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International Journal of Nanomaterials, Nanotechnology and Nanomedicine  Open Access


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    Arghya Narayan Banerjee

    Arghya Narayan Banerjee
    Yeungnam University, South Korea
    Tel: +82‐10‐5717‐1975
    Fax: +82‐53‐812‐2062
    Skype: arghya1975

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    Zhongchang Wang

    Zhongchang Wang
    International Iberian Nanotechnology Laboratory (INL), Portugal
    Email: ;
    Tel: +351-253-140-112
    Fax: +351-253-140-119
    Skype: zhongchang_wang

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    Executive Editors

    Wei Min HUANG
    Associate Professor
    Mechanical and Aerospace Engineering
    Nanyang Technological University

    Dr Wei Min Huang is currently an Associate Professor (tenured) at the School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore. With over 20 years of experience on various shape memory materials (alloy, polymer, composite and hybrid), he has published over 150 papers in journals, such as Advanced Drug Delivery Reviews, Materials Today, Soft Matter, and Journal of Materials Chemistry, and has been invited to review manuscripts from over 150 international journals (including Progress in Polymer Science, Advanced Materials, Advanced functional materials, Small and biomaterials, etc), project proposals from American Chemical Society, Hong Kong Research Grants Council, etc, and book proposals from CRC. He has published two books (Thin film shape memory alloys – fundamentals and device applications, Polyurethane shape memory polymers) and is currently on the editorial board of over a dozen of international journals.

    Research interest:

    1.Shape memory materials and composites (bulk and thin film)

    2.Laser annealing and micro fabrication

    3.Thin films (characterization and materials/devices)

    4.Micro/nano mechanics, nano patterning and indentation technology

    5.Surface and optical properties of smart materials

    6.Advanced and novel materials

    7.Micro assembly and packaging, active disassembly

    8.Deploy able and bi-stable structures

    9.Materials selection

    10.Flight mechanism in inserts

    11.Micro biomedical devices

    URL of Official Website:  </xml> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0cm; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-fareast-language:EN-US;} </style> URL of Official Website:

    Skype ID:

    Grant details: Current project: Self-coloring atop polymeric materials 

    No. of Publications : 183

    1.Sun L, Huang WM, Lu HB, Lim KJ, Zhou Y, Wang TX, Gao XY, Heating-responsive shape-memory effect in thermoplastic polyurethanes with low melt-flow index, Macromolecular Chemistry and Physics, Vol. 215, 2014, 2430-2436
    2.Zhang JL, Huang WM, Lu HB, Sun L, Thermo-/chemo-responsive shape memory/change effect in a hydrogel and its composites, Materials and Design, Vol. 53, 2014, 1077-1088
    3.Sun L, Huang WM, Wang CC, Ding Z, Zhao Y, Tang C, Gao XY, Polymeric shape memory materials and actuators, Liquid Crystals, Vol. 41, 2014, No. 3, 277-289
    4.Sun L, Huang WM, Lu HB, Wang CC, Tang C, Zhang JL, Shape memory technology for active assembly/disassembly: fundamentals, techniques and example applications, Assembly Automation, Vol. 34, No.1, 2014, 78-93
    5.Wu XL, Huang WM, Ding Z, Tan HX, Yang WG, Sun KY, Characterization of the thermo-responsive shape memory effect in polyether ether ketone (PEEK), Journal of Applied Polymer Science, Vol. 131, 2014, 39844
    6.Lu H, Liang F, Gou J, Huang WM, Leng J, Synergistic effect of self-assembled carbon nanopaper and multi-layered interface on shape memory nanocomposite for high speed electrical actuation, Journal of Applied Physics, Vol. 115, 2014, 064907
    7.Lu H, Huang WM, Leng J, Functionally graded and self-assembled carbon nanofiber and boron nitride in nanopaper for electrical actuation of shape memory nanocomposites, Composites Part B: Engineering, Vol. 62, 2014, 1-4
    8.Huang WM, Lu HB, Zhao Y, Ding Z, Wang CC, Zhang JL, Sun L, Fu J, Gao XY, Instability/collapse of polymeric materials and their structures in stimulus-induced shape/surface morphology switching, Materials and Design, Vol. 59, 2014, 174-192
    9.Lu H, Huang WM, Wu XL, Ge YC, Zhang F, Zhao Y, Geng JF, Heating/ethanol-response of poly methyl methacrylate (PMMA) with gradient pre-deformation and potential applications in temperature sensor and anti-counterfeit, Smart Materials and Structures, Vol. 23, 2014, 067002
    10.Lu H, Yao Y, Huang WM, Leng J, Hui D. Significantly improving infrared light-induced shape recovery behavior of shape memory polymeric nanocomposite via a synergistic effect of carbon nanotube and boron nitride, Composites: Part B, C62, 2014, 256-261
    11.Zhang JL, Huang WM, Gao G, Fu J, Zhou Y, Salvekar AV, Venkatraman SS, Wong YS, Tay KH, Birch WR, Shape memory/change effect in a double network nanocomposite tough hydrogel, European Polymer Journal, 58, 2014, 41-51
    12.Yang WG, Lu H, Huang WM, Qi HJ, Wu XL, Sun KY, Advanced shape memory technology to reshape  product design, manufacturing and recycling, Polymers, 6, 2014, 2287-2308
    13.Huang WM, Zhao Y, Zhang JL, Lu HB, Chemo-responsive shape memory/change effect in polymeric materials based on transport phenomena, Journal of Fluid Flow, Heat and Mass Transfer, 1, 2014, 16-22
    14.Huang WM, Song CL, Fu YQ, Wang CC, Zhao Y, Purnawali H, Lu HB, Tang C, Ding Z. Zhang JL, Shaping tissue with shape memory materials, Advanced Drug Delivery Reviews, Vol. 65, 2013, 515-535
    15.Cui HP, Song CL, Huang WM, Wang CC, Zhao Y, Rubber-like electrically conductive polymeric materials with shape memory, Smart Materials and Structures, Vol. 22, 2013, 055024
    16.Zhao Y, Wang CC, Huang WM, Purnawali H, Ethanol induced shape recovery and swelling in poly(methyl methacrylate) and applications in fabrication of microlens array, Advances in Science and Technology, Vol. 77, 2013, 354-358 
    17.Tang C, Huang WM, Wang CC, From dual-shape/temperature memory effect to triple-shape memory effect in NiTi shape memory alloys, Advances in Science and Technology, Vol. 78, 2013, 1-6 
    18.Chen YH, Skote M, Zhao Y, Huang WM, Stiffness evaluation of the leading edge of the dragonfly wing via laser vibrometer, Material Letters, Vol. 97, 2013, 166-168
    19.Lu HB, Huang WM, Yao YT, Review of chemo-responsive shape change/memory polymers, Pigment & Resin Technology, Vol. 4, No. 4, 2013, 237-246
    20.Lu H, Huang WM, Synergistic effect of self-assembled carboxylic acid-functionalized carbon nanotubes and carbon fiber for improved electro-activated polymeric shape-memory nanocomposite, Applied Physics Letters, Vol. 102, 2013, 231910
    21.Wu XL, Huang WM, Tan HX, Characterization of shape recovery via creeping and shape memory effect in ether-vinyl acetate copolymer (EVA), Journal of Polymer Research, Vol. 20, 2013, 150
    22.Chen YH, Skote M, Zhao Y, Huang WM, Dragonfly (sympetrum flaveolum) flight: kinematic and measurement and modelling, Journal of Fluids and Structures, Vol. 40, 2013, 115-126
    23.Lu H, Huang WM, Liang, F, Yu K, Nanoscale design of nano-sized particles in shape-memory polymer nanocomposites driven by electricity, Materials, Vol. 6, 3742-3754
    24.Lu H, Huang WM, On the origin of the Vogel–Fulcher–Tammann law in the thermo-responsive shape memory effect of amorphous polymers, Smart materials and Structures, Vol. 22, 2013, 105021
    25.Lu H and Huang WM, A phenomenological model for the chemo-responsive shape memory effect in amorphous polymers undergoing viscoelastic transition, Smart Materials and Structures, Vol. 22, 2013, 115019
    26.Lu H, Yin W, Huang WM, Leng JS, Self-assembled carboxylic acid-functionalized carbon nanotubes grafting onto carbon fiber for significantly improving electrical actuation of shape memory polymers, RSC Advances, Vol. 3, Issue 44, 2013, p 21484-21488
    27.Sun L and Huang WM, Reply to “Comment on ‘Mechanisms of the multi-shape memory effect and temperature memory effect in shape memory polymers’" by H. Lu, Soft Matter, 2013, 9, DOI:10.1039/C3SM51720A”, Soft Matter, Vol. 9, 2013, 11159
    28.Wu XL, Huang WM, Seow ZG, Chin WS, Yang WG, Sun KY, Two-step shape recovery in heating-responsive shape memory polytetrafluoroethylene (PTFE) and its thermally assisted self-healing, Smart Materials and Structures, Vol. 22, 2013, 125023
    29.Wu X, Huang WM, Zhao Y, Ding Z, Tang C, Zhang J, Mechanisms of the shape memory effect in polymeric materials, Polymers, Vol. 5, 2013, 1169-1202
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    Hermis Iatrou

    Prof Hermis Iatrou has received his PhD  in University of Athens, Chemistry Department on December 1993. Currently, he is working as a Professor and Director of the Industrial Chemistry Lab in the University of Athens. He has successfully completed his Administrative responsibilities as Director of Section II of the Chemistry Department of the University of Athens .He is serving as an editorial member of several reputed journals like Journal of Materials, Hindawi. He has authored 120 research articles/books. He is a member of Hellenic Polymer Society as well as the Hellenic Society of Applications of Nanomedicine.

