Samy I. McFarlane
State University of New York, Downstate Medical Centre, Brooklyn, New York, USA
Malgorzata Gabriela WASNIEWSKA
University of Messina, Italy
Dr May Ng MBBS (Hons) FHEA FRCPCH MSc LLM PhD
Dr May Ng holds a dual accreditation specialist qualification in General Paediatrics and Paediatric Endocrinology & Diabetes. She is based in Southport and Ormskirk NHS Trust and is the Associate Medical Director. She was previously Clinical Director for Paediatrics from 2012-2016. She has an Honorary Senior Lecturer position at the Institute of Translational Medicine, University of Liverpool. She completed her undergraduate degree under full scholarship in Sydney, Australia and undertook her paediatric training in Australia and in the United Kingdom (UK). She was the recipient of the UK Medical Research Council Fellowship in 2006 and completed further training to obtain a Masters and PhD degree in paediatric endocrinology and diabetes. Dr Ng also holds a Master of Laws degree and is active in medicolegal work.
Dr Ng has held over £300,000 in research grants and is an active researcher in paediatric endocrinology and diabetes. She has produced a book chapter and over 100+ publications (50 peer reviewed research papers, 45 as first/senior author) including three Cochrane reviews and has presented at more than 100+ scientific meetings.
Research Interest: puberty, thyroid, diabetes , adrenal
PROFESSIONAL MEMBERSHIPS AND ROLES:
Fellow of the Royal College of Paediatrics and Child Health (FRCPCH)
Fellow of the Higher Education Academy (FHEA)
Member of the European Society of Paediatric Endocrinology (ESPE)
Committee member of European Society of Paediatric Endocrinology Online Learning
Member of the National Institute of Clinical Excellence (NICE) Adoption and Impact Programme Reference Panel
Member of the National Steering Group for Children and Young People’s Diabetes Peer Review
Diabetes Officer of the British Society of Paediatric Endocrinology and Diabetes (BSPED)
Assessor for the Royal College of Paediatrics and Child Health ST7/START
Committee Member of the RCPCH Paediatricians in Medical Management
RCPCH CSAC Training Advisor for Endocrinology and Diabetes
CCST, Certificate of Completion of Specialist Training: (1) General Paediatrics and (2) Paediatric Endocrinology and Diabetes, General Medical Council UK
FRCPCH, Royal College of Paediatrics and Child Health, UK
DCH, Royal College of Paediatrics and Child Health, UK
FHEA, Fellow of the Higher Education Academy, UK
MBBS (Honours) University of Sydney, Australia
Master of Medical Science (Child Health, Diabetes and Endocrinology) University of Liverpool
PhD (Child Health) University of Liverpool
Master in Laws , University of Liverpool
Winner of 2015 Diabetes Quality in Care (QiC) award
Finalist Commended 2017 Diabetes Team of the year Diabetes Quality in Care (QiC) award
Pride Awards 2015 Team of the Year Southport & Ormskirk NHS Trust
Highly Commended Diabetes Team of the Year 2015 BMJ awards
Finalist HSJ Clinical Leader of the year 2015
Finalist in the UK Asian Woman of Achievement Award
Newborn Appeal Grant 2011
Best Research Abstract Award 2010 BSPED UK
Newborn Appeal Grant 2007
MRC Fellowship 2006 Medical Research Council, UK
University Prize for Paediatrics, University of Sydney, Australia
Number of Publications: 50
1. Ng SM, Turner MA, Avula S. Ultrasound measurements of thyroid gland volume at 36 weeks corrected gestational age in extreme preterm infants born before 28 weeks gestation. European Thyroid Journal 2017.
