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Archives of Otolaryngology and Rhinology

ISSN: 2455-1759

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  • Volume/IssueClick here
  • Review ProcessDouble Blind
    • Publication lead time3 - 4 weeks
    • Indexing statusYes; Purview
    • Manuscript Processing ChargesClick here
    • Submission ChargesNo
    • Waiver policy for APCYes
    • Language of Full TextEnglish
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  • Type of LicenseCreative Commons
  • Open AccessYes; Policy
    • Does the author retain unrestricted copyright?Yes
    • Does the author retain publishing rights?Yes
    • Permanent article identifierDOI (Digital Object Identifier)
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Publisher Information

Editor-In-Chief

Peter J Catalano
Peter J Catalano

Tufts University, USA

Email: peter.catalano@steward.org
Tel: +1- 617-999-2973; +1
Fax: +1-617-789-5088

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Executive Editors

Masatsugu Masuda
Associate Professor
Department of Otolaryngology
Kyorin University School of Medicine
Japan
masoeur13@mac.com
AOR

Born

Graduate from Keio University School of Medicine, Tokyo, Japan

Resident in Dept of Otorhinolaryngology, Keio University School of Medicine, Tokyo, Japan

Medical Staff in Otorhinolaryngology, Hiratsuka City Hospital, Kanagawa, Japan

Medical Staff in Otorhinolaryngology, Keiyu Hospital, Kanagawa, Japan

Medical Staff in Otorhinolaryngology, Kawasaki Municipal Hospital, Kanagawa, Japan

Instructor in Otorhinolaryngology, Keio University School of Medicine, Tokyo, Japan

Research staff in Basic Otology Research group (Professor Kaoru Ogawa), Keio University School of Medicine, Tokyo, Japan

Medical staff in department of Otolaryngology of Saiseikai Kanagawa Hospital, Kanagawa, Japan

Post-doctoral fellow in the Division of Otolaryngology-Head and Neck Surgery, University of California, San Diego

Instructor in the Department of Otolaryngology, Kyorin University School of Medicine, Tokyo, Japan

Associate Professor in the Department of Otolaryngology, Kyorin University School of Medicine, Tokyo, Japan

Adjunct Lecturer in the Department of Otolaryngology, Keio University School of Medicine, Tokyo, Japan

Professional website links:

http://www.kyorin-u.ac.jp/univ/graduate/medicine/education/departments/otolaryngology/

http://www.kyorin-u.ac.jp/hospital/clinic/surgery11/index.html

Grant Details:

2015-Present:  

A grant-in-Aid for Scientific Research (C) [15K10761] from Ministry of Education, Culture, Sports, Science and Technology. “Changes of the auditory and equilibrium functions induced by optogenetic control of the stria vascularis function.”

2011-2014:

Grant-in Aid for Young Scientists (B) [23791930] from Ministry of Education, Culture, Sports, Science and Technology. “Artificial synapse formation for the implantable artificial organ of Corti.”

List of Publications:

1    Masuda, M., Goto, F., Hasegawa, T., Matsumoto, J., Kasakura-Kimura, N., Miyama, Y., Saito, K. & Kito, S. Transcranial magnetic stimulation for the treatment of vestibular decompensation. E-BENT, (in press).
2    Watabe, T., Xu, M., Watanabe, M., Nabekura, J., Higuchi, T., Hori, K., Sato, M. P., Nin, F., Hibino, H., Ogawa, K., Masuda, M. & Tanaka, K. F. Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice. Sci Rep 7, 13605, doi:10.1038/s41598-017-13997-7 (2017).
3    Sato, M. P., Higuchi, T., Nin, F., Ogata, G., Sawamura, S., Yoshida, T., Ota, T., Hori, K., Komune, S., Uetsuka, S., Choi, S., Masuda, M., Watabe, T., Kanzaki, S., Ogawa, K., Inohara, H., Sakamoto, S., Takebayashi, H., Doi, K., Tanaka, K. F. & Hibino, H. Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear. Front Mol Neurosci 10, 300, doi:10.3389/fnmol.2017.00300 (2017).
4    Oishi, N., Yamada, H., Kanzaki, S., Kurita, A., Takiguchi, Y., Yuge, I., Asama, Y., Masuda, M. & Ogawa, K. Assessment of hyperacusis with a newly produced Japanese version of the Khalfa hyperacusis questionnaire. Acta Otolaryngol 137, 957-961, doi:10.1080/00016489.2017.1306654 (2017).
5    Masuda, M., Li, Y., Pak, K., Chavez, E., Mullen, L. & Ryan, A. F. The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells. Mol Neurobiol 54, 5414-5426, doi:10.1007/s12035-016-0060-7 (2017).
6    Kasakura-Kimura, N., Masuda, M., Mutai, H., Masuda, S., Morimoto, N., Ogahara, N., Misawa, H., Sakamoto, H., Saito, K. & Matsunaga, T. WFS1 and GJB2 mutations in patients with bilateral low-frequency sensorineural hearing loss. Laryngoscope 127, E324-E329, doi:10.1002/lary.26528 (2017).
7    Masuda, M., Mutai, H., Arimoto, Y., Nakano, A. & Matsunaga, T. A novel frameshift variant of COCH supports the hypothesis that haploinsufficiency is not a cause of autosomal dominant nonsyndromic deafness 9. Biochem Biophys Res Commun 469, 270-274, doi:10.1016/j.bbrc.2015.11.106 (2016).
8        Masuda, M., Matsumoto, J., Nakamura, T., Matsuda, T., Naoyuki, K. & Saito, K. The impact of postoperative antrum pneumatization on hearing outcome after canal wall-down tympanoplasty with softwall reconstruction for cholesteatoma. Abstract for the 10th International Conference on Cholesteatoma,Edinburgh UK. J Laryngol Otol 130, S201-S202, https://doi.org/10.1017/S0022215116006228 (2016).
9    Ryan, A. F., Ikeda, R. & Masuda, M. The regulation of gene expression in hair cells. Hear Res 329, 33-40, doi:10.1016/j.heares.2014.12.013 (2015).
10    Masuda, M. & Kanzaki, J. Cause of idiopathic sudden sensorineural hearing loss: The stress response theory. World Journal of Otorhinolaryngology 3, 42-57, doi:10.5319/wjo.v3.i3.42 (2013).
11    Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1. Dev Biol 372, 68-80, doi:10.1016/j.ydbio.2012.09.002 (2012).
12    Masuda, M., Kanzaki, S., Minami, S., Kikuchi, J., Kanzaki, J., Sato, H. & Ogawa, K. Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 33, 1142-1150, doi:10.1097/MAO.0b013e3182635417 (2012).
13    Masuda, M., Dulon, D., Pak, K., Mullen, L. M., Li, Y., Erkman, L. & Ryan, A. F. Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice. Neuroscience 197, 48-64, doi:10.1016/j.neuroscience.2011.09.033 (2011).
14    Wakabayashi, K., Fujioka, M., Kanzaki, S., Okano, H. J., Shibata, S., Yamashita, D., Masuda, M., Mihara, M., Ohsugi, Y., Ogawa, K. & Okano, H. Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea. Neurosci Res 66, 345-352, doi:10.1016/j.neures.2009.12.008 (2010).
15    Taura, A., Taura, K., Choung, Y. H., Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. Neuroscience 166, 1185-1193, doi:10.1016/j.neuroscience.2009.12.064 (2010).
16    Choung, Y. H., Taura, A., Pak, K., Choi, S. J., Masuda, M. & Ryan, A. F. Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161, 214-226, doi:10.1016/j.neuroscience.2009.02.085 (2009).
17    Masuda, M., Tanaka, K. F., Kanzaki, S., Wakabayashi, K., Oishi, N., Suzuki, T., Ikenaka, K. & Ogawa, K. GFAP aggregates in the cochlear nerve increase the noise vulnerability of sensory cells in the organ of Corti in the murine model of Alexander disease. Neurosci Res 62, 15-24, doi:10.1016/j.neures.2008.05.005 (2008).
18    Masuda, M., Inoue, Y., Tanosaki, R., Kanzaki, S. & Ogawa, K. Development of solitary plasmacytoma in the internal auditory canal and inner ear after allogeneic hematopoietic stem cell transplantation for plasma cell leukemia. Jpn J Clin Oncol 37, 701-703, doi:10.1093/jjco/hym079 (2007).
19    Masuda, M., Nagashima, R., Kanzaki, S., Fujioka, M., Ogita, K. & Ogawa, K. Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation. Brain Res 1068, 237-247, doi:10.1016/j.brainres.2005.11.020 (2006).
20    Fujioka, M., Kanzaki, S., Okano, H. J., Masuda, M., Ogawa, K. & Okano, H. Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res 83, 575-583, doi:10.1002/jnr.20764 (2006).

