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International Journal of Clinical Endocrinology and Metabolism

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Journal Information
  • Volume/IssueClick here
  • Review ProcessDouble Blind
    • Publication lead time3 - 4 weeks
    • Indexing statusYes; Purview
    • Manuscript Processing ChargesClick here
    • Submission ChargesNo
    • Waiver policy for APCYes
    • Language of Full TextEnglish
    • Full-text formats availablePDF, HTML
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  • Type of LicenseCreative Commons
  • Open AccessYes; Policy
    • Does the author retain unrestricted copyright?Yes
    • Does the author retain publishing rights?Yes
    • Permanent article identifierDOI (Digital Object Identifier)
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Publisher Information

Editor-In-Chief

Samy I. McFarlane
Samy I. McFarlane

State University of New York, Downstate Medical Centre, Brooklyn, New York, USA

Email: Samy.McFarlane@downstate.edu
Tel: 718-270-3711
Fax: 718-270-1324

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Malgorzata Gabriela WASNIEWSKA
Malgorzata Gabriela WASNIEWSKA

University of Messina, Italy

Email: wasniewska@yahoo.it
Tel: +393286522425
Fax: +390902212134

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Executive Editors

Sze May Ng
Consultant Paaediatric Endocrinologist , Honorary Senior Lecturer
Southport and Ormskirk Hospitals NHS Trust
University of Liverpool
United Kingdom
may.ng@nhs.net
IJCEM

Dr May Ng MBBS (Hons) FHEA FRCPCH MSc LLM PhD

Dr May Ng holds a dual accreditation specialist qualification in General Paediatrics and Paediatric Endocrinology & Diabetes. She is based in Southport and Ormskirk NHS Trust and is the Associate Medical Director. She was previously Clinical Director for Paediatrics from 2012-2016.  She has an Honorary Senior Lecturer position at the Institute of Translational Medicine, University of Liverpool. She completed her undergraduate degree under full scholarship in Sydney, Australia and undertook her paediatric training in Australia and in the United Kingdom (UK). She was the recipient of the UK Medical Research Council Fellowship in 2006 and completed further training to obtain a Masters and PhD degree in paediatric endocrinology and diabetes. Dr Ng also holds a Master of Laws degree and is active in medicolegal work.

Dr Ng has held over £300,000 in research grants and is an active researcher in paediatric endocrinology and diabetes. She has produced a book chapter and over 100+ publications (50 peer reviewed research papers, 45 as first/senior author) including three Cochrane reviews and has presented at more than 100+ scientific meetings.

Research Interest: puberty, thyroid, diabetes , adrenal

URL: www.paedsdoc.co.uk

PROFESSIONAL MEMBERSHIPS AND ROLES:

Fellow of the Royal College of Paediatrics and Child Health (FRCPCH)

Fellow of the Higher Education Academy (FHEA)

Member of the European Society of Paediatric Endocrinology (ESPE)

Committee member of European Society of Paediatric Endocrinology Online Learning

Member of the National Institute of Clinical Excellence (NICE) Adoption and Impact Programme Reference Panel

Member of the National Steering Group for Children and Young People’s Diabetes Peer Review

Diabetes Officer of the British Society of Paediatric Endocrinology and Diabetes (BSPED)

Assessor for the Royal College of Paediatrics and Child Health ST7/START

Committee Member of the RCPCH Paediatricians in Medical Management

RCPCH CSAC Training Advisor for Endocrinology and Diabetes


PROFESSIONAL QUALIFICATIONS:

CCST, Certificate of Completion of Specialist Training: (1) General Paediatrics and (2) Paediatric Endocrinology and Diabetes, General Medical Council UK

FRCPCH, Royal College of Paediatrics and Child Health, UK

DCH, Royal College of Paediatrics and Child Health, UK

FHEA, Fellow of the Higher Education Academy, UK

MBBS (Honours) University of Sydney, Australia

Master of Medical Science (Child Health, Diabetes and Endocrinology) University of Liverpool

PhD (Child Health) University of Liverpool

Master in Laws , University of Liverpool</xml> <

Grant details:

Winner of 2015 Diabetes Quality in Care (QiC) award
Finalist Commended 2017 Diabetes Team of the year Diabetes Quality in Care (QiC) award
Pride Awards 2015 Team of the Year Southport & Ormskirk NHS Trust
Highly Commended Diabetes Team of the Year 2015 BMJ awards
Finalist HSJ Clinical Leader of the year 2015
Finalist in the UK Asian Woman of Achievement Award
Newborn Appeal Grant 2011
Best Research Abstract Award 2010 BSPED UK
Newborn Appeal Grant 2007
MRC Fellowship 2006 Medical Research Council, UK
University Prize for Paediatrics,    University of Sydney, Australia

Number of Publications: 50

1.    Ng SM, Turner MA, Avula S. Ultrasound measurements of thyroid gland volume at 36 weeks corrected gestational age in extreme preterm infants born before 28 weeks gestation. European Thyroid Journal 2017.

2.    Apperley L, Ng SM. Socioeconomic Deprivation, Household Education and Employment are Associated With Increased Hospital Admissions and Poor Glycemic Control in Children With Type 1 Diabetes Mellitus. Review of Diabetic Studies 2017

3.    Ng SM. Digital Footprints: Steps towards transformation in paediatric diabetes. Journal of MHealth 2017, March ow.ly/g6Um30aYCZU

4.    Ng SM, Stepien K. Glucocorticoid replacement regimens in the treatment of 21-hydroxylase deficiency congenital adrenal hyperplasia (Protocol) published Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No CD012517. DOI: 10.1002/14651858.CD012517

5.    Ng SM, Edge J. Hyperglycaemic Hyperosmolar State (HHS) in children: A practical guide to management. Paediatrics and Child Health Journal 2017 http://dx.doi.org/10.1016/j.paed.2017.01.002

6.    Ng SM, Soni A, Didi M. Neonatal Pituitary-Thyroid Axis Dysregulation with Combined Thyroid Hormone and Thyrotropin Resistance in Infant with Trisomy 21 and Maternal Subclinical Hypothyroidism. J Neonatal Biol 2016 5:4 DOI: 10.4172/2167-0897.1000243

7.     Ng SM, Agwu JC, Dwan K. A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children. Arch Dis Child 2016 :1–7. doi:10.1136/archdischild-2015-308925

8.    Ng SM, Turner M. The Importance of Risk Stratification and Management of Newborn Babies of Women with a History of Graves’ disease. Int J Clin Endocrinol Metab 2016, 2(1): 001-004
9.    Soni A, Agwu JC, Kershaw M, Edge J, Wright N, Ng SM. Management of children with type 1 diabetes during illness: a national survey. Postgrad Med J 2015 doi:10.1136/postgradmedj-2015-133786

10.    Ng SM, Vizard M. The great enabler: how technology is helping to improve patient outcomes in paediatric diabetes. British Journal of Diabetes and Vascular Disease 2015;15:86-88

11.    Soni A, Ng SM. Type 1 and Type 2 diabetes in children and young people: updated NICE guidance. Practical Diabetes 2015;32:281-282

12.    Ng SM. Improving patient outcomes with technology and social media in paediatric diabetes. BMJ Quality Improvement Reports 2015; 4(1) DOI:10.1136/bmjquality.u209396.w3846 (1)

13.    Ng SM, Watson G, Turner MA, Newland P and Weindling AM. Do maternal factors influence neonatal thyroid status in the extreme premature infant? The Journal of Maternal-Fetal & Neonatal Medicine 2014:26:1-11.

14.    Agwu C, Ng SM, Edge DA, Wright. Care of children and young people with diabetes who require surgery. Diabetes Care for Children and Young People 2014:3:106-110

15.    Ng SM, Soni A. Intensive diabetes management and goal setting are key aspects of improving metabolic control in children and young people with Type 1 diabetes mellitus. World Journal of Diabetes 2014: 5(6): 877-881 DOI: http://dx.doi. org/10.4239/wjd.v5.i6.877

16.    Ng SM, Finnigan L, Connellan L, Caitriona Kerinan, Coward S. Improving paediatric diabetes care with the use of an integrated paediatric electronic diabetes information management system and routine uploading of blood glucose meters and insulin pumps in outpatient clinics. Archive of Disease in Childhood 2014; 99:1059 doi:10.1136/archdischild-2014-307021

17.    Ng SM, Mariguddi S, Coward S, Middleton H. Successful implementation of a paediatric community home nursing service as a model of service delivery in acute paediatric care. British Journal of Nursing 2014: 23 (4):209-212.

