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International Journal of Immunotherapy and Cancer Research  Open Access

    Executive Editor(s)

    Eugenia Yiannakopoulou
    Doctor
    Medical Laboratories Faculty of Health and Caring Professions
    Highest Technological Educational Institution, Athens University of Applied Sciences
    Greece
    nyiannak@teiath.gr
    IJICR

    EugeniaYiannakopoulou works as an Academic Teacher in the Department of Medical Laboratories of the Faculty of Health and Caring Professions, Technological Educational Institute of Athens (Athens University of Applied Sciences), Greece.  Since 2015 she works as a Faculty Staff of the Master in Science  Biomedical Methods and Technology in Diagnosis organized by the Department of Medical Laboratories Highest Technological Educational Institute of Athens.  She is Director of her own private medical practice where she works as a consultant surgeon with special interest in Endocrine Surgery and Breast Surgery.

    Eugenia Yiannakopoulou graduated from the Medical School of National and Kapodistrian University of Athens. Postgraduate studies: MSc Minimally Invasive Surgery; MSc Medical Biology; MSc Biostatistics; PhD Pharmacology; University Diploma in Breast Diseases Medical School University of Strasbourg, France; University Diploma of Laparoscopic Surgery Medical School University of Strasbourg, France. University Diploma of Endocrine Surgery Medical School  University Pierre et Marrie Currie Paris, University Diploma in Targeted Biotherapeis of Inflammatory and Autoimmune Diseases, Medical School University of Montpellier, University Diploma in Inflammatory Bowel Diseases Medical School University Pierre et Marie Currie Paris.   She has completed postdoctoral research in Pharmacology. Eugenia Yiannakopoulou is Hellenic National Board certified in Surgery. She speaks English, German, Italian, French, Russian, Spanish, Portugues, Dutch.

    Eugenia Yiannakopoulou is member of the European Association of Endoscopic Surgery, of the European Society of Endocrine Surgeons, of the British Pharmacological Society, of the European Association of Clinical Pharmacology and Therapeutics, of the European Network for the study of Adrenal Tumors.  Eugenia Yiannakopoulou is member of the Research Committee of the European Association of Endoscopic Surgery.

    She has authored 57 research papers published in international journals and 6 book chapters and has presented 60 papers at national and international conferences. She is a Reviewer of peer-reviewed journals including Surgical Endoscopy, British Journal of Surgery, European Journal of Pharmacology, Journal of Clinical Pharmacology, Pharmacotherapy, Annals of Pharmacotherapy, European Journal of Preventive Cardiology, Molecular Nutrition and Food Research. She is a member of the Editorial Board of a number of journals.

    URL: https://www.researchgate.net/profile/Eugenia_Yiannakopoulou

    Grant details:
    2013 Prize for Best Oral Presentation 2nd Panhellenic and International Congress “From Basic Science to Clinical Practice for Urogenital Tract, Stomach, Pancreas, Brain Tumors and Soft Tissue Sarcomas Athens 12-13 April 2013
    2012 Travel Grant 20th EAES Congress Brussels
    2012 Grant of the Hellenic Surgical Society for postgraduate training in Robotic Surgery
    2011 Travel Grant 19th EAES Congress Torino Italy
    2011 Prize for Best Oral Presentation “2nd Balkan Venous Forum and 3rd Panhellenic Congress of Phlebology Athens 2011
    2010 Travel Grant 18th EAES Congress Geneva Switzerland
    2010 Young Investigator Award European Congress of Lymphology Athens Greece
    2008 Scholarship of Medical School University of Athens for studies in Msc of Minimally Invasive Surgery
    2005-2007 Scholarship of the National Scholarship Foundation for Postdoctoral Research in Laboratory of Pharmacology Medical School University of Athens with subject “Role of salicylates in preconditioning in oxidative stress”
    2003-2004 Scholarship of Academy of Athens for postgraduate studies in Epidemiology-Public Health, after successful participation in exams
    1989-1994 Scholarship of the University of Athens after successful participation n exams
    1992  Erasmus Scholarship •    June-August /1992  Three month fellowship in Obstetrics-Gynaecology in Royal Free Hospital of London
    1991 Scholarship of the Hellenic Medical Student Association One month fellowship in Neurosurgery University Hospital of Odessa Ukrania.

    List of Publications: 63

    1.    Francis N, Kazaryan AM, Pietrabissa A, Goitein D, Yiannakopoulou E, Agresta F, Khatkov I, Schulze S, Arulampalam T, Tomulescu V, Kim YW, Targarona EM, Zaninotto G A research agenda for the European Association for Endoscopic Surgeons (EAES). Surg Endosc. 2017 May;31(5):2042-2049
    2.    Eugenia Yiannakopoulou The role of minimally invasive surgery in neuroendocrine pancreatic tumors Minerva Chir. 2017 Mar 27. doi: 10.23736/S0026-4733.17.07350-3
    3.    Eugenia Yiannakopoulou A Case Approach to Perioperative Drug-Drug Interactions. Anesth Analg. 2017 Mar 24. doi: 10.1213/ANE.0000000000001981.
    4.    Eugenia Yiannakopoulou Botulinum toxin and safety issues in cerebral palsy. Dev Med Child Neurol. 2017 Mar;59(3):245.
    5.    Eugenia Yiannakopoulou  Robotic assisted adrenalectomy: surgical techniques, feasibility, indications, oncological outcome and safety: Systematic Review Int J Surg. 2016 Apr;28:169-72
    6.    Eugenia Yiannakopoulou, Carole Mathelin ONCOPLASTIC BREAST CONSERVING SURGERY AND ONCOLOGICAL OUTCOME: SYSTEMATIC REVIEW Eur J Surg Oncol. 2016 May;42(5):625-30
    7.     Eugenia Yiannakopoulou Sclerotherapy of varicose veins and safety issues Pharmacology 2016 Apr 23;98(1-2):62-69
    8.    Eugenia Yiannakopoulou Minimally invasive pancreatic surgery Minerva Chir. 2015 Dec;70(6):437-50
    9.    Eugenia Ch Yiannakopoulou Pharmacogenomics and Opioid Analgesics: Clinical Implications Int J Genomics. 2015;2015:368979
    10.    Eugenia Ch Yiannakopoulou Targeting DNA Methylation with Green Tea Catechins Pharmacology. 2015 Mar 13;95(3-4):111-116
    11.    Eugenia Ch Yiannakopoulou Serious and long-term adverse events associated with the therapeutic and cosmetic use of botulinum toxin Pharmacology. 2015;95(1-2):65-9. doi: 10.1159/000370245. Epub 2015 Jan 21
    12.    Eugenia Ch Yiannakopoulou Pharmacovigilance for novel oral anticoagulants: why is it so crucial? J Pharmacovigilance 2015 in process
    13.    Eugenia Ch Yiannakopoulou Interaction of green tea catechins with breast cancer endocrine treatment: a systematic review Pharmacology. 2014;94(5-6):245-8. doi: 10.1159/000369170. Epub 2014 Nov 28
    14.    Eugenia Ch Yiannakopoulou Interaction of Salicylates and the Other Nonsteroidal Anti-Inflammatory Agents With Breast Cancer Endocrine Treatment: Systematic Review Am J Clin Oncol. 2014 Dec 10. [Epub ahead of print]
    15.    Yiannakopoulou E, Nikiteas N, Perrea D, Tsigris C Virtual reality simulators and training in laparoscopic surgery Int J Surg.  2015 Jan;13:60-4. doi: 10.1016/j.ijsu.2014.11.014. Epub 2014 Nov 18
    16.    Eugenia Ch Yiannakopoulou Aspirin and NSAIDs for breast cancer chemoprevention Eur J Cancer Prev. 2014 Nov 6. [Epub ahead of print]
    17.    Eugenia Ch Yiannakopoulou Targeting epigenetic mechanisms and microRNAs by aspirin and other non steroidal anti-inflammatory agents--implications for cancer treatment and chemoprevention Cell Oncol (Dordr). 2014 Jun;37(3):167-78.
    18.    Eugenia Ch Yiannakopoulou Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications. Cell Oncol (Dordr). 2014 Feb;37(1):1-8. doi: 10.1007/s13402-013-0158-0. Epub 2013 Dec 4
    19.    Eugenia Ch Yiannakopoulou Green tea catechins: Proposed mechanisms of action in breast cancer focusing on the interplay between survival and apoptosis Anticancer Agents Med Chem. 2014 Feb;14(2):290-5
    20.    Eugenia Ch Yiannakopoulou Pharmacovigilance and NSAIDs J Pharamcovigilance 2014  http://dx.doi.org/10.4172/2329-6887.1000e116
    21.    Eugenia Ch Υiannakopoulou Targeting oxidative stress response by green tea polyphenols: clinical implications Free Radic Res. 2013 Sep;47(9):667-71
    22.    Eugenia Ch Υiannakopoulou Effect of green tea catechins on breast carcinogenesis: a systematic review of in-vitro and in-vivo experimental studies Eur J Cancer Prev 2013 Aug 9
    23.    Eugenia Ch Υiannakopoulou , Nikolaos  Νikiteas , Despina Perrea ,  Christos Tsigris Effect of laparoscopic surgery on oxidative stress response: Systematic Review Surg Laparosc Endosc Percutan Tech. 2013 ;23(2):101-8
    24.    Υiannakopoulou Eugenia, Νikiteas Nikolaos, Perrea Despina, Tsigris Christos. Minimally invasive surgery and stress response Systematic review of animal data Surg Laparosc Endosc  Percutan Tech 2013; 3:101-8
    25.    Yiannakopoulou E Pharmacogenomics of acetylsalicylic acid and other nonsteroidal anti-inflammatory agents: clinical implications Eur J Clin Pharmacol In Press
    26.    Eugenia Ch Yiannakopoulou Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications  Pharmacogenomics J 2013 13:105-9
    27.    Eugenia Yiannakopoulou Does Pharmacodynamic Interaction of Non Enzymatic Antioxidants Modify Response to Anti-Oxidant Therapy in the Process of Atherosclerosis? J Cardiovasc Pharmacol 2012;17:366-72
    28.    Eugenia Yiannakopoulou Modulation of lymphangiogenesis: a new target for aspirin and other non steroidal anti-inflammatory agents? Systematic Review Clin Pharmacol. 2012;52:1749-54
    29.    Eugenia Ch Υiannakopoulou, Nikolaos  Νikiteas, Despina Perrea,  Christos Tsigris Pharmacological preconditioning of oxidative stress response: Systematic Review Surg Laparosc Endosc  Percutan Tech 2012 22;200-204
    30.    Eugenia Yiannakopoulou Pharmacogenomics of breast cancer targeted therapy: focus on recent patents Recent Pat DNA Gene Seq 2012;6:33-46
    31.    Eugenia Yiannakopoulou Recent patents on antibacterial, antifungal and antiviral properties of tea Recent Pat Anti-infect Drug Discov 2012;7:60-65
    32.    Eugenia Yiannakopoulou Botulinum toxin and anal fissure: Efficacy and safety-Systematic Review Int J  Colorectal Dis 2012;1:1-9
    33.    J Griniatsos, E. Yiannakopoulou, H. Gakiopoulou, A.Alexandrou, N. Dimitriou, I. Karavokyros, E. Felekouras Clinical implications of the histologically and immunohistochemically detected solitary lymph nodes metastases in gastric cancer Scand J Surg 2011;100:174-180
    34.    Yiannakopoulou E. Hemoptysis under diclofenac and antiplatelet doses of aspirin. Pharmacology 2011;87:1-4
    35.    Yiannakopoulou E Effect of aspirin in hemostasis: synergism or antagonism with non steroidal anti-inflammatory agents. IIOAB Journal 2010 1;29-32
    36.    Griniatsos J, Alexandrou A, Yiannakopoulou E A SIMPLE TECHNIQUE FOR VACUUM DRAINAGE OF THE PERITONEAL CAVITY IN THE MANAGEMENT OF ANASTOMOTIC LEAKS Accepted for publication in Journal of Buon
    37.    Yiannakopoulou E 7th Biennial Congress of the Mediterranean Society of Coloproctology (MSCP), Thessaloniki Greece, April, 22-24, 2010 Tech Coloproctol 2010;14:291-292
    38.    E. Yiannakopoulou and E. Tiligada Preconditioning effect of salicylates against oxidative stress in yeast. Journal of Applied Microbiology 2009;106:903-908
    39.    Ε.Yiannakopoulou Methodological issues regarding safety evaluation in randomized controlled trials of the effectiveness of antibiotic prophylaxis for the prevention of postoperative wound infection.  J Antimicrob Chemother  2009 ;63:843-845
    40.    Griniatsos J, Yiannakopoulou E, Tsehpenakis A, Tsigris Ch, Diamantis Th.  Α Hybride technique for recurrent incisional hernia repair. Surg Laparosc Endosc Percutan Tec 2009;19:e177-e180
    41.    Griniatsos J, Gakiopoulou H, Yiannakopoulou E, Dimitriou N, Douridas G, Nonni A, Liakakos Th, Felekouras E.  Routine modified D2 lymphadenectomy performance in pT1-T2N0 gastric cancer tumors World J Gastroenterol 2009;28:5568-5572 
    42.    Yiannakopoulou Eugenia Oxidative stress-antioxidant mechanisms-clinical implications Archives of Greek Medicine 2009;26:23-35
    43.    E. Yiannakopoulou Gynaecomastia and statins Epitheor Pharmacol Pharmacokinet 2009;27:19-22
    44.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Adherence to guidelines for antibiotic prophylaxis in general surgery: a critical appraisal. Journal of Antimicrobial Chemotherapy 2008;61:214-218
    45.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Surgical Site Infections Surveillance in general surgery: a critical issue Journal of Chemotherapy 2008;20:312-318 
    46.    E.Ch Yiannakopoulou Cephalosporin induced anaemia in surgical patients Review of Clinical Pharmacology and Pharmacokinetics International Edition 2008; 22:363-365
    47.    Ε.Ch Yiannakopoulou and E.Tiligada Pharmacological preconditioning in the oxidative stress response of eukaryotic cells: In process method validation Review of Clinical Pharmacology and Pharmacokinetics Greek Edition* 2007;25:30-32
    48.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Antibiotic prophylaxis and adverse reactions of antibiotics in general surgery Review of Clinical Pharmacology and Pharmacokinetics International Edition 2006;20:338-340
    49.    Ε.Ch Yiannakopoulou and E.Tiligada Acetaminophen modulates the oxidative stress response in eucaryotic cells Review of Clinical Pharmacology and Pharmacokinetics International Edition 2006;20:125-127
    50.    Eugenia Ch.Yiannakopoulou, John S.Papadopulos, Dennis V. Cokkinos, Theodoros D. Mountokalakis Adherence to antihypertensive treatment: a critical factor for blood pressure control Eur J Cardiovasc Prev Rehabil 2005;12:243-249
    51.    E.Ch Yiannakopoulou, C.Damianou, C.Bamia, J.S.Papadopoulos Adequacy of safety data reporting in randomized clinical trials comparing coxibs with non-selective NSAIDs. Epitheor. Klin. Farmakol. Farmacokinet.* 2005;23:42-43
    52.     Ε.Ch.Yiannakopoulou, A.Delitheos, E.Tiligada  Dose-dependent effect of non-steroidal anti-inflammatory agents on the cellular stress response Epitheor. Klin. Farmacol. Farmakokinet.  2005;23:39-41
    53.    Τourmousoglou CE, Kalapothaki V, Yiannakopoulou E, Bramis J, Papadopulos JS Evaluating the adequacy of the prophylactic usage of antimicrobial drugs in surgical patients Review of Clinical Pharmacology and Pharmacokinetics International Edition* 2002;16: 27
    54.    E.Ch.Yiannakopoulou, J.S.Papadopulos, D.Cokkinos, T.Mountokalakis Side effects of antihypertensive medicines and how they influence the quality of treatment Review of Clinical Pharmacology and Pharmacokinetics, International Edition* 2002;16:109-110. and More......