    Research Interest:

    A. Polymer Synthesis

    Β. Polymer Characterization and their Properties.

    C. Solid State Properties of Polymers.

    URL of Official Website:

    Skype ID: hermis.iatrou

    Grant/ Funding Details: Participated as IP or member in more than 25 national and international projects.

    No. of Publications: 117

    1.Η. Iatrou and Ν. Hadjichristidis “Synthesis of a Model 3-Miktoarm Star Terpolymer.”
    Macromolecules, 1992, 25, 4649.

    2.Η. Iatrou and Ν. Hadjichristidis “Synthesis and Characterization of Model 4-Miktoarm Star Co- and Quaterpolymers.” Macromolecules, 1993, 26, 2479.

    3.J. Roovers; Zhou Lin Lin; P. Toporowski; van der Zwan, Mark; H. Iatrou; and N. Hadjichristidis “Regular Star Polymers with 64 and 128 arms. Models for polymeric Micelles.” Macromolecules, 1993, 26, 4324.

    4.N. Hadjichristidis; H. Iatrou; S. Behal; J. Chludzinski; M. Disko; R. Garner; S. Liang; D. Lohse; S.Milner
    “Morphology and Miscibility of Miktoarm Styrene-Diene Copolymers and Terpolymers.” Macromolecules, 1993, 26, 5812.

    5.G. Floudas; N. Hadjichristidis; H. Iatrou; T. Pakula; E. Fisher “Microphase Separation in Model 3-Miktoarm Star Copol (Simple Graft) and Terpolymers. 1. Statics and Kinetics” Macromolecules, 1994, 27, 7735.

    6.H. Iatrou ; A. Avgeropoulos; N. Hadjichristidis “Synthesis of Model Super H-Shaped Block Copolymers.” Macromolecules, 1994, 27, 6232.

    7.H. Iatrou; E. Siakali; N. Hadjichristidis; J. Roovers ; J. Mays “Hydrodynamic Properties of Model 3-Miktoarm Star Copolymers.” J. Polym. Sci. Part B: Polym. Phys. 1995, 33, 1925.

    8.N. Hadjichristidis; H. Iatrou; Y. Tselikas; V. Efstratiadis Miktoarm Star Polymers.” Chim. Chron., New Series, 1995, 24, 189.

    9.H. Iatrou; L. Willner; N. Hadjichristidis; A. Halperin; D. Richter  “Aggregation Phenomena of Model Super-H-Shaped Block Copolymers. Influence of the Architecture.” Macromolecules, 1996, 29, 581.

    10.G. Floudas; N. Hadjichristidis; H. Iatrou; T. Pakula “Microphase Separation in Model 3-Miktoarm Star Co- and Terpolymers. 2. Dynamics.” Macromolecules, 1996, 29, 3139.

    11.Y. Tselikas;  H. Iatrou; N. Hadjichristidis; S. Liang; K. Mohanty; D. Lohse “Morphology of Miktoarm Star Block Copolymers of Styrene and Isoprene.” J. Chem. Phys., 1996,105, 2456.

    12.N. Hadjichristidis; Y. Tselikas; H. Iatrou; V. Efstratiadis;  A. Avgeropoulos “Model Nonlinear Block Copolymers: Synthesis, Characterization, Morphology.” J. Macromol. Sci. Pure Appl. Chem. 1996, A33, 1447.

    13.N. Hadjichristidis; H. Iatrou; Y. Tselikas; J. Mays “Miktoarm Star Polymers.” Polymeric Materials Encyclopedia, Volume 6, 4398-4406, CRC Press, Boca Raton, N.Y., London, Tokyo.

    14.H. Iatrou; J. Mays, and N. Hadjicrhistidis “Regular comb polystyrenes and graft polyisoprene/polystyrene copolymers with double branches (Centipedes). Quality of (1,3-henylene)bis(3-methyl-1-phenylpentylidene) dilithium initiator in the presence of polar additives” Macromolecules, 1998, 31, 6697.

    15.G. Floudas; N. Hadjicrhistidis; H. Iatrou; A. Avgeropoulos; T. Pakula “Microphase separation in Super-H-shaped block copolymer colloids” Macromolecules, 1998, 31, 6943.

    16.Ν. Hadjichristidis; S.Pispas; M. Pitsikalis; H. Iatrou and C. Vlahos “Asymmetric star polymers: Synthesis and properties” Advances in Polymer Science, 1999, 142, 71.

    17.N. Chan; J. Hoffman; V. Lee; H. Iatrou; A. Avgeropoulos; N. Hadjichristidis; R. Miller and E. Thomas
    “Ordered bicontinuous nanoporous and nanorelief ceramic films from self assembling polymer precursors”
    Science, 1999, 286, 1716.

    18.F. Beyer; S. Gido; C. Buschl; H. Iatrou; D. Uhrig; J. Mays; M. Chang; B. Garetz; N. Balsara; N. Tan; and N. Hadjichristidis “Graft copolymers with regularly spaced, tetrafunctional branch points: morphology and grain structure” Macromolecules, 2000, 33, 2039.

    19.N. Hadjichristidis; M. Xenidou; H. Iatrou; M. Pitsikalis; Y. Poulos; A. Avgeropoulos; S. Sioula; S. Paraskeva; G. Velis; D. Lohse; D. Schultz; L. Fetters; P. Wright; R. Mendelson; C. Franco; T. Sun and C. Ruff “Well-defined, model long chain branched polyethylene. 1. Synthesis and characterization”
    Macromolecules, 2000, 33, 2424.

    20.V. Bellas; H. Iatrou and N. Hadjichristidis “Controlled anionic polymerization of hexamethylcyclotrisiloxane model linear and miktoarm star Co- and terpolymers of Dimehylsiloxane with Styrene and isoprene” Macromolecules, 2000, 33, 6993.

    21.Y. Nakamura; Y. Wan; J. Mays; H. Iatrou and N. Hadjichristidis “Radius of gyration of polystyrene combs and centipedes in solution” Macromolecules, 2000, 33, 8328.

    22.Ν. Hadjichristidis; H. Iatrou; S.Pispas and M. Pitsikalis “Αnionic polymerization: High vacuum techniques” J. Polym Sci A: Polym Chem, 2000, 38, 3211.

    23.G. Wise; M. Denn; A. Bell; J. Mays, K. Hong, H. Iatrou “Surface Mobility and Slip of Polybutadiene Melts in Shear Flow” J. Rheol., 2000, 44(3), 549.

    24.G. Floudas; B. Vazaiou; F. Schipper; R. Ulrich; U. Wiesner; H.Iatrou and N. Hadjichristidis
    “Poly(ethylene oxide-b-isoprene) Diblock Copolymer Phase Diagram” Macromolecules, 2001, 34, 2947.

    25.N. Hadjichristidis; M. Pitsikalis; S. Pispas and H. Iatrou, “Polymers with Complex Architectures by Living Anionic Polymerization” Chemical Reviews, 2001, 101, 3747.

    26.H. Pasch; E. Esser; C. Kloninger; H. Iatrou and N. Hadjichristidis “Chromatographic Investigations of Macromolecules in the Critical range of Liquid chromatography. XIV. Analysis of miktoarm Star Polymers”
    Macromolecular Chemistry and Physics, 2001, 202, 1424.

    27.V. Bellas; H. Iatrou; Ε. Pitsinos and N. Hadjichristidis “Heterofunctional Linking Agents for the Synthesis of Well-Defined Block Copolymers of Dimethylsiloxane and t-Butyl Methacrylate or 2-Vinyl Pyridine” Macromolecules, 2001, 34, 5376.

