ISSN: 2692-4595 Open Access Annals of Molecular and Genetic Medicine

Annals of Molecular and Genetic Medicine

    Introduction

    • Volume/IssueClick here
    • Review ProcessDouble Blind
      • Publication lead time3 - 4 weeks
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    • Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles.
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    Executive Editors

    Wei Wu
    Associate Professor
    School of Public Health
    Nanjing Medical University
    China
    epigenetic@126.com
    AMGM

    Research Interest: Environmental, genetic and epigenetic risk factors on human reproductive and developmental health; Gene-environment interactions in reproductive & endocrine systems;  Representative EDCs reproductive endocrine toxicity and its mechanism.

    Number of publications: 61 

    List of Publications:

    1. Yuan B, Wu W*, Chen M, Gu H, Tang Q, Guo D, Chen T, Chen Y, Lu C, Song L, Xia Y, Chen D, Rehan V, Sha J, Wang X*. Metabolomics reveals a role of betaine in prenatal DBP exposure-induced epigenetic transgenerational failure of spermatogenesis in rats. Toxicol Sci. 2017; 158 (2): 356-366. (Cover Article)

    2. Tang Q, Chen Y, Wu W*, Ding H, Xia Y, Chen D, Wang X. Idiopathic male infertility and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking. Sci Rep. 2017; 7(1):11219. 

    3. Wang L, Hu W, Guan Q, Du G, Chen T, Wu W, Wang Y, Wang X, Xia Y. The association between cooking oil fume exposure during pregnancy and birth weight: A prospective mother-child cohort study. Sci Total Environ. 2017; 612:822-830.

    4. Qiao S, Wu W (co-first author), Chen M, Tang Q, Xia Y, Jia W, Wang X. Seminal plasma metabolomics approach for the diagnosis of unexplained male infertility. PLoS One. 2017; 12(8):e0181115. 

    5. Hu W, Chen M, Ji J, Qin Y, Zhang F, Xu M, Wu W, Du G, Wu D, Han X, Jin L, Xia Y, Lu C, Wang X. Interaction between Y chromosome haplogroup O3* and 4-n-octylphenol exposure reduces the susceptibility to spermatogenic impairment in Han Chinese. Ecotoxicol Environ Saf. 2017; 144:450-455.

    6. Pan L, Liu Q, Li J, Wu W, Wang X, Zhao D, Ma J. Association of the VDAC3 gene polymorphism with sperm count in Han-Chinese population with idiopathic male infertility. Oncotarget. 2017; doi: 10.18632/oncotarget.16891. 

    7. Chang C, Chen M, Gao J, Luo J, Wu K, Dong T, Zhou K, He X, Hu W, Wu W, Lu C, Hang B, Meeker JD, Wang X, Xia Y. Current pesticide profiles in blood serum of adults in Jiangsu Province of China and a comparison with other countries. Environ Int. 2017; 102:213-222.

    8. Gu H, Wu W*, Yuan B, Tang Q, Guo D, Chen Y, Xia Y, Hu L, Chen D, Sha J, Wang X. Genistein up-regulates miR-20a to disrupt spermatogenesis via targeting Limk1. Oncotarget. 2017; 8(35):58728-58737. 

    9. Guo D, Wu W*, Tang Q, Qiao S, Chen Y, Chen M, Teng M, Lu C, Ding H, Xia Y, Hu L, Chen D, Sha J, Wang X. The impact of BMI on sperm parameters and the metabolite changes of seminal plasma concomitantly. Oncotarget. 2017; doi: 10.18632/oncotarget.14950.

    10. Chen T, Xu J, Liu G, Liu H, Chen M, Qin Y, Wu W, Xia Y, Ji C, Guo X, Wen J, Wang X. Genetic variants in PTPRD and risk of gestational diabetes mellitus. Oncotarget. 2016; 7(46):76101-76107.

    11. Ji J, Qin Y, Zhou R, Zang R, Huang Z, Zhang Y, Chen M, Wu W, Song L, Ling X, Shen H, Hu Z, Xia Y, Lu C, Wang X. X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in han chinese population. Oncotarget. 2016; 7(31):49122-49129.

    12. Chang J, Pan F, Tang Q, Wu W*, Chen M, Lu C, Ding H, Hu L, Chen D, Xia Y, Wang X. eNOS gene T786C, G894T and 4a4b polymorphisms and male infertility susceptibility: a meta-analysis. Andrologia. 2016; doi: 10.1111/and.12646.

    13. Hu W, Chen M, Wu W*, Lu J, Zhao D, Pan F, Lu C, Xia Y, Hu L, Chen D, Sha J, Wang X. Gene-gene and gene-environment interactions on risk of male infertility: Focus on the metabolites. Environ Int. 2016; 91:188-195.

