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International Journal of Sexual and Reproductive Health Care

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    • Language of Full TextEnglish
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Publisher Information

Editorial Board Join as Editor

Chung-Yi Chen
Professor and Dean
School of Medical and Health Sciences
Fooyin University
Taiwan
xx377@fy.edu.tw
IJSRHC

Biography: President Chen obtained PhD in 1999 at Kaohsiung Medical University. Currently teaches in Fooyin University, as most young is also the most senior professors and deans. The past 20 years, he has his scientific interests focused on life-threatening diseases, including traditional Chinese medicine used for cancer research. Analysis in recent year’s major active ingredients such as ginger, pepper and cinnamon used in gastrointestinal cancer, anti-inflammatory, antioxidant, antiparasitic, and other topics. President Chen specializes in isolation, purification and structural analysis of active components of plants. President Chen directed against active constituents of oral cancer, liver cancer, and rectal cancer. President Chen was just over 45 years old, but his work has more than 220 papers, Taiwan one of the young talents. Professor Chen was invited more than 170 kinds of Journal editorial boards. Professor Chen won numerous awards at home and abroad, from 2015, was awarded the lifetime achievement award; from 2016 was awarded the health care & biotechnology merit award. 

Research Interest: Pharmacy

No. of Publications: 230


More Info.
Ayman Abdel-Aziz Swelum
Associate Professor
Theriogenology & animal production
Zagazig University & King Saud University
Egypt & Saudi Arabia
aymanswelum@yahoo.com
IJSRHC

Biography:

Ayman Abdel-Aziz Swelum BVS, MS, PhD 

Dr. Swelum graduated in 2002 with a bachelor's degree in veterinary medicine from faculty of veterinary medicine, Zagazig University in Egypt. He earned his MS (2006) and PhD (2010) in Theriogenology (Reproductive Medicine and surgery) from Zagazig University.

Dr. Swelum started his career in Egypt and maintains an ongoing affiliation with the university there, teaching and doing research on large animal Theriogenology. Dr. Swelum worked as Assistant Professor of Theriogenology at Zagazig University until 2010. He then accepted a position Assistant Professor of Theriogenology at King Saud University. He is now an associated professor and he founded the Theriogenology research team that providing clinical service and conducting research in animal reproduction. 

Dr. Swelum devoted most of his career to teaching Theriogenology and conducting applied research on animal reproduction. He served as the resident veterinarian and veterinary consultant to King Abdul-Aziz Arabian Horse Center and Germplasm Bank and Artificial Insemination center in Saudi Arabia. He received several awards recognizing his excellence in teaching, research quality and clinical practice including International Publication award from Zagazig University. Dr. Swelum provided large animal reproductive medicine continuing education programs for veterinarians around the world. He is the author of over 60 scientific research articles. Dr. Swelum is the author of one book and several book chapters on animal reproductive medicine. He is an active member of many societies and association as the International Embryo Transfer Society.


Research Interest: Animal reproduction

URL of their official website:

http://www.staffdata.zu.edu.eg/ar/ShowData/18313
http://fac.ksu.edu.sa/aswelum

List of Publications:

