Research Interest: Regulation of extracellular matrix genes and growth factors by potential anti-skin aging, anti-carcinogenic or wound repair agents in normal or cancer cells:Area of Expertise: Biochemistry and Cell/Molecular Biology; Biotechnology: Cell culture, Gene Regulation (protein, mRNA, promoter levels), Extracellular matrix (collagen, matrixmetalloproteinases, elastin, fibrillin), Growth factors/cytokines (tranaforming growth factor-b, interleukins), Oxidative Stress/Reactive Oxygen species, Antioxidants, Apoptosis, Toxicity, Angiogenesis/Metastasis.
Research Interest: Studying the pathogenic process
in betanodavirus and iridovirus infection in grouper GF-1 and larval grouper
fish systems. His laboratory pioneered the use of grouper model to study
betanodavirus in vivo on brain damaged, which as a model.
Research Interest: Gentics; Tree Genetic
Improvement; Plant Biotechlology
Research Interest: Obesity, metabolic syndrome, diabetes type 2,dyslipidemia,hypertension.
Research Interest: A versatile biotechnologist with research experience
ranging from searching for novel microbial enzymes using classical and
metagenomic approaches, genetic engineering to tailor them for specific
applications, fermentation, downstream processing and their biotechnological
application. Biotechnological applications range from developing “Green
Chemistry technologies”/processes, developing antimicrobial systems, and
systems/and or products for preventing, monitoring and therapy of oxidative
stress related human diseases (cancer, cardiovascular, respiratory,
atherosclerosis, diabetes, neurodegenerative diseases).
Research Interest: Wheat genetic engineering for resistance to
Fusarium pathogens and tolerance to abiotic stresses, Molecular interaction
between wheat and Fusarium pathogens Recombinant antibodies and bio-agents
against Fusarium pathogens and mycotoxins
Research Interest: With a combination of molecular
biology, biochemistry, cell biology, nutrition metabolism,transgenic/knockout
mice model, I aim to uncover the complex molecular programs that regulates
physiological or pathological biological pathways, such as cell commitment,
cell metabolism, embryonic development, brain development, nutrition
regulation, and the pathological mechanisms of human metabolic diseases, such
as obesity, diabetes and neurological disease..
Research Interest: Characterize, evaluate and utilize the genetic diversity of the G. max and G. soja for soybean breeding
Research Interest: Neurogenesis. Screening the leading chemical
to stimulate the neurogenesis after CNS, diseases, including: Stroke, Multiple
sclerosis, Alzheimers disease et al. Brain tumor. To study the oncogenesis
mechanisms of mellablastoma and glioblastoma.At the same time, to screen the
inhibitor of Sonic hedgehog pathway to treat the brain tumor.
Research Interest: Green materials processing, surface coating, nanomaterials, energy materials and biomaterials
Research Interest: Production of monoclonal and
polyclonal antibodies Microbiology and Immunology Development of biomedical
protein chips Development of mmunochromatographic
strip with nano-gold particle technique Immunosensing analysis technique:
Surface plasmon resonance (Optical sensor) and Quartz crystal microbalance
Research Interest: Designing and preparing new nanobiomaterials, Characterizing physical and chemical
properties, biocompatibility and bioactivity of the nanobiomaterials
Biomedical applications of Nanotechnology, Nano Particulate Drug Delivery
systems, Antibody mediated drug delivery systems, Nano-Nutraceuticals and Nano
dispersed Systems, and educational research
Research Interest: Polymeric Biomaterials and Green Materials: -Synthesis and Characterization, Surface Modification, and Patterning (soft and dip-pen lithography) and Polymers processing, Synthesis of Polyurethanes/Polyesters and Bio-based resins. Nanomaterials and Energy Materials: Polymer-HA or Polymer-CNT Nanocomposites, Synthesis of Nanofibers and Nanoparticles for cancer drug delivery, Chemical modification of Nanodiamond particles and Metallization of CNTs, Polymeric and silica Nanorods as reinforcing fillers for dental restoration materials for flowable composites), Polymer/graphene composite materials and Polymer/polyoxometalate composites for energy applications. Tissue Engineering/ Drug Delivery: Polymeric 3D-Nanofibrous Scaffolds for Bone, Vascular, Neural and Dental, Salivary glands and multifunctional nanoparticles for lung cancer drug and growth factor delivery, Nasal/mucosal delivery of therapeutics), Electrospining and Force-spinning techniques for polymer and ceramic composite nanofabrication. Additive bio-manufacturing and We-laid Process for biomaterials/scaffolds of complex tissues and interfaces. Characterization of Materials: Microscopic and Spectroscopic characterization (SEM, AFM, FT-IR, XPS), mechanical properties characterization (Tensile, compression, dynamic mechanical (DMA) and nanoindentation), thermal properties (TGA, DSC, TMA) and Rheological characterization of polymeric biomaterials, nanomaterials and hybrid polymer/inorganic composites and in vitro Cell Studies for biocompatibility and toxicity. In Vitro Evaluation of nano-structured materials/ nanodiamond wear-debris from orthopedic joint implants: Nanoscaled wear-debris isolation from Hip and knee Simulator (AMTI) and its inflammatory effect evaluation.
Research Interest: Methodology of solid phase
peptide synthesis and synthetic peptides with bioactivity
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