    14. Pan B, Li R, Chen Y, Tang Q, Wu W*, Chen L, Lu C, Pan F, Ding H, Xia Y, Hu L, Chen D, Sha J, Wang X. Genetic Association Between Androgen Receptor Gene CAG Repeat Length Polymorphism and Male Infertility: A Meta-Analysis. Medicine (Baltimore). 2016; 95(10):e2878.

    15. Yuan B, Gu H, Xu B, Tang Q, Wu W*, Ji X, Xia Y, Hu L, Chen D, Wang X. Effects of Gold Nanorods on Imprinted Genes Expression in TM-4 Sertoli Cells. Int J Environ Res Public Health. 2016; 13(3). pii: E271.

    16. Lu J, Gu H, Tang Q, Wu W*, Yuan B, Guo D, Wei Y, Sun H, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X. Common SNP in hsa-miR-196a-2 increases hsa-miR-196a-5p expression and predisposes to idiopathic male infertility in Chinese Han population. Sci Rep. 2016; 6:19825.

    17. Zhou R, Wang R, Qin Y, Ji J, Xu M, Wu W, Chen M, Wu D, Song L, Shen H, Sha J, Miao D, Hu Z, Xia Y, Lu C, Wang X. Mitochondria-related miR-151a-5p reduces cellular ATP production by targeting CYTB in asthenozoospermia. Sci Rep. 2015; 5:17743.

    18. Li J, Chen L, Tang Q, Wu W*, Gu H, Liu L, Wu J, Jiang H, Ding H, Xia Y, Chen D, Hu Y, Wang X. The role, mechanism and potentially novel biomarker of microRNA-17-92 cluster in macrosomia. Sci Rep. 2015; 5:17212.

    19. Ji J, Qin Y, Ren J, Lu C, Wang R, Dai X, Zhou R, Huang Z, Xu M, Chen M, Wu W, Song L, Shen H, Hu Z, Miao D, Xia Y, Wang X. Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN. Sci Rep. 2015; 5:16262.

    20. Ju R, Wu W (co-first author), Tang Q, Wu D, Xia Y, Wu J, Wang X. Association Analysis between the Polymorphisms of HSD11B1 and H6PD and Risk of Polycystic Ovary Syndrome in Chinese Population. PLoS One. 2015; 10(10):e0140326.

    21. Lu C, Xu M, Wang R, Qin Y, Ren J, Wu W, Song L, Wang S, Zhou Z, Shen H, Sha J, Hu Z, Xia Y, Miao D, Wang X. A genome-wide association study of mitochondrial DNA in Chinese men identifies two risk single nucleotide substitutions for idiopathic oligoasthenospermia. Mitochondrion. 2015; 24:87-92.

    22. Tang W, Tang J, He J, Zhou Z, Qin Y, Qin J, Li B, Xu X, Geng Q, Jiang W, Wu W, Wang X, Xia Y. SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease. J Cell Mol Med. 2015; 19(6):1197-207.

    23. Ju R, Wu W (co-first author), Fei J, Qin Y, Tang Q, Wu D, Xia Y, Wu J, Wang X. Association analysis between the polymorphisms of HSD17B5 and HSD17B6 and risk of polycystic ovary syndrome in Chinese population. Eur J Endocrinol. 2015; 172(3):227-33.

    24. Tang W, Li H, Tang J, Wu W, Qin J, Lei H, Cai P, Huo W, Li B, Rehan V, Xu X, Geng Q, Zhang H, Xia Y. Specific serum microRNA profile in the molecular diagnosis of Hirschsprung's disease. J Cell Mol Med. 2014; 18(8):1580-7.

    25. Zhao M, Tang Q, Wu W (corresponding author), Xia Y, Chen D, Wang X. miR-20a contributes to endometriosis by regulating NTN4 expression. Mol Biol Rep. 2014; 41(9):5793-7.

    26. Jiang H, Wu W (co-first author), Zhang M, Li J, Peng Y, Miao T, Zhu H, Xu G. Aberrant upregulation of miR-21 in placental tissues of macrosomia. J Perinatol. 2014; 34(9):658-63.

    27. Zhang S, Tang Q, Wu W*, Yuan B, Lu C, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X. Association between DAZL polymorphisms and susceptibility to male infertility: systematic review with meta-analysis and trial sequential analysis. Sci Rep. 2014; 4:4642.

    28. Qin Y, Ji J, Du G, Wu W, Dai J, Hu Z, Sha J, Hang B, Lu C, Xia Y, Wang X. Comprehensive pathway-based analysis identifies associations of BCL2, GNAO1 and CHD2 with non-obstructive azoospermia risk. Hum Reprod. 2014; 29(4):860-6.

    29. Qin Y, Du G, Chen M, Hu W, Lu C, Wu W, Hang B, Zhou Z, Wang X, Xia Y. Combined effects of urinary phytoestrogens metabolites and polymorphisms in metabolic enzyme gene on idiopathic male infertility. Arch Toxicol. 2014; 88(8):1527-36.

