Research Interest: Genitourinary Cancer
Research Interest: Gene therapy, Cell and tissue
engineering, Vaccine development, Biomaterials, Synthetic biology and biomass,
Research Interest: Research interests are varied and
include detection and utilisation of novel biomarkers of toxicological exposure.
Research Interest: Immune based inflammatory disorders
(with special reference to nanomedicines).
Research Interest: Inflammatory bowel diseases coeliac
disease, Cystic fibrosis.
Research Interest: Currently, his studies focus on the
two major directions. The first one is to study the innate receptor TLR and NLR
ligands as adjuvant for CTL epitope-based vaccines to treat cancer and the
adjuvant effect on the modulation of immune responses will be studied.
Research Interest: Molecular biology of viruses, the
interactions of viruses with host cells, the pathogenesis of viral diseases,
the post-translational modification of viral proteins, and mechanisms of host
defense. The research works are designed to increase fundamental knowledge as
well as to facilitate the development of new approaches to control of viral
Research Interest: Self-nonself discrimination in innate immunity, Host-pathogen
interactions Autoimmune diseases.
Research Interest: Structure-to-function relationships of
microbial lectins Structural study of multivalent protein-carbohydrate
interactions Analysis of differential glycosylation and bacterial infection
pathology during metabolic imbalance Structure-based design of anti-bacterial
and anti-fungal drugs.
Research Interest: Bacteria of the genus Staphylococcus,
in particular the species S. aureus and virulence factors produced by this
species. In the so far carried out research, the results of which were
published in several peer-reviewed journals I analyzed:
1.The influence of
leucocytotoxic and superantygenic virulence factors produced by S. aureus
strains isolated from milk of cows with mastitis on the cytokine production and
gene expression in bovine leukocyte cultures in vitro;
2. the impact of staphylococcal exotoxins on the process of phagocytosis in vitro;
3. the efficacy of treatment of mastitis by staphylococcal autovaccine;
4. the profile of resistance to methicillin of coagulase-negative staphylococci isolated from animals;
5. the profile of the genes encoding superantigens in S. aureus and S. xylosus isolates collected from cows;
6. the possibility of transfer of genes encoding superantigens between staphylococci occurring in the same mammary gland;
7. genetic relatedness of staphylococci isolated within a herd of animals;
8. the biological activity of staphylococcal exosecretions against leukocytes in vitro;
9. the impact of staphylococcal virulence factors on the morphology of leukocytes in vitro.
I also analyzed and published in the GenBank several new 16S rRNA gene sequences of bacteria representing different species of staphylococci, identified by PCR-RFLP analysis of gap gene. Furthermore, as a contributor I published in the GenBank the 16S rRNA gene sequences of bacterial isolates, which were unidentified based on the polymorphism of gap gene, of which at least two isolates represent new species or subspecies of the staphylococci.
The second direction of my research concerns the use of magnetic fields, in particular the rotating magnetic field to modify the functional parameters and pathogenicity potential of different species of microorganisms. At the present, I’m analyzing the influence of magnetic field on metabolic processes in microorganisms, both at the cellular and molecular level. As a continuation of my first research mainstream microorganism used in these studies is primarily S. aureus.
Research Interest: Nanomedicine, Controlled/Targeted Drug Delivery,
Toxicology, Pharmacology, Cellular Interaction, Nanofilms and Microcapsules,
Biomimetic, Microbiology, Immunology.
Research Interest: Epigenetic regulation of virus or
autoimmune diseases on host immune cells such as Treg, Th17 and innate lymphoid
Research Interest: Pathogenesis and Treatment of Melanoma, and in Part are directed at
Developing Tools to Study Melanoma.
Research Interest: Infection diseases prevention,
epidemiology of infectious diseases, vaccination, vaccines, travel and tropical
Research Interest: He focused on developing novel
adjuvants and vaccine delivery systems for prophylactic vaccination along with
rational design of new vaccine formulations for Novartis discovery projects.
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