    More Info.

    Editorial Board

    Eugenia Yiannakopoulou
    Scientific Associate
    Department of Biomedical Sciences
    University of West Attica
    Greece
    nyiannak@uniwa.gr
    IJICR

    Eugenia Yiannakopoulou: Surgeon; Endocrine Surgeon; Breast Surgeon; Pharmacologist. Current position:  Faculty in the Department of Biomedical Scineces, Faculty of Health and Caring Professions, ,University of West Attica, Athens,  Greece;  Director of her own private medical practice.  Titles: Ptychio of medicine; MSc Minimally Invasive Surgery; MSc Medical Biology; MSc Biostatistics; PhD Pharmacology; University Diploma in Breast Diseases University of Strasbourg, France; University Diploma of Laparoscopic Surgery University of Strasbourg, France. University Diploma of Endocrine Surgery University Pierre et Marrie Currie Paris, University Diploma in Targeted Biotherapeis of Inflammatory and Autoimmune Diseases, University of Montpellier, University Diploma in Inflammatory Bowel Diseases Medical School University Pierre et Marie Currie Paris.   Postdoctoral research in Pharmacology. She speaks English, German, Italian, French, Russian, Spanish, Portugues, Dutch. Member of the Research Committee of EAES. Research and Editorial Activity: Author of 60 publications, 641 citations, reviewer of international journals, Grant Reviewer, Congress Abstract Reviewer, Executive Editor of International Journal of Immunotherapy and Cancer Research, member of Editorial boards of International Journals.

    Research Interest: Minimally invasive surgery, endocrine surgery, breast surgery, surgical stress, surgical pharmacology, laparoscopic surgery, robotic surgery, surgical anatomy.

    List of Publication:

    [1] Yiannakopoulou E Systematic review of the effect of oxidative stress in minimally invasive surgery in comparison with conventional surgery. Msc Thesis for the Msc “Minimally invasive surgery, robotic surgery and telesurgery” Athens 2009

    [2] Yiannakopoulou E Investigation of the role of salicylates in preconditioning Final Report for Postdoctoral Research (IKY Scholarship 15109/07.10.2005) Athens 2007

    [3] Yiannakopoulou E Quality of diagnosis and treatment of arterial hypertension in Greece PhD Thesis Medical School University of Athens, Athens 2003 (3 Citations)

    [4] Yiannakopoulou E Meta-analysis of Randomized Clinical  Trials for the evaluation of safety of coxibs Msc Thesis for the Msc Biostatistics Medical School and Department of Mathematics Univesity of Athens, Athens 2004

    [5] Yiannakopoulou E Cellular mechanisms of adaptation in oxidative stress and in heat shock in Saccharomyces cerevisiae: the effect of antioxidants Msc Thesis for the Msc Medical Biology Medical School and Department of Biology University of Athens.

    BOOK CHAPTERS:

    1. Eugenia Ch Yiannakopoulou "BREAST CANCER PHARMACOGENOMICS: CLINICAL IMPLICATIONS FOR PERSONALIZED MEDICINE" for “Omics Aproaches for Breast Cancer” Editor Barth D published by Springer

    2. Eugenia Ch Yiannakopoulou " BREAST CANCER THERAPY- CLASSICAL THERAPY, DRUG TARGETS, AND TARGETED THERAPY" for “Omics Aproaches for Breast Cancer” Editor Barth D published by Springer

    3. Eugenia Ch Yiannakopoulou , Emmanuel O SALAWU,  Debmalya Barh. In silico models of disease In Animal Biotechnology: Models in discovery and Translation: A Verma and A Singh,  Edition Elsevier 1st Edition

    4. Eugenia Yiannakopoulou “Pharmacogenomics” in OMICS:Advances and applications Barth D, Raja R, Zambare V ( (IN press) Publisher Taylor Francis

    5.P.O. Michael, E. Yiannakopoulou, “Trauma of heart and pericardium” in “Trauma of Thorax” P. Michael Litsas Edition Athens 2002, pp 236-297 (in Greek).

    6. Τh.Diamantis, A.Kyritsis, D.Koronarchis, A.Kyriakopoulos, M.Kastanakis, E.Yiannakopoulou. “Laparoscopic treatment for gastroesophageal reflux disease. Five year experience”  in “Laparoscopic and other invasive techniques in the beginning of 21st century” 2000  Ch Tsigris, Th. Diamantis Litsas Edition Athens (in Greek)

    Book Translations in Greek: Three English Medical Books of Pharmacology and Physiology and three German Medical Books of Clinical  Pharmacology and Therapeutics.

    FULL PUBLICATIONS IN INTERNATIONAL PEER REVIEWED JOURNALS

    1.     Yiannakopoulou E. Minimally Invasive Parathyroidectomy in the Treatment of Patients with MEN I. J Surg Tech Proced. 2018; 2(2): 1019

    2.    Yiannakopoulou E.  Interplay  between  asthma  and  gastroesophageal  reflux  disease:  A  controversial  issue. Arch Asthma Allergy  Immunol. 2018; 2: 006-007. https://doi.org/10.29328/journal.aaai.1001011

    3.    Yiannakopoulou E Immunomodulatory effect of physical exercise: from immunosuppression to immune protection Virology and Immunology Journal 2018

    4.    Francis N, Kazaryan AM, Pietrabissa A, Goitein D, Yiannakopoulou E, Agresta F, Khatkov I, Schulze S, Arulampalam T, Tomulescu V, Kim YW, Targarona EM, Zaninotto G A research agenda for the European Association for Endoscopic Surgeons (EAES). Surg Endosc. 2017 May;31(5):2042-2049

    5.    Eugenia Yiannakopoulou The role of minimally invasive surgery in neuroendocrine pancreatic tumors Minerva Chir. 2017 Mar 27. doi: 10.23736/S0026-4733.17.07350-3

    6.    Eugenia Yiannakopoulou A Case Approach to Perioperative Drug-Drug Interactions. Anesth Analg. 2017 Mar 24. doi: 10.1213/ANE.0000000000001981.

    7.    Eugenia Yiannakopoulou Botulinum toxin and safety issues in cerebral palsy. Dev Med Child Neurol. 2017 Mar;59(3):245.

