Research Interest: bacteriology, mycobacterium tuberculosis, and especially anaerobic bacteria

Research Interest: Cancer/stem cell biology, Apoptosis related signaling mechanisms and differentiation, cytokines receptors and immunoregulation , Proteomics Research techniques; Molecular Biology Techniques (Cell Culture, Gene Transduction/Transfection, Immunofluoresance, Immunoblotting etc), Cloning, 2D-PAGE, Quantitative-PCR, Flow cytometry, Animal tumor models.

Research Interest: ENVIRONMENTAL MONITORING and MARINE MICROBIOLOGY Marine microbiology and microbial ecology Set up and application of new rapid methods for the assessment of the microbiological quality of marine and brackish waters,

Research Interest: Transcriptional regulation during germinal center formation (GC B, Tfh/Tfr differentiation controlled by TFs such as Bcl6, Bach2, etc.); Transcriptional control of immune disorders

Grants:
1. National Natural Science Foundation of China (NSFC Grant #: 31800755 to C.P.)
2. Start-up Funding for Young Teachers (Shanghai Jiao Tong Univ. Grant #: KJ30214160111 to C.P.)

PUBLICATIONS:
Papers in Refereed Journals:
1. Cheng Peng, Qianwen Hu, Fang Yang, Heng Zhang, Fubin Li, Chuanxin Huang. 2019. Bcl6-mediated silencing of PD-1 ligands in germinal center B-cells maintains follicular T cell population. The Journal of Immunology 202 (3): 704-713.

2. Siyu Deng, Qianwen Hu, Heng Zhang, Fang Yang, Cheng Peng*, Chuanxin Huang. 2019. HDAC3 inhibition up-regulates PD-L1 expression in B-cell lymphomas and augments the efficacy of anti-PD-L1 therapy. Molecular Cancer Therapeutics. (DOI: 10.1158/1535-7163) (*co-corresponding)

3. Qilin Zhang, Cheng Peng*, Jianping Song, et al. 2017. Germline Mutations in CDH23, Encoding Cadherin-Related 23, Are Associated with Both Familial and Sporadic Pituitary Adenomas. The American Journal of Human Genetics 100 (5): 817-823. (*co-first)

4. Cheng Peng and Laurel A. Eckhardt. 2013. Role of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition. The Journal of Immunology 191 (8): 4399-4411.

5. Siyu Deng, Cheng Peng, Chuanxin Huang. 2019. Studies on the molecular mechanisms of HDACi mediated CD47 upregulation in B cell lymphoma (HDACi诱导B细胞淋巴瘤表达CD47分子机制研究). Current Immunology (现代免疫学) 39 (1): 12-17.

6. Hong Peng, Fang Yang, Qianwen Hu, Jian Sun, Heng Zhang, Cheng Peng, Yao Zhao, Chuanxin Huang. 2019. The ubiquitin-specific protease USP8 directly deubiquitinates p62/SQSTM1 to suppress its autophagic activity. Autophagy. (in press)

7. Heng Zhang, Qianwen Hu, Min Zhang, Fang Yang, Cheng Peng, Xiaobo Liu, Fubin Li, Zhen Zhang, Nan Shen, Ari Melnick, Chuanxin Huang. 2019. Bach2 deficiency in T cells drives the accumulation of pathogenic Tfh cells and humoral autoimmunity. (submitted)

8. Jianhua Chen, Xuemin Jian, Siyu Deng, Zengyi Ma, Xuefei Shou, Yue Shen, Qilin Zhang, Zhijian Song, Zhiqiang Li, Hong Peng, Cheng Peng, Min Chen, Cheng Luo, Dan Zhao, Zhao Ye, Ming Shen, Yichao Zhang,Juan Zhou, Aamir Fahira, Yongfei Wang, Shiqi Li, Zhaoyun Zhang, Hongying Ye, Yiming Li, Jiawei Shen,Hong Chen, Feng Tang, Zhenwei Yao, Zhifeng Shi, Chunjui Chen, Lu Xie, Ye Wang, Chaowei Fu, Ying Mao,Liangfu Zhou, Daming Gao, Hai Yan, Yao Zhao, Chuanxin Huang and Yongyong Shi. 2018. Identification of recurrent USP48 and BRAF mutations in Cushing’s disease. Nature Communications 9 (1): 3171.