    30. Zhou Z, Qin J, Tang J, Li B, Geng Q, Jiang W, Wu W, Rehan V, Tang W, Xu X, Xia Y. Down-regulation of MeCP2 in Hirschsprung's disease. J Pediatr Surg. 2013; 48(10):2099-2105.

    31. Tang W, Qin J, Tang J, Zhang H, Zhou Z, Li B, Geng Q, Wu W, Xia Y, Xu X. Aberrant reduction of MiR-141 increased CD47/CUL3 in Hirschsprung's disease. Cell Physiol Biochem. 2013; 32(6):1655-67.

    32. Xu M, Qin Y, Qu J, Lu C, Wang Y, Wu W, Song L, Wang S, Chen F, Shen H, Sha J, Hu Z, Xia Y, Wang X. Evaluation of Five Candidate Genes from GWAS for Association with Oligozoospermia in a Han Chinese Population. PLoS One. 2013; 8(11):e80374.

    33. Lu C, Xu M, Wang R, Qin Y, Wang Y, Wu W, Song L, Wang S, Shen H, Sha J, Miao D, Hu Z, Xia Y, Wang X. Pathogenic variants screening in five non-obstructive azoospermia-associated genes. Mol Hum Reprod. 2013; 20(2):178-83.

    34. Tang Q, Li J, Zhang S, Yuan B, Sun H, Wu D, Lu C, Wu W (corresponding author), Xia Y, Ding H, Hu L, Chen D*, Sha J*, Wang X. GSTM1 and GSTT1 Null Polymorphisms and Childhood Acute Leukemia Risk: Evidence from 26 Case-Control Studies. PLoS One. 2013; 8(10):e78810.

    35. Xu S, Xu P, Wu W, Ou Y, Xu J, Zhang G, Li J, Xu G. The biphasic expression pattern of miR-200a and E-cadherin in epithelial ovarian cancer and its correlation with clinicopathological features. Curr Pharm Des. 2014; 20(11):1888-95.

    36. Wu W*, Lu J, Tang Q, Zhang S, Yuan B, Li J, Di Wu, Sun H, Lu C, Xia Y, Chen D, Sha J, Wang X. GSTM1 and GSTT1 null polymorphisms and male infertility risk: an updated meta-analysis encompassing 6934 subjects. Sci Rep. 2013; 3:2258. 

    37. Xu C, Song RJ, Yang J, Jiang B, Wang XL, Wu W, Zhang W. Klotho gene polymorphism of rs3752472 is associated with the risk of urinary calculi in the population of Han nationality in Eastern China. Gene. 2013; 526(2):494-7.

    38. Lu C, Wang Y, Zhang F, Lu F, Xu M, Qin Y, Wu W, Li S, Song L, Yang S, Wu D, Jin L, Shen H, Sha J, Xia Y, Hu Z, Wang X. DAZ duplications confer the predisposition of Y chromosome haplogroup K* to non-obstructive azoospermia in Han Chinese populations. Hum Reprod. 2013; 28(9):2440-9.

    39. Wu W*, Lu J, Chen D, Yuan B, Qin Y, Han X, Niu X, Xu B, Lu C, Xia Y, Sha J, Wang X. Association of prostate cancer susceptibility variant (MSMB) rs10993994 with risk of spermatogenic failure. Gene. 2013; 524:197-202.

    40. Tang W, Li B, Tang J, Liu K, Qin J, Wu W, Geng Q, Zhang J, Chen H, Xu X, Xia Y. Methylation analysis of EDNRB in human colon tissues of Hirschsprung's disease. Pediatr Surg Int. 2013; 29:683-8.

    41. Lv Q, Lu J, Wu W, Sun H, Zhang J. Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with stroke risk based on a meta-analysis. Genet Mol Res. 2013; 12(4):6882-94.

    42. Wu W, Qin Y, Li Z, Dong J, Dai J, Lu C, Guo X, Zhao Y, Zhu Y, Zhang W, Sha J, Shen H, Xia Y, Hu Z, Wang X. Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p. Hum Reprod. 2013; 28:1827-36.

    43. Qin Y, Chen M, Wu W (co-first author), Xu B, Tang R, Chen X, Du G, Lu C, Meeker JD, Zhou Z, Xia Y, Wang X. Interactions between Urinary 4-tert-Octylphenol Levels and Metabolism Enzyme Gene Variants on Idiopathic Male Infertility. PLoS One. 2013; 8:e59398.

    44. Tang Q, Wu W (co-first author), Xu X, Huang L, Gao Q, Chen H, Sun H, Xia Y, Sha J, Wang X, Chen D, Xu Q. miR-141 Contributes to Fetal Growth Restriction by Regulating PLAG1 Expression. PLoS One. 2013; 8:e58737.