A- Thesis:
1. Swelum AA (2009): Some trials for improving cryopreservation of buffalo bull semen. Ph.D.V.Sc. Theriogenology, Fac. Of Vet. Med., Zagazig Uni.
2. Swelum AA (2006): Some studies for improving preservation and fertility of buffalo bull semen. M.V.Sc. Theriogenology, Fac. of Vet. Med., Zagazig Uni.
B- Peer-Reviewed papers:
1. Swelum AA, I Saadeldin, Mona Elsafadi, Abdullah F Moumen, Faisal A Alzahrani, Amer Mahmood, Musaad Alfayez, Abdullah N Alowaime (2017). Isolation and characterization of the trophectoderm from the Arabian camel (Camelus dromedarius). Placenta 57, 113-122
2. Swelum AA, I Saadeldin, H Zaher, SAM Alsharifi, A Alowaimer (2017). Effect of sexual excitation on testosterone and nitric oxide levels of water buffalo bulls (Bubalus bubalis) with different categories of sexual behavior and their correlation with each other. Animal Reproduction Science 181:151-158.
3. El-Zahar H, Zaher H, Alkablawy A, Alsharif SAM,  Swelum AA (2017). Monitoring the changes in certain hematological and biochemical parameters in camels (Camelus Dromedaries) during postpartum period. journal of fertility biomarkers 1 (1), 47-54
4. Swelum AA, Zaher H, Amin SE, Eidaroos A, Hazzaa AM (2017). Factors Affecting Incidence of Uterine Torsion in Egyptian Buffaloes (Bubalus bubalis) and its Response for Rolling. Journal of Buffalo Science 6 (1), 28-34
5. Swelum AA, I Saadeldin, H Yaqoob, A Alowaimer (2017). Morphometric assessment of in vitro matured dromedary camel oocytes determines the developmental competence after parthenogenetic activation. Theriogenology 95, 141–148
6. Swelum AA, I Saadeldin, H Yaqoob, A Alowaimer (2017). Optimizing camel (Camelus dromedarius) oocytes in vitro maturation and early embryo culture after parthenogenetic activation. Small ruminant research 153: 81-86.
7. Hany A. M. Zaher, Swelum AA, Sawsan A. M. Alsharif, Ayman H. Alkablawy, Alaa B. Ismael (2017). Seroprevalence of chlamydiosis in Abu Dhabi dromedary camel (Camelus dromedarius) and its association with hematobiochemical responses towards the infection. J Adv Vet Anim Res 2017; 4(2): 175-180.
8. Abdelmoneim TS, Brooks PH, M Afifi, Swelum AA (2017). Sequencing of growth hormone gene for detection of polymorphisms and their relationship with body weight in Harri sheep. Indian Journal of Animal Research 51 (2): 205-2011. 
9. IM Saadeldin, A Abdelfattah-Hassan, Swelum AA (2017). Feeder Cell Type Affects the Growth of In Vitro Cultured Bovine Trophoblast Cells. BioMed Research International Volume 2017 (2017), Article ID 1061589, 6 pages.
10. Swelum AA, Faisal Alshamiry, Ahmed El-Waziry, Mohamed Ali, Tarek Shafey, Mohamed Abouheif (2017). Effects of Feeding Frequency on Plasma Metabolite Concentration and Production Cost of Feed-restricted Lambs. Journal of Animal nutrition & Feed Technology, 17(2): 279- 291.
11. Swelum AA, AA Moumen, A Alowaimer (2017): The effect of withdrawal timing of controlled internal drug release (CIDR) on ewe reproductive performance. Reproduction, Fertility and Development 29 (1), 119-119.
12. Swelum AA, I Saadeldin, H Ba-Awadh, A Alowaimer (2017). Effect of melatonin treatment on libido and endocrine function of dromedary camel bulls out of the breeding season. Reproduction, Fertility and Development 29 (1), 163-164.
13. Ahmed Hossam Mahmoud, Swelum AA, Mohammad Abul Farah, Khalid Alanazi,
Ahmed Rady, Mahmoud Salah, Nabil Amor and Osam Mohammed (2017). Genetic diversity among Sawakni, Berberi and Najdi sheep breeds in Saudi Arabia using microsatellites markers. African Journal of Biotechnology 16 (4), 171-178.
14. Swelum AA, IM Saadeldin, AN Alowaimer, A Mahmoud, MA Abouheif (2017). Impacts of restricted feeding and realimentation on bone development and plasma concentrations of bone-specific biomarkers in lambs. J. Anim. Feed Sci. 26(2):116–122.
15. Swelum AA, Ayadi M, Alhidary I, Alowaimer A, Abouheif M (2017). The relationships between body fatness, leptin, testosterone and reproductive performance in ram lambs as affected by level and frequency of feeding. Theriogenology 89:79–85
16. Zaher H, Swelum AA, Eidaroos AS, Labib F M (2017). The nitric oxide serum level and combined utero-placental thickness in buffalo (Bubalus bubalis) affected by pregnancy pathology. Theriogenology 88 :118–123.
17. Abouheif M, Baismael S, Swelum AA (2016). Effect of halophyte Salicornia bigelovii Torr and graded levels of dietary crude protein on feed performance and carcass traits of camels. Revista Brasileira de Zootecnia 45(11):704-708, 2016.
18. Ismael AB, Swelum AA, Khalaf AF, Alowaimer AN (2016). First evidence of natural anaplasmosis in Camelus dromedarius in Saudi Arabia. Journal of Camel Practice and Research 23 (1): 95-100.
19. Abouheif M, Al-Sornokh H, Swelum AA, Shafey T, Mahmoud A, Alshamiry F, Haroon R Effects of intake restriction and realimentation on diet digestion and ruminal fermentation by growing lambs. Global Advanced Research Journal of Agricultural Science 5 (4), 126-131.
20. Ismael AB, Swelum AA, Mostafa SAH, Alhumiany ARA (2016). Latex agglutination using the periplasmic proteins antigen of Brucella melitensis is a successful, rapid, and specific serodiagnostic test for ovine brucellosis. International journal of immunopathology and pharmacology 29 (3), 480-487.
21. Ismael AB, Swelum AA, Nassan MA (2016). Development of Improved Preventive and Treatment Strategies for Controlling of Toxoplasmosis in Saudi Arabia. American Journal of Infectious Diseases 12 (2), 50-56.
22. Swelum AA, Mouamen A, Alowaimer A (2016). Effect of 6 times reusing of CIDR short term (6 days) on hormonal and reproductive performance. Reproduction, Fertility and Development 28 (2), 136-136.
23. Abd El-Hafez SM, Ismael AB, Swelum AA, Mohamed EH, Alhumiany AA (2015). Development of a rapid and specific latex agglutination test for the serodiagnosis of camel brucellosis using a Brucella melitensis periplasmic protein antigen. Global Veterinaria 15 (3): 260-267.
24. Swelum AA, Alowaimer AN (2015). The efficacy of controlled internal drug release (CIDR) in synchronizing the follicular wave in dromedary camels (Camelus dromedarius) during the breeding season. Theriogenology 84 (9): 1542-1548.
25. Al-Samawi KA, Al-Hassan MJ, Swelum AA (2015). Diagnostic reliability of enzymatic-immunoassayed serum pregnancy associated glycoproteins in detecting early pregnancy compared to other screening measures in Aardi goats (Capra hircus) in Saudi Arabia. Indian Journal of Animal Research, 49 (5): 680-686.