18.    Ng SM, Turner MA, Watson G, Victor S, Isherwood DM, Newland P, Didi M and Weindling AM. Is dopamine an iatrogenic disruptor of thyroid and cortisol function in the extremely premature infant? Advances in Endocrinology 2014; DOI:http://dx.doi.org/10.1155/2014/973184

19.    Soni A, Shaw EJ, Natarajan A, Ng SM. Children with Type 1 Diabetes mellitus developing concurrent autoimmune disease are not at risk of worsening metabolic control or growth impairment. Practical Diabetes 2014: 31(6):243-246

20.    Ng SM, Turner MA, Didi M, Parkes L, Tietze A, Atkinson J, Sluming V and Weindling AM. Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings from the TIPIT study. Pediatric Radiology 2014:44 (8):987-96

21.    Ng SM, Balmuri S. Review of insulin treatment in stress related hyperglycaemia in children without pre-existing diabetes. Acta Paediatrica 2013 doi:10.1111/apa.12442
22.    Ng SM, Turner MA, Victor S, M Didi, C Gamble, D Manning, R Gupta, P Settle. P Newland and Weindling AM. An explanatory randomised placebo-controlled trial of thyroxine supplementation in extreme preterm Infants < 28>
23.    Murphy A, Martin P, Jukka C, Menon A, Ng SM. Recurrent primary paediatric herpetic whitlow of the big toe. BMJ Case Reports 2013 doi:10.1136/bcr-2013-008598

24.    Murphy C and Ng SM. Institution of multiple daily insulin regimen compared with twice daily pre-mixed insulin regimen for children with Type 1 Diabetes Mellitus. American Journal of Clinical Medicine Research 2013  1 (1). doi: 10.12691/ajcmr-1-1-2

25.    Ng SM, Drury JA, Turner MA, M Didi, Victor S, Paul Newland, Weindling AM. A Novel Method of Collection of Saliva for Estimation of Steroid Levels in Extremely Premature Infants. Acta Paediatrica 2013:102 (4): 356-9

26.    Gangadharan A, Hanumanthaiah H, Ng SM.  The Use of Iodine as First Line Therapy in Graves' Disease Complicated with Neutropenia at First Presentation in a Paediatric Patient. British Journal of Medicine and Medical Research, 3(2): 324-328, 2013

27.    Hanumanthaiah H, Gangadharan A, Ng SM. Continuous insulin infusion therapy for acute stress hyperglycemia secondary to asthma exacerbation in a paediatric patient. Journal of Diabetes Research and Clinical Metabolism 2012: http://dx.doi.org/10.7243/2050-0866-1-19

28.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  Multivariate analysis of factors that affect neonatal screening thyrdois stimulating hormone. Journal of Pediatric Endocrinology and Metabolism 2011, 24: 727-732

29.    Hussain M, Cheri J, Khalid M, Matouk Z, Ng SM, Chanderasekaran S, Didi M, Blair J. Growth monitoring still has a place in selected populations of children. BMJ Case Reports 2011; doi:10.1136/bcr.01.2010.2640

30.    Ng SM, Weindling MA. The impact of networks on clinical trials in the United Kingdom . Trials 2009, 10:100

31.    Ng SM, Turner MA, Gamble C, M Didi, Victor S, Malamateniou C, Parkes L, Tietze A, Gregory L,Sluming V, Abernethy L and Weindling AM. TIPIT: A Randomised Controlled Trial of Thyroxine in Preterm Infants under 28 weeks Gestation: Magnetic Resonance Imaging and Magnetic Resonance Angiography Protocol. BMC Pediatrics 2008, 8:26

32.    Ng SM. Hypothyroxinemia of prematurity: cause, diagnosis and management. Expert Review of Endocrinology & Metabolism 2008, 3: 453-462

33.    Ng SM, Dhullipala A, Weindling AM. High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism. Cochrane Database of Systemic Reviews 2008, Issue 1

34.    Ng SM, Turner MA, Gamble, Didi M, Victor S, Weindling AM. TIPIT: A Randomised controlled trial of thyroxine in preterm infants born under 28 weeks gestation. Trials 2008, 9: 17

35.    Ng SM, Wong SC, Isherwood DM, Didi M. Biochemical severity of thyroid ectopia in congenital hypothyroidism demonstrates sexual dimorphism. European Journal of Endocrinology 2007, 156: 49-53

