Prof. Pierre Guertin
Laval University, Canada
Tel: +1 418-525-4444, pos
Fax: +1 418-654-2753
Research Interest: Isolation and structure elucidation of natural products, Search for bioactive compounds, Antifungal, Anticancer and anti-inflammatory phytochemicals from traditional Chinese medicine (TCM) or other ethnic medicine (e.g. Tujia, Miao and so on);Chemical and pharmacological study of Chinese medicine; Quality control study of Chinese medicine.
Role of Cannabinoid, Vanilloid and kappa-opioid receptors in the gastrointestinal
tract, both in physiological (e.g. intestinal motility) and pathophysiological
states (e.g. inflammation and cancer); Ethnopharmacological studies on
medicinal plants and their active ingredients used in traditional medicine; Clinical pharmacology
of herbal products; Nutritional pharmacology.
Research Interest: Targeting drug delivery systems (TDDS), Multifunctional nanocarriers or macromolecules have many advantages for diseases treatments. Our lab employs diverse targeting delivery systems including conjugate, liposomes and micelles to deliver anticancer drug or gene for tumor therapy. In this process, we unitize stimuli-responsive strategies (e.g. enzyme-responsive) to obtain the targeting therapy of tumor. Cell-penetrating peptides (CPPs) are also adopted to cross cellular barriers. Internalization mechinisms of CPPs or CPP-cargoes are also focused by us.
Research Interest: Design, Synthesis and qualitative SAR of new anticonvulsant agents acting as non-competitive AMPA receptor antagonists (In collaboration with Dr. Li Niu, Chemistry Department, University at Albany, SUNY, Albany NY), Identifications and synthesis of new anti-cancer agents, Design and synthesis of peptidomimetics as protease inhibitors.
Research Interest: Medicinal chemistry, Structure-activity relationship studies, Synthesis of heterocyclic compounds, Antimicrobial screening, Enzymatic studies.
Research Interest: Immunogenicity, PK, Biomarker, Regulated and non regulated bioanalysis.
Research Interest: G-protein coupled receptors for lipid mediators, Molecular and cellular functions of lipid mediators.
Research Interest: Pharmaceutics, Pharmaceutical Sciences, Drugdelivery, Inhalation, Dosage forms, Particle engineering.
Research Interest: Separation & purification and quality control of food science; new functional materials for food and pharmaceutical analysis.
Research Interest: Effects of different diets, Dietary factors and fatty acids (especially conjugated fatty acids) on health, Especially on the Cancer Risk.
Research Interest: Organic Chemistry: Total Synthesis of Complex Natural Product, Computational Chemistry: Conformational Analysis, Molecular Modelling and Spectra Simulation. Natural Product Discovery: Isolation, Structural Elucidation, and Absolute Configuration Deter-mination of Natural Product.
Research Interest: Microbiology and Immunology, Antibiotic mechanism of Action and resistance, Inflammation and Natural Antiinflamatory Products.
Research Interest: Cancer Diagnostics, Cancer Research, Clinical Trials, Ophthalmology, Business, Economic Genetics, Stem Cell Biology, Cell Biology, Translational Cancer Research, Business Ethics, Oncology, Molecular Biology.
Research Interest: Ophthalmology, Cataract Surger,Cornea, Refractive Eye Surgery, Keratoconus.
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Published On: November 24, 2017 | Pages: 036 - 038Abstract View Full Article View
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