    28.R. Weidisch; S. Gido; D. Uhrig; H. Iatrou; J. Mays and N. Hadjichristidis “Tetrafunctional Multigraft Copolymers as Novel thermoplastic   Elastomers” Macromolecules, 2001, 34, 6333.

    29.K Takahashi, H. Hasegawa, T. Hashimoto, V. Bellas, H. Iatrou, and N. Hadjichristidis “Four-Phase Triple Coaxial Cylindrical Microdomain Morphology in a Linear Tetrablock Quaterpolymer of Styrene, Isoprene, Dimethylsiloxane, and 2-Vinylpyridine” Macromolecules, 2002, 35, 4859.

    30.Sophia Houli, Hermis Iatrou, NikosHadjichristidis, and Dimitris Vlassopoulos “Synthesis and Viscoelastic Properties of Model Dumbbell Copolymers Consisting of a Polystyrene Connector and Two32-Arm Star Polybutadienes” Macromolecules 2002, 35, 6592.

    31.M. Stogiou; C. Kapetanaki and H. Iatrou “Examination of the Universality of the Calibration Curve of Size Exclusion Chromatography by using Polymers Having Complex Macromolecular Architectures.”
    International Journal of Polymer Analysis and Characterization, 2002, 7, 273.

    32.V. Bellas, E. Tegou, I. Raptis, P. Argitis, H. Iatrou, N. Hadjichristidis, E. Sarantopoulou, A. Cefalas,
    “Evaluation of Siloxane and Polyhedral Silsesquioxane Copolymers for 157 nm Lithography” J. Vac. Sci. Technol. 2002, B 20 (6), 2902.

    33.P. Fragouli, H. Iatrou, N. Hadjichristidis,“Synthesis and Characterization of Linear Diblock and Triblock Copolymers of 2-Vinyl Pyridine and Ethylene Oxide” Polymer 2002, 43, 7141.

    34.Ν. Hadjichristidis, S.Pispas, H. Iatrou, M. Pitsikalis,“Linking chemistry and anionic polymerization”
    Current Organic Chemistry 2002, 6, 155.

    35.Ν. Hadjichristidis, S.Pispas, M. Pitsikalis, H. Iatrou, D. J. Lohse “Graft copolymers”
    Encyclopedia of Polymer Science and Technology, Wiley, 2002.

    36.H. Iatrou, N. Hadjichristidis, G. Meier, H. Frielinghaus, and M. Monkenbusch “Synthesis and Characterization of Model Cyclic Block Copolymers of Styrene and Butadiene. Comparison of the Aggregation Phenomena in Selective Solvents with Linear Diblock and Triblock Analogues”
    Macromolecules 2002, 35, 5426.
    37.Y. Zhu, S. Gido, H. Iatrou, N. Hadjichristidis, J. Mays “Microphase Separation of Cyclic Block Copolymers of Styrene and Butadiene and of their Corresponding Linear Triblock Copolymers”
     Macromolecules 2003; 36; 148.

    38.K. Yamauchi, K. Takahashi, H. Hasegawa, H. Iatrou, N. Hadjichristidis, T. Kaneko, Y. Nishikawa, H. Jinnai, T. Matsui, H. Nishioka, M. Shimizu, H. Furukawa “Microdomain Morphology in an ABC 3-Miktoarm Star Terpolymer: A study by Energy-Filtering TEM and 3D Electron Tomography” Macromolecules 2003, 36, 6962.

    39.Y. Zhu, S. Gido, M. Moschakou, H. Iatrou, N. Hadjichristidis, S. Park, T. Chang “Effect of junction point functionality on the lamellar spacing of symmetric (PS)n(PI)n Miktoarm star block copolymers”
    Macromolecules 2003, 36, 5719.

    40.P. Fragouli, H. Iatrou, N. Hadjichristidis “Synthesis and characterization of linear tetrablock quarterpolymers of styrene, isoprene, dimethylsiloxane and 2-vinylpyridine” J. Polym. Sci. Part A: Polym. Chem. 2003, 42, 514.

    41.Nikos Hadjichristidis,  Marinos Pitsikalis, Hermis Iatrou, Stergios Pispas “The Strength of the Macromonomer Strategy for Complex Macromolecular Architecture: Molecular Characterization, Properties and Applications of Polymacromonomers” Macromolecular Rapid Communications 2003, 24, 979.

    42.Thrasyvoulos Aliferis, Hermis Iatrou, and Nikos Hadjichristidis “Living Polypeptides”
    Biomacromolecules 2004, 5, 1653.

    43.J. Mays, D. Uhrig, S. Gido, Y. Zhu, R. Weidisch, H. Iatrou, N. Hadjichristidis, K. Hong, F. Beyer, R. Lach, M. Buschnakowski “Synthesis and Structure-Property Relationship for Regular Multigraft Copolymers” Macromol. Symposia 2004, 215, 111.

    44.X. Hu, Y. Zhu, S. Gido, T. Russell, H. Iatrou, N. Hadjichristidis, F. Abuzain, and B. Garetz “The effect of molecular architecture on the grain growth kinetics of AnBn star block copolymers” Faraday Discuss., 2005, 128, 103.

    45.H. Iatrou, M. Pitsikalis, N. Hadjichristidis, “Hyperbranched Architectures. Synthesis-Characterization-Properties” NATO Science Series II: Mathematics, Physics and Chemistry (2004), 175 (Modification and Blending of Synthetic and Natural Macromolecules, 73-89, 2004, Kluwer Academic Publishers).

    46.M. Vamvakaki, L. Papoutsakis, V. Katsamanis, T. Afchoudia, P. Fragouli, H. Iatrou, N. Hadjichristidis, S. Armes, S. Sidorov, D. Zhirov, V. Zhirov, M. Kostylev, L. Bronstein and S. Anastasiadis “Micellization in pH-sensitive amphiphilic block copolymers in aqueous media and the formation of metal nanoparticles”
    Faraday Discussions, 2005, 128, 129.

    47.N. Hadjichristidis,  H. Iatrou, M. Pitsikalis, “Macromolecular Engineering”  McGraw Hill, Yearbook of Science and Technology 2005, 181.

    48.K. Terao, B. Farmer, Y. Nakamura, H. Iatrou, K. Hong, J. Mays “Radius of Gyration of Polystyrene Combs and Centipedes in a Θ Solvent” Macromolecules 2005, 38, 1447.

    49.N. Hadjichristidis, M. Pitsikalis and H. Iatrou “Synthesis of block copolymers”Advances in Polymer Science 2005, 189, 1.

    50.N. Hadjichristidis, H. Iatrou, M. Pitsikalis, S. Pispas, A. Avgeropoulos “Linear and Non-Linear Multiblock Terpolymers. Synthesis, Self-Assembly in Selective Solvents and in Bulk” Progress in Polymer Science 2005, 30, 725. and More....

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    Editorial Board

    Naveena Yanamala
    Associate Service Fellow
    Health Effects Laboratory Division

    Research Interest: Nanotoxicology, Pulmomary Toxicity, Computational Toxicity Models, Molecular Modeling and Dynamics Simulations, Biomarkers.

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    Chunya Li
    South-Central University for Nationalities

    Research Interest: Nanomaterials; Ionic liquid; Electrochemistry; Biosensor.

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    Xianbiao Wang
    Schoool of Materials and Chemical Engineering
    Anhui Jianzhu University

    Research Interest: Micro/nanostructured Materials for Pollutants Adsorption and Detection; Electrospinning Polymer Fibers; Carbonaceous Catalysts for Fuel Cells.

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    Kityk IV
    Electrical Engineering Deprtment
    Czestochowa Technical University
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    Soo-Young Park
    Department of Polymer Science and Engineering
    Kyungpook National University
    South Korea

    Research Interest: Nanocomposite, Liquid crystal, sensor, synchrotron, X-ray diffraction, polymer crystal structure

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    Luis F Silva Oliveira
    La Salle University Center
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    Shyh-Dar Li
    Associate Professor
    Pharmaceutical Sciences
    University of British Columbia

    Research Interest: Developing innovative drug delivery technologies to enhance cancer therapy with a particular interest in lipid and polymer based nanoparticles

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    Tapas Sen
    Centre for Materials Science
    University of Central Lancashire

    Research Interest: Nano-biomaterials, Nano-biosensors, Drug delivery, Tissue engineering, Bio-separations, Water purification and Heterogeneous catalysis.