    8.    Eugenia Yiannakopoulou  Robotic assisted adrenalectomy: surgical techniques, feasibility, indications, oncological outcome and safety: Systematic Review Int J Surg. 2016 Apr;28:169-72

    9.    Eugenia Yiannakopoulou, Carole Mathelin ONCOPLASTIC BREAST CONSERVING SURGERY AND ONCOLOGICAL OUTCOME: SYSTEMATIC REVIEW Eur J Surg Oncol. 2016 May;42(5):625-30

    10.     Eugenia Yiannakopoulou Sclerotherapy of varicose veins and safety issues Pharmacology 2016 Apr 23;98(1-2):62-69

    11.    Eugenia Yiannakopoulou Minimally invasive pancreatic surgery Minerva Chir. 2015 Dec;70(6):437-50

    12.    Eugenia Ch Yiannakopoulou Pharmacogenomics and Opioid Analgesics: Clinical Implications Int J Genomics. 2015;2015:368979

    13.    Eugenia Ch Yiannakopoulou Targeting DNA Methylation with Green Tea Catechins Pharmacology. 2015 Mar 13;95(3-4):111-116

    14.    Eugenia Ch Yiannakopoulou Serious and long-term adverse events associated with the therapeutic and cosmetic use of botulinum toxin Pharmacology. 2015;95(1-2):65-9. doi: 10.1159/000370245. Epub 2015 Jan 21

    15.    Eugenia Ch Yiannakopoulou Pharmacovigilance for novel oral anticoagulants: why is it so crucial? J Pharmacovigilance 2015 in process

    16.    Eugenia Ch Yiannakopoulou Interaction of green tea catechins with breast cancer endocrine treatment: a systematic review Pharmacology. 2014;94(5-6):245-8. doi: 10.1159/000369170. Epub 2014 Nov 28

    17.    Eugenia Ch Yiannakopoulou Interaction of Salicylates and the Other Nonsteroidal Anti-Inflammatory Agents With Breast Cancer Endocrine Treatment: Systematic Review Am J Clin Oncol. 2014 Dec 10. [Epub ahead of print]

    18.    Yiannakopoulou E, Nikiteas N, Perrea D, Tsigris C Virtual reality simulators and training in laparoscopic surgery Int J Surg.  2015 Jan;13:60-4. doi: 10.1016/j.ijsu.2014.11.014. Epub 2014 Nov 18

    19.    Eugenia Ch Yiannakopoulou Aspirin and NSAIDs for breast cancer chemoprevention Eur J Cancer Prev. 2014 Nov 6. [Epub ahead of print]

    20.    Eugenia Ch Yiannakopoulou Targeting epigenetic mechanisms and microRNAs by aspirin and other non steroidal anti-inflammatory agents--implications for cancer treatment and chemoprevention Cell Oncol (Dordr). 2014 Jun;37(3):167-78.

    21.    Eugenia Ch Yiannakopoulou Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications. Cell Oncol (Dordr). 2014 Feb;37(1):1-8. doi: 10.1007/s13402-013-0158-0. Epub 2013 Dec 4

    22.    Eugenia Ch Yiannakopoulou Green tea catechins: Proposed mechanisms of action in breast cancer focusing on the interplay between survival and apoptosis Anticancer Agents Med Chem. 2014 Feb;14(2):290-5

    23.    Eugenia Ch Yiannakopoulou Pharmacovigilance and NSAIDs J Pharamcovigilance 2014  http://dx.doi.org/10.4172/2329-6887.1000e116

    24.    Eugenia Ch Υiannakopoulou Targeting oxidative stress response by green tea polyphenols: clinical implications Free Radic Res. 2013 Sep;47(9):667-71

    25.    Eugenia Ch Υiannakopoulou Effect of green tea catechins on breast carcinogenesis: a systematic review of in-vitro and in-vivo experimental studies Eur J Cancer Prev 2013 Aug 9

    26.    Eugenia Ch Υiannakopoulou , Nikolaos  Νikiteas , Despina Perrea ,  Christos Tsigris Effect of laparoscopic surgery on oxidative stress response: Systematic Review Surg Laparosc Endosc Percutan Tech. 2013 ;23(2):101-8

    27.    Υiannakopoulou Eugenia, Νikiteas Nikolaos, Perrea Despina, Tsigris Christos. Minimally invasive surgery and stress response Systematic review of animal data Surg Laparosc Endosc  Percutan Tech 2013; 3:101-8

    28.    Yiannakopoulou E Pharmacogenomics of acetylsalicylic acid and other nonsteroidal anti-inflammatory agents: clinical implications Eur J Clin Pharmacol In Press

    29.    Eugenia Ch Yiannakopoulou Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications  Pharmacogenomics J 2013 13:105-9

    30.    Eugenia Yiannakopoulou Does Pharmacodynamic Interaction of Non Enzymatic Antioxidants Modify Response to Anti-Oxidant Therapy in the Process of Atherosclerosis? J Cardiovasc Pharmacol 2012;17:366-72

    31.    Eugenia Yiannakopoulou Modulation of lymphangiogenesis: a new target for aspirin and other non steroidal anti-inflammatory agents? Systematic Review Clin Pharmacol. 2012;52:1749-54

    32.    Eugenia Ch Υiannakopoulou, Nikolaos  Νikiteas, Despina Perrea,  Christos Tsigris Pharmacological preconditioning of oxidative stress response: Systematic Review Surg Laparosc Endosc  Percutan Tech 2012 22;200-204

    33.    Eugenia Yiannakopoulou Pharmacogenomics of breast cancer targeted therapy: focus on recent patents Recent Pat DNA Gene Seq 2012;6:33-46

    34.    Eugenia Yiannakopoulou Recent patents on antibacterial, antifungal and antiviral properties of tea Recent Pat Anti-infect Drug Discov 2012;7:60-65

    35.    Eugenia Yiannakopoulou Botulinum toxin and anal fissure: Efficacy and safety-Systematic Review Int J  Colorectal Dis 2012;1:1-9

    36.    J Griniatsos, E. Yiannakopoulou, H. Gakiopoulou, A.Alexandrou, N. Dimitriou, I. Karavokyros, E. Felekouras Clinical implications of the histologically and immunohistochemically detected solitary lymph nodes metastases in gastric cancer Scand J Surg 2011;100:174-180

    37.    Yiannakopoulou E. Hemoptysis under diclofenac and antiplatelet doses of aspirin. Pharmacology 2011;87:1-4

    38.    Yiannakopoulou E Effect of aspirin in hemostasis: synergism or antagonism with non steroidal anti-inflammatory agents. IIOAB Journal 2010 1;29-32

    39.    Griniatsos J, Alexandrou A, Yiannakopoulou E A SIMPLE TECHNIQUE FOR VACUUM DRAINAGE OF THE PERITONEAL CAVITY IN THE MANAGEMENT OF ANASTOMOTIC LEAKS Accepted for publication in Journal of Buon

    40.    Yiannakopoulou E 7th Biennial Congress of the Mediterranean Society of Coloproctology (MSCP), Thessaloniki Greece, April, 22-24, 2010 Tech Coloproctol 2010;14:291-292

    41.    E. Yiannakopoulou and E. Tiligada Preconditioning effect of salicylates against oxidative stress in yeast. Journal of Applied Microbiology 2009;106:903-908

    42.    Ε.Yiannakopoulou Methodological issues regarding safety evaluation in randomized controlled trials of the effectiveness of antibiotic prophylaxis for the prevention of postoperative wound infection.  J Antimicrob Chemother  2009 ;63:843-845

    43.    Griniatsos J, Yiannakopoulou E, Tsehpenakis A, Tsigris Ch, Diamantis Th.  Α Hybride technique for recurrent incisional hernia repair. Surg Laparosc Endosc Percutan Tec 2009;19:e177-e180

    44.    Griniatsos J, Gakiopoulou H, Yiannakopoulou E, Dimitriou N, Douridas G, Nonni A, Liakakos Th, Felekouras E.  Routine modified D2 lymphadenectomy performance in pT1-T2N0 gastric cancer tumors World J Gastroenterol 2009;28:5568-5572 

    45.    Yiannakopoulou Eugenia Oxidative stress-antioxidant mechanisms-clinical implications Archives of Greek Medicine 2009;26:23-35

    46.    E. Yiannakopoulou Gynaecomastia and statins Epitheor Pharmacol Pharmacokinet 2009;27:19-22

    47.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Adherence to guidelines for antibiotic prophylaxis in general surgery: a critical appraisal. Journal of Antimicrobial Chemotherapy 2008;61:214-218

    48.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Surgical Site Infections Surveillance in general surgery: a critical issue Journal of Chemotherapy 2008;20:312-318 

    49.    E.Ch Yiannakopoulou Cephalosporin induced anaemia in surgical patients Review of Clinical Pharmacology and Pharmacokinetics International Edition 2008; 22:363-365

    50.    Ε.Ch Yiannakopoulou and E.Tiligada Pharmacological preconditioning in the oxidative stress response of eukaryotic cells: In process method validation Review of Clinical Pharmacology and Pharmacokinetics Greek Edition* 2007;25:30-32

    51.    C.E.Tourmousoglou, E.Ch.Yiannakopoulou, V.Kalapothaki, J.Bramis, J.St.Papadopoulos Antibiotic prophylaxis and adverse reactions of antibiotics in general surgery Review of Clinical Pharmacology and Pharmacokinetics International Edition 2006;20:338-340

    52.    Ε.Ch Yiannakopoulou and E.Tiligada Acetaminophen modulates the oxidative stress response in eucaryotic cells Review of Clinical Pharmacology and Pharmacokinetics International Edition 2006;20:125-127

    53.    Eugenia Ch.Yiannakopoulou, John S.Papadopulos, Dennis V. Cokkinos, Theodoros D. Mountokalakis Adherence to antihypertensive treatment: a critical factor for blood pressure control Eur J Cardiovasc Prev Rehabil 2005;12:243-249

    54.    E.Ch Yiannakopoulou, C.Damianou, C.Bamia, J.S.Papadopoulos Adequacy of safety data reporting in randomized clinical trials comparing coxibs with non-selective NSAIDs. Epitheor. Klin. Farmakol. Farmacokinet.* 2005;23:42-43

    55.     Ε.Ch.Yiannakopoulou, A.Delitheos, E.Tiligada  Dose-dependent effect of non-steroidal anti-inflammatory agents on the cellular stress response Epitheor. Klin. Farmacol. Farmakokinet.  2005;23:39-41

    56.    Τourmousoglou CE, Kalapothaki V, Yiannakopoulou E, Bramis J, Papadopulos JS Evaluating the adequacy of the prophylactic usage of antimicrobial drugs in surgical patients Review of Clinical Pharmacology and Pharmacokinetics International Edition* 2002;16: 27

    57.    E.Ch.Yiannakopoulou, J.S.Papadopulos, D.Cokkinos, T.Mountokalakis Side effects of antihypertensive medicines and how they influence the quality of treatment Review of Clinical Pharmacology and Pharmacokinetics, International Edition* 2002;16:109-110

    More Info.
    KWANG-HYUN BAEK
    Professor
    Department of Biomedical Science
    CHA University
    Korea
    baek@cha.ac.kr
    IJICR

    Kwang-Hyun Baek is a full professor of Department of Biomedical Science and a director of Cell & Gene Therapy Research Institute at CHA University in Korea. He received his Ph.D. from the department of Zoology and Genetics at Iowa State University in US in 1995 and worked as a postdoctoral research fellow in the division of Genetics at Brigham and Women’s Hospital and in the department of Pediatric Oncology at Dana-Farber Cancer Institute, Harvard Medical School. He has been serving as an editorial board member, a regional editor, and an editor-in-chief of many international journals. Current research and clinical interests are in the molecular genetics of ubiquitination and deubiquitination systems relevant to various cancers and stem cell proliferation/differentiation. He first coined terms ubiquitomics and deubiquitomics in the field of the ubiquitin-proteasome system. In addition, he is interested in genomics and proteomics during cancer cell proliferation and apoptosis.