    45. Lu C, Xu M, Wang Y, Qin Y, Du G, Wu W, Han X, Ji C, Yang Y, Gu A, Xia Y, Song L, Wang S, Wang X. Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese population. PLoS One. 2013; 8:e53443.

    46. Xu S, Wu W (co-first author), Sun H, Lu J, Yuan B, Xia Y, Moor B, Marchal K, Wang X, Xu P, Cheng W. Association of the vascular endothelial growth factor gene polymorphisms (-460C/T, +405G/C, and +936T/C) with endometriosis: a meta-analysis. Ann Hum Genet. 2012; 76:464-471.

    47. Chen M, Xu B, Ji W, Qiao S, Hu N, Hu Y, Wu W, Qiu L, Zhang R, Wang Y, Wang S, Zhou Z, Xia Y, Wang X. Bisphenol A Alters n-6 Fatty Acid Composition and Decreases Antioxidant Enzyme Levels in Rat Testes: A LC-QTOF-Based Metabolomics Study. PLoS One. 2012; 7:e44754.

    48. Tang W, Li B, Xu X, Zhou Z, Wu W, Tang J, Qin J, Geng Q, Jiang W, Zhang J, Sha J, Xia Y, Wang X. Aberrant high expression of NRG1 gene in Hirschsprung disease. J Pediatr Surg. 2012; 47:1694-1698.

    49. Han X, Tang R, Chen X, Xu B, Qin Y, Wu W, Hu Y, Xu B, Song L, Xia Y, Wang X. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) decreases progesterone synthesis through cAMP-PKA pathway and P450scc downregulation in mouse Leydig tumor cells. Toxicology. 2012; 302:44-50.

    50. Zhao D, Wu W (co-first author), Xu B, Niu X, Cui H, Zhang Y, Wang Z, Wang X. Variants in the SRD5A2 gene are associated with quality of semen. Mol Med Report. 2012; 6:639-644. More....

    URL of Official website: http://gwxy.njmu.edu.cn/yxjs/ShowArticle.asp?ArticleID=1734

    Grant details: 

    1. National key research and development project: The establishment and basic research for application of China Assisted reproductive birth cohort population and the offspring cohort of the Chinese population. 2016/7-2021/6, ￥280900.

    2. National Natural Science Foundation of China (81673217): The study of role and molecular mechanisms of the DSTF1/miR-125-3p/Fstl3 pathway in the transgenerational spermatogenic failure caused by prenatal DBP exposure. 2017/1-2020/12, ￥600000.

    3. China Postdoctoral Science Foundation (2015T80571): The role and molecular mechanisms of human miR-483-3p in the BP-3 induced fetal macrosomia. 2015/7-2017/6, ￥150000.

    4. National Natural Science Foundation of China (81302457): Effect and mechanism of miR-17-92 gene cluster in spermatogenic failure induced by genistein exposure. 2014/1-2016/12, ￥240000

    5. Jiangsu Natural Science Foundation (BK20130894): The role and molecular mechanisms of miR-200s family in spermatogenic failure induced by genistein exposure. 2013/7-2016/6, ￥200000.

    6. China Postdoctoral Science Foundation (2013M531388): The role and molecular mechanism of imprinted lncRNA-H19 in fetal growth restriction. 2013/3-2015/2, ￥50000. Science and Technology Development Fund Key Project of Nanjing Medical University (2012NJMU002): Environment and epigenetics risk factors and their interactions in spermatogenic failure. 2012/12-2014/12, ￥30000.

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    Editorial Board

    Emil Bulatov
    Group Leader
    Institute of Fundamental Medicine and Biology
    Kazan Federal University
    Russian Federation
    chembio.kazan@gmail.com
    AMGM

    2015 – PhD, University of Cambridge, UK

    2010 – MPhil, Newcastle University, UK

    Research Interest: Molecular and cell biology, immunology, oncology

    Grants: Russian Foundation of Basic Research
    (#16-34-60213; #16-34-50250; #17-34-50167; # 19-54-10005)

    URL: https://kpfu.ru/emil.bulatov?p_lang=2

    List of Publications:

    Articles and conference abstracts
    (2018) Article.
    1. Emil Bulatov, Regina Sayarova, Rimma Mingaleeva, Regina Miftakhova, Marina Gomzikova, Yuri Ignatyev, Alexey Petukhov, Pavel Davidovich, Albert Rizvanov and Nickolai Barlev / Isatin-Schiff base-copper (II) complex induces cell death in p53-positive tumors // Cell Death Discovery, 4: 103 (2018)
    DOI: 10.1038/s41420-018-0120-z
    https://www.nature.com/articles/s41420-018-0120-z

