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    Editor-in-Chief

    Wei Min HUANG

    Wei Min HUANG
    Nanyang Technological University, Singapore
    Email: shape_memory_material@hotmail.com, mwmhuang@ntu.edu.sg
    Tel: 0065 84664500
    Fax: 0065 67924062
    Skype: shape_memory_material@hotmail.com

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    Executive Editors

    Carlo Massaroni
    School of Engineering
    Università Campus Bio-Medico di Roma
    Italy
    c.massaroni@unicampus.it
    ABSE

    Carlo Massaroni was born in Anzio (Rome) in 1988.

    He received the B.S. Degree in Biomedical Engineering from Università Campus Bio-Medico di Roma in December 2010. The Bachelor thesis title was "Perception Analysis of the form by the use of a numerical chessboard" and it was carried out in collaboration with the Bioinformatics Lab of the same University.

    He received the M.S. Degree  with highest honors in Biomedical Engineering from Università Campus Bio-Medico di Roma in December 2012. His graduation Thesis was entitled "Preliminary validation of a respiratory apparatus simulator for the assessment of metrological characteristics of a optoelectronic plethysmograph".

    With his thesis he won two relevant National Price. On September he has been awarded the 2013 SIAMOC Dissertation Prize by the Italian Society of Clinical Movement Analysis (SIAMOC) in recognition of the outstanding quality of his undergraduate research. On October he has been awarded the 2013 GNB Dissertation Price by the Italian National Bioengineering Group (GNB) for outstanding contribute in the field of Rehabilitation and Prosthetics.

    From April 2013 to January 2014 he worked as Biomechanical Researcher in the Unit of Rehabilitation at Scientific Institute for Research IRCCS Eugenio Medea of Conegliano (TV), as Scholarship Winner and Assignee for 2013.

    He was PhD Student in Biomedical Engineering at Università Campus Bio-Medico di Roma from January 2014 to December 2016: he started working in the Laboratory of Measurements and Biomedical Instrumentation in January 2014, under the supervision of Prof. Sergio Silvestri.

    In 2014 he has achieved the Professional Qualification as Industrial Engineer (Section A). He was Jury Aggregate Member as Topic expert in Biomedical Instrumentation during the State Examinations enabling the exercise of the profession of Engineer on behalf of Ordine degli Ingegneri of Rome. Section A - Industrial Section.

    From February 2015 is Student Mentor for the International Biomechanics Society (ISB) in Instrumentation for Human Motion, Optoelectronic Systems and Optoelectronic Plethysmography.  

    On July 2015 he has been awarded the International Grant Travel Program Award by the International Society of Biomechanics (ISB) with the project "MoCBA - MOtion Capture for Breathing Assessment". MoCBA is an interdisciplinary project taking advantage of the research cooperation between the School of Sport & Exercise Sciences (SSES) at the University of Kent (Dr. Dickinson and Dr. Winter) and the School of Engineering, Research Unit of Measurement and Biomedical Instrumentation (UCBM) at the Campus Bio-Medico di Roma University. He is currently (until 22/04/2016) a Visiting PhD Student  at University of Kent (Medway Campus, Kent, UK), where he is working in the Respiratory Clinic Unit.

    On September 2017 he has been awarded the 2017 GNB Thesis Award by the Italian National Bioengineering Group (GNB) for outstanding contribute in the field of Biorobotics and Biomechanics.

    URL: http://mtmbilaben.weebly.com/carlo-massaroni.html

    Grant Details:

    2017 IEEE Sensor Council Travel Award (€ 1000) to attend the 2nd IEEE Sensors Summer
    School on Optical Fibre Sensors at the University of Limerick, Ireland. 26th – 30th
    June 2017 - Limerick, Ireland.
    2016 European Society of Biomechanics (ESB) Travel Award (€ 400) to attend the 22nd
    Congress of the European Society of Biomechanics (Respiratory Biomechanics
    Session) - Lyon, France.
    2015 International Society of Biomechanics (ISB) International Travel Grant (ITG2015) ($
    2500) to fund the Research Project “MoCBA: Motion Capture for Breathing
    Assessment” and to fund the foreign period of 6 months at University of Kent (UK).