26. Swelum AA, Al-Owaimer AN, Abouheif MA (2014). Comparison between the efficiency of 30-mg flurogestone acetate intravaginal sponge (FGA-30) and controlled internal drug release (CIDR) to synchronize oestrus in ewes. Reproduction, Fertility and Development 27(1) 101-102.
27. Swelum AA, Alowaimer AN, Abouheif MA (2015). Use of fluorogestone acetate sponges or CIDR for estrus synchronization in ewes: effects of hormonal profiles and reproductive performance, Theriogenology 84 (4):498-503.
28. Swelum A, Ismael A, Abd-El-Hafez S, Alhumiany A. A comparison between using of Buffered Plate Agglutination Test (BPAT), Rose Bengal Plate Test (RBPT) and Serum Agglutination Test (SAT) for diagnosis of brucellosis in dromedary camel. 4th Conference of ISOCARD “Silk Road Camel: The Camelids, Main Stakes For Sustainable Development” June 8-12, 2015 Almaty, Kazakhstan p. 270-272.
29. Abouheif M, Al-Sornokh H, Swelum AA, Yaqoob H, Al-Owaimer A (2015). Effect of different feed restriction regimens on lamb performance and carcass traits. Revista Brasileira de Zootecnia c 44(3):76-82.
30. Al-Samawi KA, Al-Hassan MJ, Swelum AA (2014). Thermoregulation of Female Aardi Goats exposed to Environmentally Heat Stress in Saudi Arabia. Indian Journal of Animal Research, 48(4): 344 – 349.
31. Swelum AA, Ismael AB, Khalaf AF, Abouheif MA (2014): Clinical and Laboratory Findings Associated to Babesiosis in Dromedary Camels. Bulletin of the Veterinary Institute in Pulawy, 58: 229-233.
32.  Al-Owaimer AN, Swelum AA, Yaqoob SH, Hussein ES, Abouheif MA (2014). Effects of the FecB allele on Body Weights of Naeimi and Naeimi Crossbred Lambs. Journal of Animal and Veterinary Advances, 13(7): 449-453
33. Ismael AB, Swelum AA, Khalaf AF, Abouheif MA (2014). Clinical, Haematological and Biochemical Alterations Associated with an Outbreak of Theileriosis in Dromedary Camels. Pakistan Vet Journal, 34(2): 209-213.
34. Swelum AA, Al-Owaimer AN, Abouheif MA (2014). Effects of breed and number of embryos transferred on the efficacy of MOET in sheep. Journal of Animal and Veterinary Advances 13 (2): 98-103.
35. Swelum AA, Al-Owaimer AN (2013). Comparison of the use of cephapirin and oxytetracycline for the treatment of clinical endometritis in the camel (Camelus dromedarius): A field study. Journal of Animal and Veterinary Advances 12 (4): 527-532.
36. Swelum AA, Amin SE, Eidaroos A, Hazzaa AM (2012). Prognosis prediction of uterine torsion mechanical treatment (rolling) after estimation of calcium and creatinine level in the serum of buffaloes (bubalus bubalis). Theriogenology 78:1048–1055.
37. Swelum AA, Mansour HA, El-Sayed AA, Amer HA (2011). Comparing ethylene glycol with glycerol for cryopreservation of buffalo bull semen in egg-yolk containing extenders. Theriogenology 76: 833–842.
38. Swelum AA, Mansour HAH, El-Sayed AA and Amer HA. (2009): Comparison between the Effect of Ethylene Glycol and Glycerol in the Freezability of Buffalo-Bull Spermatozoa in Tris or Milk Egg-Yolk Extenders. Zag. Vet. J. 37(4): 88-96.
39. Amer H., Mansour H., El-Sayed A., Swelum AA (2008): Influence of filtration or centrifugation of semen diluent on viability of chilled buffalo bull semen. Journal of STOČARSTVO 62(5):351-366.
C- Peer-Reviewed Abstracts presented at International Conferences:
40. Swelum AA, AA Moumen, A Alowaimer (2017): The effect of withdrawal timing of controlled internal drug release (CIDR) on ewe reproductive performance. 2017 IETS. 43rd Annual Conference. Renaissance Austin Hotel Austin, Texas January 14-17.
41. Swelum AA, I Saadeldin, H Ba-Awadh, A Alowaimer (2017). Effect of melatonin treatment on libido and endocrine function of dromedary camel bulls out of the breeding season. 43rd IETS Annual Conference. Renaissance Austin Hotel Austin, Texas January 14-17, 2017.
42. Swelum AA, Majdi Bahady, Islam M. Saadeldin, Abdullah N. Alowaimer (2017). Effect of supplementing camel or buck seminal plasma to TRIS-egg yolk extender on chilled semen preservation in rams. The 31st Meeting of Saudi Biological Society: Human and Environmental Development in Vision 2030, (18-20 April, 2017)) Hosted by Umm Al-Qura University, Makkah, Saudi Arabia.
43. Swelum AA, Zaher H, Alkablawy A, Ismael A (2017). Clinical and Confirmatory Diagnosis of Natural Chlamydiosis in Camelus Dromedaries. The 31st Meeting of Saudi Biological Society: Human and Environmental Development in Vision 2030, (18-20 April, 2017)) Hosted by Umm Al-Qura University, Makkah, Saudi Arabia.
44. Swelum AA, Mouamen A, Al-Owaimer AN. Effect of 6 times reusing of controlled internal drug release (CIDR) for short term (6 days) on progesterone level and reproductive performance of Awassi ewes. 42nd IETS Annual Conference, Louisville, Kentucky, from January 23 to 26, 2016.
45. Swelum AA, Al-Owaimer AN. Efficacy of PRID®DELTA to Synchronize Estrus in Dromedary Camels (Camelus Dromedarius) During Breeding Season. 32nd World Veterinary Congress, Istanbul, Turkey; 13-17 September 2015 p. 122.
46. Swelum AA, Al-Owaimer AN. Serum progesterone levels in dromedary camels treated with progesterone-controlled internal drug-release (CIDR). 4th Conference of ISOCARD “Silk Road Camel: The Camelids, Main Stakes For Sustainable Development” June 8-12, 2015 Almaty, Kazakhstan p. 385.
47. Yaqoob H, Swelum AA, Al-Owaimer AN. Effect of activation method on parthenogenetic embryo development of zona free and zona-intact camel (Camelus Dromedaries) oocytes. 4th Conference of ISOCARD “Silk Road Camel: The Camelids, Main Stakes For Sustainable Development” June 8-12, 2015 Almaty, Kazakhstan p. 386-387.
48. Swelum A., Mouamen A, Al-Owaimer A (2015). Serum estradiol levels in dromedary camels treated with progesterone-controlled internal drug-release. The 30th Meeting of Saudi Biological Society: Economics of the Red Sea and their Development 18-20 Jumada Al-Akhira, 1436 H (7-9 April, 2015) Hosted by University of Tabuk, Tabuk, Saudi Arabia.
49. Alaa B. Ismael, Salama M. Abd El Hafez, Swelum AA, Essam H. Mohamed and Abdel-Rahman A. Alhumiany. Development of a rapid and specific latex agglutination test for the serodiagnosis of camel brucellosis. The 30th Meeting of Saudi Biological Society: Economics of the Red Sea and their Development 18-20 Jumada Al-Akhira, 1436 H (7-9 April, 2015) Hosted by University of Tabuk, Tabuk, Saudi Arabia.