    (2018) Quartile Q1. Article.
    2. Aleksei Titov, Alexey Petukhov, Alena Staliarova, Dmitriy Motorin, Emil Bulatov, Oleg Shuvalov, Surinder M. Soond, Mauro Piacentini, Gerry Melino, Andrey Zaritskey & Nickolai A. Barlev. The biological basis and clinical symptoms of CAR-T therapy-associated toxicites // Cell Death & Disease, 9, Article: 897 (2018)
    Impact Factor = 6.187
    DOI: 10.1038/s41419-018-0918-x
    https://www.nature.com/articles/s41419-018-0918-x

    (2018) Quartile Q2. Article.
    3. Emil Bulatov, Aygul Valiullina, Regina Sayarova, Albert Rizvanov. Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases. Immunology Letters, 2018, 202, 44-51.
    Impact Factor = 2.664 
    DOI: 10.1016/j.imlet.2018.08.001
    https://www.sciencedirect.com/science/article/pii/S0165247817306077

    (2018) Quartile Q1. Article.
    4. Bulatov E, Zagidullin A, Valiullina A, Sayarova R, Rizvanov A. Small molecule modulators of RING-type E3 ligases: MDM and cullin families as targets // Frontiers in Pharmacology, 2018, 9, Article 450.
    Impact Factor = 4.439
    DOI: 10.3389/fphar.2018.00450
    https://www.frontiersin.org/articles/10.3389/fphar.2018.00450/full
    WOS:000431660700001

    (2018) Quartile Q1. Article.
    5. Vafina, G., Zainutdinova, E., Bulatov, E., Filimonova, M.N. Endonuclease from gram-negative bacteria Serratia marcescens is as effective as pulmozyme in the hydrolysis of DNA in sputum. // Frontiers in Pharmacology, 2018, 9,  Article 114.
    Impact Factor  = 4.439
    DOI: 10.3389/fphar.2018.00114
    https://www.frontiersin.org/articles/10.3389/fphar.2018.00114/full
    WOS:000425298100001

    (2018)
    Monography (27 pages).
    6. Emil Bulatov. E3 ubiquitin ligases as targets for small molecule drug discovery: focus on Cullin RING family.
    Глава в книге "Ubiquitin Proteasome System: A Review and Directions for Research". Hardcover edited collection (by selected invitation only). Nova Science Publishers, Inc., USA.
    https://www.novapublishers.com/catalog/product_info.php?products_id=64423

    (2018) Quartile Q2. Conference thesis.
    7. Glagoleva, I., Kudriaeva, A., Belogurov, A., Rizvanov, A. and Bulatov, E. / Effect of Nutlin-3a, RG-7112, Carfilzomib and MG-132 on accumulation of p53 in eukaryotic HEK293 cell line // European Journal of Clinical Investigation, 2018, 48, 100
    Impact Factor = 2.707
    WOS:000434100200222
    DOI: 10.1111/eci.12926

    (2017) Quartile Q1. Conference thesis.
    8. A. Valiullina, M. Gomzikova, T. Khaibullin, A. Rizvanov & E. Bulatov. Regulation of p53-dependent genes expression in multiple sclerosis: the effect of MDM2 inhibitor Nutlin-3a. // European Journal of Clinical Investigation, 2017, 47 (Suppl. 1), 141–142
    Impact Factor = 2.714
    DOI: 10.1111/eci.12749
    https://kpfu.ru//staff_files/F1836875316/ESCI_141_142.pdf
    WOS:000412099900326

    (2017) Quartile Q1. Conference thesis.
    9. Aygul Kh. Valiullina, Marina Gomzikova, Ekaterina E. Garanina, Timur Khaibullin, Albert Rizvanov, and Emil Bulatov. Small Molecule p53-MDM2 Inhibitors As Potential Regulators of p53-Dependent Genes Expression in Multiple Sclerosis. // Blood, 2017, 130:4820
    Impact Factor = 13.164
    http://www.bloodjournal.org/content/130/Suppl_1/4820

    (2017) Quartile Q2. Conference thesis.
    10. A. Valiullina, M. Gomzikova, T. Khaibullin, E. Garanina, E. Zmievskaya, A. Rizvanov, E. Bulatov. Effect of p53 activation on target gene expression and cytokine release in peripheral blood mononuclear cells. // Mol. Biol. Cell, 2017, vol. 28, no. 26, 545-546
    Impact Factor = 3.685
    DOI: 10.1091/mbc.E17-10-0618
    https://kpfu.ru//staff_files/F_1215039000/2017ASCB_545_546.pdf

    (2016) Quartile Q2. Conference thesis.