9. Jian Sun, Qianwen Hu, Hong Peng, Cheng Peng, Liheng Zhou, Jinsong Lu, Chuanxin Huang. 2018. The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43. The Journal of Biological Chemistry 293 (21): 8275-8284.

10. Ye Hong, Lei Wu, Bo Liu, Cheng Peng, Duohong Sheng, Jinfeng Ni, Yulong Shen. 2007. Characterization of a glucan phosphorylase from the thermophilic archaeon Sulfolobus tokodaii strain 7. Journal of Molecular Catalysis B: Enzymatic 54 (1-2): 27-34.

Research Interest: Biochemistry :Eand the impact of oxidative stress on DNA and proteins. Nicotine and xilose metabolism in bacteria. purification and kinetic characteristic of various oxidoreductases Molecular Biology: Gene cloning and amplification. Recombinant proteins techniques

Bioinformatics: Protein structure prediction and modeling. In-silic

Research Interest: Blood Glucose, Diabetes, Rats, Antioxidants, Oxidative Stress, Malondialdehyde, Diabetes Mellitus, Rat Models, Nitric Oxide Synthase 

Dr. Pongsak Rattanachaikunsopon is a Professor in the Department of Biological Science at University of Ubon Ratchathani, Thailand. He obtained Bachelor of Science in Radiological Technology at Mahidol University, Thailand and a Master of Science in Anatomy at Mahidol University, Thailand. He earned Ph.D. in Molecular Biology at Lehigh University, Pennsylvania USA. He has been awarded with Professor Sood Saengvichain Award for Best Research and Presentation in 13th Annual Meeting of the Society of Anatomy of Thailand in 1990, Professor Dr. Tab Nilanidhi Foundation Award for the outstanding graduate student in Anatomy in 1991 and Best Government Officer, The Ministry of Education in 2014. He serves as an Editorial board member of more than 10 international Journals.

Research of interest

Prof. Dr. Pongsak Rattanachaikunsopon is interested fields of research are Molecular Biology, Microbiology and Biochemistry. His present research focuses on searching for biological agents such as microorganisms and plants to use as alternatives to control animal and human diseases caused by pathogenic bacteria.

PUBLICATIONS

International Publications

1. Rattanachaikunsopon P, Sudwan P, Chunhabundit P, Bamroongwong S, Somana R: Thyroid microvasculature in common tree shrew (Tupaia glis) as revealed by corrosion cast technique and studied with SEM.  Acta Anatomica 1991; 142: 208-214.

2. Sudwan P, Chunhabundit P, Bamroongwong S, Rattanachaikunsopon P, Somana R: Hypophyseal angioarchitecture of common tree shrew (Tupaia glis) revealed by scanning electron microscopy of vascular corrosion casts.  The American Journal of Anatomy 1991; 192: 262-273.

3. Bamroongwong S, Somana R, Rojananeungnit S, Chunhabundit P, Rattanachaikunsopon P:  Scanning electron microscopic study of the splenic vascular casts of common tree shrew (Tupaia glis).  Anatomy and Embryology 1991; 184 (3): 301-304.

4. Bamroongwong S Chunhabundit P, Rattanachaikunsopon P, Somana R:  Pancreatic  microcirculation in the common tree shrew  (Tupaia glis) as revealed by scanning electron microscopy of corrosion casts.  Acta Anatomica 1992; 143: 184-188.

5. Rattanachaikunsopon P, Rosch C, Kuchka M: Cloning and characterization of the nuclear AC115 gene of Chlamydomonas reinhardtii. Plant Molecular Biology 1999; 39 (1): 1-10.

6. Rattanachaikunsopon P, Phumkhachorn P: Lactic acid bacteria isolated from Thai fermented foods and their antibacterial activity. ASEAN Journal on Science and Technology for Development 1999, 16(2): 19-29.

7. Rattanachaikunsopon P, Phumkhachorn P : A bacteriocin produced by Lactobacillus lactis subsp. lactis isolated from Thai fermented foods. ScienceAsia 2000; 26(4): 195-200.

8. Rattanachaikunsopon P, Phumkhachorn P: Isolation and preliminary characterization of a bacteriocin produced by Lactobacillus plantarumN014 isolated from nham, a traditional Thai fermented pork. Journal of Food Protection 2006, 69(8): 1937-1943.

