Research Interest: Cancer Biology, Cell Biology, Breast Cancer, Cancer
Prevention, Anti-Cancer Drug Development, Cancer Metastasis, Transcription
Factors, Kinase, Glucose Metabolism.
Research Interest: Neurology
Research Interest: Drug Discovery and Development.
Research Interest: Bone Marrow
Transplantation, Immunology, Autoimmunity, Thymus and Bone Marrow
Derived-Mesenchymal Stem Cells. His Cutting-Edge Technology for Bone Marrow
Cell Harvesting and Intra-Bone Marrow-Bone Marrow Transplantation has Led to
Significant Research Into Allogeneic Stem Cell Transplantation.
Research Interest: Clinical Pharmacology, Gastroenterology, Pharmaceutical Development, Drug Development, Colorectal Cancer, Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease
Research Interest: In his Consulting Experience, Devyn Led a Wide
Range of Projects, Across Multiple Therapeutic Areas and a Host of Technology
Platforms, Including Basic R&D Tools, Regenerative Medicine, Gene Therapy and
Research Interest: Effects of Chinese Herbal Medicine on Osteogenesis
and Adipogenesis of Mesenchymal Stem Cells, Inhibitory Effects of Chinese Herbal
Medicine on RANKL-Induced Osteoclastgenesis of RAW264.7 Cells, Effect of Chinese
Herbal Medicine on Different Osteoporotic Rat Models, Establishment of the
Screening Platform for Neuro-Regenerative Chinese Herbal Medicine by Using Rat
Mesenchymal Stem Cells, Topical Application of Chinese Medicine in
Musculoskeletal Injuries, Wound Healing, Cancer Stem Cells, Neuroprotection.
Years She Extended her Initial Research Interests on Endothelial Progenitor
Cell (EPC) Biology and their Potential use in Regenerative Medicine.
Research Interest: Stem Cell Biology; Breast Cancer Dormancy; Neural
Regulation of Hematopoiesis, the Immunology and Clinical Application of Adult
Human Mesenchymal Stem Cells.
Research Interest: Neuropsychopharmacology of Lipid Transmitters (CTS643,
Andalusian Ministry of Economy, Innovation, Science and Employment): The Group is
Formed in the University Regional Hospital of Malaga, in Collaboration with the
University of Malaga, and Integrated Into the Biomedical Research Institute of Malaga
(IBIMA). Our Interest Focuses on the Role that Regulatory Lipid Molecules,
Mainly Lysophosphatidic Acid, Exerted on the Central Nervous System and Related
Mainly to the Neural Genesis (Neurogenesis / Gliogenesis) and its Effect on
Behavioral Level. It Also Examines the Role of Lysophosphatidic Acid in the
Dynamic Processes that Regulate Neuroinflammation and Demyelination in Multiple
Sclerosis, Studying Animal Models and Samples from Patients with Multiple
Sclerosis, As Well As Mesenchymal Cell Therapy for the Disease.
Research Interest: Harnessed the Biological Principle that Pregnancy and
Hormones Mimicking Pregnancy Induced Breast Cancer Prevention. The Preventive Effect of Pregnancy is
Mediated by the Induction of Differentiation of the Mammary Gland. In Studies Performed in Humans, He has Found that
During the Post-Menopausal Years the Breast of Both Parous and Nulliparous
Women Contains Preponderantly Lob 1 that Differs Biologically By Exhibiting
Different Susceptibility to Carcinogenesis, And Remodeling Of Chromatin That
Emerges As Novel Marker For Defining The Concept Of Differentiation In The
Adult Breast. His Laboratory Has Studied
The Genomic Profile Of Nulliparous And Parous Women In The Premenopausal And
Postmenopausal Period And Find That There Are Genes Only Activated During The
First Five Years After Pregnancy That May Contribute To The Increased Risk
Experimented By Certain Women After Pregnancy And At The Same Time They Have
Confirmed That Pregnancy Induces A Long Lasting Genomic Signature That Start
After Pregnancy That Explain Its Preventive Effect. The Molecular Mechanism
Related To Prevention Is Around The Chromatin Remodeling Process. Using The In
Vitro In Vivo Model Developed In His Laboratory He Is Identifying Drugs That
Can Control Chromatin Remodeling As A Preventive Strategy.
Research Interest: Stem Cell Injection, Cardiovascular Disease,
Medical Diffusion in Arteries, Hemodynamics.