    11. Валиуллина, А.Х., Саярова, Р.М., Соловьева, В.В., Ризванов, А.А., Булатов Э.Р. Изучение роли белков р53 и MDM2 в качестве потенциальных регуляторов аутоиммунных процессов при рассеянном склерозе. // Acta Naturae, 2016, спецвыпуск, том 2, с. 66
    Impact Factor = 1.770
    http://kpfu.ru//staff_files/F1913808647/2016_ActaNaturae_66.pdf

    (2016) Quartile Q3. Article.
    12. Vafina G, Bulatov E, Zaynutdinova E, Filimonova M. A One-Step Protocol for Chromatographic Purification of Non-recombinant Exogenous Bacterial Enzyme: Nuclease of Serratia marcescens // BioNanoScience. - 2016. - Vol.6, Is.4. - P.335-337.
    CiteScore (Scopus) = 1.48
    DOI: 10.1007/s12668-016-0226-9
    https://link.springer.com/article/10.1007/s12668-016-0226-9
    WOS:000390587700015

    (2016) Quartile Q3. Article.
    13. Bulatov, E., Khaiboullina, S, dos Reis, H.J., Palotás, A., Venkataraman, K., Vijayalakshmi, M., Rizvanov, A. Ubiquitin-Proteasome System: Promising Therapeutic Targets in Autoimmune and Neurodegenerative Diseases // BioNanoScience. - 2016. - Vol.6, Is.4. - P.341-344.
    CiteScore (Scopus) = 1.48
    DOI: 10.1007/s12668-016-0233-x
    https://link.springer.com/article/10.1007/s12668-016-0233-x
    WOS:000390587700017

    (2016) Quartile Q2. Conference thesis.
    14. P. Davidovich, R. Sayarova, A. Valiullina, V. Solovyeva, M. Gomzikova, A. Smirnov, A. Rizvanov,
    E. Bulatov.     Novel isatin-Schiff base copper (II) complexes as potential p53-activating pro-apoptotic agents. // Mol. Biol. Cell, 2016, 27:25, 3947, 708.
    Impact Factor = 4.037
    DOI: 10.1091/mbc.E16-10-0736
    http://www.molbiolcell.org/content/suppl/2016/12/08/27.25.3947.DC1/2016ASCBMeeting-PosterAbstracts.pdf
    WOS:000396047100121

    (2016) Quartile Q1. Conference thesis.
    15. Bulatov E., Valiullina A., Sayarova R., Rizvanov A. Inhibitors of MDM2 ubiquitin ligase as prospective modulators of autoimmunity // FEBS JOURNAL. - 2016. - Vol.283, Is.. - P.360-360.
    Impact Factor = 4.237
    DOI: 10.1111/febs.13808
    http://onlinelibrary.wiley.com/doi/10.1111/febs.13808/epdf
    WOS:000383616901715

    (2015) Quartile Q1. Article.
    16. Gadd, M. S., Bulatov, E. and Ciulli, A. Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases. // PLoS ONE 2015, 10, e0131218.
    Impact Factor = 3.234
    DOI: 10.1371/journal.pone.0131218
    WOS:000358150400086

    (2015) Quartile Q1. Article.
    17. Bulatov, E. and Ciulli, A. Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation. // Biochem. J. 2015, 467, 365–386.
    Impact Factor = 3.85
    DOI: 10.1042/BJ20141450
    WOS:000353217200002

    (2015) Quartile Q1. Article.
    18. Bulatov, E., Martin, E. M., Chatterjee, S., Knebel, A., Shimamura, S., Konijnenberg, A., Johnson, C., Zinn, N., Grandi, P., Sobott, F., Ciulli, A. Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2). // J. Biol. Chem. 2015, 290, 4178–4191.
    Impact Factor 2014 = 4.253
    DOI: 10.1074/jbc.M114.616664
    Article recommended by F1000Prime in Technical Advance category
    WOS:000349458400029

    Theses:
    1. Emil Bulatov. PhD Thesis. Interactions, assembly and fragment screening of the multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 ubiquitin ligase. University of Cambridge, UK, 2015.

    2. Emil Bulatov. MPhil Thesis. Identification and Validation of a Series of P53-MDM2 and P53-MDMX Protein-protein Interaction Inhibitors. Newcastle University, UK, 2010.

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    Rasoul Alikhani Koupaei
    Professor
    Department of Genetic Disease
    Genetic Disease Laboratory
    USA
    rasoul.alikhani@gmail.com
    AMGM

    Research Interest: Newborn screening; Prenatal screening; Method development; Inborn Error of metabolism; Biochemical Genetics.

    More Info.
    Wenquan Niu
    Associate Professor
    Shanghai Jiao Tong University School of Medicine
    China
    niuwenquan_shcn@163.com
    AMGM

    Research Interest: Human genomics,Genetic epidemiology,Biostatistics,Evidence-based medicine.

    More Info.
    Yan-Wei Yin
    Assistant Professor
    Department of Emergency
    Chinese PLA Air Force General Hospital
    China
    weiyyk@163.com
    AMGM

    Research Interest: Molecular genetics, Atherosclerosis, Inflammation and Meta-analysis.