    Grant Details:

    1) Korean Ministry of Health & Welfare: The prevention of high-risk pregnancy: Development of biomarkers for recurrent pregnancy loss using multi-omics. April 2018 ~ December 2020 ($350,000)

    2) Korea Research Foundation: Investigation of cellular mechanisms for DNA repair mediated by deubiquitinating enzymes and identification of their small molecules. June 2016 ~ May 2019 ($300,000)

    3) Korea Ministry of Environment: Screening and pathophysiology mechanisms of environmental risk factors for premature ovarian failure. May 2016 ~ December 2019 ($600,000)

    4) Korea Ministry of Science and Technology: BK21 Plus Program. September 2013 ~ August 2020 ($200,000 every year)"

    Publication List:

    1. Hiriyanna, K. T., Baedke, D., Baek, K.-H., Forney, B. A., Kordiyak, G., and T. S. Ingebritsen. (1994). Thiophosphorylated substrate analogs are potent active site-directed inhibitors of protein-tyrosine phosphatases. Anal. Biochem. 223: 51-58.

    *2. Baek, K.-H., and L. Ambrosio. (1994). An efficient method for microinjection of mRNA into Drosophila embryos. BioTechniques 17: 1024-1026. (Corresponding author)

    3. Baek, K.-H., Fabian, J., Sprenger, F., Morrison, D., and L. Ambrosio. (1996). The activity of D-raf in Torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev. Biol. 175: 191-204.

    *4. Baek, K.-H., and W. P. Hanratty. (1996). The characterization of temperature-sensitive lethal (2) giant larvae alleles in Drosophila melanogaster. Drosophila Infor. Serv. 77: 90-92. (Corresponding author)

    5. Johansen, K. M., Johansen, J., Baek, K.-H., and Y. Jin. (1996). Remodeling of nuclear architecture during the cell cycle in Drosophila embryos. J. Cell. Biochem. 63: 268-279.

    6. Radke, K., Baek, K.-H., and L. Ambrosio. (1997). Characterization of maternal and zygotic D-raf proteins: dominant negative effects on Torso signal transduction. Genetics 145: 163-171.

    *7. Baek, K.-H., and W. P. Hanratty. (1997). The l(2)gl, a recessive oncogene, is required during embryonic and post-embryonic development in Drosophila. Cancer Lett. 111: 233-238. (Corresponding author)

    8. Michelson, A. M., Gisselbrecht, S., Zhou, Y., Baek, K.-H., and E. M. Buff. (1998). Dual functions of the heartless fibroblast growth factor receptor in development of the Drosophila embryonic development. Dev. Genetics 22: 212-229.

    *9. Baek, K.-H. (1999). The first oncogene in Drosophila melanogaster. Mut. Res. 436: 131-136. (Corresponding author)

    *10. Baek, K.-H. (1999). The application of temperature-sensitive mutations in Drosophila. Arch. Pharm. Res. 22: 229-231. (Corresponding author)

    11. Jaster, R., Baek, K.-H., and A. D'Andrea (1999). Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the murine DUB-1 gene. Biochim. Biophys. Acta 1446: 308-316.

    *12. Baek, K.-H., and K. Y. Lee. (1999). Signal transduction pathway for anterior-posterior development in Drosophila. J. Biomed. Sci. 6: 314-319. (Corresponding author)

    *13. Baek K.-H., Kim M. K., Lee, K. Y., and K. Y. Cha (2000). Raf serine/threonine kinase is required for early embryogenesis in Drosophila. Kor. J. Genetics 22: 63-70. (Corresponding author)

    *14. Lee, J.-H., Kim, Y.-S., Kang, W.-P., and K.-H. Baek (2001). Temporal enzymatic activity of lymphocyte-specific deubiquitinating enzymes. Kor. J. Genetics 23: 3-6. (Corresponding author)

    *15. Baek, K.-H. (2001). Heartless, a fibroblast growth factor receptor, is  required for embryonic muscle development in Drosophila. Kor. J. Genetics 23: 151-156. (Corresponding author)

    *16. Lee, J.-H., Kim, M., Kim, Y.-S., and K.-H. Baek (2001). Critical regions for deubiquitinating activity of DUB-2 expressed in T lymphocytes. Am. J. Hematol. 67: 270-272. (Corresponding author)

    17. Baek, K.-H., Mondoux, M. A. Jaster, R., Fire-Levin, E., and A. D'Andrea (2001). DUB-2A, a new subfamily member of deubiquitinating enzymes. Blood 98: 636-642.

    *18. Choi, B. C., Kim, J. W., Lee, J., Yoo, K. J., Byun, H. K., Hwang, C. S., Moon, I. K., Kim, S. N., and K.-H. Baek (2001). The effect of exocelomic fluid in the first trimester pregnancy on trophoblast cell proliferation in vitro. Kor. J. Obs. Gyn. 44: 1678-1684. (Corresponding author)

    *19. Baek, K.-H., Kim., Y.-S., Jung, S., Lee, K.-Y., Choi, H.-K., and K.-S, Kim. (2002). Molecular cloning and characterization of bovine bgl-1, a novel family member of WD-40 repeat containing lethal giant lerval tumor suppressor genes. Int. J. Oncol. 20: 739-744.  (Corresponding author)

    *20. Baek, K.-H., Park, K.-H., Kim, Y.-S., Kim, M.-S., and H.-K. Choi. (2002). Molecular cloning and complete cDNA sequence of UBH1 in mouse testis. DNA Seq. 13: 145-148. (Corresponding author)

    *21. Kim, Y.-S., Baek, K.-H., Lee, K. Y., Jung, S., Chung, H.-M., Lee, K.-A., and K. Y. Cha. (2002). The rgl-1 is a legitimate homologue of lethal giant larvae recessive oncogene in rat. Int. J. Oncol. 20: 1219-1225.  (Corresponding author)

    *22. Baek, K.-H., Choi, B. C., Lee, J.-H., Choi, H.-K. Lee, S.-H., Kim, J.-W., Hill, J. A., Chung, H.-M., Ko, J. J., and K. Y. Cha. (2002). Comparison of gene expression at the feto-maternal interface between normal and recurrent pregnancy loss patients. Repro. Fertil. Dev. 14: 235-240. (Corresponding author)

    *23. Baek, K.-H., Kim., Y.-S., Chung, H. -M., Ko, J. J. and K. Y. Cha. (2002). Conservation of the lethal giant larvae tumor suppressor gene in Bos taurus coreanae. Kor. J. Genetics, 24: 127-132. (Corresponding author)

    *24. Baek, K.-H. (2002). Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines. Am. J. Hematol. 71: 340-345. (Corresponding author)

    *25. Lim, S.-K., Kim, M.-S., Lee, S.-H., and K.-H. Baek (2002). Polymorphism of CYP17 and CYP11a for polycystic ovary syndrome in a korean population. Kor. J. Genetics, 24: 343-348. (Corresponding author)
     
    *26. Baek, K.-H. (2003). Conjugation and deconjugation of ubiquitin regulating the destiny of proteins. Exp. Mol. Med. 35: 1-7. (Corresponding author)

    *27. Kim, Y.-S., Chung, H. M., and Baek, K.-H. (2003). WD-40 repeat containing rat lethal giant larvae recessive oncogene, but not tomosyn, restores the salt sensitivity in Saccharomyces cerevisiae. Int. J. Oncol. 23: 229-234. (Corresponding author)

    28. Chung, K.-H., Kim, S.-H., Han, K.-Y., Sohn, Y.-D., Chang, S.-I., Baek, K.-H., Kim, D.-S., and Kang, l. (2003). Inhibitory effect of salmosin, a Korean snake venom-derived disintegrin, on integrin av-mediated proliferation of SK-Mel-2 human melanoma cells. J. Pharm. Pharmacol. 55: 1577-1582.

    *29. Choi, H.-K., Choi, B. C., Lee, S.-H., Kim, J. W. Cha, K. Y., and Baek, K.-H. (2003). The expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol. Reprod. Dev. 66: 24-31. (Corresponding author)

    *30. Kim, Y.-S., Song, J., Kim, Y.-K., Kim, I.-O., Kang, I., and Baek, K.-H. (2003). Functional and expression analyses of mgl-1, a mouse orthologue of lethal giant larvae recessive oncogene. Int. J. Oncol. 23: 1515-1519. (Corresponding author)

    *31. Shin, J.-M., Kim, J.-W., Choi, B., Lee, S.-H., and Baek, K.-H. (2003). Expression of immunosuppression-related genes in fetal chorionic villi derived from recurrent spontaneous abortion patients. Kor. J. Fertil. Steril. 30: 233-240. (Corresponding author)

    32. Lee, K.-W., Jeong, Y.-M., Lee, S.-H., Yoon, T. K., Kwak, I. P., Yoon, S. W., Choi, J. S., Kim, K. H., Han, J. S., Kim, S. D., Kim, N. K., Cha, K. Y., Baek, K.-H., and Lee, S. (2003). The study of 5,10- methylenetetrahydrofolate reductase variation (MTHFR C677T) in fertile females with polycystic ovarian syndrome (PCOS) in Korea. Kor. J. Fertil. Steril. 30: 217-222.

    *33. Lim, S.-K., Shin, J.-M., Kim, Y.-S., and Baek, K.-H. (2004). Identification and characterization of murine mHAUSP encoding a deubiquitinating enzyme that regulates the status of p53 ubiquitination. Int. J. Oncol. 24: 357-364. (Corresponding author)

    *34. Baek, K.-H., Kim, M.-S., Kim, Y.-S., Shin, J.-M., and Choi, H.-K. (2004). DUB-1A, a novel subfamily member of deubiquitinating enzyme, is polyubiquitinated and cytokine-inducible in B lymphocytes. J. Biol. Chem. 279: 2368-2376. (Corresponding author)

    35. Jeon, S. Y., Baek, K.-H., Kim, Y.-S., Kwon, H. S., Ko, S. H., Song, K. -H., Yoo, S. J., Son, H. S., Cha, B. Y., Lee, K.W., Son, H. Y., Kang, S. K., and Yoon, K. H. (2004). Differentially up-regulated genes in proliferating porcine neonatal pancreas cells caused by epidermal growth factor. J. Cell. Biochem. 91: 354-364.