Research Interest: As Is Clear From The Biography, Shigetaka Asano Accomplisheddistinguished
Performance In Research Based On Medical Needs By Full Of Enthusiasm With
State-Of-The-Art New Technology, Such As 1. Verification Of Existence Of Rabbit
Neutrophil Cell Membrane Knack+-Atpase, 2. Discovery Of Laterarity Of Mouse
Intestinal Mucous Membrane Proteins, 3. Finding Of Human Tumor Cell Mediated By
Granulocyte Colony-Stimulating Factor (G-CSF; Bioactive Substance To Stimulate
Differentiation, Proliferation And Functional Activity Of Neutrophil), 4. Analysis
Of Human G-CSF Activity, 5. Succeeding In Incubation Of Human Tumor
Infiltrating T Lymphocyte Colony, 6. Discovery Of Allogenicimmunosuppression Of
Placenta Decidual Cells, 7. Differentiation Induction Of Mesenchymalstem Cell,
8. Cloning Of G-Csfcdna And Development Of Recombinant Human Native G-CSF (Lenograstim)
As The 1st Generation Biomedicine, 9. Constitution Of International Clinical
Guideline For Transplantation Of Bone-Marrow And Cord Blood, And Construction
Of Public Bank Of Bone-Marrow And Cord Blood, 10. Non-Clinical Study Of Human
Granulocyte Colony-Stimulating Factor (GM-CSF; Bioactive Substance To Stimulate
Differentiation, Proliferation And Functional Activity Of Macrophage Besides
Neutrophil)Immunogene Therapy And Execution Of The Phase Iia Clinical Study,
11. Non-Clinical Study Of Utilizing Maxizyme For Immunogene Therapy Of Myeloid
Leukemia Cell, 12. Acquisition And Molecular Analysis Of Leukemia Stem Cell
Like Property By Stochastic Adhesion Of In Vitro Human Myelogenous Leukemic
Cell Line Cell And Stromal Cell, 13. Pathological Analysis Of Mesenchymalstem
Cell(Parental Cell Of Range Of Cell Consist Ofstroma) Differentiation And
Proliferation In Translin(Substance Found As Molecule To Bind Fusion Gene Of
Lymphatic Leukemia) Knockout Mouse.
Two Major Projects are Currently Underway in the Laboratory.
A Cell Reprogramming Technique Has Been Used to Convert Heterogeneous Malignant Breast Cancer Cells into Induced Pluripotent Stem Cells Using Sox2/Oct4/Nanog Proteins. Dr. Wu’s Laboratory is Clarifying these Induced Pluripotent Stem Cells for their Differentiation Potential and Oncogenic Properties, and Try to Develop a Novel Cell Converting Therapy for Malignant Breast Cancer Treatment.
Metastasis, the Spread of Cancer Cells from the Primary Tumor To Distant Organs, Is The Most Dreadful Development Of Breast Cancer, As Well As Other Neoplastic Diseases. Although Metastasis Contributes To Over 90% Of Human Cancer Mortality, The Molecular Mechanism Of This Process Remains Largely Unknown. Dr. Wu’s Laboratory Is In The Process Of Identifying Molecular Signatures Involved In Breast Cancer Metastasis Using Integrative Genetic, Epigenetic And Proteomic Approach, As Well As Animal Models And Clinical Specimens.
Research Interest: Tumor Immunology and Immunotherapy, Cancer Stem
Cell Biology and Immunology, Obstetrics and Gynecology.
Published On: April 01, 2017 | Pages: 006 - 015Abstract View Full Article View DOI: 10.17352/sscrt.000011
Published On: March 21, 2017 | Pages: 001 - 005Abstract View Full Article View DOI: 10.17352/sscrt.000010
Published On: December 29, 2016 | Pages: 025 - 032Abstract View Full Article View DOI: 10.17352/sscrt.000009
Published On: December 29, 2016 | Pages: 017 - 024Abstract View Full Article View DOI: 10.17352/sscrt.000008
Published On: December 13, 2016 | Pages: 007 - 016Abstract View Full Article View DOI: 10.17352/sscrt.000007
Published On: November 29, 2016 | Pages: 001 - 006Abstract View Full Article View DOI: 10.17352/sscrt.000006
Published On: December 31, 2015 | Pages: 017 - 018Abstract View Full Article View DOI: 10.17352/sscrt.000005
Published On: December 31, 2015 | Pages: 012 - 016Abstract View Full Article View DOI: 10.17352/sscrt.000004
Published On: December 08, 2015 | Pages: 004 - 011Abstract View Full Article View DOI: 10.17352/sscrt.000003