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    Stella Girousi
    Associate Professor
    Aristotle University of Thessaloniki

    Research Interest: Electroanalysis and electrochemical biosensors.

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    Rasha Abd Ellattef Ahmed
    Assistant Professor
    Chemistry Department
    Taif University
    Saudi Arabia

    Research Interest: Modification and application of polymers using different nanomaterials, especially conducting polymer-based nanomaterials, which including nanoparticles, nanocomposites, nanoporous materials and nanostructures. Taking advantage of the special properties of conducting polymers and nanomaterials, I have been working on the development of electrochemical sensors for the determination of narcotic and neurotransmitter drugs. My currentresearch interest is focused on material science, especially using Natural resources to overcome microbial infections, deterioration of metals used in medical implant.

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    Neng-Hui Zhang
    Department of Mechanics
    Shanghai University

    Research Interest: Nanomechanics in biochip systems; Viscoelasticity; Nonlinear Dynamics.

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    Kwang-Hee Lim
    Department of Biomedical Science
    CHA University

    Kwang-Hyun Baek is a full professor of Department of Biomedical Science and a director of Cell & Gene Therapy Research Institute at CHA University in Korea. He received his Ph.D. from the department of Zoology and Genetics at Iowa State University in US in 1995 and worked as a postdoctoral research fellow in the division of Genetics at Brigham and Women’s Hospital and in the department of Pediatric Oncology at Dana-Farber Cancer Institute, Harvard Medical School. He has been serving as an editorial board member, a regional editor, and an editor-in-chief of many international journals. Current research and clinical interests are in the molecular genetics of ubiquitination and deubiquitination systems relevant to various cancers and stem cell proliferation/differentiation. He first coined terms ubiquitomics and deubiquitomics in the field of the ubiquitin-proteasome system. In addition, he is interested in genomics and proteomics during cancer cell proliferation and apoptosis.

    Research Interest: Nano-Bio, Drug delivery system, Nanoparticle, Gelatin, Chitosan, Fucoidan, Agar, Anticancer drug, Nanoprecipitation, Polyelectrolyte complex, Wound dressing, Wound healin.

    Grant Details:

    1) Korean Ministry of Health & Welfare: The prevention of high-risk pregnancy: Development of biomarkers for recurrent pregnancy loss using multi-omics. April 2018 ~ December 2020 ($350,000).
    2) Korea Research Foundation: Investigation of cellular mechanisms for DNA repair mediated by deubiquitinating enzymes and identification of their small molecules. June 2016 ~ May 2019 ($300,000).
    3) Korea Ministry of Environment: Screening and pathophysiology mechanisms of environmental risk factors for premature ovarian failure. May 2016 ~ December 2019 ($600,000).
    4) Korea Ministry of Science and Technology: BK21 Plus Program. September 2013 ~ August 2020 ($200,000 every year)"
    Publication List:

    1. Hiriyanna, K. T., Baedke, D., Baek, K.-H., Forney, B. A., Kordiyak, G., and T. S. Ingebritsen. (1994). Thiophosphorylated substrate analogs are potent active site-directed inhibitors of protein-tyrosine phosphatases. Anal. Biochem. 223: 51-58.

    *2. Baek, K.-H., and L. Ambrosio. (1994). An efficient method for microinjection of mRNA into Drosophila embryos. BioTechniques 17: 1024-1026. (Corresponding author)

    3. Baek, K.-H., Fabian, J., Sprenger, F., Morrison, D., and L. Ambrosio. (1996). The activity of D-raf in Torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev. Biol. 175: 191-204.

    *4. Baek, K.-H., and W. P. Hanratty. (1996). The characterization of temperature-sensitive lethal (2) giant larvae alleles in Drosophila melanogaster. Drosophila Infor. Serv. 77: 90-92. (Corresponding author)

    5. Johansen, K. M., Johansen, J., Baek, K.-H., and Y. Jin. (1996). Remodeling of nuclear architecture during the cell cycle in Drosophila embryos. J. Cell. Biochem. 63: 268-279.

    6. Radke, K., Baek, K.-H., and L. Ambrosio. (1997). Characterization of maternal and zygotic D-raf proteins: dominant negative effects on Torso signal transduction. Genetics 145: 163-171.

    *7. Baek, K.-H., and W. P. Hanratty. (1997). The l(2)gl, a recessive oncogene, is required during embryonic and post-embryonic development in Drosophila. Cancer Lett. 111: 233-238. (Corresponding author)

    8. Michelson, A. M., Gisselbrecht, S., Zhou, Y., Baek, K.-H., and E. M. Buff. (1998). Dual functions of the heartless fibroblast growth factor receptor in development of the Drosophila embryonic development. Dev. Genetics 22: 212-229.

    *9. Baek, K.-H. (1999). The first oncogene in Drosophila melanogaster. Mut. Res. 436: 131-136. (Corresponding author)

    *10. Baek, K.-H. (1999). The application of temperature-sensitive mutations in Drosophila. Arch. Pharm. Res. 22: 229-231. (Corresponding author)

    11. Jaster, R., Baek, K.-H., and A. D'Andrea (1999). Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the murine DUB-1 gene. Biochim. Biophys. Acta 1446: 308-316.

    *12. Baek, K.-H., and K. Y. Lee. (1999). Signal transduction pathway for anterior-posterior development in Drosophila. J. Biomed. Sci. 6: 314-319. (Corresponding author)

    *13. Baek K.-H., Kim M. K., Lee, K. Y., and K. Y. Cha (2000). Raf serine/threonine kinase is required for early embryogenesis in Drosophila. Kor. J. Genetics 22: 63-70. (Corresponding author)

    *14. Lee, J.-H., Kim, Y.-S., Kang, W.-P., and K.-H. Baek (2001). Temporal enzymatic activity of lymphocyte-specific deubiquitinating enzymes. Kor. J. Genetics 23: 3-6. (Corresponding author)

    *15. Baek, K.-H. (2001). Heartless, a fibroblast growth factor receptor, is  required for embryonic muscle development in Drosophila. Kor. J. Genetics 23: 151-156. (Corresponding author)

    *16. Lee, J.-H., Kim, M., Kim, Y.-S., and K.-H. Baek (2001). Critical regions for deubiquitinating activity of DUB-2 expressed in T lymphocytes. Am. J. Hematol. 67: 270-272. (Corresponding author)

    17. Baek, K.-H., Mondoux, M. A. Jaster, R., Fire-Levin, E., and A. D'Andrea (2001). DUB-2A, a new subfamily member of deubiquitinating enzymes. Blood 98: 636-642.

    *18. Choi, B. C., Kim, J. W., Lee, J., Yoo, K. J., Byun, H. K., Hwang, C. S., Moon, I. K., Kim, S. N., and K.-H. Baek (2001). The effect of exocelomic fluid in the first trimester pregnancy on trophoblast cell proliferation in vitro. Kor. J. Obs. Gyn. 44: 1678-1684. (Corresponding author)

    *19. Baek, K.-H., Kim., Y.-S., Jung, S., Lee, K.-Y., Choi, H.-K., and K.-S, Kim. (2002). Molecular cloning and characterization of bovine bgl-1, a novel family member of WD-40 repeat containing lethal giant lerval tumor suppressor genes. Int. J. Oncol. 20: 739-744.  (Corresponding author)

    *20. Baek, K.-H., Park, K.-H., Kim, Y.-S., Kim, M.-S., and H.-K. Choi. (2002). Molecular cloning and complete cDNA sequence of UBH1 in mouse testis. DNA Seq. 13: 145-148. (Corresponding author)

    *21. Kim, Y.-S., Baek, K.-H., Lee, K. Y., Jung, S., Chung, H.-M., Lee, K.-A., and K. Y. Cha. (2002). The rgl-1 is a legitimate homologue of lethal giant larvae recessive oncogene in rat. Int. J. Oncol. 20: 1219-1225.  (Corresponding author)

    *22. Baek, K.-H., Choi, B. C., Lee, J.-H., Choi, H.-K. Lee, S.-H., Kim, J.-W., Hill, J. A., Chung, H.-M., Ko, J. J., and K. Y. Cha. (2002). Comparison of gene expression at the feto-maternal interface between normal and recurrent pregnancy loss patients. Repro. Fertil. Dev. 14: 235-240. (Corresponding author)

    *23. Baek, K.-H., Kim., Y.-S., Chung, H. -M., Ko, J. J. and K. Y. Cha. (2002). Conservation of the lethal giant larvae tumor suppressor gene in Bos taurus coreanae. Kor. J. Genetics, 24: 127-132. (Corresponding author)

    *24. Baek, K.-H. (2002). Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines. Am. J. Hematol. 71: 340-345. (Corresponding author)

    *25. Lim, S.-K., Kim, M.-S., Lee, S.-H., and K.-H. Baek (2002). Polymorphism of CYP17 and CYP11a for polycystic ovary syndrome in a korean population. Kor. J. Genetics, 24: 343-348. (Corresponding author)
    *26. Baek, K.-H. (2003). Conjugation and deconjugation of ubiquitin regulating the destiny of proteins. Exp. Mol. Med. 35: 1-7. (Corresponding author)

    *27. Kim, Y.-S., Chung, H. M., and Baek, K.-H. (2003). WD-40 repeat containing rat lethal giant larvae recessive oncogene, but not tomosyn, restores the salt sensitivity in Saccharomyces cerevisiae. Int. J. Oncol. 23: 229-234. (Corresponding author)

    28. Chung, K.-H., Kim, S.-H., Han, K.-Y., Sohn, Y.-D., Chang, S.-I., Baek, K.-H., Kim, D.-S., and Kang, l. (2003). Inhibitory effect of salmosin, a Korean snake venom-derived disintegrin, on integrin av-mediated proliferation of SK-Mel-2 human melanoma cells. J. Pharm. Pharmacol. 55: 1577-1582.