    36. Burrows, J. F., McGrattan, M. J., Rascle, A., Humbert, M., Baek, K.-H., and Johnston, J. A. (2004). DUB-3, a cytokine inducible deubiquitinating enzyme that blocks proliferation. J. Biol. Chem. 279: 13993-14000.

    *37. Baek, K.-H. (2004). Structural and functional conservation of the lgl recessive oncogenes. Int. J. Oncol. 24: 1257-1262. (Corresponding author)

    *38. Baek, K.-H. (2004). Aberrant gene expression associated with recurrent pregnancy loss. Mol. Hum. Reprod. 10: 291-297. (Corresponding author)

    *39. Kim, M.-S., Yoo, K.-J., Kang, I., Chung, H.M., and Baek, K.-H. (2004). A novel cysteine protease HeLa DUB-1 responsible for cleaving the ubiquitin in human cancer cells. Int. J. Oncol. 25: 373-379. (Corresponding author)

    *40. Kim, K.-S., Kim, M.-S., Kim, S.-K., and Baek, K.-H. (2004). Murine Asb-17 expression during mouse testis development and spermatogenesis. Zygote 12: 151-156. (Corresponding author)

    *41. Baek, K.-H., Kim, Y.-S., Lee, H.-J., and Kang, I. (2004). The essential regions for deubiquitinating enzyme activity and enhancer funciton for DUB-2A expressed in T-lymphocytes. Arch. Biochem. Biophys. 430: 191-197. (Corresponding author)

    *42 Kim, Y.-K., Kim, Y.-S., Chung, H.-M., and Baek, K.-H. (2004). Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes. Oncol. Rep. 12: 1105-1108. (Corresponding author)

    *43 Lee, H.-J., Yoo, K.-J., and Baek, K.-H. (2004). Structrual characterization of mouse HAUSP, a proteolysis regulator of p53. Kor. J. Biol. Sci. 8: 205-212. (Corresponding author)

    44. Hwang, K.R., Choi, Y.M., Choi, D.S., Baek, K.-H., Jeon, H.W., Bae, K.B., Son, Y.S., Ku, S.Y., Jee, B.C., Suh, C.S., Kim, S.H., Kim, J.G., and Moon, S.Y. (2004). Effect of metformin treatment and insulin resistance in patients with polycystic ovary syndrome. Kor. J. Obs. Gyn. 47: 1949-1953.

    *45. Kim, M.-S., Kim, Y.-K., Kim, Y.-S., Seong, M., Choi, J.-K., and Baek, K.-H. (2005). Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. Biochem. Biophys. Res. Commun. 330: 797-804. (Corresponding author)

    46. Lee, J., Choi, B.C., Cho, C., Hill, J.A, Baek, K.-H., and Kim, J.W. (2005).  Trophoblast apoptosis is increased in women with evidence of Th-1 immunity. Fertil. Steril. 83: 1407-1409.

    *47. Yoo, K.-J., Lee, H.-J., Lee, H., Lee, K.-Y., Lee, S.-H., Chung, H.-M., and Baek, K.-H. (2005). Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells. Int. J. Oncol. 27: 97-104. (Corresponding author)

    *48. Kim, Y.-K., Kim, Y.-S., and Baek, K.-H. (2005). The WD-40 repeat motif of Lgl tumor suppressor proteins associated with salt tolerance and temperature sensitivity. Biochem. Biophys. Res. Commun. 331: 922-928. (Corresponding author)

    *49. Lee, E.-J., Yoo, K.-J., Kim, S.-J., Lee, S.-H., Choi, D.-H., Cha, K.-.Y., Choi, D.-S., and Baek, K.-H. (2005). Relationship between the C/T single nucleotide polymorphism in exon 17 of the insulin receptor gene and polycystic ovary syndrome. J. Biol. Sci. 5: 832-836. (Corresponding author)

    50. Kang, I.-C., Min, B., Ahn, E., Son, H., and Baek, K.-H. (2005). Expression of soluble recombinant integrin alpha V and beta 3 from SF21 cells with baculovirus expression vector for targeted screening of integrin antagonists. Kor. J. Genetics 27: 211-217.

    *51. Lee, H.-J., Kim, M.-S., Kim, Y.-K., Oh, Y.-K., and Baek, K.-H. (2005). HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated,  polyneddylated, and dimerized. FEBS Lett. 579: 4867-4872. (Corresponding author)

    *52. Seong, M., Kim, M.-S., Kim, Y.-S., Lee, S.-H., Lee, H.-J., Cha, K.-Y., and Baek, K.-H. (2005). HIDE, a testis specific deubiquitinating enzyme, interacts with HSP90. Kor. J. Fertil. Steril. 32: 231-242. (Corresponding author)

    *53. Lee, M.-Y., and Baek, K.-H. (2005). Regulation of insulin signaling through protein degradation. Kor. J. Endocrinol. 20: 434-440. (Corresponding author) 

    *54. Baek, K.-H. Lee, H.-J., Kim, M.-S., Kim, Y.-S., Lee, E.-J., and Lee, M.-Y. (2006). Molecular cloning of rHAUSP encoding a deubiquitinating enzyme in a rat testis. Oncol. Rep. 15: 173-177. (Corresponding author)

    *55. Lee, H.-J., Kim, M.-S., Shin, J.-M., Park, T.-J., Chung, H.-M., and Baek, K.-H. (2006). The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Mech. Dev. (Gene Exp. Patterns) 6: 277-284. (Corresponding author)

    56. Gu, Y.-M., Jin, Y.-H., Choi, J.-K., Baek, K.-H., Yeo, C.-Y., and Lee, K.-Y. (2006). Protein kinase A phosphorylates and regulates dimerization of 14-3-3 zeta. FEBS Lett. 580: 305-310.

    *57. Baek, K.-H. (2006). Cytokine-regulated degradation by the ubiquitination system. Curr. Protein Pept. Sci. 7: 171-177. (Corresponding author)

    *58. Lee, E.-J., Yoo, K.-J., Kim, S.-J., Lee, S.-H., Cha, K.Y., and Baek, K.-H. (2006). Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertil. Steril. 86: 380-385. (Corresponding author)

    *59. Cheon, K.-W., and Baek, K.-H.  (2006). HAUSP as a therapeutic target for hematopoietic tumors. Int. J. Oncol. 28: 1209-1215. (Corresponding author)

    *60. Kim, Y.-S., Kim, M.-S., Lee, S.-H., Choi, B.-C., Lim, J.-M., Cha, K.-Y., and Baek, K.-H. (2006). Proteomic analysis of recurrent spontaneous abortion: identification of an inadequately expressed set of proteins in human follicular fluid. Proteomics, 6: 3445-3454. (Corresponding author)

    *61. Kim, Y.-S., Kim, Y.-K., Park, J.-M., Han, I.-S., Ajjappala, B.S., Kang, I., and Baek, K.-H.  (2006). Disruption of protein-protein interaction for Mgl-1 oncoprotein. Oncol. Rep. 16: 795-800. (Corresponding author)

    62. Kim, S.-J., Lee, S.-Y., Lee, C., Kim, I., An, H.-J., Kim, J.-Y., Baek, K.-H., Kim, E.-J., Kim J.-M., Lee, J.-B., Lee, J.-W., Jung, W.-W., Chun, T., and Oh, Y.-K. (2006). Differential expression profiling of genes in a complete hydatidiform mole using cDNA microarray analysis. Gynecol. Oncol. 103: 654-660.

    *63. Shin, J.-M., Yoo, K.-J., Kim, M.-S., Kim, D., and Baek, K.-H.  (2006). Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. BMC Genomics 7: 292. (Corresponding author)

    64. Park, J.-E, Jang, M.-H., Cho, S.-W., Kim, Y.-S., Won, H.-J., Cho, J.-H., Baek, K.-H., and Lee, S.-H. (2006). Mitochondrial DNA copy number in the patients of Korean polycystic ovary syndrome (PCOS). Kor. J. Fertil. Steil. 33: 245-251.

    *65. Kim, Y.-K., Kim, Y.-S., Yoo, K.-J., Lee, H.-J., Lee, D.-R., Yeo, C.Y., and Baek, K.-H.  (2007). The expression of Usp42 during embryogenesis and spermatogenesis in mouse. Mech. Dev. (Gene Exp. Patterns) 7: 143-148.  (Corresponding author)

    *66. Noh, S.M., Kim, W.-K., Kim, S.J., Kim, J.M., Baek, K.-H., and Oh, Y.-K. (2007). Enhanced cellular delivery and transfection efficiency of plasmid DNA using positively charged biocompatible colloidal gold nanoparticles. Biochim. Biophys. Acta 1770: 747-752. (Corresponding author)

    *67. Baek, K.-H., Lee, E.-J., and Kim, Y.-S. (2007). Recurrent pregnancy loss: the key possible mechanisms. Trends Mol. Med. 13: 310-317. (Corresponding author)

    *68. Kim, D.C., Noh, S.M., Park, K.T., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2007). Transdermal delivery of porcine placenta extracts using linolenic acid-based emulsion formulations. J. Kor. Pharm. Sci. 37: 281-286. (Corresponding author)

    *69. Park, J.-M., Gu, B.-H., Lee, E.-J., Kim, J.-Y., Choi, S.-W., and Baek, K.-H. (2008). A single nucleotide polymorphism in exon 7 of sorbin and SH3-domain-containing-1 (SORBS1) in Korean PCOS patients. Mol. Med. Rep. 1: 93-97. (Corresponding author)

    70. Jin, Y.-H., Kim, Y.-J., Kim, D.-W., Baek, K.-H., Kang, B. Y., Yeo, C.-Y., and Lee, K.-Y. (2008). Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53. Biochem. Biophys. Res. Commun. 368: 690-695.

