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Medical Group

Annals of Antivirals and Antiretrovirals

Castalagin: Some aspects of the mode of Anti-Herpes Virus Activity

Published On: February 15, 2018 | Pages: 004 - 007

Author(s): N Vilhelmova-Ilieva, D Deffieux, S Quideau, AS Galabov*
Castalagin, a nonahydroxytriphenoyl-bearing C-glucosidic ellagitannin, manifested a marked virucidal effect on HSV-1. ...
Abstract View Full Article View DOI: 10.17352/aaa.000004

Thiolutin Derivatives as inhibitor of RNA-Dependent RNA Polymerase (RdRP) of Hepatitis C Virus: An In-silico Approach

Published On: January 17, 2018 | Pages: 001 - 003

Author(s): Muhammad Imran Qadir*, Asma Munawar, Syed Bilal Hussain
Docking study of few Thiolutin derivatives, which originally act as Hepatitis C Virus RNA Dependent RNA Polymerase (RdRP) inhibitor, was performed by using AutoDock Vina. The docking studies reveal that thiolutin interacted with Hepatitis C Virus RNA Dependent RNA Polymerase through hydrogen bonding as well as hydrophobic interactions. Its binding energy after modific ...
Abstract View Full Article View DOI: 10.17352/aaa.000003