2. Apperley L, Ng SM. Socioeconomic Deprivation, Household Education and Employment are Associated With Increased Hospital Admissions and Poor Glycemic Control in Children With Type 1 Diabetes Mellitus. Review of Diabetic Studies 2017
3. Ng SM. Digital Footprints: Steps towards transformation in paediatric diabetes. Journal of MHealth 2017, March ow.ly/g6Um30aYCZU
4. Ng SM, Stepien K. Glucocorticoid replacement regimens in the treatment of 21-hydroxylase deficiency congenital adrenal hyperplasia (Protocol) published Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No CD012517. DOI: 10.1002/14651858.CD012517
5. Ng SM, Edge J. Hyperglycaemic Hyperosmolar State (HHS) in children: A practical guide to management. Paediatrics and Child Health Journal 2017 http://dx.doi.org/10.1016/j.paed.2017.01.002
6. Ng SM, Soni A, Didi M. Neonatal Pituitary-Thyroid Axis Dysregulation with Combined Thyroid Hormone and Thyrotropin Resistance in Infant with Trisomy 21 and Maternal Subclinical Hypothyroidism. J Neonatal Biol 2016 5:4 DOI: 10.4172/2167-0897.1000243
7. Ng SM, Agwu JC, Dwan K. A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children. Arch Dis Child 2016 :1–7. doi:10.1136/archdischild-2015-308925
8. Ng SM, Turner M. The Importance of Risk Stratification and Management of Newborn Babies of Women with a History of Graves’ disease. Int J Clin Endocrinol Metab 2016, 2(1): 001-004
9. Soni A, Agwu JC, Kershaw M, Edge J, Wright N, Ng SM. Management of children with type 1 diabetes during illness: a national survey. Postgrad Med J 2015 doi:10.1136/postgradmedj-2015-133786
10. Ng SM, Vizard M. The great enabler: how technology is helping to improve patient outcomes in paediatric diabetes. British Journal of Diabetes and Vascular Disease 2015;15:86-88
11. Soni A, Ng SM. Type 1 and Type 2 diabetes in children and young people: updated NICE guidance. Practical Diabetes 2015;32:281-282
12. Ng SM. Improving patient outcomes with technology and social media in paediatric diabetes. BMJ Quality Improvement Reports 2015; 4(1) DOI:10.1136/bmjquality.u209396.w3846 (1)
13. Ng SM, Watson G, Turner MA, Newland P and Weindling AM. Do maternal factors influence neonatal thyroid status in the extreme premature infant? The Journal of Maternal-Fetal & Neonatal Medicine 2014:26:1-11.
14. Agwu C, Ng SM, Edge DA, Wright. Care of children and young people with diabetes who require surgery. Diabetes Care for Children and Young People 2014:3:106-110
15. Ng SM, Soni A. Intensive diabetes management and goal setting are key aspects of improving metabolic control in children and young people with Type 1 diabetes mellitus. World Journal of Diabetes 2014: 5(6): 877-881 DOI: http://dx.doi. org/10.4239/wjd.v5.i6.877
16. Ng SM, Finnigan L, Connellan L, Caitriona Kerinan, Coward S. Improving paediatric diabetes care with the use of an integrated paediatric electronic diabetes information management system and routine uploading of blood glucose meters and insulin pumps in outpatient clinics. Archive of Disease in Childhood 2014; 99:1059 doi:10.1136/archdischild-2014-307021
17. Ng SM, Mariguddi S, Coward S, Middleton H. Successful implementation of a paediatric community home nursing service as a model of service delivery in acute paediatric care. British Journal of Nursing 2014: 23 (4):209-212.
18. Ng SM, Turner MA, Watson G, Victor S, Isherwood DM, Newland P, Didi M and Weindling AM. Is dopamine an iatrogenic disruptor of thyroid and cortisol function in the extremely premature infant? Advances in Endocrinology 2014; DOI:http://dx.doi.org/10.1155/2014/973184
19. Soni A, Shaw EJ, Natarajan A, Ng SM. Children with Type 1 Diabetes mellitus developing concurrent autoimmune disease are not at risk of worsening metabolic control or growth impairment. Practical Diabetes 2014: 31(6):243-246
20. Ng SM, Turner MA, Didi M, Parkes L, Tietze A, Atkinson J, Sluming V and Weindling AM. Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings from the TIPIT study. Pediatric Radiology 2014:44 (8):987-96
21. Ng SM, Balmuri S. Review of insulin treatment in stress related hyperglycaemia in children without pre-existing diabetes. Acta Paediatrica 2013 doi:10.1111/apa.12442