 </xml> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Century","serif"; mso-ascii-font-family:Century; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Century; mso-hansi-theme-font:minor-latin; mso-font-kerning:1.0pt; mso-ansi-language:EN-US; mso-fareast-language:JA;} </style> http://www.kyorin-u.ac.jp/hospital/clinic/surgery11/index.htmlGrant Details:2015-Present A grant-in-Aid for Scientific Research (C) [15K10761] from Ministry of Education, Culture, Sports, Science and Technology. “Changes of the auditory and equilibrium functions induced by optogenetic control of the stria vascularis function.”2011-2014   Grant-in Aid for Young Scientists (B) [23791930] from Ministry of Education, Culture, Sports, Science and Technology. “Artificial synapse formation for the implantable artificial organ of Corti.”List of Publications:1    Masuda, M., Goto, F., Hasegawa, T., Matsumoto, J., Kasakura-Kimura, N., Miyama, Y., Saito, K. & Kito, S. Transcranial magnetic stimulation for the treatment of vestibular decompensation. E-BENT, (in press).2    Watabe, T., Xu, M., Watanabe, M., Nabekura, J., Higuchi, T., Hori, K., Sato, M. P., Nin, F., Hibino, H., Ogawa, K., Masuda, M. & Tanaka, K. F. Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice. Sci Rep 7, 13605, doi:10.1038/s41598-017-13997-7 (2017).3    Sato, M. P., Higuchi, T., Nin, F., Ogata, G., Sawamura, S., Yoshida, T., Ota, T., Hori, K., Komune, S., Uetsuka, S., Choi, S., Masuda, M., Watabe, T., Kanzaki, S., Ogawa, K., Inohara, H., Sakamoto, S., Takebayashi, H., Doi, K., Tanaka, K. F. & Hibino, H. Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear. Front Mol Neurosci 10, 300, doi:10.3389/fnmol.2017.00300 (2017).4    Oishi, N., Yamada, H., Kanzaki, S., Kurita, A., Takiguchi, Y., Yuge, I., Asama, Y., Masuda, M. & Ogawa, K. Assessment of hyperacusis with a newly produced Japanese version of the Khalfa hyperacusis questionnaire. Acta Otolaryngol 137, 957-961, doi:10.1080/00016489.2017.1306654 (2017).5    Masuda, M., Li, Y., Pak, K., Chavez, E., Mullen, L. & Ryan, A. F. The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells. Mol Neurobiol 54, 5414-5426, doi:10.1007/s12035-016-0060-7 (2017).6    Kasakura-Kimura, N., Masuda, M., Mutai, H., Masuda, S., Morimoto, N., Ogahara, N., Misawa, H., Sakamoto, H., Saito, K. & Matsunaga, T. WFS1 and GJB2 mutations in patients with bilateral low-frequency sensorineural hearing loss. Laryngoscope 127, E324-E329, doi:10.1002/lary.26528 (2017).7    Masuda, M., Mutai, H., Arimoto, Y., Nakano, A. & Matsunaga, T. A novel frameshift variant of COCH supports the hypothesis that haploinsufficiency is not a cause of autosomal dominant nonsyndromic deafness 9. Biochem Biophys Res Commun 469, 270-274, doi:10.1016/j.bbrc.2015.11.106 (2016).8        Masuda, M., Matsumoto, J., Nakamura, T., Matsuda, T., Naoyuki, K. & Saito, K. The