    Number of Publications: 43 </xml> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0in; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:EN-IN;} </style> List of Publications: 43

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    Editorial Board

    Jian Ye
    Associate Professor
    School of Biomedical Engineering
    Shanghai Jiao Tong University
    China
    yejian78@sjtu.edu.cn
    ABSE

    Research Interest: Design, fabrication, and optical properties of nanomaterials,- Biomedical applications (biosensing, bioimaging, therapy) of nanomaterials ,- Surface-enhanced Raman scattering and related biomedical applications

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    Xiao MA
    College of Urban and Environmental Sciences
    Hubei Normal University
    China
    maxiao81@126.com
    ABSE

    Research Interest:  Non-point source, soil heavy metal, absorbing Material, and restoration

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    Mohammed Rachidi
    Doctor
    Department of Sciences
    University Paris Diderot, Paris
    France
    rachidi.med1@yahoo.com
    ABSE

    Dr. Mohammed Rachidi received his PhD/ Doctorate Degree in Human and Molecular Genetics (with High Honors) at the prestigious ''Pasteur Institute'' (Paris, France), in the Department of Molecular and Cellular Genetics headed by the Professor François JACOB (Nobel Prize in Physiology/Medicine), where he studied the Cellular & Molecular Mechanisms underlying Brain Morphogenesis, Visual System development, CaMKinases & Biological Clock Function in Drosophila. Dr. Rachidi extended these Molecular Genetics works to Functional Genomics at Pasteur Institute and at Center National of Research Scientific CNRS and played key fundamental roles in different collaborative research projects with prestigious laboratories in Europe, Japan & United States. Remarkably, Dr. Rachidi collaborated with the Professor Michael ROSBASH (Nobel Prize in Physiology/Medicine 2017) in the Molecular Mechanisms of 2 genes involved in Circadian Clock.  Dr. Rachidi published with Professor ROSBASH this important work in the EMBO Journal Entitled : ''A New Gene encoding a putative Transcritpion Factor Regulated by the Drosophila Circadian Clock''. Postdoctoral training & Assistant Professor with Professor Nicole LeDOUARIN at the prestigious ''College De France'' & Institute of Cellular & Molecular Embryology (Paris), Dr. Rachidi studied some Chicken & Xenopus molecules acting in Bone Morphogenetic Protein BMP signaling pathways and identified their Mouse & Human homologs involved in differentiation of specific domains of neuronal progenitors, in cerebellum development and Joubert syndrome (a form of cerebellar ataxia). These experiences of Dr. Rachidi in the Molecular Genetics and in several Animal Models were extended to Human Molecular Genetics of Down syndrome (DS) & to Molecular and Cellular Mechanisms underlying Brain morphogenesis of Trisomic & Transgenic Mouse Models of DS and also of numerous stages of Embryonic & Fetal DS patients to elucidate the Neurogenetic Basis of Functional alterations Associated with Mental Retardation. Director of Research in Human Molecular Genetics, Faculty of Medicine University Paris 5 (France), with High Honours for Notable Scientific Research Contributions, Breakthroughs & Discoveries in Drosophila & Mouse & Human Molecular Genetics & Neurosciences, Dr. Rachidi has vast experiences with different Research Interests in Modern Molecular Genetics, Neuroscience & Biomedical Research. Dr. Rachidi realized numerous ''Discoveries and Innovations'' to name a few:  (1) - Discovery of Quantitative Assessment of Gene [removed]QAGE) as a New Method in situ detecting Differential Overexpression of Candidate Genes for Mental Retardation in Down syndrome Brain Regions & for Other Diseases caused by Regionalized Quantitative Transcriptional Alterations for greater interpretation of functional processes driving gene expression. (2) - Discovery of New Cerebellar & Cerebral Phenotypes in Transgenic mouse in vivo Library of Human Down syndrome Critical Region. (3) - Discovery of a Novel Light Microscopy Technology as Powerful Tool in Developmental Biology & Biomedical & Neuroscience Research. (4) - Discovery of New Genes involved in Brain Morphogenesis & in Visual System development; in Biological Clock; in Learning & Memory and in Mental Retardation in Down syndrome & Joubert syndrome. (5) - Discovery of the First Proposed Model of Molecular and Cellular Mechanism Elucidating Neurogenetic and Neurocognitive Basis of Functional Impairments Associated with Mental Retardation in Down syndrome: in this Model Gene Dosage Effects on transcriptional variations and the nature of gene products and their functional relationships are explained with the different aspects of neuronal differentiation. Dr. Rachidi published numerous articles in highly Prestigious International Journals with High Impact Factor like EMBO, Genomics, DNA Research, Gene, Mechanisms of Development, Cytogenetics & Genome Research, Neuroscience Research, International Journal of Developmental Neuroscience, Cell Tissue Research, American Journal of Intellectual Developmental Disability, European Journal of Paediatric Neurology...and in numerous journals of Elsevier & Springer. He has also authored numerous Chapters & Books. Dr. Rachidi has been honoured worldwide as Invited Distinguished Speaker, Chairman or Invited Honourable Organizing Committee Member in numerous International Conferences, Seminars & Workshops in Europe, USA & Asia. Dr Rachidi received numerous Awards & Honors and He is an Editor, Associate Editor, Executive Editor & Editor in Chief in numerous International peer-reviewed Journals.