50. Swelum AA, Al-Owaimer AN, Abouheif MA (2014). Comparison between the efficiency of 30-mg flurogestone acetate intravaginal sponge (FGA-30) and controlled internal drug release (CIDR) to synchronize oestrus in ewes. 41st Annual Conference of the International Embryo Transfer Society Reproductive Performance: At the Crossroads of Genetics and the Environment, Versailles, France, January 10–13, 2015.
51. Swelum AA, Al-Owaimer AA and Abouheif MA (2014). Comparison between the effect of hCG and GnRH analogue (buserelin) treatment post laparoscopic insemination on reproductive performance of ewes. World Congress of Reproductive Biology 2014 2—4 September 2014 EICC, Edinburgh, UK. P309.
52. Swelum AA, Al-Owaimer AN, Abouheif MA (2014). Effects of breed and number of embryos transferred on the efficacy of MOET in sheep. The International Conference on Veterinary and Biomedical Sciences (ICVBS), 24-25 March, 2014, Istanbul, Turkey.
53. Ismael AB, Swelum AA, Khalaf AF (2014). Clinical and Laboratory Findings of Natural Paratuberculosis in Dromedaries (Camelus dromedarius) in Saudi Arabia. The 29th Meeting of Saudi Biological Society: Environment and Development in the Gulf Region 25-27 February, 2014, University of Dammam, Dammam, Saudi Arabia.
54. Swelum AA, Ismael AB, Khalaf AF (2014). Clinical, Haematological and Biochemical Alterations Associated with a Natural Trypanosomosis in Dromedaries (Camelus dromedarius) in Saudi Arabia. The 29th Meeting of Saudi Biological Society: Environment and Development in the Gulf Region 25-27 February, 2014, University of Dammam, Dammam, Saudi Arabia.
55. Swelum AA, Zaher HA, Eidaroos A, Mohammed FL (2013). The Relationship between Nitric Oxide Level, Combined Utero-Placental Thickness (CUPT) in Addition to Cytotrophoblastic Cells and Pathology of Pregnancy in Buffalo (Bubalus bubalis). The 10th World Buffalo Congress and the 7th Asian Buffalo Congress, 6-8 May, 2013, Hilton Phuket Arcadia Resort and Spa, Phuket, Thailand.
56. Swelum AA, Mansour HA, Elsayed AA (2013). Comparison between Centrifuged Triladyl® and Tris Milk Egg Yolk with Glycerol or Ethylene Glycol Diluent for Cryopreservation of Buffalo Bull Semen. The 10th World Buffalo Congress and the 7th Asian Buffalo Congress, 6-8 May, 2013, Hilton Phuket Arcadia Resort and Spa, Phuket, Thailand.
57. Swelum AA (2013). Comparison of the use of cephapirin and oxytetracycline for the treatment of endometritis in she-camel (Camelus dromedarius): A field study. Conference of sustainability of camel population and production (CSCPP), 17-20 February, 2013, Collage of Agriculture and Food Sciences, king Faisal University, Alahsa, Saudi Arabia.
58. Swelum AA, Ismael AB, Khalaf AF, Abouheif MA (2013). Clinical, Haematological and Biochemical Alterations Induced by Natural Babesiosis in Dromedary Camels. Conference of sustainability of camel population and production (CSCPP), 17-20 February, 2013, Collage of Agriculture and Food Sciences, king Faisal University, Alahsa, Saudi Arabia.
59. Ismael AB, Swelum AA, Khalaf AF (2013). Clinical and laboratory Findings of Outbreak of Theileriosis in Saudi Arabian Dromedary Camels. Conference of sustainability of camel population and production (CSCPP), 17-20 February, 2013, Collage of Agriculture and Food Sciences, king Faisal University, Alahsa, Saudi Arabia.
60. Swelum AA, Alowaimer AN, Abouheif MA. Effect of insemination method and synchronization regime on conception rate, litter size and sex ratio of Najdi ewes during the summer season. The 28th Meeting of Saudi Biological Society: Eco-tourism and sustainable Development, 9-10 April, 2013, Hail University, Hail, Saudi Arabia.
61. Swelum AA, Abouheif MA, Alowaimer AN. Comparison the success of multiple ovulation and embryo transfer (MOET) in Najdi and Nuami ewes. The 28th Meeting of Saudi Biological Society: Eco-tourism and sustainable Development, 9-10 April, 2013, Hail University, Hail, Saudi Arabia.
62. Abouheif MA, Swelum AA, Al-Saiady MY, Al-Owaimer AN, Shafey TM. Effects of feed restriction on biological markers of bone in growing lambs. The 28th Meeting of Saudi Biological Society: Eco-tourism and sustainable Development, 9-10 April, 2013, Hail University, Hail, Saudi Arabia.
63. Swelum AA, Ismael AB, Khalaf AF. Clinical and Laboratory Findings of natural Brucellosis in Saudi Arabian Dromedary Camels. The 28th Meeting of Saudi Biological Society: Eco-tourism and sustainable Development, 9-10 April, 2013, Hail University, Hail, Saudi Arabia.
64. Ismael AB, Swelum AA, Khalaf AF. Clinical and Laboratory Findings of natural Anaplasmosis in Saudi Arabian Dromedary Camels. The 28th Meeting of Saudi Biological Society: Eco-tourism and sustainable Development, 9-10 April, 2013, Hail University, Hail, Saudi Arabia.
65. Swelum AA, Zaher H A, Eidarous A, Labib F (2012). The relationship between pathology of pregnancy and combined utero placental thickness (CUPT) in buffalo (Bubalus bubalis). The 27th Meeting of Saudi Biological Society, Economics of Environment and Natural Resources, 6-8 March, 2012, Jazan University, Jazan, Saudi Arabia.
66. Ismail AB, Swelum AA, Nassan MA (2012). Diagnosis of hemorhagic septecimia in dairy cattle and its control. The 27th Meeting of Saudi Biological Society, Economics of Environment and Natural Resources, 6-8 March, 2012, Jazan University, Jazan, Saudi Arabia.
D- Books
1.    Ayman Swelum (2011). Some Trials for Improving Cryopreservation of Buffalo-Bull Semen: Artificial Insemination Using Cryopreserved Buffalo Bull Semen in Different Diluents and Cryoprotectant.
Publisher: LAP LAMBERT Academic Publishing, ISBN: 3838339916
APRIL 2011.
https://www.morebooks.de/store/fr/book/some-trials-for-improving-cryopreservation-of-buffalo-bull-semen/isbn/978-3-8383-3991-7
2.    Sharing in theoretical and practical books of Gynecology. Department of Theriogenology, Faculty of veterinary medicine, Zagazig University.
3.    Sharing in theoretical and practical books of Obstetric. Department of Theriogenology, Faculty of veterinary medicine, Zagazig University.
4.    Sharing in theoretical and practical books of Andrology. Department of Theriogenology, Faculty of veterinary medicine, Zagazig University.
5.    Sharing in theoretical and practical books of Artificial insemination and assisted reproductive technology. Department of Theriogenology, Faculty of veterinary medicine, Zagazig University.