    More Info.
    Neslihan Saygili
    Researcher
    Department of Molecular Medicine
    Istanbul University
    Turkey
    isikeslihan@gmail.com
    AMGM

    Research Interest: Molecular cancer, pharmacogenetics, cell culture analysis.

    More Info.
    Anton Kiselev
    senior scientist
    Department of Ott Research Institute of Obstetrics
    D. O. Ott Research Institute of Obstetrics and Gynecology RAMS
    Russia
    ankiselev@yahoo.co.uk
    AMGM

    Research Interest: Gene therapy, non-viral gene delivery, inherited neuromuscular diseases,

    peptide-based carriers, Duchenne muscular dystrophy, polyplex, transfection, siRNA delivery,

    spinal muscular atrophy, genetic testing.

    More Info.
    Marta Adonis
    Assistant Professor
    niversity of Chile
    Chile
    madonis@med.uchile.cl
    AMGM

    Research Interest: Science and Medicine.

    More Info.
    Jim Jinn-Chyuan Sheu
    Professor
    Human Genetic Center China Medical University Hospital
    China
    jimsheu@mail.nsysu.edu.tw
    AMGM

    Research Interest: Cancer genetics and genomics, epigenetics, chromatin remodeling, signal transduction profiling, new drug discovery & development, complementary & alternative medicine, antibody/vaccine engineering.

    More Info.
    Aaron Matthew Elliott
    Department of Ambry Genetics
    USA
    aelliott@ambrygen.com
    AMGM

    Research Interest: Next-Generation Sequencing, target enrichment, diagnostics, hereditary disease, targeted therapy.


    More Info.
    Ramon Cacabelos
    Professor
    Camilo Jose Cela University
    Spain
    rcacabelos@euroespes.com
    AMGM

    Research Interest: Genomics of Brain Disorders; Epigenomics; Pharmacogenomics;   Pharmacoepigenomics; Proteomics; Metabolomics; Nutrigenomics.


    More Info.
    Chen Chen
    Assistant Professor
    Division of Cardiology
    Huazhong University of Science and Technology
    PR China
    chenchen@tjh.tjmu.edu.cn
    AMGM

    Research Interest: The effects and mechanisms of miRNA involved in cardiocascular system and cancers; The protective effects of Arachidonic acid Cytochrome P450 epoxygenase on cardiovascular system and relevant mechanisms; Cytochrome P450 and human cancers, focus on the roles of P450 epoxygenases on proliferation, metastasis and apoptosis of human cancers, also inhibition of human cancer growth by P450 epoxygenase inhibitors.


    More Info.
    Jianxiu Yu
    Professor
    Department of Biochemistry and Molecular Cell Biology
    Shanghai Jiao Tong University School of Medicine
    China
    jianxiu.yu@gmail.com
    AMGM

    Research Interest: Non-coding RNA(miRNA/lncRNA), protein modifications, tumor suppressor, tumorigensis, metastasis, prostate cancer.

    More Info.
    Andrey A Zamyatnin
    Head
    I.M. Sechenov First Moscow State Medical University
    Russia
    zamyat@belozersky.msu.ru
    AMGM

    Research Interest: Programmed cell death, protein processing, intracellular communications, virus‐cell interactions, regulation of gene expression, RNAi, oxidative stress, aging, neurodegeneration, ophthalmology, cancer, regenerative medicine, personalized medicine, molecular markers, novel drug candidates.

    More Info.
    Atif Ahmed
    Childrens Mercy Hospital Pathology & Laboratory Medicine
    USA
    atifaahmed@msn.com
    AMGM

    Research Interest: organ pathology and effect of novel treatments in mouse model of lupus nephritis.


    More Info.
    Yi Zhang
    Professor
    Department of Oncology
    Zhengzhou University
    China
    yizhang@zzu.edu.cn
    AMGM

    Research Interest: Cancer treatment,) Tumor infiltrating lymphocytes ,immune cells, in tumor microenvironment,Caner stem cell,Myeloid-derived suppressor cells.