36.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  There is a delay in screening premature infants for congenital hypoithyroidism. Archives of Disease in Childhood Fetal Neonatal Ed 2006, 91: F465-466

37.    Ng SM, May JE, Emmerson AJB. Continuous insulin infusion in hyperglycemic ELBW infants: An evaluation of treatment response. Biology of the Neonate 2005, 4: 269-272

38.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. The gonadotrophins response to GnRH test is not a predictor of neurological lesion in girls with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism 2005, 18: 849-852

39.    Ng SM, Wong SC, Isherwood DM, Smith CS, Didi M. Multivariate analysis on factors affecting suppression of thyroid stimulating hormone in treated congenital hypothyroidism. Hormone Research 2004, 20: 245-251

40.    Wong SC, Ng SM, Didi M. Children with congenital hypothyroidism are at risk of adult obesity due to early adiposity rebound. Clinical Endocrinology 2004, 61: 441-6

41.    Ng SM, Wong SC, Didi M. Head circumference and linear growth during the first 3 years in treated congenital hypothyroidism in relation to aetiology and initial biochemical severity. Clinical Endocrinology 2004, 61: 155-9

42.    Chalameau M, Hadjiaathanasiou C, Ng SM, Cassio A, Mul D, Cisternino M, Partsch CJ, Theodoris C, Didi M, Cacciari E, Oostdijk W, Borghesi A, Sippell WG, Breart G, Brauner R. How to select girls with precocious puberty for brain imaging? An evidence based approach: EUROPUB study. A multicentre trial. Journal of Pediatrics 2003, 143: 445-450

43.    Ng SM, Jones AP. Drug therapies for reducing gastric acidity in people with cystic fibrosis. Cochrane Collaboration, Cochrane Library 2003, Issue 2

44.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. Cranial MRI scans are indicated in all girls with central precocious puberty. Archives of Disease in Childhood 2003, 88:  414-418

45.    Cody D, Ng SM, Didi M and Smith CS. The differing outcomes of hyperthyrotropinemia. Journal of Paediatric Endocrinology and Metabolism 2003, 16: 375-378

46.    Ng SM, Khurana R, Hughes U, Manning D. Is prolonged use of computer games a risk factor for deep venous thrombosis in children? Clinical Medicine 2003, 6: 593-594

47.    Ng SM, Toh EM and Sherrington CA. Clinical predictors of abnormal computed tomography scans in paediatric head injury. Journal of Paediatrics and Child Health 2002, 38: 388-392

48.    Ng SM, Ariffin WA, Lin HP, Chan LL and Chin YM. Clinical features and treatment outcome of children with myeloid antigen coexpression in B-lineage acute lymphoblastic leukemia. Journal of Tropical Paediatrics 2000, 46: 73-78

49.    Ng SM, Lin HP, Ariffin WA, Lam SK and Chan LL. Age, sex, hemoglobin and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol. Journal of Tropical Paediatrics 2000, 46:  338-343

50.    Ng SM, Ariffin WA, Lin HP and Chan LL. Presenting features and treatment outcome of 78 Malaysian children with neuroblastoma. Southeast Asian Journal of Tropical Medicine and Public Health 1999, 30: 149-153



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Editorial Board

Efstratios Moralidis
Department of Nuclear Medicine
Aristotle University Medical School
Greece
emoral@med.auth.gr
IJCEM

Research Interest: An ongoing study on the assessment of renal function in the course of diabetes mellitus

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Wellerson Rodrigo Scarano
Associate Professor
Department of Human Embriology
Sao Paulo State University
Brazil
wrscarano@yahoo.com
IJCEM

Research Interest: Environmental toxins and prostate development,  Endocrine disruptors and urogenital development, Carcinogenesis rodent models for prostate cancer, Chemoprevention in rodent models of prostate carcinogenesis and human cancer cells (in vitro) – AKT pathway evaluation, Reproductive Endocrinology and Infertility, Effects of endocrine disruptors in human Sertoli cells (in vitro) with focus in adhesion molecules, AR pathway and DNA methylation

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Clemens Furnsinn
Department of Medicine
Medical University of Vienna
Austria
clemens.fuernsinn@meduniwien.ac.at
IJCEM

Research Interest: Glucose metabolism; insulin sensitivity; diabetes mellitus; obesity; animal models; antidiabetic drugs; preclinical pharmacology

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Nadia Alfaidy
Research Institute of Technology
Science for Life Sciences
France
nadia.alfaidy-benharouga@cea.fr
IJCEM

Research Interest: Research has been focused on the understanding of the mechanisms of the development of Peeclampsia, the most common cause of retarded fetal development.

