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Global Journal of Cancer Therapy

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Role of tumor heterogeneity in drug resistance

Published On: July 20, 2017 | Pages: 032 - 033

Author(s): Dhruv Kumar*
Cancer is a leading cause of death in men worldwide and the major cause of cancer related death is drug resistance. ...
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MEK Inhibitors in Combination with Immune Checkpoint Inhibition: Should we be Chasing Colorectal Cancer or the KRAS Mutant Cancer

Published On: May 26, 2017 | Pages: 030 - 031

Author(s): Julius Strauss*
In the past few years, immunotherapy, particularly immune checkpoint inhibitors, have redefi ned standard of care cancer treatment for numerous malignancies. However, despite the wealth of promising data and great enthusiasm, the vast majority of cancer patients still fail to respond to these therapies as single agents. ...
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Angiosarcoma of the Scalp and Face: A Hard to Treat Tumor

Published On: April 15, 2017 | Pages: 026 - 029

Author(s): Jmour Omar*, Kochbati Lotfi , Ghith Sahar and Benna Farouk
Cutaneous angiosarcoma is a rare and aggressive malignant tumor of vascular origin. Multimodality treatment including surgery, radiotherapy and chemotherapy should be used according to age and local spread. Prognosis is poor with a 5-year survival of 10-15%. We report the case of an angiosarcoma of the scalp and face treated with sequential contact radiotherapy and ...
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The Promise of Disease Management in Greece

Published On: March 30, 2017 | Pages: 018 - 025

Author(s): Konstantinos Stamatiou, Richard Lacroix, Eleni Almpani, Konstantinos Katsanos, Georgios Tzitzikos and Maria Saridi*
Background: Disease Management (DM) is an approach to health care that coordinates resources across the entire health care delivery system and throughout the course of a disease. ...
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Abrikossoff’s Tumour Mimicking a Neoplastic Tumour of the Breast: A Case Report

Published On: March 20, 2017 | Pages: 015 - 017

Author(s): Alassiri A*, Al Ali A, Vaysse C, Escourrou G, Vinet B and Rimailho J
Introduction: Granular cell tumours (GCT), also known as Abrikossoff’s tumours, are rare, and occur in the breast in approximately 5-6% of the cases these tumours are usually benign with only 1% of malignancy. ...
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The Role of Decavanadate in Anti- Tumour Activity

Published On: March 11, 2017 | Pages: 012 - 014

Author(s): M Aureliano*
Decavanadate compounds were described to be involved in a variety of biological activities and responses such as anti-virus, anti-bacterial and anticancer. While the mechanisms of action of the antiviral and anti-bacterial activities are better understood, the same does not go for the anti-tumour activity. ...
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Diagnosing HPV-Related Oropharyngeal Cancers: The Need to Speak a Common Language

Published On: March 07, 2017 | Pages: 008 - 011

Author(s): Daniela Russo#, Francesco Merolla#, Gennaro Ilardi*, Silvia Varricchio, Danila Caroppo, Virginia Napolitano, Massimo Mascolo and Stefania Staibano
Oral cavity squamous cell cancer (OSCC) and Oropharynx squamous cell carcinoma (OPSCC) are the most frequent forms of Head and Neck Cancers (HNCs) [1]. About 300,000 new cases of oral cancers are being counted yearly worldwide, having registered an increase of incidence of 225% in U.S.A. ...
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Is it Time for the Introduction of Colostomy Free Survival in Rectal Cancer Patients

Published On: February 28, 2017 | Pages: 004 - 007

Author(s): Mostafa El Haddad*
The rectum is considered the straight part of the bowel although it’s not straight with at least three folds. Sometimes defi ned as the last 12 cm of the large bowel other consider it as the last 15 cm. Surgeons mark it starting at the anorectal ring, anatomist use the dentate line, more consensus and agreements is needed for the rectum as a structure. ...
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Primary Spindle Cell Rhabdomyosarcoma of Prostate: A Case Report with Review of Literature

Published On: February 10, 2017 | Pages: 001 - 003

Author(s): Ram Nawal Rao*, Sanjay Kannaujia and Paramita Paul
Primary spindle cell rhabdomyosarcoma of the prostate is an uncommon variant of embryonal rhabdomyosarcoma seen in pediatric age group mostly during infancy and childhood. Rhabdomyosarcoma (RMS) arising from prostate predominantly presents obstructive urinary symptoms. ...
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