More Info.
Giannina Satta
Professor
Department of Medical Sciences and Public Health
University of Cagliari
Italy
gianninasatta@tiscali.it
IJSRHC

Giannina Satta is currently a research fellow of  Department of Medical Sciences and Public Health, University of Cagliari at Occupational Medicine Section since 2004. She obtained her Bachelor of in Biological Sciences (cum laude) at University of Cagliari in November 2000.  Her research interests lie in the field of environmental and occupational risk factors for lymphoma subtypes with a strong emphasis on integrating epidemiology, high quality exposure assessment, biological monitoring, molecular biology into multidisciplinary investigations and industrial toxicolgy.

 In her last years, she focused in particular on the exploration of new methods for quantifying exposure assessment to  ionizing and non ionizing radiation and risk of lymphomas. She has collaborated actively in various research projects. Authors of 70 publications, including 15 in international peer-reviewed journals. She is also a member committee of the Interlymph Consortium, a world wide network of lymphoma studies promoted by the U.S. National Cancer Institute and member of MODERNET (Monitoring trends in Occupational Diseases and tracing new and Emerging Risks in a NETwork).

Research Interest: Environmental Epidemiology, Industrial Toxicology, and Occupational Health

URL of their official website: http://dipartimenti.unica.it/scienzemedicheesanitapubblica/

Publications:

1.    Cocco P, Moore PS,  Ennas MG, Tocco MG, Ibba A, Mattuzzi S, Meloni M, Monne M, Piras G, Collu S, Satta G, Zucca M, Scarpa A, and Flore C. Effect of urban traffic, individual habits, and genetic polymorphisms on background urinary 1-hydroxypyrene excretion. Ann Epidemiol 2007;17:1-8. PMID:16406813
2.    Bocchetta A, Fadda D, Satta G, Del Zompo M, Gessa GL, Cocco P. Long-Term Lithium Treatment and Survival From External Causes Including Suicide. J Clin Psychopharmacol. 2007;27:544-546. PMID: 17873708
3.    Kiran S, Cocco P, Mannetje A, Satta G, D'Andrea I, Becker N, de Sanjosé S, Foretova L, Staines A, Kleefeld S, Maynadié M, Nieters A, Brennan P, BoffettaP. Occupational exposure to ethylene oxide and risk of lymphoma. Epidemiology.2010 ;21(6); pp 905-10. PMID: 20811284
4.    Budroni M, Sechi O, Cesaraccio R, Pirino D, Fadda Alessandra, Grottin S, Flore MV, Sale P, Satta G, Cossu A, Tanda F, Cocco P. Incidenza di patologie neoplastiche nei lavoratori del complesso petrolchimico di Porto Torres, 1990-2006. MedLav  2010; 101, 3: 189-198.PMID: 20812660
5.    Fustinoni S.,Campo L, Satta G, Campagna M, Ibba A, Tocco MG, Atzeri S, Avataneo G, Flore C, Meloni M, Bertazzi PA, Cocco P. Environmental and lifestyle factors affect benzene uptake biomonitoring of residents near a petrochemical plant. Environ Int 39 2012,pp 2–7.  PMID: 22208737
6.    Carugno M, Pesatori AC, Dioni L, Hoxha M, Bollati V, Albetti B, Byun HM, Bonzini M, Fustinoni S, Cocco P, Satta G, Zucca M, Merlo DF, Cipolla M, Bertazzi PA, Baccarelli A. Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure. Environ Health Perspect.2012; 120(2) pp 210-215. PMID: 22005026
7.    Zucca M, Ugalde J, Arteaga FS, Biggio G, Flore V, Nonne T, Satta G, Blangiardo M, Cocco P, Ennas MG. Leukemia in children and youths of the Azuay province, Ecuador: 2000-2010. Int J Environ Health Res. 2012;23(1); pp 58-65. PMID: 22769047
8.    P Cocco , G Satta, S Dubois, M Pilleri, T Nonne, M Zucca,  A ‘t Mannetje, N Becker, S de Sanjosé, L Foretova, A Staines, M Maynadié, A Nieters, P. Brennan, L Miligi, MG Ennas, and P Boffetta. Lymphoma risk and occupational exposure to pesticides: results of the Epilymph study. Occup Environ Med 2012; 70(2);  pp 91-98.   PMID: 2311721
9.    P Cocco, G Satta, I. D’Andrea,TNonne, G Udas, M Zucca, A. ‘t Mannetje, N Becker, S de Sanjosé, L Foretova, A Staines, M Maynadié, A Nieters, P Brennan,1 MG Ennas, and P Boffetta. Lymphoma risk in livestock farmers: results of the Epilymph study .Int. J. Cancer2012; 132(11); pp 2613-8. PMID: 23065666
10.    M Campagna, G Satta, L Campo, V Flore, A Ibba, M Meloni, MG Tocco, G Avataneo, C Flore, S Fustinoni, P Cocco. Biological monitoring of low-level exposure to benzene. Med Lav  2012 103 (5) : 338-346. PMID: 23077794
11.    MG Ennas,  M Zucca,G Satta,T Nonne,Angelucci E, A Gabbas,M Rais,A Scarpa,P Cocco. Do the Matrix Metalloproteinase-1 and the Glucose-6-phosphate dehydrogenase  gene polymorphisms interact in promoting lymphoma development? Leuk Lymphoma. 2013 Mar 13. PMID: 23485169
12.    M Campagna, G Satta, L Campo, V  Flore, A Ibba, M Meloni, MG Tocco, G Avataneo, C Flore, S Fustinoni, P Cocco. Analysis of potential influence factors on background urinary benzene concentration among a non-smoking, non-occupationally exposed general population sample. Int Arch Occup Environ Health 2013; pp 1-7;  PMID: 24370553
13.    P Cocco, M Zucca, S Sanna, G Satta, T Nonne, A Angelucci, A Gabbas, M Rais, G Malpeli, M Campagna , A Scarpa e M G Ennas. N-acetyl transferase polymorphisms are associated with risk of lymphoma subtypes. HematolOncol 2015.; 34 (2). PMID: 25689677
14.    M Campagna, G Satta, D Fadda, S Pili, P Cocco. Male fertility following occupational exposure todichlorodiphenyltrichloroethane (DDT). Environment International 77 (2015) 42–47. PMID: 25645380
15.    P Cocco, M G Zucca, S Sanna, G Satta, E Angelucci, A Gabbas, M Monne, M Campagna, A Scarpa;M G Ennas. Interaction between Dietary and Lifestyle Risk Factors and N-Acetyltransferase Polymorphisms in B-Cell Lymphoma Etiology. J Environ Anal Toxicol 2015, 5:5 ISSN :2161-0525.


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Wei Wu
Assistant Professor
School of Public Health
Nanjing Medical University
China
epigenetic@126.com
IJSRHC

Biography:

Wei Wu is an Associate Professor in the Institute of Toxicology, School of Public Health at Nanjing Medical University, China. He received his PhD in Toxicology from Nanjing Medical University in 2012. Dr Wu’s research has focused on 1) Environmental, genetic and epigenetic risk factors on human reproductive health and fetal Growth; 2) Gene-environment interactions in reproductive & endocrine systems; 3) Representative EDCs reproductive endocrine toxicity and its mechanism. He has a wide range of teaching and consulting experiences including Toxicology. Areas of expertise and interests are Toxicology, Male Infertility, Pregnancy complications, Fetal Growth, Epigenetics, Endocrine Disrupting Chemicals, Transgenerational Effect, and Reproduction and Development.