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Sabrina Grassiolli
Professor
Department of Biological Sciences
Ponta Grossa State University
Brazil
sgrassiolli@bol.com.br
IJCEM

Research Interest: General Physiology, Endocrine Physiology, Neuroendocrine Regulation of Body Weight, Epidemiology of Obesity and Diabetes, Endocrinology, Exercise Effect Evaluation

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Beatriz Puisac Uriol
Professor
Department of Physiology
University of Zaragoza
Spain
puisac@unizar.es
IJCEM

Research Interest: Genetic disorder, splicing mutations, Cornelia de Lange Syndrome, HMG-CoA lyase deficiency, HMG-CoA synthase deficiency

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Janos Szolcsanyi
Department of Pharmacology
University of Pecs
Hungary
janos.szolcsanyi@aok.pte.hu
IJCEM

Research Interest: Physiology and pharmacology of nociceptors by means of capsaicin to open new horizons for development nociceptor targeted analgesic/anti-inflammatory agents and to reveal sensory-efferent dual functions of capsaicin-sensitive nociceptors

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Juan de Dios Beas Jimenez
Andalusian Center of Sports Medicine
Spain
puisac@unizar.es
IJCEM

Research Interest: Sports Injuries.,Sports and Health.,Sarcopenia.,Sports nutrition

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Beata Ewa Pyrzak
Assistant Professor
Department of Paediatric and Endocrinology
Clinic of the Medical University
Poland
bpyrzak@wum.edu.pl
IJCEM

Research Interest: Endocrinology, diabetes, obesity, genetics, children

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Choi Marcelo Roberto
Professor
Department of Human Anatomy and Histology
University of Buenos Aires
Argentina
marcelinkchoi@yahoo.com.ar
IJCEM

Research Interest: Angiotensin II effects on renal dopamine metabolism using in vitro models and different techniques like pharmacological approaches, kinetic studies, enzymatic activities and radiolabel markers. For my postdoctoral work, I expanded my research area and studied the relationship between atrial natriuretic peptide and renal dopamine system and its impact on sodium handling. For this purpose we employed an in vivo model to evaluate this interaction on urinary parameters and used molecular techniques to demonstrate the involvement of different tubular transports

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Domenico Rubello
Professor
Department of Nuclear Medicine
University of Padua
Italy
domenico.rubello@libero.it
IJCEM

Research Interest: Molecular Imaging in Oncology with SPECT/CT, PET/CT and PET/MR.

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Sze May NG
Director
Department of Paediatrics
University of Liverpool
UK
may.ng@nhs.net
IJCEM

Research Interest: Type 1 diabetes, thyroid disorders and puberty.

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Paola Di Carlo
Department of Infectious Disease
University of Palermo Palermo
Italy
paola.dicarlo@unipa.it
IJCEM

Research Interest: Tuberculosis, hospital infections, HIV, pediatric infectious Disease

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Zhenyi Su
Department of Biochemistry and Molecular Biology
Southeast University
China
suzhenyi999@163.com
IJCEM

Research Interest: The novel functions of calcineurin B subunit (CnB) in the activation of innate immunity and in cancer treatment. We have identified the integrin αM as a new receptor of CnB on macrophage and revealed how this receptor mediates CnB-triggered anti-tumor activity. We also showed that CnB protein can synergize with inteferon-γ to skew tumor-associated macrophages (TAMs) to an anti-tumor phenotype (M1 phenotype) and to enhance inteferon-γ- mediated tumoricidal activity. So far, I mainly focus on the molecular mechanisms of necroptosis (a new form of programmed cell death). We are trying to reveal new modulators in the regulation of necroptotic pathway, and to reveal the roles and mechanisms of necroptosis in tumorgenisis and metastasis

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Theun de Groot
Researcher
The Jackson Laboratory
USA
theun.degroot@jax.org
IJCEM

Research Interest: Primary: Kidney (patho-)physiology Secondary: Diabetes mellitus, oxidative stress, ion transport

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