9. Phumkhachorn P, Rattanachaikunsopon P, Khunsook S: The use of gfp gene in monitoring bacteriocin-producing Lactobacillus plantarum N014, a potential starter culture in nham fermentation. Journal of Food Protection 2007, 70(2): 419-424.

10. Rattanachaikunsopon P, Phumkhachorn P: Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens. Fitoterapia 2007, 78(6): 434-436.

11. Rattanachaikunsopon P, Phumkhachorn P: Incidence of nisin Z production in Lactococcus lactis subsp. lactis TFF 221 isolated from Thai fermented foods. Journal of Food Protection 2008, 71(10): 2024-2026.

12. Rattanachaikunsopon P, Phumkhachorn P: Characterization of nisin produced by Lactococcus lactis RP359 isolated from Kem-Buk-Nud, a traditional Thai fermented food. The Internet Journal of Microbiology 2008, 5(1).

13. Rattanachaikunsopon P, Phumkhachorn P: Diallyl sulfides content and antimicrobial activity against foodborne pathogenic bacteria of chives (Allium schoenoprasum). Bioscience, Biotechnology and Biochemistry 2008, 72(11): 2987-2991.

14. Pachanawan A, Phumkhachorn P, Rattanachaikunsopon P: Potential of Psidium guajava supplemented fish diets in controlling Aeromonas hydrophila infection in tilapia (Oreochromis niloticus). Journal of Biotechnology and Bioengineering 2008, 106(5): 419-422.

15. Rattanachaikunsopon P, Phumkhachorn P: Prophylactic effect of Andrographis paniculata extracts against Streptococcus agalactiae infection in Nile tilapia (Oreochromis niloticus). Journal of Biotechnology and Bioengineering 2009, 107(5): 579-582.

16. Rattanachaikunsopon P, Phumkhachorn P: Antimicrobial activity of elephant garlic oil against Vibrio cholerae both in vitro and in food model. Bioscience, Biotechnology and Biochemistry 2009, 73(7): 623-627.

17. Rattanachaikunsopon P, Phumkhachorn P: Glass bead transformation method for Gram-positive bacteria. Brazilian Journal of Microbiology 2009, 40: 923-926.

18. Rattanachaikunsopon P, Phumkhachorn P: Protective effects of clove oil supplemented fish diets on experimental Lactococcus garvieae infection in tilapia. Bioscience, Biotechnology and Biochemistry 2009, 73(9): 2085-2089.

19. Rattanachaikunsopon P, Phumkhachorn P: Glass bead-based transformation method for lactic acid bacteria. ScienceAsia 2009, 35:234-241.

20. Rattanachaikunsopon P, Phumkhachorn P: Potential of Chinese chive oil as a natural antimicrobial for controlling Flavobacterium columnare infection in Nile tilapia Oreochromis niloticus. Fisheries Science 2009, 75:1431-1437.

21. Rattanachaikunsopon P, Phumkhachorn P: Shallot (Allium ascalonicum L.) oil: diallyl sulfide content and antimicrobial activity against food-borne pathogenic bacteria. African Journal of Microbiology Research 2009, 3:747-750.

22. Rattanachaikunsopon P, Phumkhachorn P: In vitro study of synergistic antimicrobial effect of carvacrol and cymene on drug resistant Salmonella typhi. African Journal of Microbiology Research 2009, 3:978-980.

23. Rattanachaikunsopon P, Phumkhachorn P: Use of Centella asiatica aqueous extract as bath treatment to control columnaris in tilapia (Oreochromis niloticus). Journal of Aquatic Animal Health 2010, 22:14-20.

24. Rattanachaikunsopon P, Phumkhachorn P: Potential of coriander (Coriandrum sativum) oil as a natural antimicrobial in inhibiting Campylobacter jejuni in raw meat. Bioscience, Biotechnology and Biochemistry 2010, 74:31-35.

25. Rattanachaikunsopon P, Phumkhachorn P: Synergistic antimicrobial effect of nisin and ρ-cymene against Salmonella enterica serovar Typhi in vitro and on ready-to-eat food. Bioscience, Biotechnology and Biochemistry 2010, 74:520-524.

26. Rattanachaikunsopon P, Phumkhachorn P: Potential of cinnamon (Cinnamomum verum) oil in controlling Streptococcus iniae infection in tilpia (Oreochromis niloticus). Fisheries Science 2010, 76:287-293.

