Research Interest: Structure-to-function relationships of
microbial lectins Structural study of multivalent protein-carbohydrate
interactions Analysis of differential glycosylation and bacterial infection
pathology during metabolic imbalance Structure-based design of anti-bacterial
and anti-fungal drugs.
Research Interest: Basic Biology/Physiology Of Salivary
Glands, Prevention Of Radiation-Induced Salivary Gland Damage, Gene Transfer To
Salivary Glands, Viral Vector Modification And Improving Viral Vectors For Gene
Research Interest: Infectious diseases in animals,
diagnostics, epidemiology, efficiency of vaccination programmes.
Research Interest: Nanomedicine, Controlled/Targeted Drug Delivery,
Toxicology, Pharmacology, Cellular Interaction, Nanofilms and Microcapsules,
Biomimetic, Microbiology, Immunology.
Research Interest: Virology/Microbiology, Biochemistry, Clinical Diagnostics, Molecular
Biology, Protein Chemistry.
Research Interest: Bacteria of the genus Staphylococcus,
in particular the species S. aureus and virulence factors produced by this
species. In the so far carried out research, the results of which were
published in several peer-reviewed journals I analyzed:
1.The influence of
leucocytotoxic and superantygenic virulence factors produced by S. aureus
strains isolated from milk of cows with mastitis on the cytokine production and
gene expression in bovine leukocyte cultures in vitro;
2. the impact of staphylococcal exotoxins on the process of phagocytosis in vitro;
3. the efficacy of treatment of mastitis by staphylococcal autovaccine;
4. the profile of resistance to methicillin of coagulase-negative staphylococci isolated from animals;
5. the profile of the genes encoding superantigens in S. aureus and S. xylosus isolates collected from cows;
6. the possibility of transfer of genes encoding superantigens between staphylococci occurring in the same mammary gland;
7. genetic relatedness of staphylococci isolated within a herd of animals;
8. the biological activity of staphylococcal exosecretions against leukocytes in vitro;
9. the impact of staphylococcal virulence factors on the morphology of leukocytes in vitro.
I also analyzed and published in the GenBank several new 16S rRNA gene sequences of bacteria representing different species of staphylococci, identified by PCR-RFLP analysis of gap gene. Furthermore, as a contributor I published in the GenBank the 16S rRNA gene sequences of bacterial isolates, which were unidentified based on the polymorphism of gap gene, of which at least two isolates represent new species or subspecies of the staphylococci.
The second direction of my research concerns the use of magnetic fields, in particular the rotating magnetic field to modify the functional parameters and pathogenicity potential of different species of microorganisms. At the present, I’m analyzing the influence of magnetic field on metabolic processes in microorganisms, both at the cellular and molecular level. As a continuation of my first research mainstream microorganism used in these studies is primarily S. aureus.
Research Interest: Cancer immunology, vaccines, cancer,
antigen-presenting cells and viral immunology.
Research Interest: Vaccine development, bacteriology
& microbiology including technologies that directly support vaccine
Research Interest: The structure of sulfated
polysaccharides extracts from seaweeds. The activity of sulfated
polysaccharides such as nephrophaty and Parkinsion Disease. The comprehensive
utilization of seaweeds especially Saccharina japonica.
Research Interest: Pediatrics, Clinical Immunology, Viral
immunology, Vaccine and infectious diseases.
Research Interest: Cytokine based Immunotherapies to
treat lymphopenia, Clinical biomarkers in psychological disorders, Effects of
Inflammation on hematopoiesis.
Research Interest: Immunology such as Autoimmune Diabetes.
Research Interest: Currently, his studies focus on the
two major directions. The first one is to study the innate receptor TLR and NLR
ligands as adjuvant for CTL epitope-based vaccines to treat cancer and the
adjuvant effect on the modulation of immune responses will be studied.
Research Interest: A specialist in pediatrics and
Research Interest: Self-nonself discrimination in innate immunity, Host-pathogen
interactions Autoimmune diseases.
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