Research Interest: 1. biologia Geral, 2. Genética, 3. Fisiologia de Órgãos e Sistemas, 4.
Research Interest: Toxicology；Pharmacology；Natural product; Biochemistry；Pathology；Cell singing pathway; Ethnobotanical medication and food.
Research Interest: Neurofibrillary tangles composed of hyperphosphorylated tau protein accumulate in the Alzheimer’s disease and in other Neurodegenerative disease
Research Interest: CNS lymphomas, immunodeficiency associated lymphoproliferative disorders, therapy associated myeloid neoplasms and acute myeloid leukemia.
I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.
Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells
List of Publication:
Research Interest: Microbiology, Infectious diseases, Antimicrobial resistance.
Research Interest: Mechanistic toxicology of carcinogenic/neurotoxic substances, occupational/environmental toxicants, & gene therapy for management • Reproductive toxicology with regard to intra-spermatozoal signaling associated to occupational/environmental toxicants.
Research Interest: Medicinal plants valorization, Natural compounds’ action mechanism elucidation, Chemical-biology, Tumoral hepatic microenvironment, Infectious diseases.
Research Interest: Stem cell, cancer stem cell, immuno cell therapy, angiogenesis.
Research Interest: Extracellular matrix, glycosaminoglycans, hyaluronan, Inflammation – experimental models, Free radicals – oxidants and antioxidants, NF-kB pathway and cytokines, TLRs and innate immunity.
Research Interest: 1. Primary rat astroglial cells cultures. 2. Neuroblastoma and glioblastoma cells cultures. 3. Effect of antioxidant molecules [(+) thioctic acid, (+/-) thioctic acid] and choline containing compounds on proliferation and differentiation neural cell culture. 4. Study of anticancer molecules (e.g. bortezomib) and neuroprotective ones (e.g. thioctic acid) in in vitro model of neoplastic cell cultures. 5. Effect of alpha lipoic acid and choline-containing compounds, on the expression of some astroglial biomarkers during proliferation and differentiation of astrocyte cell cultures and neuroblastoma cell lines.
Research Interest: • Pathophysiology and molecular immunology applied to immunological research lines.• Molecular processes underlying the interaction between receptors of the immune response, inflammation and characterization of new anti-inflammatory molecules. • Novel therapies for Sjögren’s syndrome autoimmune disease. • Evaluation of the pathogenic role of autoantibodies produced in the course of autoimmune diseases. e.t.c,
Research Interest: Calcium signaling, next-generation sequencing, genetical disease, cancer stem cell. Thank you very much.
Research Interest: Lung and breast translational research, Toward personalized medicine of lung cancer: response to nontargeted therapy in invasive pulmonary adenocarcinoma as a function of tumor cell differentiation, Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma not otherwise specified) of the breast: clinicopathologic study of 19 cases, Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases, Del(5q) is associated with clinical and histological parameters in small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series.
Research Interest: Oral cancer and molecular biomarkers of Head and Neck tumors
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Published On: January 28, 2016 | Pages: 005 - 017Abstract View Full Article View Get Citation Base Search Scilit OAI-PMH ResearchGate SciForum
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Hon. Pierre Guertin
Laval University, Canada
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