    *29. Choi, H.-K., Choi, B. C., Lee, S.-H., Kim, J. W. Cha, K. Y., and Baek, K.-H. (2003). The expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol. Reprod. Dev. 66: 24-31. (Corresponding author)

    *30. Kim, Y.-S., Song, J., Kim, Y.-K., Kim, I.-O., Kang, I., and Baek, K.-H. (2003). Functional and expression analyses of mgl-1, a mouse orthologue of lethal giant larvae recessive oncogene. Int. J. Oncol. 23: 1515-1519. (Corresponding author)

    *31. Shin, J.-M., Kim, J.-W., Choi, B., Lee, S.-H., and Baek, K.-H. (2003). Expression of immunosuppression-related genes in fetal chorionic villi derived from recurrent spontaneous abortion patients. Kor. J. Fertil. Steril. 30: 233-240. (Corresponding author)

    32. Lee, K.-W., Jeong, Y.-M., Lee, S.-H., Yoon, T. K., Kwak, I. P., Yoon, S. W., Choi, J. S., Kim, K. H., Han, J. S., Kim, S. D., Kim, N. K., Cha, K. Y., Baek, K.-H., and Lee, S. (2003). The study of 5,10- methylenetetrahydrofolate reductase variation (MTHFR C677T) in fertile females with polycystic ovarian syndrome (PCOS) in Korea. Kor. J. Fertil. Steril. 30: 217-222.

    *33. Lim, S.-K., Shin, J.-M., Kim, Y.-S., and Baek, K.-H. (2004). Identification and characterization of murine mHAUSP encoding a deubiquitinating enzyme that regulates the status of p53 ubiquitination. Int. J. Oncol. 24: 357-364. (Corresponding author)

    *34. Baek, K.-H., Kim, M.-S., Kim, Y.-S., Shin, J.-M., and Choi, H.-K. (2004). DUB-1A, a novel subfamily member of deubiquitinating enzyme, is polyubiquitinated and cytokine-inducible in B lymphocytes. J. Biol. Chem. 279: 2368-2376. (Corresponding author)

    35. Jeon, S. Y., Baek, K.-H., Kim, Y.-S., Kwon, H. S., Ko, S. H., Song, K. -H., Yoo, S. J., Son, H. S., Cha, B. Y., Lee, K.W., Son, H. Y., Kang, S. K., and Yoon, K. H. (2004). Differentially up-regulated genes in proliferating porcine neonatal pancreas cells caused by epidermal growth factor. J. Cell. Biochem. 91: 354-364.

    36. Burrows, J. F., McGrattan, M. J., Rascle, A., Humbert, M., Baek, K.-H., and Johnston, J. A. (2004). DUB-3, a cytokine inducible deubiquitinating enzyme that blocks proliferation. J. Biol. Chem. 279: 13993-14000.

    *37. Baek, K.-H. (2004). Structural and functional conservation of the lgl recessive oncogenes. Int. J. Oncol. 24: 1257-1262. (Corresponding author)

    *38. Baek, K.-H. (2004). Aberrant gene expression associated with recurrent pregnancy loss. Mol. Hum. Reprod. 10: 291-297. (Corresponding author)

    *39. Kim, M.-S., Yoo, K.-J., Kang, I., Chung, H.M., and Baek, K.-H. (2004). A novel cysteine protease HeLa DUB-1 responsible for cleaving the ubiquitin in human cancer cells. Int. J. Oncol. 25: 373-379. (Corresponding author)

    *40. Kim, K.-S., Kim, M.-S., Kim, S.-K., and Baek, K.-H. (2004). Murine Asb-17 expression during mouse testis development and spermatogenesis. Zygote 12: 151-156. (Corresponding author)

    *41. Baek, K.-H., Kim, Y.-S., Lee, H.-J., and Kang, I. (2004). The essential regions for deubiquitinating enzyme activity and enhancer funciton for DUB-2A expressed in T-lymphocytes. Arch. Biochem. Biophys. 430: 191-197. (Corresponding author)

    *42 Kim, Y.-K., Kim, Y.-S., Chung, H.-M., and Baek, K.-H. (2004). Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes. Oncol. Rep. 12: 1105-1108. (Corresponding author)

    *43 Lee, H.-J., Yoo, K.-J., and Baek, K.-H. (2004). Structrual characterization of mouse HAUSP, a proteolysis regulator of p53. Kor. J. Biol. Sci. 8: 205-212. (Corresponding author)

    44. Hwang, K.R., Choi, Y.M., Choi, D.S., Baek, K.-H., Jeon, H.W., Bae, K.B., Son, Y.S., Ku, S.Y., Jee, B.C., Suh, C.S., Kim, S.H., Kim, J.G., and Moon, S.Y. (2004). Effect of metformin treatment and insulin resistance in patients with polycystic ovary syndrome. Kor. J. Obs. Gyn. 47: 1949-1953.

    *45. Kim, M.-S., Kim, Y.-K., Kim, Y.-S., Seong, M., Choi, J.-K., and Baek, K.-H. (2005). Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. Biochem. Biophys. Res. Commun. 330: 797-804. (Corresponding author)

    46. Lee, J., Choi, B.C., Cho, C., Hill, J.A, Baek, K.-H., and Kim, J.W. (2005).  Trophoblast apoptosis is increased in women with evidence of Th-1 immunity. Fertil. Steril. 83: 1407-1409.

    *47. Yoo, K.-J., Lee, H.-J., Lee, H., Lee, K.-Y., Lee, S.-H., Chung, H.-M., and Baek, K.-H. (2005). Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells. Int. J. Oncol. 27: 97-104. (Corresponding author)

    *48. Kim, Y.-K., Kim, Y.-S., and Baek, K.-H. (2005). The WD-40 repeat motif of Lgl tumor suppressor proteins associated with salt tolerance and temperature sensitivity. Biochem. Biophys. Res. Commun. 331: 922-928. (Corresponding author)

    *49. Lee, E.-J., Yoo, K.-J., Kim, S.-J., Lee, S.-H., Choi, D.-H., Cha, K.-.Y., Choi, D.-S., and Baek, K.-H. (2005). Relationship between the C/T single nucleotide polymorphism in exon 17 of the insulin receptor gene and polycystic ovary syndrome. J. Biol. Sci. 5: 832-836. (Corresponding author)

    50. Kang, I.-C., Min, B., Ahn, E., Son, H., and Baek, K.-H. (2005). Expression of soluble recombinant integrin alpha V and beta 3 from SF21 cells with baculovirus expression vector for targeted screening of integrin antagonists. Kor. J. Genetics 27: 211-217.

