Research Interest:My
Research for the Past Eight Years has been focusing on Metastatic Mechanism of
Hepatocellular Carcinoma (HCC) and Pancreatic Adenocarcinoma (PDA). My Medical
Training help me understand The Pathophysiology and Current Therapeutic Needs
of these Lethal Disease. I have accumulated Extensive Experience in studying the
Biology and underlying mechanism of HCC as well as PDA Using Various in Vitro
or in Vivo Model Systems, Especially Clinical Analysis of Multicenter, large samples.
My Work in this Field has helped us understand the Abnormal Increase in
Aggressiveness of Residual HCC Cells after Tumor Blood Blocking with Related to
Activation of Wnt/Β-Catenin Signaling and Subsequent Elicitation of
Epithelial-Mesenchyme Transition. It Meanwhile Identified the
Metastasis-Promoted Role of Caveolin-1 in PDA and Clarified its Regulation. These
Works have Generated Several High Impact Publications in Clin Cancer Res, Oncogene,
Cancer Letts, and Int J Cancer Respectively.