ISSN: 2640-7582 Open Access International Journal of Clinical Endocrinology and Metabolism Clinical Group

International Journal of Clinical Endocrinology and Metabolism

    Reviewer Board

    Li Wang
    Associate Professor
    Medical College of Wisconsin
    USA
    IJCEM
    Research Interest: Immune-checkpoint proteins suppress tumor-specific immune responses and hamper the efficacy of cancer vaccine. My research in the past 7 years has been focused on understanding how immune-checkpoint proteins regulate anti-tumor immunity. My earlier work has identified a novel function of PD-1, an established immune-checkpoint protein in regulating the differentiation of tumor-induced adaptive Foxp3+ CD4+ regulatory T cells (PNAS, 2008). My recent work has discovered VISTA, a novel immune-checkpoint protein that critically regulates tumor-specific immunity (JEM, 2011). My ongoing work focuses on understanding VISTA-mediated immune regulation in, and designing novel combinatorial strategies that targets VISTA and additional immune-checkpoint proteins such as CTLA-4 and PD-1 for cancer immunotherapy
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