    Research Interest:

    Dr. Mohammed Rachidi has vast experiences with different Research Interests in Modern Molecular Genetics, Neurosciences & Biomedical Research, to name a few : Cellular & Molecular Mechanisms underlying Brain Morphogenesis, Visual System, Biological Clock, Synaptic Protein Targeting, Synaptic Plasticity, CaMKII & CAMGUK/MAGUK, Learning and Memory. Functional Genomics & Mechanisms controlling Transposition at Cell Cycle. Transcription, Protein Translation & Virus-Like Particle Formation. Bone Morphogenetic Protein BMP signaling pathways, Mouse and Human Homeobox Genes, Cell Fate Determination and Differentiation, Neuronal Progenitors in Cerebellum development and Joubert syndrome. Trisomy 21, Intellectual Disability, Candidate Genes, Expression studies, Genotype-Phenotype Associations, Trisomic and Transgenic Mouse Models of Down syndrome, Neurogenetic and Neurocognitive Basis of Functional Impairments Associated with Intellectual Disability.  Drosophila & Mouse & Human.

    List of Publications:

    - Rachidi, M. (2019). Pharmacotherapeutic Challenges for Rescuing Mental Retardation and Improving Brain Function in Down Syndrome.  Biophamaceutics and Therapeutic Challenges, 2019, (In Press).

    - Rachidi, M. (2018). The Genetic Dosage Imbalance Linked to Clinical Brain Alterations and Mental Disability in Down syndrome could be Targeted for Therapeutics Development.
    Medical Journal of Clinical Trials and Case studies. 2018, 2 (5): 000150.

    - Rachidi, M. (2018). The Molecular Pathogenesis of Down Syndrome-Associated Diseases and the Promising Potential Therapeutic Targets.
    Clinical and Medical Investigations, 2018, Vol. 3(1), 1-2.

    - Rachidi, M. (2018). Trisomy of Chromosome 21 provides a Genetic Model for the Role of Aneuploidy in Cell Cycle Alterations, Leukemia, Tumors and Cancer   (In Press).

    - Rachidi, M. (2016). Neurogenetic Disorders of Down Syndrome and Potential Pharmacotherapies for Mental Retardation.
    American Journal of Clinical Neurology and Neurosurgery, 2016, Vol. 2, No. 4, 2016, pp. 45-49.

    - Rachidi, M. (2015). Towards the Identification of Genetic Targets for Therapeutics of Intellectual Disability in Down syndrome.
    J.J. Cenetics, 2015.

    - Rachidi, M. and Lopes, C. (2013).  Mental Retardation and Human Chromosome 21 Gene Overdosage: From Functional Genomics and Molecular Mechanisms towards Prevention and Treatment of the Neuropathogenesis of Down Syndrome.
    Handbook of Neurochemistry and Molecular Neurobiology. In Genomics, Proteomics, and the Nervous System, Advances in Neurobiology, Springer Publishers 3rd Ed 2013.

    - Rachidi M., Tetaria C., Lopes C. (2011). “Cell cycle alteration in Down syndrome”. In Berhardt LV. (Ed.), Advances in Medicine and Biology, 2011, Vol. 20. Nova Science Publisher.

    - Rachidi, M. and Lopes, C. (2010). Molecular and Cellular Mechanisms Elucidating the Neurocognitive Basis of Functional Impairments Associated with Intellectual Disability in Down syndrome.
    American Journal of  Intellectual Developmental Disabilities, 2010; 115., 83-112.