    *71. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Lee, S.-H., and Baek, K.-H. (2008). A single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil. Steril. 89: 1213-1220. (Corresponding author)

    *72. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Park, J.-M., and Baek, K.-H. (2008). Association study between single nucleotide polymorphisms in the VEGF gene and polycystic ovary syndrome (PCOS). Fertil. Steril. 89: 1751-1759. (Corresponding author)

    *73. Park, J.-M., Lee, E.-J., Ramakrishna, S., Cha, D.-H., and Baek, K.-H. (2008). Association study for single nucleotide polymorphisms in CYP17A1 gene and polycystic ovary syndrome. Int. J. Mol. Med. 22: 249-254. (Corresponding author)

    *74. Kim, D.C., Noh, S.M., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2008). Transdermal delivery of ceramide using sodium deoxycholate-based deformable liposomes. J. Kor. Pharm. Sci. 38: 319-323. (Corresponding author)

    *75. Lee, M.-Y., Ajjappala, B.S., Kim, M.-S., Oh, Y.-K., and Baek, K.-H. (2008). DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway. J. Cell. Biochem. 105: 1420-1429. (Corresponding author)

    *76. Ajjappala, B.S., Kim, Y.-S., Kim, M.-S., Lee, M.-Y., Lee, K.-Y., Ki, H.-Y., Cha, D.-H., and Baek, K.-H. (2009). 14-3-3γ is stimulated by IL-3 and promotes cell proliferation. J. Immunol. 182: 1050-1060. (Corresponding author)

    *77. Gu, B.H., and Baek, K.-H. (2009). Pro12Ala and His447His polymorphisms of PPAR-gamma are associated with polycystic ovary syndrome. Reprod. BioMed. Online, 18: 644-650. (Corresponding author)

    78. Ait-Ali, T., Wilson, A.W., Finlayson, H., Carre, W., Ramaiahgari, S.C., Westcott, D.G., Waterfall, M., Frossard, J.P., Baek, K.-H., Drew, T.W., Bishop, S.C., and Archibald, A.L. (2009). Functional analysis of the porcine USP18 and its role during porcine arterivirus replication. Gene 439: 35-42.
    *79. Choi, S.-W., Gu, B.-H., Ramakrishna, S., Park, J.-M., and Baek, K.-H. (2009). Association between a single nuclotide polymorphism in MTHFR gene and polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 145: 85-88. (Corresponding author)
    *80. Ajjappala, B., Kim, M.-S., Kim, E.-Y., Kim, J.-H., Kang, I.-C., and Baek, K.-H. (2009). Protein chip analysis of pluripotency associated proteins in NIH3T3 fibroblast. Proteomics 9: 3968-3978. (Corresponding author)
    81. Jo, A.-Y., Kim, M.-Y., Lee, H.-S., Rhee, Y.-H., Lee, J.-E., Baek, K.-H., Park, C.-H., Koh, H.-C., Shin, I., Lee, Y.-S., and Lee, S.-H. (2009). Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant Nurr1 mutant. Stem Cells 27: 2238-2246.
    *82. Gu, B.-H., and Baek, K.-H. (2009). Follicular-stimulating hormone receptor (FSHR) polymorphisms and polycystic ovary syndrome (PCOS). Fertil. Steril. 92: e55. (Corresponding author)

    *83. Baek, K.-H., and Ramakrishna, S. (2009). USP7 (ubiquitin specific peptidase 7 (herpes virus-associated)). Atlas Genet Cytogenet Oncol Haematol. 2009; 13(8): 576-579. (Corresponding author)

    84. Noh, S.M., Park, M.O., Shim, G., Han, S.E., Lee, H.Y., Huh, J.H., Kim, M.S., Bang, S.S., Kim, K., Kwon, I.C., Kim, J.-S., Baek, K.-H., and Oh, Y.-K. (2010). Pegylated poly-L-arginine derivatives of chitosan for effective delivery of siRNA. J. Control. Release, 145: 159-164.

    *85. Ramakrishnam, S., Suresh, B., Kang, I.-C., and Baek, K.-H. (2010). Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme. Hybridoma, 29: 311-319. (Corresponding author)

    *86. Choi, J.-H., Lee, M.-Y., Kim, Y., Shim, J.-Y., Han, S.-M., Lee, K.-A., Choi, Y.-K., Jeon, H.-M., and Baek, K.-H. (2010). Isolation of genes involved in pancreas regeneration by subtractive hybridization. Biol. Chem. 391: 1019-1029. (Corresponding author)

    *87. Gu, B.-H., Park, J.-M., and Baek, K.-H. (2010). Genetic variations of FSHR are associated with polycystic ovary syndrome. Int. J. Mol. Med. 26: 107-112. (Corresponding author)

    *88. Suresh, B., Ramakrishna, S., Lee, H.-J., Choi, J.-H., Kim, J.-Y., Ahn, W.-S., and Baek, K.-H. (2010). K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44. Cell Biol. Int. 34: 799-808.  (Corresponding author)

    *89. Suresh, B., Ramakrishna, S., Kim, Y.-S., Kim, S.-M., Kim, M.-S., and Baek, K.-H. (2010). Stability and function of mammalian lethal giant larvae-1 oncoprotein are regulated by the scaffolding protein RanBPM. J. Biol Chem. 285: 35340-35349. (Corresponding author)

    *90. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2011). The role of deubiquitinating enzymes in apoptosis. Cell. Mol. Life Sci. 68: 15-26. (Corresponding author)

    *91. Lan, L., Yun, J.-H., Lee, J.-H., Song, S., Choi, B.-C., and Baek, K.-H. (2011). Association study of +45G15G (T/G) and +276 (G/T) polymorphisms in the adiponectin gene with polycystic ovary syndrome. Int. J. Mol. Med. 27: 283-287. (Corresponding author)

    *92. Kim, M.-S., Ramakrishna, S., Lim, K.-H., Kim, J.-H., and Baek, K.-H. (2010). Protein stability of mitochondrial superoxide dismutase SOD2 is regulated by USP36. J. Cell. Biochem. 112: 498-508. (Corresponding author)

    *93. Ramakrishna, S., Suresh, B., Lee, E.-J., Lee, H.-J., Ahn, W.-S., and Baek, K.-H. (2011). Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J. Biol. Chem. 286: 10505-10514. (Corresponding author)

    *94. Kim, M.-S., Gu, B.-H., Song, S., Choi, B.-C., Cha, D.-H., and Baek, K.-H. (2011). ITI-H4, as a biomarker in the serum of recurrent pregnancy loss patients. Mol. Biosyst. 7: 1430-1440. (Corresponding author)

    *95. Kim, J.-H., Li, L., Yun, J.-H., Choi, B.-C., and Baek, K.-H. (2011). Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome. Mol. Med. Rep. 4: 747-751. (Corresponding author)

    *96. Ramakrishna, S., Suresh, B., Lim, K.-H., Cha, B.-H., Lee, S.-H., Kim, K.-S., and Baek, K.-H. (2011). PEST motif sequence regulating human NANOG for proteasomal degradation. Stem Cells Dev. 20: 1511-1519.  (Corresponding author)

    97. Bang, J.-Y., Kim, E.-Y., Kang, D.-K., Chang, S.-I., Han, M.-H., Baek, K.-H., and Kang, I.-C. (2011). Pharmaco-proteomic analysis of a novel cell-permeable peptide inhibitor of tumor-induced angiogenesis. Mol. Cell. Proteomics, Mol. Cell. Proteomics, 10: M110.005264

    *98. Choi, J.-H., Lee, M.-Y., Ramakrishna, S., Kim, Y., Shim, J.-Y. Han, S.-M., Kim, J.-Y., Lee, D.-H., Choi, Y.-K., and Baek, K.-H. (2011). LCP1 up-regulated by partial pancreatectomy supports cell proliferation and differentiation. Mol. BioSyst. 7: 3104-3111. (Corresponding author)

    *99. Yun, J.-H., Choi, J.-W., Lee, K.-J.,Shin, J.-S., and Baek, K.-H. (2011). The promoter -1031(T/C) polymorphism in tumor necrosis factor-alpha associated with polycystic ovary syndrome. Reprod. Biol. Endocrinol. 9: 131. (Corresponding author)

    *100. Baek, K.-H., and Suresh, B. (2012). RANBP9 (RAN binding protein 9). Atlas Genet Cytogenet Oncol Haematol. 2009; 16 (8): 549-551. (Corresponding author)

    *101. Suresh, B., Ramakrishna, S., and Baek, K.-H. (2012). Diverse roles of a scaffolding protein RanBPM. Drug Discov. Today, 17: 379-387. (Corresponding author)

    *102. Ramakrishna, S., Suresh, B., Bae, S.-M., Ahn, W.-S., Lim, K.-H., and Baek, K.-H. (2012). Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity. PLoS One, 7: e37772. (Corresponding author)

    *103. Yun, J.-H., Gu, B.-H., Kang, Y.-B., Choi, B.-C., Song, S., and Baek, K.-H. (2012). Association between INS-VNTR polymorphism and polycystic ovary syndrome in a Korean population. Gynecol. Endocrinol, 28: 525-528. (Corresponding author)

    *104. Baek, K.-H., Lee, H., Yang, S., Lim, S.-B., Lee, W., Lee, J.E., Lim, J.-J., Jun, K., Lee, D.-R., Chung, Y. (2012). Embryonic demise caused by targeted disruption of a cysteine protease Dub-2. PLoS One, 7: e44223. (Corresponding author)

    *105. Choi, J.-H., Lim, K.-H., Park, E., Kim, J.-Y., Choi, Y.-K., and Baek, K.-H. (2012). Glutamate-ammonia ligase and reduction of G0 population in PANC-1 cells. J. Cell. Biochem. 114(2): 303-313. (Corresponding author)

    *106. Kim, Y.-S., Gu, B.-H. Choi, B.-C. Kim, M.-S., Song, S., Yun, J.-H., Chung, M.-K., Choi, C.-H., and Baek, K.-H. (2012). Apolipoprotein A-IV as a novel gene associated with polycystic ovary syndrome. Int. J. Mol. Med. 31(3): 707-716. (Corresponding author)

    *107. Lim, K.-H., and Baek, K.-H. (2012). Deubiquitinating enzymes as therapeutic targets in cancer. Curr. Pharm. Des. 19(22) 4039-4052. (Corresponding author)

    *108. Park, J.-J., Yun, J.-H., and Baek, K.-H. (2013). Polyclonal and monoclonal antibodies for ubiquitin specific protease 20. Mono. Ant. Immuno. Immunoth. 32(3): 193-199. (Corresponding author)

    *109. Lim, K.-H., Ramakrishna, S., and Baek, K.-H. (2013). Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes. Cyt. Growth Factor Rev. 24(5): 427-431. (Corresponding author)

    *110. Li, L., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2013). Relationship between leptin receptor and polycystic ovary syndrome. Gene, 527(1): 71-74. (Corresponding author)

    111. Lee, K.W., Cho, J.G., Kim, C.M. Kang, A.Y., Kim, M., Ahn, B.Y., Chung, S.S., Lim, K.-H., Baek, K.-H., Park, K.S., Sung, J.-H., and Park, S.G. (2013). Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor gamma (PPARr) stability through its deubiquitinating activity. J Biol Chem, 288(46): 32886-32896.

    *112. Lim, K.-H., Kim, S.-R., Ramakrishna, S., and Baek, K.-H. (2014). Critical lysine residues of Klf4 required for protein stabilization and degradation. Biochem. Biophys. Res. Commun. 443(4): 1206-1210. (Corresponding author)

    *113. Ramakrishna, S., Kim, K.-S., and Baek, K.-H. (2014). Posttranslational modifications of defined embryonic reprogramming transcription factors. Cell Reprogram. 16(2): 108-120. (Corresponding author)

    *114. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2015). Biological functions of hyaluronan and cytokine-inducible deubiquitinating enzymes. BBA - Rev. Cancer, 1855: 83-91 (Corresponding author)

    *115. Park, J.-J., Lim, K.-H., and Baek, K.-H. (2015). Annexin-1 regulated by HAUSP is essential for UV-induced damage response. Cell Death & Dis. 6:e1654. (Corresponding author)

    *116. Kim, S.-R., Kim, J.-O., Lim, K.-H., Yun, J.-H., and Han, I., and Baek, K.-H. (2015). Regulation of pyruvate kinase isozyme M2 is mediated by the ubiquitin-specific protease 20. Int. J. Oncol. 46: 2116-2124. (Corresponding author)

    *117. Li, L., Yun, J.-H., Yoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). 54G/C polymorphism of SREBF-1 gene is associated with polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 188: 95–99. (Corresponding author)

    *118. Park, J.-H., Li, L., and Baek, K.-H. (2015). Association of T869C polymorphism of transforming growth factor-β1 gene with polycystic ovary syndrome. Mol. Med. Rep. 12(3): 4560-4565. (Corresponding author)

    *119. Li, L., and Baek, K.-H. (2015). Molecular genetics of polycystic ovary syndrome: an update. Curr. Mol. Med. 15(4): 331-342. (Corresponding author)

    *120. Li, L., Ryoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). Genetic Variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome. PLoS One. 10(4): e0123045. (Corresponding author)

    121. Schvartz, D., Bergsten, P., Baek, K.-H.. Barba De La Rosa, A., Cantley, J., Dayon, L., Finamore, F., Fontana, P., Gaudet, P., Goo, Y.A., Moulder, R., Goodlett, D., Johnson, J.D., Konvalinka, A., Mulde,r H., Priego-Capote, F., Sechi, S., Snyder, M., Tiss, A., Wiederkehr, A., Xenarios, I., Kussmann, M., and Sanchez, J-C. (2015). The human diabetes proteome project (HDPP): The 2014 update. Translational Proteomics. 8-9: 1-7.