    *51. Lee, H.-J., Kim, M.-S., Kim, Y.-K., Oh, Y.-K., and Baek, K.-H. (2005). HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated,  polyneddylated, and dimerized. FEBS Lett. 579: 4867-4872. (Corresponding author)

    *52. Seong, M., Kim, M.-S., Kim, Y.-S., Lee, S.-H., Lee, H.-J., Cha, K.-Y., and Baek, K.-H. (2005). HIDE, a testis specific deubiquitinating enzyme, interacts with HSP90. Kor. J. Fertil. Steril. 32: 231-242. (Corresponding author)

    *53. Lee, M.-Y., and Baek, K.-H. (2005). Regulation of insulin signaling through protein degradation. Kor. J. Endocrinol. 20: 434-440. (Corresponding author) 

    *54. Baek, K.-H. Lee, H.-J., Kim, M.-S., Kim, Y.-S., Lee, E.-J., and Lee, M.-Y. (2006). Molecular cloning of rHAUSP encoding a deubiquitinating enzyme in a rat testis. Oncol. Rep. 15: 173-177. (Corresponding author)

    *55. Lee, H.-J., Kim, M.-S., Shin, J.-M., Park, T.-J., Chung, H.-M., and Baek, K.-H. (2006). The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Mech. Dev. (Gene Exp. Patterns) 6: 277-284. (Corresponding author)

    56. Gu, Y.-M., Jin, Y.-H., Choi, J.-K., Baek, K.-H., Yeo, C.-Y., and Lee, K.-Y. (2006). Protein kinase A phosphorylates and regulates dimerization of 14-3-3 zeta. FEBS Lett. 580: 305-310.

    *57. Baek, K.-H. (2006). Cytokine-regulated degradation by the ubiquitination system. Curr. Protein Pept. Sci. 7: 171-177. (Corresponding author)

    *58. Lee, E.-J., Yoo, K.-J., Kim, S.-J., Lee, S.-H., Cha, K.Y., and Baek, K.-H. (2006). Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertil. Steril. 86: 380-385. (Corresponding author)

    *59. Cheon, K.-W., and Baek, K.-H.  (2006). HAUSP as a therapeutic target for hematopoietic tumors. Int. J. Oncol. 28: 1209-1215. (Corresponding author)

    *60. Kim, Y.-S., Kim, M.-S., Lee, S.-H., Choi, B.-C., Lim, J.-M., Cha, K.-Y., and Baek, K.-H. (2006). Proteomic analysis of recurrent spontaneous abortion: identification of an inadequately expressed set of proteins in human follicular fluid. Proteomics, 6: 3445-3454. (Corresponding author)

    *61. Kim, Y.-S., Kim, Y.-K., Park, J.-M., Han, I.-S., Ajjappala, B.S., Kang, I., and Baek, K.-H.  (2006). Disruption of protein-protein interaction for Mgl-1 oncoprotein. Oncol. Rep. 16: 795-800. (Corresponding author)

    62. Kim, S.-J., Lee, S.-Y., Lee, C., Kim, I., An, H.-J., Kim, J.-Y., Baek, K.-H., Kim, E.-J., Kim J.-M., Lee, J.-B., Lee, J.-W., Jung, W.-W., Chun, T., and Oh, Y.-K. (2006). Differential expression profiling of genes in a complete hydatidiform mole using cDNA microarray analysis. Gynecol. Oncol. 103: 654-660.

    *63. Shin, J.-M., Yoo, K.-J., Kim, M.-S., Kim, D., and Baek, K.-H.  (2006). Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. BMC Genomics 7: 292. (Corresponding author)

    64. Park, J.-E, Jang, M.-H., Cho, S.-W., Kim, Y.-S., Won, H.-J., Cho, J.-H., Baek, K.-H., and Lee, S.-H. (2006). Mitochondrial DNA copy number in the patients of Korean polycystic ovary syndrome (PCOS). Kor. J. Fertil. Steil. 33: 245-251.

    *65. Kim, Y.-K., Kim, Y.-S., Yoo, K.-J., Lee, H.-J., Lee, D.-R., Yeo, C.Y., and Baek, K.-H.  (2007). The expression of Usp42 during embryogenesis and spermatogenesis in mouse. Mech. Dev. (Gene Exp. Patterns) 7: 143-148.  (Corresponding author)

    *66. Noh, S.M., Kim, W.-K., Kim, S.J., Kim, J.M., Baek, K.-H., and Oh, Y.-K. (2007). Enhanced cellular delivery and transfection efficiency of plasmid DNA using positively charged biocompatible colloidal gold nanoparticles. Biochim. Biophys. Acta 1770: 747-752. (Corresponding author)

    *67. Baek, K.-H., Lee, E.-J., and Kim, Y.-S. (2007). Recurrent pregnancy loss: the key possible mechanisms. Trends Mol. Med. 13: 310-317. (Corresponding author)

    *68. Kim, D.C., Noh, S.M., Park, K.T., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2007). Transdermal delivery of porcine placenta extracts using linolenic acid-based emulsion formulations. J. Kor. Pharm. Sci. 37: 281-286. (Corresponding author)

    *69. Park, J.-M., Gu, B.-H., Lee, E.-J., Kim, J.-Y., Choi, S.-W., and Baek, K.-H. (2008). A single nucleotide polymorphism in exon 7 of sorbin and SH3-domain-containing-1 (SORBS1) in Korean PCOS patients. Mol. Med. Rep. 1: 93-97. (Corresponding author)

    70. Jin, Y.-H., Kim, Y.-J., Kim, D.-W., Baek, K.-H., Kang, B. Y., Yeo, C.-Y., and Lee, K.-Y. (2008). Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53. Biochem. Biophys. Res. Commun. 368: 690-695.

    *71. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Lee, S.-H., and Baek, K.-H. (2008). A single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil. Steril. 89: 1213-1220. (Corresponding author)

    *72. Lee, E.-J., Oh, B., Lee, J.-Y., Kimm, K., Park, J.-M., and Baek, K.-H. (2008). Association study between single nucleotide polymorphisms in the VEGF gene and polycystic ovary syndrome (PCOS). Fertil. Steril. 89: 1751-1759. (Corresponding author)

    *73. Park, J.-M., Lee, E.-J., Ramakrishna, S., Cha, D.-H., and Baek, K.-H. (2008). Association study for single nucleotide polymorphisms in CYP17A1 gene and polycystic ovary syndrome. Int. J. Mol. Med. 22: 249-254. (Corresponding author)

    *74. Kim, D.C., Noh, S.M., Kim, Y.B., Baek, K.-H., and Oh, Y.-K. (2008). Transdermal delivery of ceramide using sodium deoxycholate-based deformable liposomes. J. Kor. Pharm. Sci. 38: 319-323. (Corresponding author)

    *75. Lee, M.-Y., Ajjappala, B.S., Kim, M.-S., Oh, Y.-K., and Baek, K.-H. (2008). DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway. J. Cell. Biochem. 105: 1420-1429. (Corresponding author)

    *76. Ajjappala, B.S., Kim, Y.-S., Kim, M.-S., Lee, M.-Y., Lee, K.-Y., Ki, H.-Y., Cha, D.-H., and Baek, K.-H. (2009). 14-3-3γ is stimulated by IL-3 and promotes cell proliferation. J. Immunol. 182: 1050-1060. (Corresponding author)

    *77. Gu, B.H., and Baek, K.-H. (2009). Pro12Ala and His447His polymorphisms of PPAR-gamma are associated with polycystic ovary syndrome. Reprod. BioMed. Online, 18: 644-650. (Corresponding author)

    78. Ait-Ali, T., Wilson, A.W., Finlayson, H., Carre, W., Ramaiahgari, S.C., Westcott, D.G., Waterfall, M., Frossard, J.P., Baek, K.-H., Drew, T.W., Bishop, S.C., and Archibald, A.L. (2009). Functional analysis of the porcine USP18 and its role during porcine arterivirus replication. Gene 439: 35-42.
    *79. Choi, S.-W., Gu, B.-H., Ramakrishna, S., Park, J.-M., and Baek, K.-H. (2009). Association between a single nuclotide polymorphism in MTHFR gene and polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 145: 85-88. (Corresponding author)
    *80. Ajjappala, B., Kim, M.-S., Kim, E.-Y., Kim, J.-H., Kang, I.-C., and Baek, K.-H. (2009). Protein chip analysis of pluripotency associated proteins in NIH3T3 fibroblast. Proteomics 9: 3968-3978. (Corresponding author)
    81. Jo, A.-Y., Kim, M.-Y., Lee, H.-S., Rhee, Y.-H., Lee, J.-E., Baek, K.-H., Park, C.-H., Koh, H.-C., Shin, I., Lee, Y.-S., and Lee, S.-H. (2009). Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant Nurr1 mutant. Stem Cells 27: 2238-2246.
    *82. Gu, B.-H., and Baek, K.-H. (2009). Follicular-stimulating hormone receptor (FSHR) polymorphisms and polycystic ovary syndrome (PCOS). Fertil. Steril. 92: e55. (Corresponding author)

    *83. Baek, K.-H., and Ramakrishna, S. (2009). USP7 (ubiquitin specific peptidase 7 (herpes virus-associated)). Atlas Genet Cytogenet Oncol Haematol. 2009; 13(8): 576-579. (Corresponding author)

    84. Noh, S.M., Park, M.O., Shim, G., Han, S.E., Lee, H.Y., Huh, J.H., Kim, M.S., Bang, S.S., Kim, K., Kwon, I.C., Kim, J.-S., Baek, K.-H., and Oh, Y.-K. (2010). Pegylated poly-L-arginine derivatives of chitosan for effective delivery of siRNA. J. Control. Release, 145: 159-164.