    - Rachidi, M. and Lopes, C. (2010). Cell Cycle Alteration in Down syndrome.
    International Journal of Medical and Biological Frontiers, 2010, Volume 16, Issue 3/4,  Nova Science Publishers.

    - Rachidi, M. and Lopes, C. (2009). Gene Expression Regulation in Down syndrome: Dosage Imbalance Effects at Transcriptome and Proteome Levels. Handbook of Down syndrome Research, Edition Nova Science Publishers, Inc., 2009, 55-87

    - Rachidi, M., Delezoide, A-L., Delabar, J.M. and Lopes, C. (2009). A quantitative assessment of gene [removed]QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions.
    International Journal of Developmental Neuroscience, 2009, 27, 393-398.

    - Rachidi, M., Tetaria, C., and Lopes, C. (2008). Trisomy of Human Chromosome 21 and Cell Cycle Control. In Leroy NH., Fournier NT. (Eds.): Cell Cycle Control: New Research, Nova Science Publishers, Inc., 2008, 159-189.

    - Rachidi, M. and Lopes, C. (2008). Mental retardation and associated neurological dysfunctions in Down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways.
    European Journal of Paediatric Neurology, 2008, 12, 168-182.

    - Rachidi, M. and Lopes, C. (2008). Molecular Mechanisms of Mental Retardation in Down syndrome. Rachidi, M. and Lopes, C. (Editors), Nova Biomedical Book: Edition Nova Science Publishers, Inc., 2008, pp 1-94.

    - Rachidi, M., Lopes, C.; C Vayssettes, D J. Smith, E M Rubin, J.M Delabar. (2007). New Cerebellar Phenotypes in YAC Transgenic mouse in vivo Library of Human Down syndrome Critical Region 1.
    Biochemical Biophysical Research Communications, 2007, 364(3), 488-494.

    - Rachidi, M. and Lopes, C. (2007). Molecular Mechanisms of Mental Retardation in Down Syndrome. In Carson MI. (Ed.): Focus on Mental Retardation Research. Nova Science Publishers, Inc. 2007, pp. 77-134.

    - Rachidi, M. and Lopes, C. (2007). Mental retardation in Down syndrome: From gene dosage imbalance to molecular and cellular mechanisms.
    Neuroscience Research, 2007, 59(4), 349-369.

    - Rachidi, M. and Lopes, C. (2006). Differential transcription of Barhl1 homeobox gene in restricted functional domains of the central nervous system suggests a role in brain patterning.
    International Journal of Developmental Neuroscience, 2006, 24(1), 35-44.

    - Rachidi, M., Lopes, C., Delezoide, A.L. and Delabar, J.M. (2006). C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down Syndrome.
    Cytogenetics and Genome Research, 2006, 112(1-2), 16-22.

    - Lopes, C., Delezoide, A.L., Delabar, J.M. and Rachidi, M. (2006). BARHL1 homeogene, the human ortholog of the mouse Barhl1 involved in cerebellum development, shows regional and cellular specificities in restricted domains of developing human central nervous system.
    Biochemical Biophysical Research Communications, 2006, 339, 296-304.

    - Rachidi, M., Lopes, C., Costantine, M. and Delabar J.M. (2005). C21orf5, a new member of dopey family involved in morphogenesis, could participate to neurological alterations and mental retardation in Down syndrome.
    DNA Research, 2005, 12, 203-210.

    - Rachidi, M., Lopes, C., Charron, G., Delezoide, AL., Paly, E., Bloch, B. and Delabar, JM. (2005). Spatial and temporal localization during embryonic and fetal human development of the transcription factor SIM2 in brain regions altered in Down syndrome.
    International Journal of Developmental Neuroscience, 2005, 23, 475-484.

    - Rachidi, M., Lopes, C., Benichou, J.C., Hellio, R. and Maisonhaute, C. (2005). Virus-like particle formation in Drosophila melanogaster germ cells suggests a complex translational regulation of the retrotransposon cycle and new mechanisms inhibiting transposition.
    Cytogenetics and Genome Research, 2005, 111(1), 88-95.

    - Lopes, C., Chettouh, Z., Delabar, J.M. and Rachidi, M. (2003). The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice. Biochemical Biophysical Research Communications, 2003, 305, 915-924.