22. Ng SM, Turner MA, Victor S, M Didi, C Gamble, D Manning, R Gupta, P Settle. P Newland and Weindling AM. An explanatory randomised placebo-controlled trial of thyroxine supplementation in extreme preterm Infants < 28>
23. Murphy A, Martin P, Jukka C, Menon A, Ng SM. Recurrent primary paediatric herpetic whitlow of the big toe. BMJ Case Reports 2013 doi:10.1136/bcr-2013-008598
24. Murphy C and Ng SM. Institution of multiple daily insulin regimen compared with twice daily pre-mixed insulin regimen for children with Type 1 Diabetes Mellitus. American Journal of Clinical Medicine Research 2013 1 (1). doi: 10.12691/ajcmr-1-1-2
25. Ng SM, Drury JA, Turner MA, M Didi, Victor S, Paul Newland, Weindling AM. A Novel Method of Collection of Saliva for Estimation of Steroid Levels in Extremely Premature Infants. Acta Paediatrica 2013:102 (4): 356-9
26. Gangadharan A, Hanumanthaiah H, Ng SM. The Use of Iodine as First Line Therapy in Graves' Disease Complicated with Neutropenia at First Presentation in a Paediatric Patient. British Journal of Medicine and Medical Research, 3(2): 324-328, 2013
27. Hanumanthaiah H, Gangadharan A, Ng SM. Continuous insulin infusion therapy for acute stress hyperglycemia secondary to asthma exacerbation in a paediatric patient. Journal of Diabetes Research and Clinical Metabolism 2012: http://dx.doi.org/10.7243/2050-0866-1-19
28. Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M. Multivariate analysis of factors that affect neonatal screening thyrdois stimulating hormone. Journal of Pediatric Endocrinology and Metabolism 2011, 24: 727-732
29. Hussain M, Cheri J, Khalid M, Matouk Z, Ng SM, Chanderasekaran S, Didi M, Blair J. Growth monitoring still has a place in selected populations of children. BMJ Case Reports 2011; doi:10.1136/bcr.01.2010.2640
30. Ng SM, Weindling MA. The impact of networks on clinical trials in the United Kingdom . Trials 2009, 10:100
31. Ng SM, Turner MA, Gamble C, M Didi, Victor S, Malamateniou C, Parkes L, Tietze A, Gregory L,Sluming V, Abernethy L and Weindling AM. TIPIT: A Randomised Controlled Trial of Thyroxine in Preterm Infants under 28 weeks Gestation: Magnetic Resonance Imaging and Magnetic Resonance Angiography Protocol. BMC Pediatrics 2008, 8:26
32. Ng SM. Hypothyroxinemia of prematurity: cause, diagnosis and management. Expert Review of Endocrinology & Metabolism 2008, 3: 453-462
33. Ng SM, Dhullipala A, Weindling AM. High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism. Cochrane Database of Systemic Reviews 2008, Issue 1
34. Ng SM, Turner MA, Gamble, Didi M, Victor S, Weindling AM. TIPIT: A Randomised controlled trial of thyroxine in preterm infants born under 28 weeks gestation. Trials 2008, 9: 17
35. Ng SM, Wong SC, Isherwood DM, Didi M. Biochemical severity of thyroid ectopia in congenital hypothyroidism demonstrates sexual dimorphism. European Journal of Endocrinology 2007, 156: 49-53
36. Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M. There is a delay in screening premature infants for congenital hypoithyroidism. Archives of Disease in Childhood Fetal Neonatal Ed 2006, 91: F465-466
37. Ng SM, May JE, Emmerson AJB. Continuous insulin infusion in hyperglycemic ELBW infants: An evaluation of treatment response. Biology of the Neonate 2005, 4: 269-272
38. Ng SM, Kumar Y, Cody D, Didi M and Smith CS. The gonadotrophins response to GnRH test is not a predictor of neurological lesion in girls with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism 2005, 18: 849-852
39. Ng SM, Wong SC, Isherwood DM, Smith CS, Didi M. Multivariate analysis on factors affecting suppression of thyroid stimulating hormone in treated congenital hypothyroidism. Hormone Research 2004, 20: 245-251
40. Wong SC, Ng SM, Didi M. Children with congenital hypothyroidism are at risk of adult obesity due to early adiposity rebound. Clinical Endocrinology 2004, 61: 441-6
41. Ng SM, Wong SC, Didi M. Head circumference and linear growth during the first 3 years in treated congenital hypothyroidism in relation to aetiology and initial biochemical severity. Clinical Endocrinology 2004, 61: 155-9