    *85. Ramakrishnam, S., Suresh, B., Kang, I.-C., and Baek, K.-H. (2010). Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme. Hybridoma, 29: 311-319. (Corresponding author)

    *86. Choi, J.-H., Lee, M.-Y., Kim, Y., Shim, J.-Y., Han, S.-M., Lee, K.-A., Choi, Y.-K., Jeon, H.-M., and Baek, K.-H. (2010). Isolation of genes involved in pancreas regeneration by subtractive hybridization. Biol. Chem. 391: 1019-1029. (Corresponding author)

    *87. Gu, B.-H., Park, J.-M., and Baek, K.-H. (2010). Genetic variations of FSHR are associated with polycystic ovary syndrome. Int. J. Mol. Med. 26: 107-112. (Corresponding author)

    *88. Suresh, B., Ramakrishna, S., Lee, H.-J., Choi, J.-H., Kim, J.-Y., Ahn, W.-S., and Baek, K.-H. (2010). K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44. Cell Biol. Int. 34: 799-808.  (Corresponding author)

    *89. Suresh, B., Ramakrishna, S., Kim, Y.-S., Kim, S.-M., Kim, M.-S., and Baek, K.-H. (2010). Stability and function of mammalian lethal giant larvae-1 oncoprotein are regulated by the scaffolding protein RanBPM. J. Biol Chem. 285: 35340-35349. (Corresponding author)

    *90. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2011). The role of deubiquitinating enzymes in apoptosis. Cell. Mol. Life Sci. 68: 15-26. (Corresponding author)

    *91. Lan, L., Yun, J.-H., Lee, J.-H., Song, S., Choi, B.-C., and Baek, K.-H. (2011). Association study of +45G15G (T/G) and +276 (G/T) polymorphisms in the adiponectin gene with polycystic ovary syndrome. Int. J. Mol. Med. 27: 283-287. (Corresponding author)

    *92. Kim, M.-S., Ramakrishna, S., Lim, K.-H., Kim, J.-H., and Baek, K.-H. (2010). Protein stability of mitochondrial superoxide dismutase SOD2 is regulated by USP36. J. Cell. Biochem. 112: 498-508. (Corresponding author)

    *93. Ramakrishna, S., Suresh, B., Lee, E.-J., Lee, H.-J., Ahn, W.-S., and Baek, K.-H. (2011). Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J. Biol. Chem. 286: 10505-10514. (Corresponding author)

    *94. Kim, M.-S., Gu, B.-H., Song, S., Choi, B.-C., Cha, D.-H., and Baek, K.-H. (2011). ITI-H4, as a biomarker in the serum of recurrent pregnancy loss patients. Mol. Biosyst. 7: 1430-1440. (Corresponding author)

    *95. Kim, J.-H., Li, L., Yun, J.-H., Choi, B.-C., and Baek, K.-H. (2011). Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome. Mol. Med. Rep. 4: 747-751. (Corresponding author)

    *96. Ramakrishna, S., Suresh, B., Lim, K.-H., Cha, B.-H., Lee, S.-H., Kim, K.-S., and Baek, K.-H. (2011). PEST motif sequence regulating human NANOG for proteasomal degradation. Stem Cells Dev. 20: 1511-1519.  (Corresponding author)

    97. Bang, J.-Y., Kim, E.-Y., Kang, D.-K., Chang, S.-I., Han, M.-H., Baek, K.-H., and Kang, I.-C. (2011). Pharmaco-proteomic analysis of a novel cell-permeable peptide inhibitor of tumor-induced angiogenesis. Mol. Cell. Proteomics, Mol. Cell. Proteomics, 10: M110.005264

    *98. Choi, J.-H., Lee, M.-Y., Ramakrishna, S., Kim, Y., Shim, J.-Y. Han, S.-M., Kim, J.-Y., Lee, D.-H., Choi, Y.-K., and Baek, K.-H. (2011). LCP1 up-regulated by partial pancreatectomy supports cell proliferation and differentiation. Mol. BioSyst. 7: 3104-3111. (Corresponding author)

    *99. Yun, J.-H., Choi, J.-W., Lee, K.-J.,Shin, J.-S., and Baek, K.-H. (2011). The promoter -1031(T/C) polymorphism in tumor necrosis factor-alpha associated with polycystic ovary syndrome. Reprod. Biol. Endocrinol. 9: 131. (Corresponding author)

    *100. Baek, K.-H., and Suresh, B. (2012). RANBP9 (RAN binding protein 9). Atlas Genet Cytogenet Oncol Haematol. 2009; 16 (8): 549-551. (Corresponding author)

    *101. Suresh, B., Ramakrishna, S., and Baek, K.-H. (2012). Diverse roles of a scaffolding protein RanBPM. Drug Discov. Today, 17: 379-387. (Corresponding author)

    *102. Ramakrishna, S., Suresh, B., Bae, S.-M., Ahn, W.-S., Lim, K.-H., and Baek, K.-H. (2012). Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity. PLoS One, 7: e37772. (Corresponding author)

    *103. Yun, J.-H., Gu, B.-H., Kang, Y.-B., Choi, B.-C., Song, S., and Baek, K.-H. (2012). Association between INS-VNTR polymorphism and polycystic ovary syndrome in a Korean population. Gynecol. Endocrinol, 28: 525-528. (Corresponding author)

    *104. Baek, K.-H., Lee, H., Yang, S., Lim, S.-B., Lee, W., Lee, J.E., Lim, J.-J., Jun, K., Lee, D.-R., Chung, Y. (2012). Embryonic demise caused by targeted disruption of a cysteine protease Dub-2. PLoS One, 7: e44223. (Corresponding author)

    *105. Choi, J.-H., Lim, K.-H., Park, E., Kim, J.-Y., Choi, Y.-K., and Baek, K.-H. (2012). Glutamate-ammonia ligase and reduction of G0 population in PANC-1 cells. J. Cell. Biochem. 114(2): 303-313. (Corresponding author)

    *106. Kim, Y.-S., Gu, B.-H. Choi, B.-C. Kim, M.-S., Song, S., Yun, J.-H., Chung, M.-K., Choi, C.-H., and Baek, K.-H. (2012). Apolipoprotein A-IV as a novel gene associated with polycystic ovary syndrome. Int. J. Mol. Med. 31(3): 707-716. (Corresponding author)

    *107. Lim, K.-H., and Baek, K.-H. (2012). Deubiquitinating enzymes as therapeutic targets in cancer. Curr. Pharm. Des. 19(22) 4039-4052. (Corresponding author)

    *108. Park, J.-J., Yun, J.-H., and Baek, K.-H. (2013). Polyclonal and monoclonal antibodies for ubiquitin specific protease 20. Mono. Ant. Immuno. Immunoth. 32(3): 193-199. (Corresponding author)

    *109. Lim, K.-H., Ramakrishna, S., and Baek, K.-H. (2013). Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes. Cyt. Growth Factor Rev. 24(5): 427-431. (Corresponding author)

    *110. Li, L., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2013). Relationship between leptin receptor and polycystic ovary syndrome. Gene, 527(1): 71-74. (Corresponding author)

    111. Lee, K.W., Cho, J.G., Kim, C.M. Kang, A.Y., Kim, M., Ahn, B.Y., Chung, S.S., Lim, K.-H., Baek, K.-H., Park, K.S., Sung, J.-H., and Park, S.G. (2013). Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor gamma (PPARr) stability through its deubiquitinating activity. J Biol Chem, 288(46): 32886-32896.