    - Takamatsu, Y., *Nakagoshi, H., *Rachidi, M., Lopes, C. Nishida, Y. and Ohsako, S. (2002). Characterization of the dCaMKII-GAL4 driver line whose expression is controlled by the. Drosophila Ca²+/calmodulin dependent protein kinase II promoter.
    Cell Tissue Research., 2002, 310(2), 237-252.

    - Lopes, C., Gassanova, S., Delabar, J.M. and Rachidi, M. (2001). The CASK/Lin-2 Drosophila Homologue, Camguk, Could Play a Role in Epithelial Patterning and in Neuronal Targeting.
    Biochemical Biophysical Research Communications, 2001, 284(4), 1004-1010.

    - Lopes, C., Rachidi, M., Charron, G., Chamoun, Z., Dahmane, N., Toyama, K., Chettouh, Z., Vekemans, M., Bloch, B., Delezoide, A.L. and Delabar, JM. (2001). Conservation of the CNS expression pattern of new genes from the Down syndrome chromosomal region-1: human genes and their murine orthologs.
    Cytogenetics and Cell Genetics, 2001, 92(1-2), 1-22.

    - Rachidi, M., Lopes, C., Gassanova, S., Sinet, P.M., Vekemans, M., Attie, T., Delezoide, A.L. and Delabar, J.M. (2000). Regional and cellular specificity of TPRD, the tetratricopeptide Down Syndrome gene, during embryonic development.
    Mechanisms of Development, 2000, 93(1-2), 189-193.

    - Delabar, J.M., Rachidi, M., Lopes, C., Charron, G., Chamoun, Z, Dahmane, N., Toyama, K., Chettouh, Z., Vekemans, M., Bloch, B. and Delezoide, A.L. (2000). Conservation of the CNS expression pattern of new genes from the Down Syndrome Chromosomal Region-1: Human genes and their Murine orthologs.
    European Journal Neuroscience, 2000, 12(Supp 11), 297.

    - Orti, R., Rachidi, M., Viallard, F., Toyama, K., Lopes, C., Taudien, S., Rosenthal, A., Sinet, P.M. and Delabar, J.M. (2000). Characterisation of a novel gene, C21orf6, mapping to a critical region of chromosome 21q22.1 involved in the monosomy 21 phenotype and its murine ortholog.
    Genomics, 2000, 64(2), 203-210.

    - Rahmani, Z., Lopes, C., Rachidi, M. and Delabar, J.M. (1999). Expression of the mnb (dyrk) protein in adult and embryonic mouse tissues.
    European Journal of Human Genetics, 1999, 7(Supp.1), 111.

    - Rachidi, M., Lopes, C., Takamatsu, Y., Ohsako, S., Benichou J.C. and Delabar, J.M. (1999). Dynamic expression pattern of Ca2+/calmodulin-dependent protein kinase II gene in the central nervous system of Drosophila throughout development.
    Biochemical Biophysical Research Communications, 1999, 260(3), 707-711.

    - Lopes, C., Rachidi, M., Gassanova, S., Sinet, P.M. and Delabar, J.M. (1999). Developmentally regulated expression of mtprd, the murine ortholog of tprd, a gene from the Down syndrome chromosomal region 1.
    Mechanisms of Development, 1999, 84(1-2), 189-193.

    - Rahmani, Z., Lopes, C., Rachidi, M. and Delabar, J.M. (1998). Expression of the Mnb (dyrk) protein in adult and embryonic mouse tissues.
    Biochemical Biophysical Research Communications,  1998, 253(2), 514-518.

    - Rachidi, M., Lopes, C. and Benichou, J.C. (1997). Genetical analysis of visual system disorganizer (vid), a new gene involved in normal development of eye and optic lobe of the brain in Drosophila melanogaster. 
    Genetica, 1997, 99, 31-45.

    - Rachidi, M., Lopes, C., Benichou, J.C. and Rouyer, F. (1997). Analyse of period circadian expression in the Drosophila head by in situ hybridization. Journal of Neurogenetics, 1997, 11, 255-263.

    - Rouyer, F., Rachidi, M., Pikielny, C. and Rosbash, M. (1997). A new gene encoding a putative transcritpion factor regulated by the Drosophila circadian clock.
    EMBO Journal, 1997, 16(13), 3944-3954.