42. Chalameau M, Hadjiaathanasiou C, Ng SM, Cassio A, Mul D, Cisternino M, Partsch CJ, Theodoris C, Didi M, Cacciari E, Oostdijk W, Borghesi A, Sippell WG, Breart G, Brauner R. How to select girls with precocious puberty for brain imaging? An evidence based approach: EUROPUB study. A multicentre trial. Journal of Pediatrics 2003, 143: 445-450
43. Ng SM, Jones AP. Drug therapies for reducing gastric acidity in people with cystic fibrosis. Cochrane Collaboration, Cochrane Library 2003, Issue 2
44. Ng SM, Kumar Y, Cody D, Didi M and Smith CS. Cranial MRI scans are indicated in all girls with central precocious puberty. Archives of Disease in Childhood 2003, 88: 414-418
45. Cody D, Ng SM, Didi M and Smith CS. The differing outcomes of hyperthyrotropinemia. Journal of Paediatric Endocrinology and Metabolism 2003, 16: 375-378
46. Ng SM, Khurana R, Hughes U, Manning D. Is prolonged use of computer games a risk factor for deep venous thrombosis in children? Clinical Medicine 2003, 6: 593-594
47. Ng SM, Toh EM and Sherrington CA. Clinical predictors of abnormal computed tomography scans in paediatric head injury. Journal of Paediatrics and Child Health 2002, 38: 388-392
48. Ng SM, Ariffin WA, Lin HP, Chan LL and Chin YM. Clinical features and treatment outcome of children with myeloid antigen coexpression in B-lineage acute lymphoblastic leukemia. Journal of Tropical Paediatrics 2000, 46: 73-78
49. Ng SM, Lin HP, Ariffin WA, Lam SK and Chan LL. Age, sex, hemoglobin and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol. Journal of Tropical Paediatrics 2000, 46: 338-343
50. Ng SM, Ariffin WA, Lin HP and Chan LL. Presenting features and treatment outcome of 78 Malaysian children with neuroblastoma. Southeast Asian Journal of Tropical Medicine and Public Health 1999, 30: 149-153
Research Interest: Tuberculosis, hospital
infections, HIV, pediatric infectious Disease
Research Interest: Endocrinology, endocrine
disorders, developmental endocrinology, endocrine pathophysiology/issues,
endocrine disorders complications treatment/management.
Research Interest: Diabetes experimental and clinical and gastroenterology and neuroendocrine tumors
Research Interest: Physiology and pharmacology of
nociceptors by means of capsaicin to open new horizons for development nociceptor
targeted analgesic/anti-inflammatory agents and to reveal sensory-efferent dual
functions of capsaicin-sensitive nociceptors
Research Interest: Diabetic foot, cutaneous
complication of diabetes, lipodystrophy, cutaneous manifestation of thyroid
diseases, Cushing disease, adrenal insufficiency, and adrenal hyperplasia.
Research Interest: Primary: Kidney (patho-)physiology Secondary: Diabetes mellitus, oxidative stress, ion transport
Research Interest: Endocrinology, diabetes,
obesity, genetics, children
Health Sciences,Medicine,Immunology, Allergology and Rheumatology
Research Interest: His research has concentrated on how physical, environmental, and emotional stress affects the hormonal responses of the endocrine system; in particular, focusing on dysfunctions and dis-regulations that develop in the system from stress exposure, that ultimately can compromise physiological responses and adaptations
Research Interest: Aldosterone, mineralocorticoids, mineralocorticoid receptor, gene expression, miRNAs, animal models, microarrays, renin-angiotensin system, steroid hormones, nuclear receptors, hypertension, intracellular signaling.
Research Interest: Prostate Cancer, Molecular
Epidemiology, Pharmacogenomic studies, Metabolic syndrome, Endocrine-Related
Cancer, Urolithiasis, Andrology, Male Erectile dysfunction
Research Interest: Diabetes, transplantation, pancreatic islets culture, influence of
microorganism on onset of the diabetes, human microbiom.
Research Interest: Thyroid disease and in
particular thyroid nodules and thyroid cancer, as well as postgraduate medical
Research Interest: Menopause and oestrogen
replacement therapy (ERT) Metabolic syndrome and metabolic effects of estrogens
Phytoestrogens, SERM and Endocrine Disruptors Polycystic ovary syndrome (PCOS) Polymorphisms
of the oestrogen receptor geneAnti-inflammatory and anti-atherogenic properties
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