    *122. Lim, K.-H., Park, J.-J., Gu, B.-H., Kim, J.-O, Park, S.-G, and Baek, K.-H. (2015). HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response. Sci. Rep. 5: 12793. (Corresponding author)

    *123. Kim, J.-O,, Kim, S.-R., Lim, K.-H., Kim, J.-H., Ajjappala, B., Lee, H.-J., Choi, J.-I., and Baek, K.-H. (2015). Deubiquitinating enzyme USP37 regulating oncogenic function of 14-3-3γ. Oncotarget, 6(34): 36551-36576. (Corresponding author)

    124. Kim, K. E., Cho, Y. S., Baek, K. S., Li, L., Baek, K.-H., Kim, J. H., Kim, H.-S., Sheen, Y. H. (2016). Lipopolysaccharide-binding protein plasma levels as a biomarker of obesity-related insulin resistance in adolescents. Kor. J. Pediatr. 59(5): 231-238.

    125. Ahn, H.-J., Kim, K.-S., Shin, K.-W., Lim, K.-H., Kim, J.-O., Lee, J.-Y., Kim, J., Park, J.-H., Yang, K.-M., Baek, K.-H., Ko, J.-J., and Park, K.-S. (2016). Ell3 induces p53 stabilization following CDDP treatment by modulating ubiquitin-dependent and -independent proteasomal degradation pathways in the breast cancer cells. Oncotarget, 6(42): 44523-44537.

    *126. Lim, K.-H., Song, M.-H., and Baek, K.-H. (2016). Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint. Cell Mol Life Sciences, 73(7): 1439-1455. (Corresponding author)

    *127. Lim, K.-H., Suresh, B., Park, J.-H., Kim, Y.-S., Ramakrishna, S., and Baek, K.-H. (2016). Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth. Oncotarget, 7(22): 14441-14457.

    128. Chung, S., Rho, S., Kim, G., Kim, S.-R., Baek, K.-H., Kang, M., and Lew, H. (2016). Human cord blood cells and chorionic plate-derived mesenchymal stem cells promote axon survival in an optic nerve crush rat model. Int. J. Mol. Med. 37(5): 1170-1180.

    *129. Baek, K.-H. (2016). Meet Our Editorial Board Member. Curr. Protein & Pept. Sci. 17(4): 1.

    *130. Lim, K.-H., Choi, J.-H., Park, J.-H., Cho, H.-J., Park, J.-J., Lee, E.-J., Li, L., Choi, Y.-K., and Baek, K.-H. (2016). Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A. Oncotarget, 7(23): 34759-34772.

    *131. Park, J.-H., Li, L., Choi, J.-W., and Baek, K.-H. (2016). The association of-429T>C and -374T>A polymorphisms in the RAGE gene with polycystic ovary syndrome. Int. J. Med. Sci. 13(6): 451-456.

    *132. Kwon, S.-K., Lee, D.-H., Kim, S.-Y., Park, J.-H., Choi, J.-H., and Baek, K.-H. (2017). Ubiquitin-specific protease 21 regulating the K48-linked polyubiquitination of NANOG. Biochem. Biophys. Res. Commun. 482: 1443-1448..

    *133. Kwon, S.-K., Kim, E.-H., and Baek, K.-H. (2017). RNPS1 is modulated by ubiquitin-specific protease 4. FEBS Lett. 591(2): 369-381.

    134. Kim, Y.-J., Hur, J., Cho, E.-H., Baek, K.-H., and Lee, K.-J. (2017). Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum. Int. J. Med. Sci. 14(2): 123-127.

    *135. Kwon, S.-K., Saindane, M., and Baek, K.-H. (2017). p53 stability is regulated by diverse deubiquitinating enzymes. BBA - Rev. on Cancer, 1868: 404-411 (Corresponding author)

    *136. Kim, S.-Y., Kwon, S.-K., Lee, S.-Y., and Baek, K.-H. (2018). Ubiquitin-specific protease 5 and OTU deubiquitinase 6A differentially expressed by the expression level of p53. Int. J. Oncol. 552: 1705-1714. (Corresponding author)

    137. Kim, J.H., Heo, J.S., Baek, K.S., Kim, S.-Y., Kim, J.H., Baek, K.-H., Kim, K.E., and Sheen, Y.H. (2018). Zonulin level, a marker of intestinal permeability, is increased in association with liver enzymes in young adolescents. Clin. Chim. Acta 481: 218-224.

    *138. Choi, J., and Baek, K.-H. (2018). Cellular functions of stem cell factors mediated by the ubiquitin-proteasome system. Cell. Mol. Life Sci. 75: 1947-1957. (Corresponding author)

    *139. Kim, S.-Y., Choi, J., Lee, D.-H., Park, J.-H., Hwang, Y.-J., and Baek, K.-H. (2018). PME-1 is regulated by USP36 in ERK and Akt signaling pathways. FEBS Lett. 592(9): 1575-1588. Corresponding author)

    140. Baek, K.-H. (2018). Regulation of protein degradation and homeostasis by the cytokine-inducible deubiquitinating enzymes. Int. J. Immunother Cancer Res. 4: 1-3. (Corresponding author)

    141. Kim, K.E., Heo, J. S., Han, S., Kwon, S.-K., Kim, S.-Y., Kim, J.H., Baek, K.-H., and Sheen, Y. H. (2018). Blood concentrations of lipopolysaccharide-binding protein, high-sensitivity C-reactive protein, tumor necrosis factor-α, and Interleukin-6 in relation to insulin resistance in young adolescents. Clin. Chim. Acta 486: 115-121.

    *142. Li, L., Choi, B.-C., Ryoo, J.E., Song, S.-J., Pei, C.-Z., Lee, K.Y., Paek, J., and Baek, K.-H. (2018). Opposing roles of inter--trypsin inhibitor heavy chain 4 in recurrent pregnancy loss. EBioMedicine, in press.


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    Armando Varela
    Professor
    Department of Biological Sciences
    University of Texas
    USA
    avarela2@utep.edu
    IJICR

    Research Interest: Anti-Cancer, Apoptosis, Blebbing, Caspases, Cell Cycle, Cell Signaling, Cancer, DNA Fragmentation, Drug Discovery, Flow Cytometer, Intrinsic and extrinsic apoptosis pathway, Laser Confocal Microscope, Mitochondrial Depolarization and Necrosis.

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    David R. Minor
    Associate Director
    California Pacific Center for Melanoma Research and Treatment
    University of California, San Francisco
    USA
    minord@sutterhealth.org
    IJICR

    Research Interest: Melanoma, kidney cancer , immunotherapy with ipilimumab, nivolumab, interleukin-2 and other agents. 

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    Fei Tang
    Research Associate
    Center for Cancer and Immunology Research
    Childrens National Medical Center
    USA
    tangflying@gmail.com
    IJICR

    Research Interest: 1) mTOR signaling, inflammation and hematopoiesis; (2) Neoplasm, hematologic cancers and related disorders; (3) Experimental cancer biology and clinical oncology; (4) Molecular mechanisms regulating hematopoietic stem cells function; (5) Molecular mechanisms involved in T / B / myeloid/erythroid cells developments; (6) Ubiquitination, apoptosis and selective autophagy.

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    Guozheng Liu
    Associate Professor
    Department of Radiology
    University of Massachusetts Medical Schoo
    USA
    Guozhengliu@yahoo.com
    IJICR

    Research Interest: Radiopharmaceutical development that involves radiolabeled agents and their evaluations both in vitro and in vivo. These agents are for disease detection, life process tracing, or tumor radiotherapy.

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    LV Rao
    Professor
    Department of Clinical Pathology
    UMass Memorial Health Care
    USA
    Lokinendi.Rao@umassmemorial.org
    IJICR

    Research Interest: Lab Medicine, Clinical Chemistry, Endocrinology and Immunology.

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    Luis Corrales-Rodriguez
    Assistant Professor
    Medical Oncology Residency
    University of Costa Rica
    Central America
    corrales@cimcacr.com
    IJICR

    Research Interest: Thoracic Oncology, Translational Research, Immuno-Oncology

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    Maurizio Chiriva Internati
    Associate Professor
    Department of Internal Medicine
    University Texas Health Sciences Center
    USA
    Maurizio.Chiriva@ttuhsc.edu
    IJICR

    Research Interest: These cancers express unique tumor-specific or -associated antigens to which my lab directs T cell immune responses via DNA, RNA, protein or peptide based vaccines.  Vaccine components are delivered in their native form, by dendritic cells, by recombinant Adeno Associated Virus.  This clinically translational research is backed up by pre-clinical and basic research in both normal and transgenic animal models and in laboratory studies on patient material. Results from the pre-clinical studies have led to a variety of clinical trials for which I am the immunological coordinator. 

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    Mayordomo Jose Ignacio
    Professor
    Division of Medical Oncology
    University of Colorado
    USA
    josemayordomo@hotmail.com
    IJICR

    Research Interest: Cancer immunotherapy, antigen presentation, dendritic cells, costimulatory molecule AND cancer vaccine.

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    Rasika Rohatgi
    Researcher
    Cancer Biology
    University of Massachusetts Medical School
    USA
    rasikarohatgi@gmail.com
    IJICR

    Research Interest: Molecular mechanisms  and  signaling  pathways  underlying  cancer  progressi on,  metastasis and chem resistance

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    Robert John Amato
    Professor
    Department of Internal Medicine
    University of Texas Health Science Center
    USA
    robert.amato@uth.tmc.edu
    IJICR

    Research Interest: Oncology, urologic oncology, targeted therapy, cancer genomics and prostate cancer.

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    Sandeep Kumar
    Professor
    Roswell Park Cancer Institute
    USA
    sandeep_sant@yahoo.co.in
    IJICR

    Research Interest: Cytokines, Allergy and Tumor Immunology.

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    Steve A Maxwell
    Associate Professor
    Department of Molecular and Cellular Medicine
    Texas A&M Health Science Center
    USA
    smaxwell@medicine.tamhsc.edu
    IJICR

    Research Interest: Cancer Genetics, Apoptosis, Oncogenes, Tumor Suppressor Genes, Mechanisms of Anti-Cancer Drug Resistance.