    *112. Lim, K.-H., Kim, S.-R., Ramakrishna, S., and Baek, K.-H. (2014). Critical lysine residues of Klf4 required for protein stabilization and degradation. Biochem. Biophys. Res. Commun. 443(4): 1206-1210. (Corresponding author)

    *113. Ramakrishna, S., Kim, K.-S., and Baek, K.-H. (2014). Posttranslational modifications of defined embryonic reprogramming transcription factors. Cell Reprogram. 16(2): 108-120. (Corresponding author)

    *114. Ramakrishna, S., Suresh, B., and Baek, K.-H. (2015). Biological functions of hyaluronan and cytokine-inducible deubiquitinating enzymes. BBA - Rev. Cancer, 1855: 83-91 (Corresponding author)

    *115. Park, J.-J., Lim, K.-H., and Baek, K.-H. (2015). Annexin-1 regulated by HAUSP is essential for UV-induced damage response. Cell Death & Dis. 6:e1654. (Corresponding author)

    *116. Kim, S.-R., Kim, J.-O., Lim, K.-H., Yun, J.-H., and Han, I., and Baek, K.-H. (2015). Regulation of pyruvate kinase isozyme M2 is mediated by the ubiquitin-specific protease 20. Int. J. Oncol. 46: 2116-2124. (Corresponding author)

    *117. Li, L., Yun, J.-H., Yoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). 54G/C polymorphism of SREBF-1 gene is associated with polycystic ovary syndrome. Eur. J. Obs. Gyn. Reprod. Biol. 188: 95–99. (Corresponding author)

    *118. Park, J.-H., Li, L., and Baek, K.-H. (2015). Association of T869C polymorphism of transforming growth factor-β1 gene with polycystic ovary syndrome. Mol. Med. Rep. 12(3): 4560-4565. (Corresponding author)

    *119. Li, L., and Baek, K.-H. (2015). Molecular genetics of polycystic ovary syndrome: an update. Curr. Mol. Med. 15(4): 331-342. (Corresponding author)

    *120. Li, L., Ryoo, J.-E., Lee, K.-J., Choi, B.-C., and Baek, K.-H. (2015). Genetic Variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome. PLoS One. 10(4): e0123045. (Corresponding author)

    121. Schvartz, D., Bergsten, P., Baek, K.-H.. Barba De La Rosa, A., Cantley, J., Dayon, L., Finamore, F., Fontana, P., Gaudet, P., Goo, Y.A., Moulder, R., Goodlett, D., Johnson, J.D., Konvalinka, A., Mulde,r H., Priego-Capote, F., Sechi, S., Snyder, M., Tiss, A., Wiederkehr, A., Xenarios, I., Kussmann, M., and Sanchez, J-C. (2015). The human diabetes proteome project (HDPP): The 2014 update. Translational Proteomics. 8-9: 1-7.

    *122. Lim, K.-H., Park, J.-J., Gu, B.-H., Kim, J.-O, Park, S.-G, and Baek, K.-H. (2015). HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response. Sci. Rep. 5: 12793. (Corresponding author)

    *123. Kim, J.-O,, Kim, S.-R., Lim, K.-H., Kim, J.-H., Ajjappala, B., Lee, H.-J., Choi, J.-I., and Baek, K.-H. (2015). Deubiquitinating enzyme USP37 regulating oncogenic function of 14-3-3γ. Oncotarget, 6(34): 36551-36576. (Corresponding author)

    124. Kim, K. E., Cho, Y. S., Baek, K. S., Li, L., Baek, K.-H., Kim, J. H., Kim, H.-S., Sheen, Y. H. (2016). Lipopolysaccharide-binding protein plasma levels as a biomarker of obesity-related insulin resistance in adolescents. Kor. J. Pediatr. 59(5): 231-238.

    125. Ahn, H.-J., Kim, K.-S., Shin, K.-W., Lim, K.-H., Kim, J.-O., Lee, J.-Y., Kim, J., Park, J.-H., Yang, K.-M., Baek, K.-H., Ko, J.-J., and Park, K.-S. (2016). Ell3 induces p53 stabilization following CDDP treatment by modulating ubiquitin-dependent and -independent proteasomal degradation pathways in the breast cancer cells. Oncotarget, 6(42): 44523-44537.

    *126. Lim, K.-H., Song, M.-H., and Baek, K.-H. (2016). Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint. Cell Mol Life Sciences, 73(7): 1439-1455. (Corresponding author)

    *127. Lim, K.-H., Suresh, B., Park, J.-H., Kim, Y.-S., Ramakrishna, S., and Baek, K.-H. (2016). Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth. Oncotarget, 7(22): 14441-14457.

    128. Chung, S., Rho, S., Kim, G., Kim, S.-R., Baek, K.-H., Kang, M., and Lew, H. (2016). Human cord blood cells and chorionic plate-derived mesenchymal stem cells promote axon survival in an optic nerve crush rat model. Int. J. Mol. Med. 37(5): 1170-1180.

    *129. Baek, K.-H. (2016). Meet Our Editorial Board Member. Curr. Protein & Pept. Sci. 17(4): 1.

    *130. Lim, K.-H., Choi, J.-H., Park, J.-H., Cho, H.-J., Park, J.-J., Lee, E.-J., Li, L., Choi, Y.-K., and Baek, K.-H. (2016). Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A. Oncotarget, 7(23): 34759-34772.

    *131. Park, J.-H., Li, L., Choi, J.-W., and Baek, K.-H. (2016). The association of-429T>C and -374T>A polymorphisms in the RAGE gene with polycystic ovary syndrome. Int. J. Med. Sci. 13(6): 451-456.

    *132. Kwon, S.-K., Lee, D.-H., Kim, S.-Y., Park, J.-H., Choi, J.-H., and Baek, K.-H. (2017). Ubiquitin-specific protease 21 regulating the K48-linked polyubiquitination of NANOG. Biochem. Biophys. Res. Commun. 482: 1443-1448..

    *133. Kwon, S.-K., Kim, E.-H., and Baek, K.-H. (2017). RNPS1 is modulated by ubiquitin-specific protease 4. FEBS Lett. 591(2): 369-381.

    134. Kim, Y.-J., Hur, J., Cho, E.-H., Baek, K.-H., and Lee, K.-J. (2017). Prediction of gestational diabetes mellitus by unconjugated estriol levels in maternal serum. Int. J. Med. Sci. 14(2): 123-127.

    *135. Kwon, S.-K., Saindane, M., and Baek, K.-H. (2017). p53 stability is regulated by diverse deubiquitinating enzymes. BBA - Rev. on Cancer, 1868: 404-411 (Corresponding author)

    *136. Kim, S.-Y., Kwon, S.-K., Lee, S.-Y., and Baek, K.-H. (2018). Ubiquitin-specific protease 5 and OTU deubiquitinase 6A differentially expressed by the expression level of p53. Int. J. Oncol. 552: 1705-1714. (Corresponding author)

    137. Kim, J.H., Heo, J.S., Baek, K.S., Kim, S.-Y., Kim, J.H., Baek, K.-H., Kim, K.E., and Sheen, Y.H. (2018). Zonulin level, a marker of intestinal permeability, is increased in association with liver enzymes in young adolescents. Clin. Chim. Acta 481: 218-224.

    *138. Choi, J., and Baek, K.-H. (2018). Cellular functions of stem cell factors mediated by the ubiquitin-proteasome system. Cell. Mol. Life Sci. 75: 1947-1957. (Corresponding author)

    *139. Kim, S.-Y., Choi, J., Lee, D.-H., Park, J.-H., Hwang, Y.-J., and Baek, K.-H. (2018). PME-1 is regulated by USP36 in ERK and Akt signaling pathways. FEBS Lett. 592(9): 1575-1588. Corresponding author)

    140. Baek, K.-H. (2018). Regulation of protein degradation and homeostasis by the cytokine-inducible deubiquitinating enzymes. Int. J. Immunother Cancer Res. 4: 1-3. (Corresponding author)

    141. Kim, K.E., Heo, J. S., Han, S., Kwon, S.-K., Kim, S.-Y., Kim, J.H., Baek, K.-H., and Sheen, Y. H. (2018). Blood concentrations of lipopolysaccharide-binding protein, high-sensitivity C-reactive protein, tumor necrosis factor-α, and Interleukin-6 in relation to insulin resistance in young adolescents. Clin. Chim. Acta 486: 115-121.

    *142. Li, L., Choi, B.-C., Ryoo, J.E., Song, S.-J., Pei, C.-Z., Lee, K.Y., Paek, J., and Baek, K.-H. (2018). Opposing roles of inter--trypsin inhibitor heavy chain 4 in recurrent pregnancy loss. EBioMedicine, in press.

    More Info.
    Xiangrong Song
    Associate Professor
    Sichuan University

    Research Interest: New delivery systems for macromolecular drugs and small molecular drugs.

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    Majella E Lane
    Skin Research Group UCL School of Pharmacy
    UCL School of Pharmacy

    Research Interest: Skin Formulation, Permeation, Topical Delivery, Transdermal Delivery, Nanoparticles, Hair Follicles.

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    Chul Huh
    Electronics and Telecommunications Research Institute

    Research Interest: Nanophotonics based on Si nanocrystals; Optical biosensors; Flexible and implantable biosensors; Photonic devices based on GaN-based semiconductors

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