest: Green materials processing, surface coating, nanomaterials, energy materials and biomaterials
Research Interest: Fungal biotechnology, Marine bacterial
phylogenetics and taxonomy
Research Interest: Regulation of extracellular matrix genes and growth factors by potential anti-skin aging, anti-carcinogenic or wound repair agents in normal or cancer cells:Area of Expertise: Biochemistry and Cell/Molecular Biology; Biotechnology: Cell culture, Gene Regulation (protein, mRNA, promoter levels), Extracellular matrix (collagen, matrixmetalloproteinases, elastin, fibrillin), Growth factors/cytokines (tranaforming growth factor-b, interleukins), Oxidative Stress/Reactive Oxygen species, Antioxidants, Apoptosis, Toxicity, Angiogenesis/Metastasis.
Research Interest: Polymeric Biomaterials and Green Materials: -Synthesis and Characterization, Surface Modification, and Patterning (soft and dip-pen lithography) and Polymers processing, Synthesis of Polyurethanes/Polyesters and Bio-based resins. Nanomaterials and Energy Materials: Polymer-HA or Polymer-CNT Nanocomposites, Synthesis of Nanofibers and Nanoparticles for cancer drug delivery, Chemical modification of Nanodiamond particles and Metallization of CNTs, Polymeric and silica Nanorods as reinforcing fillers for dental restoration materials for flowable composites), Polymer/graphene composite materials and Polymer/polyoxometalate composites for energy applications. Tissue Engineering/ Drug Delivery: Polymeric 3D-Nanofibrous Scaffolds for Bone, Vascular, Neural and Dental, Salivary glands and multifunctional nanoparticles for lung cancer drug and growth factor delivery, Nasal/mucosal delivery of therapeutics), Electrospining and Force-spinning techniques for polymer and ceramic composite nanofabrication. Additive bio-manufacturing and We-laid Process for biomaterials/scaffolds of complex tissues and interfaces. Characterization of Materials: Microscopic and Spectroscopic characterization (SEM, AFM, FT-IR, XPS), mechanical properties characterization (Tensile, compression, dynamic mechanical (DMA) and nanoindentation), thermal properties (TGA, DSC, TMA) and Rheological characterization of polymeric biomaterials, nanomaterials and hybrid polymer/inorganic composites and in vitro Cell Studies for biocompatibility and toxicity. In Vitro Evaluation of nano-structured materials/ nanodiamond wear-debris from orthopedic joint implants: Nanoscaled wear-debris isolation from Hip and knee Simulator (AMTI) and its inflammatory effect evaluation.
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Manuel Jose Lis Arias
Polytechnic University of Catalonia, Spain
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