27. Rattanachaikunsopon P, Phumkhachorn P: Contents and antibacterial activity of flavonoids extracted from leaves of Psidium guajava. Journal of Medicinal Plants Research 2010, 4:393-396.

28. Rattanachaikunsopon P, Phumkhachorn P: Assessment of synergistic efficacy of carvacrol and cymene against Edwardsiella tarda in vitro and in tilapia (Oreochromis niloticus). African Journal of Microbiology Research 2010, 4:420-425.

29. Thamniamton W, Boonsarn V, Phumkhachorn P, Rattanachaikunsopon P: Isolation and characterization of a bacteriophage specific to drug resistant Klebsiella pneumoniae DR1. International Journal of Current Research and Review 2010, 2 (4):30-43.

30. Rattanachaikunsopon P, Phumkhachorn P: Effect of Cratoxylum formosum on innate immune response and disease resistance against Streptococcus agalactiae in tilapia Oreochromis niloticus. Fisheries Science 2010, 76:653-659.

31. Rattanachaikunsopon P, Phumkhachorn P: Antimicrobial activity of basil (Ocimum basilicum) oil against Salmonella Enteritidis in vitro and in food. Bioscience, Biotechnology and Biochemistry 2010, 74:1200-1204.

32. Phumkhachorn P, Rattanachaikunsopon P: Isolation and partial characterization of a bacteriophage infecting the shrimp pathogen Vibrio harveyi. African Journal of Microbiology Research 2010, 4:1794-1800.

33. Rattanachaikunsopon P, Phumkhachorn P: Assessment of factors influencing antimicrobial activity of carvacrol and cymene against Vibrio cholerae in food. Journal of Bioscience and Bioengineering 2010, 110:614-619.

34. Rattanachaikunsopon P, Phumkhachorn P: Lactic acid bacteria: their antimicrobial compounds and their uses in food production. Annals of Biological Research 2010, 1:218-228.

35. Rattanachaikunsopon P, Phumkhachorn P: Bacteriophages: Discovery and therapeutic uses in humans and animals. International Journal of Current Research and Review 2010, 2 (11):3-8.

36. Phumkhachorn P, Rattanachaikunsopon P: Bacteriophage specific to nisin producing-Lactococcus lactissubsp. Lactis TFF221, a starter culture in Thai fermented food. African Journal of Microbiology Research 2011, 5(6): 1203-1210.

37. Rattanachaikunsopon P, Phumkhachorn P: Detection of Aeromonas salmonicida by reverse transcription-multiplex polymerase chain reaction. Bioscience, Biotechnology and Biochemistry 2012, 76(4): 665-670.

38. Rattanachaikunsopon P, Phumkhachorn P: Identification of viable Listeria species based on reverse transcription-multiplex PCR (RT-PCR) and restriction digestion. Bioscience, Biotechnology and Biochemistry 2012, 76(6): 1189-1194.

39. Rattanachaikunsopon P, Phumkhachorn P: Construction of food-grade cloning vector for Lactobacillus plantarum and its utilization in food model. Journal of General and Applied Microbiology 2012, 58(4): 317-324.

40. Phumkhachorn P, Rattanachaikunsopon P: Isolation and characterization of lytic phage against Lactococcus lactisRP359, kem-buk-nud starter culture. African Journal of Microbiology Research 2012, 6(37): 6678-6684.

41. Surapat W, Pukahuta C, Rattanachaikunsopon P, Aimi T, Boonlue S: Characterization of phosphate solubilization by phosphate-solubilizing bacteria isolated from agricultural chili soil and their efficiency on the growth of chili (Capsicum frutescens L. cv. Hua Rua). Chiang Mai Journal of Science 2013, 40(1): 11-25.

42. Butprom S, Phumkhachorn P, Rattanachaikunsopon P: Effect of Lactobacillus plantarum C014 on innate immune response and disease resistance against Aeromonas hydrophila in hybrid catfish. The Scientific World Journal 2013, 2013:1-6.

43. Rattanachaikunsopon P, Phumkhachorn P: Bacteriophage ϕLPN014 infecting Lactobacillus plantarum N014, a potential starter culture for NHAM fermentation. Annals of Experimental Biology 2014, 2(1):1-7.