Research Interest: Reproductive and Developmental Toxicology

 Research Grant Details:
1.    National key research and development project: The establishment and basic research for application of China Assisted reproductive birth cohort population and the offspring cohort of the Chinese population. 2016/7-2021/6, ¥280900.
2.    National Natural Science Foundation of China (81673217): The study of role and molecular mechanisms of the DSTF1/miR-125-3p/Fstl3 pathway in the transgenerational spermatogenic failure caused by prenatal DBP exposure. 2017/1-2020/12, ¥600000.
3.    China Postdoctoral Science Foundation (2015T80571): The role and molecular mechanisms of human miR-483-3p in the BP-3 induced fetal macrosomia. 2015/7-2017/6, ¥150000.
4.    National Natural Science Foundation of China (81302457): Effect and mechanism of miR-17-92 gene cluster in spermatogenic failure induced by genistein exposure. 2014/1-2016/12, ¥240000
5.    Jiangsu Natural Science Foundation (BK20130894): The role and molecular mechanisms of miR-200s family in spermatogenic failure induced by genistein exposure. 2013/7-2016/6, ¥200000.
6.    China Postdoctoral Science Foundation (2013M531388): The role and molecular mechanism of imprinted lncRNA-H19 in fetal growth restriction. 2013/3-2015/2, ¥50000.
7.    Science and Technology Development Fund Key Project of Nanjing Medical University (2012NJMU002): Environment and epigenetics risk factors and their interactions in spermatogenic failure. 2012/12-2014/12, ¥30000.
 URL of their official website:

http://gwxy.njmu.edu.cn/yxjs/ShowArticle.asp?ArticleID=1734 https://www.researchgate.net/profile/Wei_Wu10

List of Publications:

1.        Yuan B, Wu W*, Chen M, Gu H, Tang Q, Guo D, Chen T, Chen Y, Lu C, Song L, Xia Y, Chen D, Rehan V, Sha J, Wang X*. Metabolomics reveals a role of betaine in prenatal DBP exposure-induced epigenetic transgenerational failure of spermatogenesis in rats. Toxicol Sci. 2017; 158 (2): 356-366. (Cover Article)
2.        Tang Q, Chen Y, Wu W*, Ding H, Xia Y, Chen D, Wang X. Idiopathic male infertility and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking. Sci Rep. 2017; 7(1):11219.
3.        Wang L, Hu W, Guan Q, Du G, Chen T, Wu W, Wang Y, Wang X, Xia Y. The association between cooking oil fume exposure during pregnancy and birth weight: A prospective mother-child cohort study. Sci Total Environ. 2017; 612:822-830.
4.        Qiao S, Wu W (co-first author), Chen M, Tang Q, Xia Y, Jia W, Wang X. Seminal plasma metabolomics approach for the diagnosis of unexplained male infertility. PLoS One. 2017; 12(8):e0181115.
5.        Hu W, Chen M, Ji J, Qin Y, Zhang F, Xu M, Wu W, Du G, Wu D, Han X, Jin L, Xia Y, Lu C, Wang X. Interaction between Y chromosome haplogroup O3* and 4-n-octylphenol exposure reduces the susceptibility to spermatogenic impairment in Han Chinese. Ecotoxicol Environ Saf. 2017; 144:450-455.
6.        Pan L, Liu Q, Li J, Wu W, Wang X, Zhao D, Ma J. Association of the VDAC3 gene polymorphism with sperm count in Han-Chinese population with idiopathic male infertility. Oncotarget. 2017; doi: 10.18632/oncotarget.16891.
7.        Chang C, Chen M, Gao J, Luo J, Wu K, Dong T, Zhou K, He X, Hu W, Wu W, Lu C, Hang B, Meeker JD, Wang X, Xia Y. Current pesticide profiles in blood serum of adults in Jiangsu Province of China and a comparison with other countries. Environ Int. 2017; 102:213-222.
8.        Gu H, Wu W*, Yuan B, Tang Q, Guo D, Chen Y, Xia Y, Hu L, Chen D, Sha J, Wang X. Genistein up-regulates miR-20a to disrupt spermatogenesis via targeting Limk1. Oncotarget. 2017; 8(35):58728-58737.
9.        Guo D, Wu W*, Tang Q, Qiao S, Chen Y, Chen M, Teng M, Lu C, Ding H, Xia Y, Hu L, Chen D, Sha J, Wang X. The impact of BMI on sperm parameters and the metabolite changes of seminal plasma concomitantly. Oncotarget. 2017; doi: 10.18632/oncotarget.14950.
10.    Chen T, Xu J, Liu G, Liu H, Chen M, Qin Y, Wu W, Xia Y, Ji C, Guo X, Wen J, Wang X. Genetic variants in PTPRD and risk of gestational diabetes mellitus. Oncotarget. 2016; 7(46):76101-76107.
11.    Ji J, Qin Y, Zhou R, Zang R, Huang Z, Zhang Y, Chen M, Wu W, Song L, Ling X, Shen H, Hu Z, Xia Y, Lu C, Wang X. X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in han chinese population. Oncotarget. 2016; 7(31):49122-49129.
12.    Chang J, Pan F, Tang Q, Wu W*, Chen M, Lu C, Ding H, Hu L, Chen D, Xia Y, Wang X. eNOS gene T786C, G894T and 4a4b polymorphisms and male infertility susceptibility: a meta-analysis. Andrologia. 2016; doi: 10.1111/and.12646.
13.    Hu W, Chen M, Wu W*, Lu J, Zhao D, Pan F, Lu C, Xia Y, Hu L, Chen D, Sha J, Wang X. Gene-gene and gene-environment interactions on risk of male infertility: Focus on the metabolites. Environ Int. 2016; 91:188-195.
14.    Pan B, Li R, Chen Y, Tang Q, Wu W*, Chen L, Lu C, Pan F, Ding H, Xia Y, Hu L, Chen D, Sha J, Wang X. Genetic Association Between Androgen Receptor Gene CAG Repeat Length Polymorphism and Male Infertility: A Meta-Analysis. Medicine (Baltimore). 2016; 95(10):e2878.
15.    Yuan B, Gu H, Xu B, Tang Q, Wu W*, Ji X, Xia Y, Hu L, Chen D, Wang X. Effects of Gold Nanorods on Imprinted Genes Expression in TM-4 Sertoli Cells. Int J Environ Res Public Health. 2016; 13(3). pii: E271.
16.    Lu J, Gu H, Tang Q, Wu W*, Yuan B, Guo D, Wei Y, Sun H, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X. Common SNP in hsa-miR-196a-2 increases hsa-miR-196a-5p expression and predisposes to idiopathic male infertility in Chinese Han population. Sci Rep. 2016; 6:19825.
17.    Zhou R, Wang R, Qin Y, Ji J, Xu M, Wu W, Chen M, Wu D, Song L, Shen H, Sha J, Miao D, Hu Z, Xia Y, Lu C, Wang X. Mitochondria-related miR-151a-5p reduces cellular ATP production by targeting CYTB in asthenozoospermia. Sci Rep. 2015; 5:17743.
18.    Li J, Chen L, Tang Q, Wu W*, Gu H, Liu L, Wu J, Jiang H, Ding H, Xia Y, Chen D, Hu Y, Wang X. The role, mechanism and potentially novel biomarker of microRNA-17-92 cluster in macrosomia. Sci Rep. 2015; 5:17212.
19.    Ji J, Qin Y, Ren J, Lu C, Wang R, Dai X, Zhou R, Huang Z, Xu M, Chen M, Wu W, Song L, Shen H, Hu Z, Miao D, Xia Y, Wang X. Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN. Sci Rep. 2015; 5:16262.
20.    Ju R, Wu W (co-first author), Tang Q, Wu D, Xia Y, Wu J, Wang X. Association Analysis between the Polymorphisms of HSD11B1 and H6PD and Risk of Polycystic Ovary Syndrome in Chinese Population. PLoS One. 2015; 10(10):e0140326.
21.    Lu C, Xu M, Wang R, Qin Y, Ren J, Wu W, Song L, Wang S, Zhou Z, Shen H, Sha J, Hu Z, Xia Y, Miao D, Wang X. A genome-wide association study of mitochondrial DNA in Chinese men identifies two risk single nucleotide substitutions for idiopathic oligoasthenospermia. Mitochondrion. 2015; 24:87-92.
22.    Tang W, Tang J, He J, Zhou Z, Qin Y, Qin J, Li B, Xu X, Geng Q, Jiang W, Wu W, Wang X, Xia Y. SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease. J Cell Mol Med. 2015; 19(6):1197-207.
23.    Ju R, Wu W (co-first author), Fei J, Qin Y, Tang Q, Wu D, Xia Y, Wu J, Wang X. Association analysis between the polymorphisms of HSD17B5 and HSD17B6 and risk of polycystic ovary syndrome in Chinese population. Eur J Endocrinol. 2015; 172(3):227-33.
24.    Tang W, Li H, Tang J, Wu W, Qin J, Lei H, Cai P, Huo W, Li B, Rehan V, Xu X, Geng Q, Zhang H, Xia Y. Specific serum microRNA profile in the molecular diagnosis of Hirschsprung's disease. J Cell Mol Med. 2014; 18(8):1580-7.
25.    Zhao M, Tang Q, Wu W (corresponding author), Xia Y, Chen D, Wang X. miR-20a contributes to endometriosis by regulating NTN4 expression. Mol Biol Rep. 2014; 41(9):5793-7.
26.    Jiang H, Wu W (co-first author), Zhang M, Li J, Peng Y, Miao T, Zhu H, Xu G. Aberrant upregulation of miR-21 in placental tissues of macrosomia. J Perinatol. 2014; 34(9):658-63.
27.    Zhang S, Tang Q, Wu W*, Yuan B, Lu C, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X. Association between DAZL polymorphisms and susceptibility to male infertility: systematic review with meta-analysis and trial sequential analysis. Sci Rep. 2014; 4:4642.
28.    Qin Y, Ji J, Du G, Wu W, Dai J, Hu Z, Sha J, Hang B, Lu C, Xia Y, Wang X. Comprehensive pathway-based analysis identifies associations of BCL2, GNAO1 and CHD2 with non-obstructive azoospermia risk. Hum Reprod. 2014; 29(4):860-6.
29.    Qin Y, Du G, Chen M, Hu W, Lu C, Wu W, Hang B, Zhou Z, Wang X, Xia Y. Combined effects of urinary phytoestrogens metabolites and polymorphisms in metabolic enzyme gene on idiopathic male infertility. Arch Toxicol. 2014; 88(8):1527-36.
30.    Zhou Z, Qin J, Tang J, Li B, Geng Q, Jiang W, Wu W, Rehan V, Tang W, Xu X, Xia Y. Down-regulation of MeCP2 in Hirschsprung's disease. J Pediatr Surg. 2013; 48(10):2099-2105.
31.    Tang W, Qin J, Tang J, Zhang H, Zhou Z, Li B, Geng Q, Wu W, Xia Y, Xu X. Aberrant reduction of MiR-141 increased CD47/CUL3 in Hirschsprung's disease. Cell Physiol Biochem. 2013; 32(6):1655-67.