impact of postoperative antrum pneumatization on hearing outcome after canal wall-down tympanoplasty with softwall reconstruction for cholesteatoma. Abstract for the 10th International Conference on Cholesteatoma,Edinburgh UK. J Laryngol Otol 130, S201-S202, https://doi.org/10.1017/S0022215116006228 (2016).9    Ryan, A. F., Ikeda, R. & Masuda, M. The regulation of gene expression in hair cells. Hear Res 329, 33-40, doi:10.1016/j.heares.2014.12.013 (2015).10    Masuda, M. & Kanzaki, J. Cause of idiopathic sudden sensorineural hearing loss: The stress response theory. World Journal of Otorhinolaryngology 3, 42-57, doi:10.5319/wjo.v3.i3.42 (2013).11    Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1. Dev Biol 372, 68-80, doi:10.1016/j.ydbio.2012.09.002 (2012).12    Masuda, M., Kanzaki, S., Minami, S., Kikuchi, J., Kanzaki, J., Sato, H. & Ogawa, K. Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 33, 1142-1150, doi:10.1097/MAO.0b013e3182635417 (2012).13    Masuda, M., Dulon, D., Pak, K., Mullen, L. M., Li, Y., Erkman, L. & Ryan, A. F. Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice. Neuroscience 197, 48-64, doi:10.1016/j.neuroscience.2011.09.033 (2011).14    Wakabayashi, K., Fujioka, M., Kanzaki, S., Okano, H. J., Shibata, S., Yamashita, D., Masuda, M., Mihara, M., Ohsugi, Y., Ogawa, K. & Okano, H. Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea. Neurosci Res 66, 345-352, doi:10.1016/j.neures.2009.12.008 (2010).15    Taura, A., Taura, K., Choung, Y. H., Masuda, M., Pak, K., Chavez, E. & Ryan, A. F. Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. Neuroscience 166, 1185-1193, doi:10.1016/j.neuroscience.2009.12.064 (2010).16    Choung, Y. H., Taura, A., Pak, K., Choi, S. J., Masuda, M. & Ryan, A. F. Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161, 214-226, doi:10.1016/j.neuroscience.2009.02.085 (2009).17    Masuda, M., Tanaka, K. F., Kanzaki, S., Wakabayashi, K., Oishi, N., Suzuki, T., Ikenaka, K. & Ogawa, K. GFAP aggregates in the cochlear nerve increase the noise vulnerability of sensory cells in the organ of Corti in the murine model of Alexander disease. Neurosci Res 62, 15-24, doi:10.1016/j.neures.2008.05.005 (2008).18    Masuda, M., Inoue, Y., Tanosaki, R., Kanzaki, S. & Ogawa, K. Development of solitary plasmacytoma in the internal auditory canal and inner ear after allogeneic hematopoietic stem cell transplantation for plasma cell leukemia. Jpn J Clin Oncol 37, 701-703, doi:10.1093/jjco/hym079 (2007).19    Masuda, M., Nagashima, R., Kanzaki, S., Fujioka, M., Ogita, K. & Ogawa, K. Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation. Brain Res 1068, 237-247, doi:10.1016/j.brainres.2005.11.020 (2006).20    Fujioka, M., Kanzaki, S., Okano, H. J., Masuda, M., Ogawa, K. & Okano, H. P
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Editorial Board Join as Editor

