International Journal of Immunotherapy and Cancer Research is a multi-disciplinary peer-reviewed, open access journal. Journal brings together all the varied aspects of research that will ultimately lead to the prevention of cancer. With the goal of advancing technology and improving healthRead more
Research Interest: Study of the mechanism of action, toxicity and efficacy of anticancer agents, as well as in the field of clinical pharmacology of chemotherapeutic drugs, including modeling of pharmacogenetic studies
Research Interest: Molecular Biology/Cancer Biology
Research Interest: Research areas of human physiology and pathophysiology. His research focuses on the clinical evaluation of new biomarkers and molecular mediators in several pathophysiological disease states, such as diabetes, atherosclerosis and cancer. His research interest also includes the development of quantitative structure-activity relationships (QSARs) and quantitative structure-property relationships (QSPRs) in the area of toxicology and pharmacology. Furthermore, his research interest lies in the assessment of physicochemical properties, such as lipophilicity, solubility and ionization of drugs, natural bioactive compounds and toxic chemicals in relation with their potential biological activity and toxicity endpoints, as well as their Absorption/Distribution/Metabolism/Excretion (ADME) parameters and their pharmacokinetic and toxicokinetic profiles
Research Interest: Cancer Genetics, Apoptosis, Oncogenes, Tumor
Suppressor Genes, Mechanisms of Anti-Cancer Drug Resistance.
Research Interest: Cellular and Ultrastructural Biology, Tumor Morphometry and Enzymology, Fractals in Biology and Medicine, Apoptosis , Human Leukemia, Lymphocyte ultrastructure and metabolism.
Research Interest: Anti-Cancer, Apoptosis, Blebbing, Caspases, Cell Cycle, Cell Signaling, Cancer,
DNA Fragmentation, Drug Discovery, Flow Cytometer, Intrinsic and extrinsic
apoptosis pathway, Laser Confocal Microscope, Mitochondrial Depolarization and Necrosis.
Research Interest: Melanoma, kidney cancer , immunotherapy with ipilimumab, nivolumab, interleukin-2 and other agents.
• modelling, optimisation and control of biotechnological processes;
• drug design, molecular modelling, virtual ligand screening;
• metaheuristic algorithms;
• intuitionistic fuzzy logic;
• generalised nets;
• intercriteria analysis in decision making systems
Research Interest: Immunophenotyping, Immunocytochemistry, Multilineag differentiation, RNA isolation, RT- PCR, Cancer cell line, Immunocytochemistry, Real-Time PCR, Western blot, Transport mechanism by liquid santillation Counter, Induction of leukemia in experimental animal, Biochemical enzymatic analysis, TEM analysis, Histopathology, RT-PCR, apoptosis analysis, Western blot, MTT assay, Measurement of intracellular ROS, Analysis of mitochondrial membrane potential, Intracellular calcium levels, Quantiﬁcation of endogenous GSH, DNA fragmentation, Column Chromatography, Antibiotic sensitivity assay, Extract preparation, Antibiotic sensitivity assay
Research Interest: To study the metabolic adaptation for survival occurring in the cancer cells
Research Interest: signaling pathways, molecular studies and biosensor development for detection of cancer with the collaboration of nanotechnology experts.
Research Interest: These cancers express unique tumor-specific or
-associated antigens to which my lab directs T cell immune responses via DNA,
RNA, protein or peptide based vaccines.
Vaccine components are delivered in their native form, by dendritic
cells, by recombinant Adeno Associated Virus.
This clinically translational research is backed up by pre-clinical and
basic research in both normal and transgenic animal models and in laboratory
studies on patient material. Results from the pre-clinical studies have led to a variety of clinical trials
for which I am the immunological coordinator.
Research Interest: Immunology, Cancer, ImmunoTherapy, Autoimmunity
Research Interest: Unctional, heterogeneit of stromal cells lymphoid organs during health and
disease particularly cancer.
Research Interest: Tumour Microenvironment and Translational Cancer Medicine
Combination of cancer target therapy and immunotherapy
Tumour associated macrophages
Notch signalling in cancer biology
Tumour resistance to target therapy and immunotherapy
Hypoxia and angiogenesis pathways in cancer biology
MicroRNAs in cancer target therapy and immunotherapy
Experimental mouse tumour models
Published On: October 06, 2016 | Pages: 011 - 013View Article DOI: 10.17352/2455-8591.000009
Published On: June 17, 2016 | Pages: 003 - 010View Article DOI: 10.17352/2455-8591.000008
Published On: January 23, 2016 | Pages: 001 - 002View Article DOI: 10.17352/2455-8591.000007
Published On: October 28, 2015 | Pages: 021 - 028View Article DOI: 10.17352/2455-8591.000006
Published On: October 13, 2015 | Pages: 018 - 022View Article DOI: 10.17352/2455-8591.000005
Published On: September 03, 2015 | Pages: 013 - 017View Article DOI: 10.17352/2455-8591.000004
Published On: August 20, 2015 | Pages: 008 - 012View Article DOI: 10.17352/2455-8591.000003
Published On: August 14, 2015 | Pages: 004 - 007View Article DOI: 10.17352/2455-8591.000002
Published On: August 05, 2015 | Pages: 001 - 003View Article DOI: 10.17352/2455-8591.000001