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Clinical Group

Open Journal of Parkinson's Disease and Treatment 

    Recent articles to be released shortly in Volume-2

    Genes involved in the development of Parkinson

    Published On: October 14, 2017 | Pages: 039 - 051

    Author(s): Diana Teixeira and Inês Lopes Cardoso*
    Background: Parkinson’s disease is the second most important neurodegenerative disorder, affecting 3% of individuals older than 80 years of age. Main clinical symptoms are resting tremor, postural instability, bradykinesia and rigidity, with a good response to levodopa therapy. ...
    Abstract View Full Article View DOI: 10.17352/ojpdt.000005

    Divergent Effects of Haloperidol on Motor Versus Spatial Functions

    Published On: September 20, 2017 | Pages: 032 - 038

    Author(s): Robert Lalonde* and Catherine Strazielle
    The effects of haloperidol on motor versus cognitive factors were determined in mice. Haloperidol decreased open-field activity and impaired motor coordination in suspended bar and rotorod tests. The drug also augmented escape latencies in swimming towards submerged or visible goals in the Morris water maze without increasing path length or affecting the probe test of ...
    Abstract View Full Article View DOI: 10.17352/ojpdt.000004

    A proposal for a semantic change in the current diagnostic criteria of Parkinson’s disease Psychosis

    Published On: July 06, 2017 | Pages: 030 - 031

    Author(s): Francisco Appiani, Marcelo Miranda, Carlos Zúniga-Ramírez, Michel Saenz-Farret, Vanderci Borges and Federico Micheli*
    Psychosis may emerge as part of Parkinson’s disease (PD) process but is also associated with PD treatment. When the NINDS-NIMH criteria were applied to a cross-sectional PD cohort ...
    Abstract View Full Article View DOI: 10.17352/ojpdt.000003

    Effectiveness of deep Brain Stimulation on early onset Dystonia: A Case Report

    Published On: June 10, 2017 | Pages: 027 - 029

    Author(s): Ayse Unal, Ali Yalman, Filiz Altug* and Uğur Cavlak
    Dystonia is defi ned as a movement disorder characterized by involuntary muscular contractions that generate twisting and repetitive movements and/or abnormal postures [1]. ...
    Abstract View Full Article View DOI: 10.17352/ojpdt.000002

    Restoration of Mitochondrial Dysfunction in 6-Hydroxydopamine Induced Parkinson’s disease: a Complete Review

    Published On: April 26, 2017 | Pages: 001 - 026

    Author(s): Sidharth Mehan*, Gurpreet Kaur, Rajesh Dudi, Manju Rajput and Sanjeev Kalra
    Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by neuronal cell death in the specifi c brain region like basal ganglia, cerebral cortex and hippocampus. Symptoms associated with PD patients are rigidity, akathesia, tremor, postural imbalance, cognitive and memory dysfunctions. ...
    Abstract View Full Article View DOI: 10.17352/ojpdt.000001

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