    More Info.
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    Table of Contents
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    mendeley

    A summary of the molecular testing recommended in acute myeloid leukemia

    DOI Logo 10.17352/amgm.000007

    Published On: April 18, 2020 | Pages: 012 - 017

    Author(s): Ruth Stuckey, Cristina Bilbao-Sieyro and María Teresa Gómez-Casares*
    Abstract View Full Article View
    mendeley

    Expression of blaCTX-M2 and invA genes of Salmonella Heidelberg isolated from poultry by Qpcr

    DOI Logo 10.17352/amgm.000006

    Published On: April 16, 2020 | Pages: 006 - 011

    Author(s): Gabriella Bassi das Neves, Denise Nunes Araújo, Eduarda Pick, Dinael Simão Bitner, Maiara Cristiane Brisola, Regiane Boaretto Crecencio, and Lenita Moura Stefani*
    Abstract View Full Article View
    mendeley

    Association of KIR haplotypes with propensity for developing chronic hepatitis B induced liver diseases (cirrhosis and hepatocellular carcinoma) and HIV-1 infection in a West African Cohort

    DOI Logo 10.17352/amgm.000005

    Published On: March 20, 2020 | Pages: 001 - 005

    Author(s): Florencia Wendkuuni Djigma, Pegdwendé Abel Sorgho, Marius Ayaovi Setor, Bolni Marius Nagalo, Bayala Bagora, Lassina Traore, Christelle WM Nadembega, Djeneba Ouermi, Albert Théophane Yonli and Simpore Jacques*
    Abstract View Full Article View
    mendeley

    Genetic testing

    DOI Logo 10.17352/amgm.000004

    Published On: December 27, 2019 | Pages: 001 - 001

    Author(s): Roopa Bijja*
    Abstract View Full Article View
    mendeley

    New emerging Genetic Disease: A Case Study in Southeast Asia and a new interesting reason

    DOI Logo 10.17352/amgm.000003

    Published On: May 22, 2017 | Pages: 013 - 013

    Author(s): Beuy Joob* and Viroj Wiwanitkit
    Abstract View Full Article View
    mendeley

    Influence of Concentration on Surface Tension & Viscosity of Tamarind (Tamarindus Indica) Seed Gum

    DOI Logo 10.17352/amgm.000002

    Published On: April 04, 2017 | Pages: 008 - 012

    Author(s): Sunita Thakur*, Pramod Kumar Sharma and Rishabha Malviya
    Abstract View Full Article View
    mendeley

    Micronutrient-Induced Activation of Nrf2 and -Elevation of Intracellular Antioxidants for Reducing Oxidative Stress and Chronic Infl ammation in Diabetes

    DOI Logo 10.17352/amgm.000001

    Published On: March 18, 2017 | Pages: 001 - 007

    Author(s): Kedar N Prasad*
    Abstract View Full Article View

     

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    Editor-in-Chief

    Wei Min HUANG
    Nanyang Technological University, Singapore
    Archive of Biomedical Science and Engineering
    Domenico Antonio Restivo
    Nuovo Garibaldi Hospital, Italy
    Journal of Neurology, Neurological Science and Disorders
    Thomas Muller
    Saint Joseph Hospital , Germany
    Journal of Neurology, Neurological Science and Disorders
    Stavros Dimopoulos
    University of Athens, Greece
    Journal of Novel Physiotherapy and Physical Rehabilitation
    Nicholas Kipshidze
    Cardiovascular Research Foundation, New York, USA
    Archives of Clinical Hypertension
    Giuseppe Murdaca
    University of Genoa, Italy
    Global Journal of Allergy
    Miklas Scholz
    Lund University, Sweden
    Annals of Environmental Science and Toxicology
    Zhongchang Wang
    International Iberian Nanotechnology Laboratory (INL), Portugal
    International Journal of Nanomaterials, Nanotechnology and Nanomedicine
    Peter J Catalano
    Tufts University, USA
    Archives of Otolaryngology and Rhinology
    Giorgio Bianciardi
    University of Siena, Italy
    International Journal of Oral and Craniofacial Science

    Global Views

    NIH Funded Articles

    Ethnic Differences in Abstinence Self-Efficacy among Recovering Individuals Intranuclear inclusions in conventional clear cell Renal Cell Carcinoma (RCC): A case report and review of the literature Significance of Cancer Stem Cells in Anti-Cancer Therapies Buprenorphine Maintenance for Opioid Dependence in Public Sector Healthcare: Benefits and Barriers Diabetic Retinopathy: Focus on Minority Populations How Anterior Cruciate Ligament Injury was averted during Knee Collapse in a NBA Point Guard Validity of Ratings of Perceived Exertion in Patients with Type 2 Diabetes Endothelial Progenitor Cells in Breast Cancer Hepatitis B Vaccination Rate in Patients with Diabetes: Assessment of Racial and Socioeconomic Disparity Neural Response During a Mechanically Assisted Spinal Manipulation in an Animal Model: A Pilot Study

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    Research Articles

    Diagnostic utility of point of care high sensitive troponin-i assay for early diagnosis of acute myocardial infarction in patients presenting with acute onset chest pain in emergency departments. The early heart study
    March 12, 2020    Different Levels of Exhaled Nasal Nitric Oxide in Patients Diagnosed with Primary Dyskinesia
    July 07, 2015    ATG Based Conditioning Regimen in Stem Cells Transplantation of Fanconi Anemia: A Single Center Experience of 63 Patients
    March 08, 2017

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