32.    Xu M, Qin Y, Qu J, Lu C, Wang Y, Wu W, Song L, Wang S, Chen F, Shen H, Sha J, Hu Z, Xia Y, Wang X. Evaluation of Five Candidate Genes from GWAS for Association with Oligozoospermia in a Han Chinese Population. PLoS One. 2013; 8(11):e80374.
33.    Lu C, Xu M, Wang R, Qin Y, Wang Y, Wu W, Song L, Wang S, Shen H, Sha J, Miao D, Hu Z, Xia Y, Wang X. Pathogenic variants screening in five non-obstructive azoospermia-associated genes. Mol Hum Reprod. 2013; 20(2):178-83.
34.    Tang Q, Li J, Zhang S, Yuan B, Sun H, Wu D, Lu C, Wu W (corresponding author), Xia Y, Ding H, Hu L, Chen D*, Sha J*, Wang X. GSTM1 and GSTT1 Null Polymorphisms and Childhood Acute Leukemia Risk: Evidence from 26 Case-Control Studies. PLoS One. 2013; 8(10):e78810.
35.    Xu S, Xu P, Wu W, Ou Y, Xu J, Zhang G, Li J, Xu G. The biphasic expression pattern of miR-200a and E-cadherin in epithelial ovarian cancer and its correlation with clinicopathological features. Curr Pharm Des. 2014; 20(11):1888-95.
36.    Wu W*, Lu J, Tang Q, Zhang S, Yuan B, Li J, Di Wu, Sun H, Lu C, Xia Y, Chen D, Sha J, Wang X. GSTM1 and GSTT1 null polymorphisms and male infertility risk: an updated meta-analysis encompassing 6934 subjects. Sci Rep. 2013; 3:2258.
37.    Xu C, Song RJ, Yang J, Jiang B, Wang XL, Wu W, Zhang W. Klotho gene polymorphism of rs3752472 is associated with the risk of urinary calculi in the population of Han nationality in Eastern China. Gene. 2013; 526(2):494-7.
38.    Lu C, Wang Y, Zhang F, Lu F, Xu M, Qin Y, Wu W, Li S, Song L, Yang S, Wu D, Jin L, Shen H, Sha J, Xia Y, Hu Z, Wang X. DAZ duplications confer the predisposition of Y chromosome haplogroup K* to non-obstructive azoospermia in Han Chinese populations. Hum Reprod. 2013; 28(9):2440-9.
39.    Wu W*, Lu J, Chen D, Yuan B, Qin Y, Han X, Niu X, Xu B, Lu C, Xia Y, Sha J, Wang X. Association of prostate cancer susceptibility variant (MSMB) rs10993994 with risk of spermatogenic failure. Gene. 2013; 524:197-202.
40.    Tang W, Li B, Tang J, Liu K, Qin J, Wu W, Geng Q, Zhang J, Chen H, Xu X, Xia Y. Methylation analysis of EDNRB in human colon tissues of Hirschsprung's disease. Pediatr Surg Int. 2013; 29:683-8.
41.    Lv Q, Lu J, Wu W, Sun H, Zhang J. Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with stroke risk based on a meta-analysis. Genet Mol Res. 2013; 12(4):6882-94.
42.    Wu W, Qin Y, Li Z, Dong J, Dai J, Lu C, Guo X, Zhao Y, Zhu Y, Zhang W, Sha J, Shen H, Xia Y, Hu Z, Wang X. Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p. Hum Reprod. 2013; 28:1827-36.
43.    Qin Y, Chen M, Wu W (co-first author), Xu B, Tang R, Chen X, Du G, Lu C, Meeker JD, Zhou Z, Xia Y, Wang X. Interactions between Urinary 4-tert-Octylphenol Levels and Metabolism Enzyme Gene Variants on Idiopathic Male Infertility. PLoS One. 2013; 8:e59398.
44.    Tang Q, Wu W (co-first author), Xu X, Huang L, Gao Q, Chen H, Sun H, Xia Y, Sha J, Wang X, Chen D, Xu Q. miR-141 Contributes to Fetal Growth Restriction by Regulating PLAG1 Expression. PLoS One. 2013; 8:e58737.
45.    Lu C, Xu M, Wang Y, Qin Y, Du G, Wu W, Han X, Ji C, Yang Y, Gu A, Xia Y, Song L, Wang S, Wang X. Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese population. PLoS One. 2013; 8:e53443.
46.    Xu S, Wu W (co-first author), Sun H, Lu J, Yuan B, Xia Y, Moor B, Marchal K, Wang X, Xu P, Cheng W. Association of the vascular endothelial growth factor gene polymorphisms (-460C/T, +405G/C, and +936T/C) with endometriosis: a meta-analysis. Ann Hum Genet. 2012; 76:464-471.
47.    Chen M, Xu B, Ji W, Qiao S, Hu N, Hu Y, Wu W, Qiu L, Zhang R, Wang Y, Wang S, Zhou Z, Xia Y, Wang X. Bisphenol A Alters n-6 Fatty Acid Composition and Decreases Antioxidant Enzyme Levels in Rat Testes: A LC-QTOF-Based Metabolomics Study. PLoS One. 2012; 7:e44754.
48.    Tang W, Li B, Xu X, Zhou Z, Wu W, Tang J, Qin J, Geng Q, Jiang W, Zhang J, Sha J, Xia Y, Wang X. Aberrant high expression of NRG1 gene in Hirschsprung disease. J Pediatr Surg. 2012; 47:1694-1698.
49.    Han X, Tang R, Chen X, Xu B, Qin Y, Wu W, Hu Y, Xu B, Song L, Xia Y, Wang X. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) decreases progesterone synthesis through cAMP-PKA pathway and P450scc downregulation in mouse Leydig tumor cells. Toxicology. 2012; 302:44-50.
50.    Zhao D, Wu W (co-first author), Xu B, Niu X, Cui H, Zhang Y, Wang Z, Wang X. Variants in the SRD5A2 gene are associated with quality of semen. Mol Med Report. 2012; 6:639-644.
51.    Wu W, Hu Z, Qin Y, Dong J, Dai J, Lu C, Zhang W, Shen H, Xia Y, Wang X. Seminal plasma microRNAs: potential biomarkers for spermatogenesis status. Mol Hum Reprod. 2012; 18:489-497.
52.    Wu W, Cai H, Sun H, Lu J, Zhao D, Qin Y, Han X, Niu X, Lu C, Xia Y, Wang S, De Moor B, Marchal K, Wang X. Follicle stimulating hormone receptor G-29A, 919A>G, 2039A>G polymorphism and the risk of male infertility: A meta-analysis. Gene. 2012; 505:388-392.
53.    Qin Y, Xia Y, Wu W, Han X, Lu C, Ji G, Chen D, Wang H, Song L, Wang S, Wang X. Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population. Reprod Biomed Online. 2012; 24:454-461.
54.    Shen O, Liu R, Wu W (co-first author), Yu L, Wang X. Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with male infertility: a meta-analysis. Ann Hum Genet. 2012; 76:25-32.
55.    Lu C, Zhang F, Yang H, Xu M, Du G, Wu W, An Y, Qin Y, Ji G, Han X, Gu A, Xia Y, Song L, Wang S, Jin L, Wang X. Additional genomic duplications in AZFc underlie the b2/b3 deletion-associated risk of spermatogenic impairment in Han Chinese population. Hum Mol Genet. 2011; 20:4411-4421.
56.    Shen O, Wu W (co-first author), Du G, Liu R, Yu L, Sun H, Han X, Jiang Y, Shi W, Hu W, Song L, Xia Y, Wang S, Wang X. Thyroid Disruption by Di-n-Butyl Phthalate (DBP) and Mono-n-Butyl Phthalate (MBP) in Xenopus laevis. PLoS One. 2011; 6:e19159.
57.    Wu W, Shen O, Qin Y, Lu J, Niu X, Zhou Z, Lu C, Xia Y, Song L, Wang S, Wang X. Methylenetetrahydrofolate reductase C677T polymorphism and the risk of male infertility: a meta-analysis. Int J Androl. 2012; 35:18-24.
58.    Wu W, Shen O, Qin Y, Niu X, Lu C, Xia Y, Song L, Wang S, Wang X. Idiopathic Male Infertility Is Strongly Associated with Aberrant Promoter Methylation of Methylenetetrahydrofolate Reductase (MTHFR). PLoS One. 2010; 5: e13884.
59.    Wu W, Lu C, Xia Y, Shen O, Ji G, Gu A, Song L, Wang X. Lack of association between DAZ gene methylation patterns and spermatogenic failure. Clin Chem Lab Med. 2010; 48: 355-360.
60.    Shen O, Du G, Sun H, Wu W, Jiang Y, Song L, Wang X. Comparison of in vitro hormone activities of selected phthalates using reporter gene assays. Toxicol Lett. 2009; 191: 9-14.
61.    Lu C, Zhang J, Li Y, Xia Y, Zhang F, Wu B, Wu W, Ji G, Gu A, Wang S, Jin L, Wang X. The b2/b3 subdeletion shows higher risk of spermatogenic failure and higher frequency of complete AZFc deletion than the gr/gr subdeletion in a Chinese population. Hum Mol Genet. 2009; 18:1122-1130.

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Sex and Reproduction

Published On: April 12, 2018 | Pages: 001 - 005

Author(s): Mohamed Nabih EL-Gharib* and Sherin Barakat Albehoty
Abstract View Full Article View DOI: 10.17352/ijsrhc.000001