    - Haoudi, A., Rachidi, M., Kim, M.H., Champion, S., Best-Belpomme, M. and Maisonhaute, C. (1997). Developmental expression analysis of the 1731 retrotransposon reveals an enhancement of Gag-Pol frameshifting in males of Drosophila melanogaster.
    Gene, 1997, 196 (1-2), 83-93.

    - Fassouane, A., Rachidi, M., Rouffaud, M.A., El-Abbouyi, A. and Nguyen, V.H. (1995). In vitro antifungal activity of Bacillus licheniformis FSJ-2 products against dermatophytes.
    Journal of Mycology and Medicine, 1995, 5, 244-248.

    - Rachidi, M. (1993). The Drosophila visual system: An elaborated building and a powerful model for developmental studies. Biomatec Journal, 1993, 4-5, 2-8.

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    Petra Maresova
    petra.maresova@uhk.cz
    ABSE

    Research Interest: Business Economics, Knowledge Management, Cost Benefit Analysis Method – application in company and in medical device market development, Healthcare, efectivness of medical equipment development. 

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    Kamel Ferrat Crstdla
    Senior Researcher
    Laboratory of Speech Communication
    Research Interest: Berber phonetics, Automatic Speech processing, Speech disorders Acoustic phonetics, Automatic Speech Recognition, Speech Synthesis, Artificial Neural NetworksArabic phonetics
    Algeria
    kamelferrat@yahoo.fr
    ABSE

    Research Interest: Berber phonetics, Automatic Speech processing, Speech disorders Acoustic phonetics, Automatic Speech Recognition, Speech Synthesis, Artificial Neural NetworksArabic phonetics

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    Corrado Cescon
    Polytechnic University of Turin
    Italy
    corrado.cescon@supsi.ch
    ABSE

    Research Interest: Electromyography, muscle fatigue, motor units, innervation zone, anal sphincter, MMG, biofeedback, cervical kinematics, helical axis

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    Paola Saccomandi
    Assistant Professor
    Department of Biomedical Engineering
    university Campus Bio-Medico di Roma
    Italy
    p.saccomandi@unicampus.it
    ABSE

    Research Interest: Since 2008 Paola Saccomandi has been involved in research activities in the fields of biomedical instrumentations and measurements applied to medicine. From 2008 to 2011 she worked under the supervisio of Prof. Sergio Silvestri and Dr. Emiliano Schena in the fied of mechanical ventilation. In particular she worked on development of optoelectronic and fiber optic-based flow sensors, as well as on ventilatory gases humidification. In 2011 she started her main research activity in the field of laser ablation of cancer, with particular regard to pancreatic tumor. She developed a mathematic model aiming to predic effects of laser light o pancreas, in terms of ablated volume and temperature distribution. Since 2012 she has been investigating the field of invasive (fiber optic sensors, thermocouples) and non-ivasive (based on diagnostic images) thermometry for temperature monitoring during laser ablation of tumour. In this activity she is actively collaborating with the team of research of the Institute for Diagnostic and Interventional Radiology of J. W. Goethe Universität Frankfurt am Main, headed by Prof. Thomas J. Vogl. Since 2013 she has been working in the fied of optical characterization of biological tissue, aiming to estimate optical properties of pancreas. She is collaborating with the team of Biophysics Institute J. W. Goethe Universität Frankfurt am Main, headed by Prof. Werner Mäntele. In the framework of laser ablation for the removal of pancreatic cancer, she has participated at the study approved by UCBM Ethics Committee -ComEt UCBM-, Prot. N. 4011/2011. The study aims to treat with laser ablation patients with inoperable pancreatic cancer. Since 2014 she is also involved in the design and development of tactile sensors for robotic artificial prosthetics

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    Mansour Mhaede
    Institute of Materials Science and Engineering
    lausthal University of Technology
    Germany
    mansour.mhaede@tu-clausthal.de
    ABSE

    Research Interest: Characterizing the mechanical properties and corrosion behaviour of biomaterials Mechanical surface treatments (shot peening and ball-burnishing) of metals and alloys. Coatings prior and after mechanical surface treatments. Evaluating the effects of Severe Plastic Deformations (SPD) on the materials. Characteristics Evaluation of surface layer properties (surface roughness, micro-hardness and residual stresses) of metals and alloys. Fatigue, corrosion fatigue and stress corrosion cracking of metals and alloys. Corrosion monitoring by electrochemical techniques. Analytical assessments by SEM and EDX. Analytical assessments by spectrophotometer and atomic absorption