44. Somnate T, Phumkhachorn P, Rattanachaikunsopon P: Potentail of virulent bacteriophage as a biocontrol agent against Salmonella Typhimurium in beverages. Journal of Pure and Applied Microbiology 2014, 8(2):1131-1139.

45. Phumkhachorn P, Rattanachaikunsopon P: A lytic bacteriophage with potential for inactivation of a fish pathogenic Streptococcus agalactiae. Journal of Pure and Applied Microbiology 2014, 8(Spl. Edn. 2):371-379.

46. Punyauppa-path S, Phumkhachorn P, Rattanachaikunsopon P: Nisin: Production and mechanism of action. International Journal of Current Research and Reviews 2015, 7(2): 47-53.

47. Phumkhachorn P, Rattanachaikunsopon P: Therapeutic use of Cassia alata aqueous extract as bath treatment to control Pseudomonas anguilliseptica infection in tilapia (Oreochromis niloticus). Archives of Biological Sciences 2015, 67(4): 1165-1172.

48. Punyauppa-path S, Phumkhachorn P, Rattanachaikunsopon P: Factors influencing synergistic antimicrobial activity of thymol and nisin against Shigella spp. in sugarcane juice. Biologia 2015, 7(8): 1003-1010.

49. Phumkhachorn P, Rattanachaikunsopon P: A Siphoviridae bacteriophage specific to Extended-spectrum b-lactamases-producing Escherichia coli. Journal of Chemical and Pharmaceutical Research 2015, 7(11): 604-608.

50. Panya M, Lulitanond V, Rattanachaikunsopon P, Srivoramas T, Chaiwong T: Isolation, Identification and Evaluation of Novel Probiotic Strains isolated from Feces of Breast-Fed Infant. Journal of the Medical Association of Thailand 2016, 99 Suppl 1: S28-S34.

51. Phumkhachorn P, Rattanachaikunsopon P: A broad host range food-grade cloning vector for lactic acid bacteria. Biologia 2016, 71(5): 457-463.

52. Phumkhachorn P, Rattanachaikunsopon P: Detection of viable Salmonella Typhi using three primer pairs specific to invA, ivaB and fliC-d genes. Emirates Journal of Food and Agriculture 2017, 29(4): 312-316.

53. Rattanachaikunsopon P, Phumkhachorn P. Bacteriophages as Future Prophylactic and Therapeutic Agents against Foodborne Bacterial Pathogens. International Journal of Nutrition and Health Sciences 2017, 2(1): 19-20.

54. Rattanaborvorn W., Phumkhachorn P, Rattanachaikunsopon P: Potential of Bacteriophages in Controlling Drug Resistant Shigella sonnei. Asian Journal of Microbiology, Biotechnology and Environmental Science 2017, 19(3): 1-5.

55. Phumkhachorn P, Rattanachaikunsopon P: Bacteriophage therapy as a future preventive and curative approach against bacterial infections in aquaculture. Multidisciplinary Advances in Veterinary Science 2017,

Research Interest: Mellitus, Rat Models, Nitric Oxide Synthase 

Research Interest: Biochemistry. Nanotechnology in Drug Delivery. Molecular Biology. Molecular Virology. Cancer Biology. Tissue Culture and Stem Cell Therapy

Biography: "Wallace Felipe Blohem Pessoa is a graduate of Biomedical Sciences from the State University of Santa Cruz (UESC), Ilhéus, BA, Brazil in 2012. Dr. Blohem received his Msc Degree in Microbiology and Biotechnology from State University of Santa Cruz, Ilhéus, BA, Brazil in 2014 and his PhD degree in Microbiology and Biotechnology from the same University in 2018. Currently, he is an Adjunct Professor in Science and Technology College (FTC), Itabuna, BA, Brazil. He has special interest in the research on probiotics (specially Lactobacillus), microbial antagonism, hospital infection and venomics."

Research Interest: Cell Biology, Histology, Histopathology, Immunocytochemistry, Electron Microscope

Research Interest: His research interests include Chronic Hepatitis, Febrile neutropenia and Infection surveillance and 

Research Interest: Microbiology, Biochemistry, Molecular biology, Biotechnology  Bacterial pathogens from human and animal origin and their molecular mechanisms involved in pathogenisis and virulence. Study of antimicrobial resistance and mechanisms of resistance.

Research Interest: His research interests include Chronic Hepatitis, Febrile neutropenia and Infection surveillance and control programs