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    Sunandan Saha
    Scientist
    Department of Medicine
    Bellicum Pharmaceuticals
    USA
    ssaha@bellicum.com
    IJICR

    Research Interest: My research interest involves finding innovative gene therapy solutions for human diseases. At Bellicum, Pharmaceuticals, I have played a leading role in the discovery and pre-clinical development of the CIDeCAR and Go-CART product portfolios. Prior to Bellicum, I was a trainee at Baylor College of Medicine where I developed a novel platform for delivery of erythropoietin to treat anemia associated with chronic kidney disease and evaluated the safety of the piggyBac gene delivery system for gene and cell the rapy. I have extensive research experience in immunotherapy of leukemias and solid tumors, adoptive transfer of T cells, T cell biology, tumor infiltrating lymphocytes, immune receptors biology, antigen processing and recognition, antibody therapy, tumor immunology, viral and non-viral vectors, and gene therapy of monogeneic disorders. I have comprehensive knowledge of molecular biology research techniques including genetic engineering, vector design, cloning, transfection platforms,

    cytometry, biomarker development and validation and synthetic DNA construction 

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    Jens Hahne
    Scientist
    Molecular Pathology
    Institute of Cancer Research
    UK
    hahnejen@yahoo.de
    IJICR

    Research Interest: Tumours Role of transcription factors for angiogenesis, tumour invasion and metastasis Interaction of tumour cells and cells of the tumour stroma Translational research Molecular targeting therapy Biochemical, immunological and pharmacological assays for characterization of the efficacy of different therapeutic agents Tumour immunology Immune evasion mechanism of tumour cells.

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    Ji-Liang Li
    Professor
    Cancer Immunology
    Plymouth University
    UK
    ji-liang.li@imm.ox.ac.uk
    IJICR

    Research Interest: Tumour Microenvironment and Translational Cancer Medicine

     Combination of cancer target therapy and immunotherapy

     Tumour associated macrophages

     Notch signalling in cancer biology

     Tumour resistance to target therapy and immunotherapy

     Hypoxia and angiogenesis pathways in cancer biology

     MicroRNAs in cancer target therapy and immunotherapy

     Experimental mouse tumour models

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    Amedeo Amedei
    Associate Professor
    Department of Experimental and Clinical Medicine
    University of Florence, Firenze
    Italy
    aamedei@unifi.it
    IJICR

    Research Interest: Immunology, Cancer, ImmunoTherapy, Autoimmunity

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    Monica Rinaldi
    Research Scientist
    Department of BioMedicine
    National Research Council
    Italy
    monica.rinaldi@ift.cnr.it
    IJICR

    Research Interest: Development of new DNA vaccines and adjuvants for anticancer therapy and/or prevention, intended for clinical application. Preclinical protocols of genetic immunization against tumor-associated antigens Combined therapeutic protocols (vaccination+immunotherapy+chemotherapy) in preclinical research.

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    Barbara Wollenberg
    Professor
    Department of Otorhinolaryngology
    Universitatsklinikum Schleswig-Holstein
    Germany
    Barbara.Wollenberg@uksh.de
    IJICR

    Research Interest: Head and neck oncology, molecular as well as clinically molecular rhinology

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    Houria Boulaiz Tassi
    Professor
    Department of Human Anatomy and Embriology
    University of Granada
    Spain
    hboulaiz@ugr.es
    IJICR

    Research Interest: Cancer therapy, cancer stem cells, tumour biomarkers, suicide gene therapy and antitumoral drugs, nanotechnology and regenerative medicine.

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    Jesus M Paramio
    Researcher
    Biomedical Research Institute
    University Autonoma
    Spain
    jesusm.paramio@ciemat.es
    IJICR

    Research Interest: Malignant transformation, including DNA Repair mechanisms, roles of Cytoskeleton in signal transduction, Developmental processes

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    Arun Seth
    Professor
    Laboratory Medicine and Pathobiology
    University of Toronto
    Canada
    arun.seth@utoronto.ca
    IJICR

    Research Interest:

    1. Development of mouse models for understanding and treating cancer

    2. Understanding of therapies that target immune checkpoints.

    3. Tumor Biomarkers: MicroRNA signature predictive of prostate cancer recurrence and metastasis 

    4. Clinical Genomics: Application of genomics data in a clinical setting

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    Bo Jin
    Professor
    Department of Gastroenterology
    Peoples Liberation Army
    China
    bjbo.jin@gmail.com
    IJICR

    Research Interest: His interests in liver fibrosis research focuses on the use of intrahepatic administration of collagenase for reversal of liver fibrosis and this work was one of the earliest that established proof-of-principle of these potential therapeutic agents. His immunological interest lies with double-stranded RNA induced immune response and its potential application in anti-virus and/or anti-cancer immunotherapy.

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    Emmanuel Enoch Kwaku
    Professor
    School of Life Sciences
    University of Science and Technology of China
    China
    deek2083@yahoo.co.uk
    IJICR

    Research Interest: RNA interefence, Immunotherapy and Immunodiagnostics

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    Wenwen Sha
    Assistant Professor
    Immunology and Virology
    Chinese Academy of Sciences
    China
    wenwensha@gmail.com
    IJICR

    Research Interest: Immunology and Virology

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    Xia Pu
    Assistant Professor
    Cell Biology
    Liaoning medical university
    China
    nn001007@163.com
    IJICR

    Research Interest: My research direction is the biology of cancer stem cell. 

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    Rongxin Zhang
    Professor
    Laboratory of Immunology and Inflammatory Diseases
    Tianjin Medical University
    China
    rongxinz@yahoo.com
    IJICR

    Research Interest: My research interests are from basic immunology science to translational medicine in following immune associated area/diseases.

    1. Cancer Immunology and nano-medicine

    2. Obesity and Immunity

    3. Neuro-immunology (autoimmune induced central nervous system inflammation)

    4. Immunity to Infectious Diseases and Vaccines


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    Aneta Rogalska
    Professor
    Department of Thermobiology
    University of Lodz
    Poland
    zychan@biol.uni.lodz.pl
    IJICR

    Research Interest: Tumor types: ovarian, breast, lung, liver

    2. reactive oxygen and carcinogenesis

    3. signal transduction

    4. control of cell cycle progression

    6. drug resistance in vitro

    8. tubulin-targeted agents and alkylating agents

    9. mechanism of drug action/new molecular targets/therapeutics

    a) molecular mechanisms of epothilones, taxanes and anthracyclines activity in cancer and normal cells

    b) pharmaceutical agents (metformin, gliclazide, sitagliptin) used for prevention of

      diabetes complications

    10. drug discovery technologies/combination chemotherapy

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    Pawel Krawczyk
    Professor
    Department of Pneumonology
    Medical University of Lublin
    Poland
    krapa@poczta.onet.pl
    IJICR

    Research Interest: Focused on molecularly targeted therapy and genetic abnormalities in cancer (mostly in lung cancer), immunooncology, immunology and genetic of obstructive sleep apnea, asthma, COPD and sarcoidosis

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    D Sugapriya
    Assistant Professor
    Department of Medical Lab Sciences
    Prince Sattam Bin Abdullaziz University
    Saudi Arabia
    sughaphd@gmail.com
    IJICR

    Research Interest: Immunophenotyping, Immunocytochemistry, Multilineag differentiation, RNA isolation, RT- PCR, Cancer cell line, Immunocytochemistry, Real-Time PCR, Western blot, Transport mechanism by liquid santillation Counter, Induction of leukemia in experimental animal, Biochemical enzymatic analysis, TEM analysis, Histopathology, RT-PCR, apoptosis analysis, Western blot, MTT assay, Measurement of intracellular ROS, Analysis of mitochondrial membrane potential, Intracellular calcium levels, Quantification of endogenous GSH, DNA fragmentation, Column Chromatography, Antibiotic sensitivity assay, Extract preparation, Antibiotic sensitivity assay

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    Constantinos Giaginis
    Assistant Professor
    Department of Food Science & Nutrition
    University of Aegean
    Greece
    cgiaginis@yahoo.gr
    IJICR

    Research Interest: Research areas of human physiology and pathophysiology. His research focuses on the clinical evaluation of new biomarkers and molecular mediators in several pathophysiological disease states, such as diabetes, atherosclerosis and cancer. His research interest also includes the development of quantitative structure-activity relationships (QSARs) and quantitative structure-property relationships (QSPRs) in the area of toxicology and pharmacology. Furthermore, his research interest lies in the assessment of physicochemical properties, such as lipophilicity, solubility and ionization of drugs, natural bioactive compounds and toxic chemicals in relation with their potential biological activity and toxicity endpoints, as well as their Absorption/Distribution/Metabolism/Excretion (ADME) parameters and their pharmacokinetic and toxicokinetic profiles

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    Maria Filomena Rabaca Roque Botelho
    Professor
    Faculty of Medicine
    Coimbra University
    Portugal
    mfbotelho@fmed.uc.pt
    IJICR

    Research Interest: Biophysics; Development of animal models for human diseases (cancer, cardiac ischemia); Nuclear Oncology (from molecular biology to molecular imaging); Photodynamic therapy in models in vitro and in vivo; Radiopharmacy.

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    Monica C Botelho
    Head
    Head, Department of Health Promotion and Chronicle Diseases
    University of Porto
    Portugal
    monicabotelho@hotmail.com
    IJICR

    Research Interest: Molecular carcinogenesis of schistosome associated squamous cell carcinoma of the bladder with mouse experiments as models of carcinogenesis; Effects of schistosoma-derived estrogenic molecules on cell lines and the accumulation and biodistribution of these molecules in animal models, and their possible carcinogenic effect; Schistosomiasis associated catechol-estrogens.


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    Romeo-Gabriel Mihaila
    Professor
    Faculty of Medicine of Lucian Blaga
    University of Sibiu, Romania
    Romania
    romeomihaila@yahoo.com
    IJICR

    Research Interest: Leukemia and lymphoma – clinical aspects,  Adjuvant treatments in malignant hemopathies (e.g. resveratrol, statins), Connections between malignant hemopathies and dyslipidemia or metabolic syndrome, Thrombin generation in malignant hemopathies

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    Young-Hwa Chung
    Associate Professor
    Department of Cogno-Mechatronics Engineering
    Pusan Nationl University
    South Korea
    younghc@pusan.ac.kr
    IJICR

    Research Interest: Oncogenesis by viral and cellular oncogenes and cancer treatment with virus and natural drugs. 

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    Ayman M Metwally
    Associate Professor
    Technology of Medical Laboratory Department
    Misr University for Science and Technology
    Egypt
    ayman_doctor@hotmail.com
    IJICR

    Research Interest: Cancer Biology, Epigenetics, stem cells and cancer stem cells.

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    Hamiyet Donmez-Altuntas
    Professor
    Department of Medical Biology
    Erciyes University
    Turkey
    donmezh@erciyes.edu.tr
    IJICR

    Research Interest: Molecular biology, cytogenetics, genotoxicity, micronucleus, cytome assay, mutagenicity tests, gene expression, human cancer, pituitary adenomas, obesity.

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