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    Yan Xie
    Queensland University of Technology
    Australia
    y2.xie@qut.edu.au
    ABSE

    Research Interest: Tissue & organ repair and regeneration, Tissue engineering, Wound healing, Clinical medicine, dimensional tissue equivalent models, Novel wound and scar remediation therapies, Chinese herbal medicine, Growth factor/extracellular matrix protein complexes, Pharmaceutical and drugs

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    Sophie Laurent
    Assistant Professor
    Department of General, Organic and Biomedical Chemistry
    University of Mons
    Belgium
    Sophie.LAURENT@umons.ac.be
    ABSE

    Research Interest: Development of new lanthanide complexes for MRI and optical imaging: synthesis, purification (HPLC, flash chromatography) and physicochemical characterization (NMR spectroscopy, mass spectrometry, luminescence, UV-visible, FTIR).  

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    Rajasekharreddy Pala
    Research Associate
    Biomedical Sciences
    Chapman University and University of California Irvine
    USA
    raja.biotech@gmail.com
    ABSE

    Dr. Rajasekharredy Pala is a Nano biotechnologist specialized in the synthesis of various metal and metal oxide nanoparticles with their application as drug delivery agents to the primary cilia. After his post-graduation he was selected for ICMR-Senior Research Fellowship under Biomedical Sciences in 2011 and during this period of his doctoral studies at CSIR-Indian Institute of Chemical Technology, India, he has earned handsome experience on the physical and chemical characterizations techniques of nanoparticles that are enveloped with various biologically active compounds such as protein, lipids and small molecular drugs for their biomedical applications. Dr. Pala working as a research associate in Chapman University and University of California Irvine from 2015.

    Research Interest: Nanomedicine, Hypertension, Cancer, Renal diseases

    URL: https://sites.chapman.edu/cilia/pala-rajasekharreddy/

    Skype ID: raaja.biotech

    List of Publications: 

    Rajasekharreddy Pala, Ashraf M. Mohieldin, Kiumars Shamloo, Rinzhin T. Sherpa, Sarmed H.

    Kathem, Jing Zhou, Zhongyue Luan, Jian-Guo Zheng, Amir Ahsan, and Surya M. Nauli.

    Personalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular

    Hypertension. Nano Letters Article ASAP DOI: 10.1021/acs.nanolett.8b04138

    2. Zeng, Y., Zhu, J., Wang, J., Parasuraman, P., Busi, S., Nauli, S. M., Wáng, Y., Pala,

    Rajasekharreddy, Liu, G. (2018). Functional probes for cardiovascular molecular

    imaging. Quantitative imaging in medicine and surgery, 8(8), 838-852 (co-corresponding

    author).

    3. Pala, Rajasekharreddy., Jamal, M., Alshammari, Q., Nauli, S.M. The Roles of Primary Cilia in

    Cardiovascular Diseases. Cells 2018, 7, 233. (Published as cover page)

    4. Rajasekharreddy Pala, Yun Zeng, Subhaswaraj Pattnaik, Siddhardha Busi, Alomari Nedaa,

    Nauli Surya M, Gang Liu, (2018). Functionalized Silver Nanoparticles for Sensing, Molecular

    Imaging and Therapeutic Applications. Current Nanomedicine, Pages 1 - 17 (17).

    5. Pala Rajasekharreddy, Pathipati Usha Rani, Mattapally Saidulu & Sanjay K. Banerjee (2017).

    Ultra-small silver nanoparticles induced ROS activated Toll-pathway against Staphylococcus

    aureus disease in silkworm model, Materials Science and Engineering: C, 77, 990-1002

    (corresponding author).

    6. Pala Rajasekharreddy, Chao Huang, Siddhardha Busi, Jobina Rajkumari, Ming-Hong Tai, Gang

    Liu (2017). Green Synthesized Nanomaterials as Theranostic Platforms for Cancer Treatment:

    Principles, Challenges and the Road Ahead. Current Medicinal Chemistry, 24, 1-17. Doi.

    10.2174/0929867324666170309124327.

    7. Jobina Rajkumari, Siddhardha Busi, Aneesh Cherukunnel Vasu, Pala Rajasekharreddy (2017),

    Facile green synthesis of baicalein fabricated gold nanoparticles and their antibiofilm activity

    against Pseudomonas aeruginosa PAO1. Microbial Pathogenesis, 107: 261-269.