Fang-Lu Chi
Professor
Department of Otolaryngology
Fudan University
PR China
chifanglu@126.com
AOR

Research Interest: Neurotology and lateral skull base surgery, Inner ear hair cell regeneration, Cochlear implantation research, Vestibular vertigo.

More Info.
Wen-Hung Wang
Assistant Professor
Department of Occupational Therapist
Fu-Jen Catholic University
Taiwan
evan_travel@hotmail.com
AOR

Research Interest: Head and Neck Cancer, Cochlear Implant, Narrow-band Imaging Endoscopy.

More Info.
Dehui Wang
Associate Professor
Deptaprtment of ENT, Otolaryngology
Fudan University
PR China
wangdehuient@sina.com
AOR

Research Interest: 1. American Journal of otolaryngology,2. Rhinology, 3. Acta of otorhinolaryngology,4. laryngoscope, 5. Otorhinolaryngology.


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Li Ching Lin
Assistant Professor
Department of Radiation Oncology
Chi-Mei Foundation Medical Center
Taiwan
8508a6@mail.chimei.org.tw
AOR

Research Interest: Head and Neck cancers, Radiotherapy, Side effects of Radiotherapy.

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Giannis Vlastos
Department of Otolaryngology
Latriko Childrens Hospital
Greece
giannisvlastos@yahoo.gr
AOR

Research Interest: Paediatrics,Journal of Science and Technology, ENT, Embiodiagnostics.


More Info.
Jong Lyel Roh
Professor
Department of Otolaryngology-Head and Neck Surgery
University of Ulsan College of Medicine
Korea
rohjl@amc.seoul.kr
AOR

Research Interest: I. Head and neck oncology II. Organ preservation by minimally invasive surgery, laser and robotic surgery III. Oncologic research: chemo- & radio-resistant mechanism, ROS, cancer metabolism, p53 reactivation, ceramide metabolism IV. Quality of Life of head and neck cancer patients  V. Laryngology.

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Qian-Hui Qiu
Department of Otorhinolaryngology
Guangdong General Hospital
China
qiuqianhui@hotmail.com
AOR
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Katsumi Doi
Professor
Department of Otolaryngology
Kinki University
Japan
kdoi@med.kindai.ac.jp
AOR

Research Interest: Otology”, “neuro-otology”,“audiology”, “middle ear surgery”, and “inner ear.


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Mu-Kuan Chen
Professor
Department of Head and Neck Society Changhua Christian Hospital
Taiwan
170780@cch.org.tw
AOR

Research Interest: Head and neck surgery and treatment ,Medical Imaging ,Biostatistics ,Biochemistry.

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Zhengcai Lou
Professor
Department of Otorhinolaryngology
Wenzhou Medical University
China
louzhengcai@163.com
AOR

Research Interest: Tympanic membrane regeneration, and  laryngopharyngeal reflux

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Wang Fusen
Researcher
Department of Otolaryngology
Baoan Peoples Hospital of Shenzhen City
China
wafus@163.com
AOR

Research Interest: Inner ear, inner ear pathology .

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Laszlo Makra
Associate Professor
Department of Otolaryngology
University of Szeged
Hungary
makra@geo.u-szeged.hu
AOR

Research Interest: Ragweed, pollen climatology, pollen transport, pollen concentration forecast, pollen statistics.

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Bing Yan
Assistant Professor
Department of Otolaryngology Head and Neck Surgery
Xiamen University
China
yanbing_west@163.com
AOR

Research Interest: Head and neck tumor, Raman spectroscopy, diagnosis, treatment.

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Werner Heppt
Professor
Department of Otorhinolaryngology
Karlsruhe University
Germany
wheppt@web.de
AOR

Research Interest: Rhinoplasty, Facial Plastic and Reconstructive Surgery, Sinus Surgery.

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Junan Li
Research Scientist
Department of Chemistry
The Ohio State University
USA
li.225@osu.edu
AOR

Research Interest: Cancer genetics, tumor suppressor, structure, genetic alteration, chemo prevention.


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