    8. Rajasekharreddy Pala, Nedaa Alomari, Surya M. Nauli (2017). Primary Cilium-Dependent

    Signaling Mechanisms, International Journal of Molecular Sciences, 18, 2272.

    9. Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T. Sherpa, Rajasekharreddy

    Pala, Kimberly F. Atkinson,William J. Pearce, Lubo Zhang, Surya M. Nauli (2017). Chronic

    Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys.

    Frontiers in Physiology, 8: 677.

    10. Nauli, Surya M., Rajasekharreddy Pala, and Steven J. Kleene (2016). "Calcium channels in

    primary cilia." Current Opinion in Nephrology and Hypertension 25 (5): 452-458.

    11. Pala Rajasekharreddy and Pathipati Usha Rani (2014). Biofabrication of Ag nanoparticles using

    Sterculia foetida L. seed extract and their toxic potential against mosquito vectors and HeLa

    cancer cells. Materials Science and Engineering: C, 39, 203-212.

    12. Pala Rajasekharreddy and Pathipati Usha Rani (2014). Biosynthesis and characterization of Pd

    and Pt nanoparticles using Piper betle L. plant in a photoreduction method. Journal of Cluster

    Science, 25: 1377-1388.

    13. Praveen Kumar Kalavagunta, Rajasekharreddy Pala, Usha Rani Pathipati and Narender Ravirala

    (2014). Identification of β-Naphthol derivatives as novel antifeedants and insecticides-I. Journal

    of Agricultural and Food Chemistry, 62, 6571−6576.

    14. Pala Rajasekharreddy and Pathipati Usha Rani (2012) Nontoxic effects of biologically

    synthesized silver nanoparticles on silkworm, Bombyx mori L. Hexapoda 19 (1): 74–78.

    Pathipati Usha Rani and Pala Rajasekharreddy (2011) Green synthesis of silver-protein (core–

    shell) nanoparticles using Piper betle L. leaf extract and its ecotoxicological studies on Daphnia

    magna. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 389 (1-3): 188-194.

    16. Pathipati Usha Rani, Pala Rajasekharreddy and Kommu Nagaiah (2011). Allelopathic effects of

    (2n-octylcycloprop-1-enyl)-octanoic acid (I) against Four Major Weeds. Allelopathy Journal. 28

    (2) 179-188.

    17. Pala Rajasekharreddy, Pathipati Usha Rani and Bojja Sreedhar (2010). Qualitative assessment of

    silver and gold nanoparticle synthesis in various plants: a photobiological approach. Journal of

    Nanoparticle Research, 12: 1711-1721.

    18. Pala Rajasekharreddy and Pathipati Usha Rani (2010). Toxic properties of certain botanical

    extracts against three major stored product pests. Journal of Biopesticides. 3(3): 586-589.

    19. Pathipati Usha Rani and Pala Rajasekharreddy (2010). Insecticidal activity of (2n-octylcycloprop-

    1-enyl)-octanoic acid (I) against three coleopteran stored product insects from Sterculia foetida

    (L.). Journal of Pest Science, 83(3); 273-279.

    20. Pathipati Usha Rani and Pala Rajasekharreddy (2009). Toxic and antifeedant activities of Sterculia

    foetida (L.) seed crude extract against Spodoptera litura (F.) and Achaea janata (L.). Journal of

    Biopesticides 2(2): 161-164.

    Pathipati Usha Rani and Pala Rajasekharreddy (2013). Plants: The green factories for synthesis

    of nanomaterials” in the book “Nanotechnology Environment” Edited by J.N. Govil. Studium Press

    LLC, USA.

    A method for isolation of an Ortho Quinone Methide intermediate. Pala Rajasekharreddy

    and K.P Kumar and (PCT/IB2015/057628), WIPO publication no. WO/2016/059511.

    • Green synthesis of highly monodispersed silver nanoparticles by plant. P. Usha Rani and Pala

    Rajasekharreddy (File No. 4020/DEL/2012).

    • Novel synthesis of 2-aminobenzothiazolomethyl naphthol derivatives and their

    antifeedant activity. KP Kumar, Pala Rajasekharreddy, V. Narendar & P. Usha Rani (File No

    0802/DEL/2013).


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    Yanmei Tie
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